Abstract
Levothyroxine is a common agent which is used in thyroid replacement therapy. It has a large scale of symptoms in patients which expose to high doses. Most of the patients remains asymptomatic and only a small amount comes up with symptoms. There haven't been any established trade protocols for levothyroxine intoxication in adults. In this case, we report a 19 year old levothyroxin intoxication patient, required intensive care treatment. Patient had gastrointestinal lavage, activated charcoal, propylthiouracil, propranolol and prednisolone therapy. Patient didn't have any thyrotoxicosis symptoms and discharced.
Keywords
References
- 1. D.A. de Luis, A.Duenas, J.Martin, L. Abad, L. Cuellara, R. Aller. Light Symptoms following a High-Dose Intentional L Thyroxine Ingestion Treated with Cholestyramine. Horm Res 2002; 57: 61-63.
- 2. Lehrner LM, Weir MR. Acute ingestions of thyroid hormones. Pediatrics 1984; 73: 313-317.
- 3. Gorman RL, Chamberlain JM, Rose SR, Oderda GM. Massive levothyroxine overdose: High anxiety-low toxicity. Pediatrics 1988; 82: 666-669.
- 4. Shilo L, Kovatz S, Hadari R, Weiss E, Nabriski D,Shenkman L. Massive thyroid hormone overdose: Kinetics, clinical manifestations and management. Isr Med Assoc J 2002; 4: 298- 299.
Abstract
Levotiroksin, tiroid hormon replasman tedavisinde çok kullanılan bir ajandır. Yetişkinlerde yüksek doz levotiroksin maruziyetine bağlı olarak geniş yelpazede semptomlar ortaya çıkmaktadır. Yetişkin hastaların çoğu asemptomatik seyretmektedir. Uygun tedavi protokolleri hala kesinleşmemiştir. Bu sunumda 19 yaşında levotiroksin intoksikasyonu nedeniyle yoğun bakım ünitesinde takip edilen bir olgu sunuldu. Olguya gastrik lavaj, aktif kömür, propiltiourasil, propranolol ve prednizolon tedavisi uygulandı. Bu olgu, yüksek doz levotiroksin almasına rağmen uygun tedavi ile tirotoksikoz belirtileri gelişmeden hasta düzelerek taburcu edildi.
Keywords
References
- 1. D.A. de Luis, A.Duenas, J.Martin, L. Abad, L. Cuellara, R. Aller. Light Symptoms following a High-Dose Intentional L Thyroxine Ingestion Treated with Cholestyramine. Horm Res 2002; 57: 61-63.
- 2. Lehrner LM, Weir MR. Acute ingestions of thyroid hormones. Pediatrics 1984; 73: 313-317.
- 3. Gorman RL, Chamberlain JM, Rose SR, Oderda GM. Massive levothyroxine overdose: High anxiety-low toxicity. Pediatrics 1988; 82: 666-669.
- 4. Shilo L, Kovatz S, Hadari R, Weiss E, Nabriski D,Shenkman L. Massive thyroid hormone overdose: Kinetics, clinical manifestations and management. Isr Med Assoc J 2002; 4: 298- 299.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | August 1, 2010 |
| Published in Issue | Year 2010 Volume: 15 Issue: 4 |