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Determination of the Role of Mean Corpuscular Volume Level on the Diagnosis of Alcoholic Liver Cirrhosis and Investigation of Its Effect on the Prognosis

Year 2008, Volume: 13 Issue: 1, 49 - 52, 01.02.2008

Abstract

Objectives: In this study, we aimed to determine the relationship between macrocytosis and Alcoholic Liver Cirrhosis (ALC) and its accuracy, sensitivity and specificity rates. Material and Methods: Mean corpuscular volume (MCV) levels of 46 patients diagnosed as having ALC (Group 1) and 51 patients diagnosed as having Hepatitis B cirrhosis and Hepatitis C cirrhosis (Group 2) were compared retrospectively. Results: MCV level determined as 94.6±10.87 in patients in Group 1 was statistically significantly higher than in patients in Group 2 (p

References

  • Rutherford CJ, Frenkel PF. Hemostatic disorders in liver disease. In:Schiff ER, Sorrell MF, Maddrey WC (Editors). Schiff’s Diseases of the Liver. 8. edition , Philedelphia-New York: Lippincott-Raven Publishers, 1999: 583-598
  • Pasqualetti P, Festuccia V, MacCarone C, DiLaura G, Casale R. Diagnostic value of gamma glutamyl transpeptidase and the mean corpusculer volume in chronic hepatitis of alcoholic etiology. Minerva Med 1995; 86: 395-402
  • Soysal T. Megaloblastic Anemias. In: Soysal T, Soycan LY (Editors). Continuous Medical Education Symposium Serial of Cerrahpasa Medical Faculty of Istanbul University. Istanbul: Kaya Publishers, 2001: 33-47
  • Mates M, Heyd J, Soununjon M et all. The haematologist as watcdog of community health by full blood count. QJM 1995; 88: 333-339
  • Riedler GF, Zollinger P, Schmid M. Changes in the blood picture in liver diseases. Schweiz Med Wochenshr 1975; 105: 1593
  • Intragumtornchai T, Rojnukkarin Vajanamarhutue C, Israsena S. Anemias in Thai patients with cirrhosis. Int J Hematol(Ireland) 1997; 65: 365-373 P, Swasdikul D,
  • Maruyama S, Hirayama C, Yamamato et all. Red blood cell status in alcoholic and non-alcoholic liver diseases. J Lab Med 2001: 138: 332-337
  • Sherlock S, Dooley J. Alcohol and liver. In:Sherlock S, Dooley J (Editors). Diseases of the liver and biliary system. 10. baskı, Oxford: Blackwell Science Ltd, 1997: 385-400
  • Wu A, Chanarin I, Slavin G, Levi AJ. Folate deficiency in the alcoholics-its relationship to clinical and haematological abnormalities, liver disease and folate stores. Br Haematol 1975; 29: 469-478
  • Seppa K, Sillanaukee P. Women, alcohol and red cells. Alcohol Clin Exp Res. 1994: 18: 1168-1171
  • Oski FA. Anemia due to other nutritional deficiencies. In: Beutler E, Lichtman MA, Coller BS, Kipps TJ (Editors). Williams Hematology. 5. baskı, McGraw Hill Health Professions Division International Edition, 1995: 511-514
  • Balcells A, Ingelmo M, Vivancos J et all. Macrocytosis in chronic alcoholism (author’s transl). Med Clin (barc) 1979; 73 :312-314
  • Gheno G, Magnabosco V, Mazzei G. Macrocytosis and anemia in chronic alcoholism. Correlation with the results of hepatic needle biopsy. Minerva Med 1981; 72: 1301-1306
  • Yersin B, Nicolet JF, Dercy et all. Screening for excessive alcohol drinking; comparative value of carbohaydrate deficient transferin, gamma glutamyl transpeptidase and mean corpuscular volume. Arch Intern Med 1995; 155: 1907-1911
  • Sun L, Konig IR, Jacobs A, et al. Mean corpuscular volume and ADH1C genotype in white patients with alcohol-associated diseases. Alcohol Clin Exp Res 2005;29:788-93
  • Kabul Tarihi: 02.11.2007

Ortalama Eritrosit Hacmi Düzeyinin Alkolik Karaciğer Sirozu Tanısındaki Yerinin Belirlenmesi ve Prognoza Etkisinin İrdelenmesi

Year 2008, Volume: 13 Issue: 1, 49 - 52, 01.02.2008

Abstract

Amaç: Alkolik karaciğer sirozunda(AKS) makrositoz sıklığı ve makrositoz ile prognoz arasındaki ilişkinin belirlenerek doğruluk, duyarlılık ve özgüllük değerlerinin tespiti amaçlanmıştır. Gereç ve Yöntem: AKS tanısı olan toplam 46 hasta(grup 1)ile Hepatit B ve C virüslerine bağlı karaciğer sirozu (KS)tanısı olan 51 hastanın(grup 2) ortalama eritrosit hacmi(OEH) düzeyleri retrospektif olarak karşılaştırıldı. Bulgular: Grup 1'de OEH değeri 94.6±10.87 olup, grup 2 hastalardan anlamlı olarak yüksek saptandı(p

References

  • Rutherford CJ, Frenkel PF. Hemostatic disorders in liver disease. In:Schiff ER, Sorrell MF, Maddrey WC (Editors). Schiff’s Diseases of the Liver. 8. edition , Philedelphia-New York: Lippincott-Raven Publishers, 1999: 583-598
  • Pasqualetti P, Festuccia V, MacCarone C, DiLaura G, Casale R. Diagnostic value of gamma glutamyl transpeptidase and the mean corpusculer volume in chronic hepatitis of alcoholic etiology. Minerva Med 1995; 86: 395-402
  • Soysal T. Megaloblastic Anemias. In: Soysal T, Soycan LY (Editors). Continuous Medical Education Symposium Serial of Cerrahpasa Medical Faculty of Istanbul University. Istanbul: Kaya Publishers, 2001: 33-47
  • Mates M, Heyd J, Soununjon M et all. The haematologist as watcdog of community health by full blood count. QJM 1995; 88: 333-339
  • Riedler GF, Zollinger P, Schmid M. Changes in the blood picture in liver diseases. Schweiz Med Wochenshr 1975; 105: 1593
  • Intragumtornchai T, Rojnukkarin Vajanamarhutue C, Israsena S. Anemias in Thai patients with cirrhosis. Int J Hematol(Ireland) 1997; 65: 365-373 P, Swasdikul D,
  • Maruyama S, Hirayama C, Yamamato et all. Red blood cell status in alcoholic and non-alcoholic liver diseases. J Lab Med 2001: 138: 332-337
  • Sherlock S, Dooley J. Alcohol and liver. In:Sherlock S, Dooley J (Editors). Diseases of the liver and biliary system. 10. baskı, Oxford: Blackwell Science Ltd, 1997: 385-400
  • Wu A, Chanarin I, Slavin G, Levi AJ. Folate deficiency in the alcoholics-its relationship to clinical and haematological abnormalities, liver disease and folate stores. Br Haematol 1975; 29: 469-478
  • Seppa K, Sillanaukee P. Women, alcohol and red cells. Alcohol Clin Exp Res. 1994: 18: 1168-1171
  • Oski FA. Anemia due to other nutritional deficiencies. In: Beutler E, Lichtman MA, Coller BS, Kipps TJ (Editors). Williams Hematology. 5. baskı, McGraw Hill Health Professions Division International Edition, 1995: 511-514
  • Balcells A, Ingelmo M, Vivancos J et all. Macrocytosis in chronic alcoholism (author’s transl). Med Clin (barc) 1979; 73 :312-314
  • Gheno G, Magnabosco V, Mazzei G. Macrocytosis and anemia in chronic alcoholism. Correlation with the results of hepatic needle biopsy. Minerva Med 1981; 72: 1301-1306
  • Yersin B, Nicolet JF, Dercy et all. Screening for excessive alcohol drinking; comparative value of carbohaydrate deficient transferin, gamma glutamyl transpeptidase and mean corpuscular volume. Arch Intern Med 1995; 155: 1907-1911
  • Sun L, Konig IR, Jacobs A, et al. Mean corpuscular volume and ADH1C genotype in white patients with alcohol-associated diseases. Alcohol Clin Exp Res 2005;29:788-93
  • Kabul Tarihi: 02.11.2007
There are 16 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Özgür Tanrıverdi This is me

Esen Ger This is me

Sernaz Uzunoğlu This is me

M. Kemal Serez This is me

B. Ümit Üre This is me

Kadir Ergen This is me

A.baki Kumbasar This is me

Publication Date February 1, 2008
Published in Issue Year 2008 Volume: 13 Issue: 1

Cite

APA Tanrıverdi, Ö., Ger, E., Uzunoğlu, S., Serez, M. K., et al. (2008). Ortalama Eritrosit Hacmi Düzeyinin Alkolik Karaciğer Sirozu Tanısındaki Yerinin Belirlenmesi ve Prognoza Etkisinin İrdelenmesi. Fırat Tıp Dergisi, 13(1), 49-52.
AMA Tanrıverdi Ö, Ger E, Uzunoğlu S, Serez MK, Üre BÜ, Ergen K, Kumbasar A. Ortalama Eritrosit Hacmi Düzeyinin Alkolik Karaciğer Sirozu Tanısındaki Yerinin Belirlenmesi ve Prognoza Etkisinin İrdelenmesi. Fırat Tıp Dergisi. February 2008;13(1):49-52.
Chicago Tanrıverdi, Özgür, Esen Ger, Sernaz Uzunoğlu, M. Kemal Serez, B. Ümit Üre, Kadir Ergen, and A.baki Kumbasar. “Ortalama Eritrosit Hacmi Düzeyinin Alkolik Karaciğer Sirozu Tanısındaki Yerinin Belirlenmesi Ve Prognoza Etkisinin İrdelenmesi”. Fırat Tıp Dergisi 13, no. 1 (February 2008): 49-52.
EndNote Tanrıverdi Ö, Ger E, Uzunoğlu S, Serez MK, Üre BÜ, Ergen K, Kumbasar A (February 1, 2008) Ortalama Eritrosit Hacmi Düzeyinin Alkolik Karaciğer Sirozu Tanısındaki Yerinin Belirlenmesi ve Prognoza Etkisinin İrdelenmesi. Fırat Tıp Dergisi 13 1 49–52.
IEEE Ö. Tanrıverdi, E. Ger, S. Uzunoğlu, M. K. Serez, B. Ü. Üre, K. Ergen, and A. Kumbasar, “Ortalama Eritrosit Hacmi Düzeyinin Alkolik Karaciğer Sirozu Tanısındaki Yerinin Belirlenmesi ve Prognoza Etkisinin İrdelenmesi”, Fırat Tıp Dergisi, vol. 13, no. 1, pp. 49–52, 2008.
ISNAD Tanrıverdi, Özgür et al. “Ortalama Eritrosit Hacmi Düzeyinin Alkolik Karaciğer Sirozu Tanısındaki Yerinin Belirlenmesi Ve Prognoza Etkisinin İrdelenmesi”. Fırat Tıp Dergisi 13/1 (February 2008), 49-52.
JAMA Tanrıverdi Ö, Ger E, Uzunoğlu S, Serez MK, Üre BÜ, Ergen K, Kumbasar A. Ortalama Eritrosit Hacmi Düzeyinin Alkolik Karaciğer Sirozu Tanısındaki Yerinin Belirlenmesi ve Prognoza Etkisinin İrdelenmesi. Fırat Tıp Dergisi. 2008;13:49–52.
MLA Tanrıverdi, Özgür et al. “Ortalama Eritrosit Hacmi Düzeyinin Alkolik Karaciğer Sirozu Tanısındaki Yerinin Belirlenmesi Ve Prognoza Etkisinin İrdelenmesi”. Fırat Tıp Dergisi, vol. 13, no. 1, 2008, pp. 49-52.
Vancouver Tanrıverdi Ö, Ger E, Uzunoğlu S, Serez MK, Üre BÜ, Ergen K, Kumbasar A. Ortalama Eritrosit Hacmi Düzeyinin Alkolik Karaciğer Sirozu Tanısındaki Yerinin Belirlenmesi ve Prognoza Etkisinin İrdelenmesi. Fırat Tıp Dergisi. 2008;13(1):49-52.