BibTex RIS Cite

An Uncommon Presentation of Chronic Lymphocytic Leukemia: Bilateral Hearing Loss

Year 2007, Volume: 12 Issue: 1, 76 - 78, 01.02.2007

Alev Akyol Erikci Ahmet Öztürk Ozkan Sayan

Abstract

Sudden sensorineural hearing loss that presents as the initial sign of haematological disease is very rare. We report a case with typical Rai Stage 2 (Binet Stage A) CLL, who presented with sudden onset deafness as the initial manifestation. A 48-year-old male presented with sudden bilateral sensorineural hearing loss. The patient was found to have chronic lymphocytic leukemia (CLL) during a work-up for his hearing loss. Early onset of sudden deafness in a CLL patient may be due to the hyperviscosity syndrome. Audiograms were recorded showing positive findings on presentation and recovery after therapy. The importance of early diagnosis and therapy is stressed in the light of this rapid clinical and audiological recovery observed here. ©2007, Firat University, Medical Faculty

Keywords

-

References

  • Lichtman MA, Rowe JM. Hyperleukocytic leukemias: Rheological, clinical, and therapeutic considerations. Blood 1982; 60: 279-283.
  • Hug V, Keating, McCredie K, Hester J, Bodey GP, Freireich EJ. Clinical course and response to treatment of patients with acute myelogenous leukemia presenting with a high leukocyte count. Cancer 1983; 53: 773-779.
  • Vernant JP, Brun B, Mannoni P, Dreyfuss B. Respiratory distress of hyperleukocytic granulocytic leukemias. Cancer 1979; 44: 264-268.
  • Onwukeme KE, Obikili AG. Blindness as a complication of chronic granulocytic leukemia. Br J Haematol 1991; 79: 120-122.
  • Williams CKO, Ogan O. Chronic myeloid leukemia associated with impairment of hearing. Br Med J 1985; 290: 1705.
  • Nageris B, Or R, Hardan I, Polliack A. Sudden onset deafness as a presenting manifestation of chronic lymphocytic leukemia. LeukLymphoma 1993; 9: 269-271.
  • Vives JF, Richard JL, Barneon G, Schved JF, Janbon C, Vallat G. Chronic lymphocytic leukaemia with cutaneous lesions and deafness following periarteritis nodosa. Sem Hop 1979; 55: 1737- 1741.
  • Gotay V. Unusual otologic manifestation of chronic lymphocytic leukemia. Laryngoscope 1976; 86: 1856-1863. 78
  • Dietrich PY, Pedraza E, Casiraghi O, Bayle C, Hayat M, Pico JL. Cardiac arrest due to leucostasis in a case of prolymphocytic leukaemia. Br J Haematol 1991; 78: 122-123.
  • McKee LC Jr, Collins RD. Intravascular leukocyte thrombi and aggregates as a cause of morbidity and mortality in leukemia. Medicine 1974; 53: 463-478.
  • Kabul Tarihi: 15.12.2006

Kronik Lenfositik Lösemide Nadir Bir Başvuru Şekli: Bilateral İşitme Kaybı

Year 2007, Volume: 12 Issue: 1, 76 - 78, 01.02.2007

Alev Akyol Erikci Ahmet Öztürk Ozkan Sayan

Abstract

Ani işitme kaybı hematolojik hastalıklarda nadiren bir başvuru belirtisi olabilir. Burada başvuru nedeni ani işitme kaybı olan Rai evre 2 (Binet evre A) olan kronik lenfositik lösemi (KLL) vakasını sunmaktayız. Kırk sekiz yaşındaki erkek hasta bilateral işitme kaybı ile başvurdu. İşitme kaybının nedeni araştırılırken KLL tespit edildi. Tedavi öncesine göre odiyogramlarında belirgin düzelme elde edildi. Ani işitme kaybı hiperlökositozun yol açtığı lökostaz ile ilişkilendirildi. İşitsel düzelimin ışığında erken tanı ve tedavinin önemi vurgulandı. ©2007, Fırat Üniversitesi, Tıp Fakültesi

Keywords

Kronik lenfositik lösemi işitme kaybı hiperviskozite

References

  • Lichtman MA, Rowe JM. Hyperleukocytic leukemias: Rheological, clinical, and therapeutic considerations. Blood 1982; 60: 279-283.
  • Hug V, Keating, McCredie K, Hester J, Bodey GP, Freireich EJ. Clinical course and response to treatment of patients with acute myelogenous leukemia presenting with a high leukocyte count. Cancer 1983; 53: 773-779.
  • Vernant JP, Brun B, Mannoni P, Dreyfuss B. Respiratory distress of hyperleukocytic granulocytic leukemias. Cancer 1979; 44: 264-268.
  • Onwukeme KE, Obikili AG. Blindness as a complication of chronic granulocytic leukemia. Br J Haematol 1991; 79: 120-122.
  • Williams CKO, Ogan O. Chronic myeloid leukemia associated with impairment of hearing. Br Med J 1985; 290: 1705.
  • Nageris B, Or R, Hardan I, Polliack A. Sudden onset deafness as a presenting manifestation of chronic lymphocytic leukemia. LeukLymphoma 1993; 9: 269-271.
  • Vives JF, Richard JL, Barneon G, Schved JF, Janbon C, Vallat G. Chronic lymphocytic leukaemia with cutaneous lesions and deafness following periarteritis nodosa. Sem Hop 1979; 55: 1737- 1741.
  • Gotay V. Unusual otologic manifestation of chronic lymphocytic leukemia. Laryngoscope 1976; 86: 1856-1863. 78
  • Dietrich PY, Pedraza E, Casiraghi O, Bayle C, Hayat M, Pico JL. Cardiac arrest due to leucostasis in a case of prolymphocytic leukaemia. Br J Haematol 1991; 78: 122-123.
  • McKee LC Jr, Collins RD. Intravascular leukocyte thrombi and aggregates as a cause of morbidity and mortality in leukemia. Medicine 1974; 53: 463-478.
  • Kabul Tarihi: 15.12.2006
There are 11 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Alev Akyol Erikci This is me

Ahmet Öztürk This is me

Ozkan Sayan This is me

Publication Date February 1, 2007
Published in Issue Year 2007 Volume: 12 Issue: 1

Cite

APA Erikci, A. A., Öztürk, A., & Sayan, O. (2007). Kronik Lenfositik Lösemide Nadir Bir Başvuru Şekli: Bilateral İşitme Kaybı. Fırat Tıp Dergisi, 12(1), 76-78.
AMA Erikci AA, Öztürk A, Sayan O. Kronik Lenfositik Lösemide Nadir Bir Başvuru Şekli: Bilateral İşitme Kaybı. Fırat Tıp Dergisi. February 2007;12(1):76-78.
Chicago Erikci, Alev Akyol, Ahmet Öztürk, and Ozkan Sayan. “Kronik Lenfositik Lösemide Nadir Bir Başvuru Şekli: Bilateral İşitme Kaybı”. Fırat Tıp Dergisi 12, no. 1 (February 2007): 76-78.
EndNote Erikci AA, Öztürk A, Sayan O (February 1, 2007) Kronik Lenfositik Lösemide Nadir Bir Başvuru Şekli: Bilateral İşitme Kaybı. Fırat Tıp Dergisi 12 1 76–78.
IEEE A. A. Erikci, A. Öztürk, and O. Sayan, “Kronik Lenfositik Lösemide Nadir Bir Başvuru Şekli: Bilateral İşitme Kaybı”, Fırat Tıp Dergisi, vol. 12, no. 1, pp. 76–78, 2007.
ISNAD Erikci, Alev Akyol et al. “Kronik Lenfositik Lösemide Nadir Bir Başvuru Şekli: Bilateral İşitme Kaybı”. Fırat Tıp Dergisi 12/1 (February 2007), 76-78.
JAMA Erikci AA, Öztürk A, Sayan O. Kronik Lenfositik Lösemide Nadir Bir Başvuru Şekli: Bilateral İşitme Kaybı. Fırat Tıp Dergisi. 2007;12:76–78.
MLA Erikci, Alev Akyol et al. “Kronik Lenfositik Lösemide Nadir Bir Başvuru Şekli: Bilateral İşitme Kaybı”. Fırat Tıp Dergisi, vol. 12, no. 1, 2007, pp. 76-78.
Vancouver Erikci AA, Öztürk A, Sayan O. Kronik Lenfositik Lösemide Nadir Bir Başvuru Şekli: Bilateral İşitme Kaybı. Fırat Tıp Dergisi. 2007;12(1):76-8.