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Relation of age, body weight and BMI with bone mineral density (BMD) at spine, proximal femur and total body BMD in postmenopausal Kashmiri women: a study of 165 cases

Year 2017, Volume: 7 Issue: 3, 246 - 253, 30.09.2017
https://doi.org/10.16899/gopctd.349944

Abstract

Aim: To find prevalence of osteoporosis and relation of age, body weight and Body Mass Index (BMI) with Bone Mineral Density (BMD) in postmenopausal Kashmiri women.

Methods: Postmenopausal women, attending the outpatient department, were registered for the study after taking a written informed consent. Age, height and weight were recorded for each subject and BMI calculated as kg/m2. BMD (t-score) was obtained at lumbar spine, proximal femur and whole body using Dual Energy X-ray Absorptiometry (DEXA). The subjects were divided into groups based on age, weight, BMI, and BMD (t-score). The results were analyzed using statistical package for social sciences. 

Results: 165 postmenopausal Kashmiri women with a mean age of 58.9 ± 9.7 years, mean weight of 56.5 ± 11.7 kg and mean BMI of 24.1 ±4.3 kg/m2 were analyzed. 96.4 %, 64.3% and 68.5 % subjects had low bone mass (osteopenia and osteoporosis) at lumbar spine, proximal femur and total body respectively. Prevalence of osteoporosis at all the sites was more in advanced age groups which was statistically significant (P < 0.05). Both body weight and BMI on a higher side had a protective influence against osteoporosis which was statistically significant (P < 0.05) except for BMI and BMD at lumbar spine (P = 0.276). Age had a negative correlation with BMD at all the measured sites (P < 0.00001) while as body weight and BMI had a positive correlation (P < 0.00001).

Conclusion: Nearly 80 % of Kashmiri postmenopausal women are osteoporotic at the lumbar spine. While as only one fourth’s are osteoporotic with respect to total body BMD and only one fifth’s with respect to proximal femur BMD. With increasing age BMD decreases at all the sites. Increase in body weight and BMI have a protective role against osteoporosis with exception of lumbar spine where BMI is not protective. Body weight is a better predictor of BMD than BMI at all the sites. 


References

  • 1. Montazerifar F, Karajibani M, Alamian S, Sandoughi M, Zakeri, Z, Dashipour AR. Age, Weight and Body Mass Index Effect on Bone Mineral Density in Postmenopausal Women. Health scope 2014;3(2):e14075.
  • 2. Lurati A, Laria A. Relationship between Lumbar Bone Mineral Density (BMD) and Body Mass Index (BMI) in Pre-Menopausal Population. A Large Cohort Study. Rheumatology (Sunnyvale) 2015;5(4):181.
  • 3. Johnell O, Kanis JA, Oden A, Johansson H, De Laet C, Delmas P. et al. Predictive value of BMD for hip and other fractures. J Bone Miner Res 2005;20(7):1185-94.
  • 4. Marshall D, Johnell O, Wedel H. Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ 1996;312(7041):1254-9.
  • 5. Kanis JA, Melton LJ, Christiansen C, Johnston CC, Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res 1994;9(8):1137-41.
  • 6. Mishra AK, Gajjar K, Patel K. Association between Body Mass Index and Bone Mineral Density among healthy women in India. Int J Med Res Health Sci 2016;5(4):156-60.
  • 7. Simon LS. Osteoporosis 2005. Clin Geriatr Med 2005;2(3)1:603-29.
  • 8. Petroudia SR, Ziaei S, Ardekani AE. Body weight is a Better Predictor of Bone Mineral Density than Body Mass Index in Postmenopausal Women. Int J Musculoskelet Pain Prevent 2016; 1(1):41-5.
  • 9. Jain V, Agrawal BK, Varshney A, Biswas SS. Prediction of bone mineral density by age, body mass index and menopausal status in middle socioeconomic status women of urban Kolar region of Bhopal. IOSR-JDMS 2013; 12(3):17-21.
  • 10. Gupta U, Sharma S, Gupta NK. Changes in Bone Mineral Density in Indian Women: A Cross-Sectional Study. Sch J App Med Sci 2014;2(3A):917-21.

Postmenopozal Kaşmirli Kadınlarda Yaş, Vücut Ağırlığı ve VKİ ile Omurga, Proksimal Femur ve Toplam Vücut Kemik Mineral Yoğunluğu (KMY) arasındaki ilişki: 165 Olgu Üzerinde Yapılan Bir Çalışma.

Year 2017, Volume: 7 Issue: 3, 246 - 253, 30.09.2017
https://doi.org/10.16899/gopctd.349944

Abstract

Amaç: Postmenapozal Kaşmirili kadınlarda osteoporoz prevalansını ve yaş, vücut ağırlığı ve Vücut Kitle İndeksi (VKİ) ile Kemik Mineral Yoğunluğu (KMY) arasındaki ilişkiyi araştırmak.

Yöntem: Poliklinik başvurusunda bulunan ve yazılı bir aydınlatılmış onam alınan Postmenopozal kadınlar çalışmaya alındı. Her bir özne için yaş, boy ve ağırlık kaydedildi ve BMI, kg / m2 olarak hesaplandı. Dual Enerji X-ray Absorptiometri (DEXA) kullanılarak lumbar omurga, proksimal femur ve tüm vücutta BMD (t-skoru) elde edildi. Olgular yaş, kilo, VKİ ve KMY'ye (t-skoru) göre gruplara ayrıldı. Sonuçlar, SPSS istatistiksel paket program kullanılarak analiz edilmiştir.

Bulgular: Ortalama yaşları 58.9 ± 9.7 yıl olan, ortalama ağırlığı 56.5 ± 11.7 kg ve ortalama BMI 24.1 ± 4.3 kg / m2 olan 165 postmenopozal Kaşmirli kadın analiz edildi. Lumbar omurga, proksimal femur ve total vücutta düşük kemik kitlesi (osteopeni ve osteoporoz) sırasıyla% 96.4,% 64.3 ve% 68.5 idi. Tüm bölgelerde osteoporoz prevalansı ileri yaş gruplarında istatistiksel olarak daha anlamlıydı (P <0.05). Hem vücut ağırlığı, hem de VKİ açısında daha yüksek bir tarafta bulunma, osteoporoza karşı koruyucu bir etkiye sahipti ki bunlar bel omurundaki VKİ ve KMY hariç istatiksel olarak anlamlıydı (p <0.05) (P = 0.276). Yaş, tüm ölçülen yerlerde KMY ile negatif korelasyon (P <0.00001), vücut ağırlığı ve VKİ ise pozitif korelasyon gösterdi (P <0.00001).

Sonuç: Kaşmirli postmenopozal kadınların yaklaşık% 80'i bel omurunda osteoporotiktir. Sadece dörtte birinin total vücut KMY'sine göre osteoporotik olduğu ve proksimal femur KMY'sine göre beşte birinin osteoporotik olduğu görülüyor. Artan yaş ile KMY tüm bölgelerde azalmaktadır. BMI'nun koruyucu olmadığı lomber omurga haricinde, vücut ağırlığındaki ve VKİ'nin osteoporoza karşı koruyucu bir rolü vardır. Vücut ağırlığı, tüm bölgelerdeki KMY açısından  VKİ'den daha iyi bir öngörücüdür.


References

  • 1. Montazerifar F, Karajibani M, Alamian S, Sandoughi M, Zakeri, Z, Dashipour AR. Age, Weight and Body Mass Index Effect on Bone Mineral Density in Postmenopausal Women. Health scope 2014;3(2):e14075.
  • 2. Lurati A, Laria A. Relationship between Lumbar Bone Mineral Density (BMD) and Body Mass Index (BMI) in Pre-Menopausal Population. A Large Cohort Study. Rheumatology (Sunnyvale) 2015;5(4):181.
  • 3. Johnell O, Kanis JA, Oden A, Johansson H, De Laet C, Delmas P. et al. Predictive value of BMD for hip and other fractures. J Bone Miner Res 2005;20(7):1185-94.
  • 4. Marshall D, Johnell O, Wedel H. Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ 1996;312(7041):1254-9.
  • 5. Kanis JA, Melton LJ, Christiansen C, Johnston CC, Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res 1994;9(8):1137-41.
  • 6. Mishra AK, Gajjar K, Patel K. Association between Body Mass Index and Bone Mineral Density among healthy women in India. Int J Med Res Health Sci 2016;5(4):156-60.
  • 7. Simon LS. Osteoporosis 2005. Clin Geriatr Med 2005;2(3)1:603-29.
  • 8. Petroudia SR, Ziaei S, Ardekani AE. Body weight is a Better Predictor of Bone Mineral Density than Body Mass Index in Postmenopausal Women. Int J Musculoskelet Pain Prevent 2016; 1(1):41-5.
  • 9. Jain V, Agrawal BK, Varshney A, Biswas SS. Prediction of bone mineral density by age, body mass index and menopausal status in middle socioeconomic status women of urban Kolar region of Bhopal. IOSR-JDMS 2013; 12(3):17-21.
  • 10. Gupta U, Sharma S, Gupta NK. Changes in Bone Mineral Density in Indian Women: A Cross-Sectional Study. Sch J App Med Sci 2014;2(3A):917-21.
There are 10 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Research
Authors

Naseer Ahmad Mir This is me

Publication Date September 30, 2017
Acceptance Date April 10, 2017
Published in Issue Year 2017 Volume: 7 Issue: 3

Cite

APA Ahmad Mir, N. (2017). Relation of age, body weight and BMI with bone mineral density (BMD) at spine, proximal femur and total body BMD in postmenopausal Kashmiri women: a study of 165 cases. Çağdaş Tıp Dergisi, 7(3), 246-253. https://doi.org/10.16899/gopctd.349944
AMA Ahmad Mir N. Relation of age, body weight and BMI with bone mineral density (BMD) at spine, proximal femur and total body BMD in postmenopausal Kashmiri women: a study of 165 cases. J Contemp Med. November 2017;7(3):246-253. doi:10.16899/gopctd.349944
Chicago Ahmad Mir, Naseer. “Relation of Age, Body Weight and BMI With Bone Mineral Density (BMD) at Spine, Proximal Femur and Total Body BMD in Postmenopausal Kashmiri Women: A Study of 165 Cases”. Çağdaş Tıp Dergisi 7, no. 3 (November 2017): 246-53. https://doi.org/10.16899/gopctd.349944.
EndNote Ahmad Mir N (November 1, 2017) Relation of age, body weight and BMI with bone mineral density (BMD) at spine, proximal femur and total body BMD in postmenopausal Kashmiri women: a study of 165 cases. Çağdaş Tıp Dergisi 7 3 246–253.
IEEE N. Ahmad Mir, “Relation of age, body weight and BMI with bone mineral density (BMD) at spine, proximal femur and total body BMD in postmenopausal Kashmiri women: a study of 165 cases”, J Contemp Med, vol. 7, no. 3, pp. 246–253, 2017, doi: 10.16899/gopctd.349944.
ISNAD Ahmad Mir, Naseer. “Relation of Age, Body Weight and BMI With Bone Mineral Density (BMD) at Spine, Proximal Femur and Total Body BMD in Postmenopausal Kashmiri Women: A Study of 165 Cases”. Çağdaş Tıp Dergisi 7/3 (November 2017), 246-253. https://doi.org/10.16899/gopctd.349944.
JAMA Ahmad Mir N. Relation of age, body weight and BMI with bone mineral density (BMD) at spine, proximal femur and total body BMD in postmenopausal Kashmiri women: a study of 165 cases. J Contemp Med. 2017;7:246–253.
MLA Ahmad Mir, Naseer. “Relation of Age, Body Weight and BMI With Bone Mineral Density (BMD) at Spine, Proximal Femur and Total Body BMD in Postmenopausal Kashmiri Women: A Study of 165 Cases”. Çağdaş Tıp Dergisi, vol. 7, no. 3, 2017, pp. 246-53, doi:10.16899/gopctd.349944.
Vancouver Ahmad Mir N. Relation of age, body weight and BMI with bone mineral density (BMD) at spine, proximal femur and total body BMD in postmenopausal Kashmiri women: a study of 165 cases. J Contemp Med. 2017;7(3):246-53.