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Frequency of adenomyosis in hysterectomy specimens performed for benign indications

Year 2012, Volume: 2 Issue: 3, 1 - 4, 01.09.2012

Abstract

Objective: The aim of this study is to determine the frequency of adenomyosis in hysterectomy specimens performed for benign indications. Methods: Adenomyosis frequency was retrospectively evaluated hystopathologically in hysterectomy specimens performed for benign indications on 149 patients between January 2009 and January 2012 in Gaziosmanpaşa University Medical School, Obstetric and Gynecology Clinic. Results: Adenomyosis frequency was determined as 11.7% (17) of 149 patients received for the elavuation for this study. There was no statistically significance in terms of ages among the cases with or without adenomyosis (49.4±8.3 vs 50.5±9.7) (p>0.05). Similarly there was no statistically significance between two groups in the number of pregnancy and parous (p>0.05). Adenomyosis was determined as 13.2% in hysterectomy specimens performed for leiomyoma and again it was determined as 17.8% in hysterectomy specimens performed for refracter menorrhagia. There was no statistically significance between two indication groups for the sake of being determined of adenomyosis hystopathologically in hysterectomy specimens (p>0.05). Conclusion: Adenomyosis can be seen in patients with leiomyoma and menorrhagia. So the possibility of adenomyosis detection should not be forgotten when the treatment is planned for the cases with leiomyoma and menorrhagia. Key words:

References

  • 1- Bird CC, McElin TW, Manalo-Estrella P. The elusive adenomyosis of the uterusdrevisited. Am J Obstet Gynecol 1972;112(5):583-93.
  • 2- Matalliotakis IM, Katsikis IK, Panidis DK. Adenomyosis: What is the impact on fertility? Curr Opin Obstet Gynecol 2005;17(3):261-64.
  • 3- Ferenczy A. Pathophysiology of adenomyosis. Hum Reprod Update 1998;4(4):312-22.
  • 4- Vercellini P, Parazzini F, Oldani S, Panazza S, Bramante T, Crosignani PG. Adenomyosis at hysterectomy: A study on frequency distribution and patient characteristics. Human Reproduction 1995;10(5):1160-2.
  • 5- Vercellini P, Vigano P, Somigliana E, Daguati R, Abbiati A, Fedele L. Adenomyosis: Epidemiological factors. Best Practice Research. Clinical Obstetrics Gynaecology 2006;20(4):465-77.
  • 6- Shaikh H, Khan KS. Adenomyosis in Pakistani women: Four year experience at the Aga Khan University Medical Centre, Karachi. Journal of Clinical Pathology 1990;43(10):817- 9.
  • 7- Bergholt T, Eriksen L, Berendt N, Jacobsen M, Hertz JB. Prevalence and risk factors of adenomyosis at hysterectomy. Human Reproduction 2001;16(11):2418-21.
  • 8- Parazzini F, Mais V, Cipriani S, Busacca M, Venturini P. Determinants of adenomyosis in women who underwent hysterectomy for benign gynecological conditions: Results from a prospective multicentric study in Italy. European Journal of Obstetrics Gynecology and Reproductive Biology 2009;143(2):103-6.
  • 9- Kavak SB. Histerektomi materyallerinde adenomyozis sıklığının araştırılması. Fırat Tıp Dergisi 2009;14(4):247- 9.
  • 10- Atılgan R, Boztosun A, Özercan MR. Histerektomi materyallerinde histopatolojik tanıların insidansı. Fırat Tıp dergisi 2012;17(1):19-22.
  • 11- Trabert B, Weiss NS, Rudra CB, Scholes D, Holt VL. A case-control investigation of adenomyosis: Impact of control group selection on risk factor strength. Women's Health Issues 2011;21(2):160-4.
  • 12- McCausland V, McCausland A. The response of adenomyosis to endometrial ablation/resection. Hum Reprod Update 1998;4(4):350-9.
  • 13- Wood C, Maher P, Hill D. Biopsy diagnosis and conservative surgical treatment of adenomyosis. Aust N Z J Obstet Gynaecol 1993;33(3):319-21.
  • 14- Sheng J, Zhang WY, Zhang JP, Lu D. The LNG-IUS study on adenomyosis: a 3-year follow-up study on the efficacy and side effects of the use of levonorgestrel intrauterine system for the treatment of dysmenorrhea associated with adenomyosis. Contraception 2009;79(3):189-93.
  • 15- Lin J, Sun C, Zheng H. Gonadotropinreleasing hormone agonists and laparoscopy in the treatment of adenomyosis and infertility. Chin Med J. 2000;113(5):442-5

Benign endikasyonlar nedeniyle uygulanan histerektomi materyallerinde adenomyozis sıklığı

Year 2012, Volume: 2 Issue: 3, 1 - 4, 01.09.2012

Abstract

AMAÇ: Bu çalışmanın amacı kliniğimizde benign endikasyonla histerektomi yapılan olgularda histerektomi materyallerinde adenomyozis sıklığının araştırılmasıdır. MATERYAL-METOD: Gaziosmanpaşa Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Kliniği'nde 2009-2012 yılları arasında benign endikasyonla histerektomi uygulanan 149 hastanın histerektomi materyallerinde histopatolojik olarak adenomyozis sıklığı retrospektif olarak araştırıldı. BULGULAR: Değerlendirmeye alınan 149 olgu içerisinde adenomyozis sıklığı %11.4 (17) olarak saptandı. Histerektomi materyalinde adenomyozis saptanan olguların yaş ortalaması ile adenomyozis saptanmayan olguların yaş ortalaması arasında fark saptanmadı (49.4±8.3 / 50.5±9.7) (p>0.05). Benzer şekilde iki grup arasında gebelik ve doğum sayıları arasında da anlamlı fark saptanmadı (p>0.05). Myom uteri nedeniyle histerektomi yapılan olguların %13.2'sinde adenomyozis saptanırken, tedaviye dirençli menometroraji nedeniyle histerektomi yapılan olguların %17.8'inde adenomyozis saptandı. Bu iki endikasyon grubu arasında histerektomi sonrası histopatolojik incelemede adenomyozis görülmesi açısından fark saptanmadı (p>0.05). SONUÇ: Adenomyozis, menorajisi olan myom uteri olgularında da görülebilmektedir. Dolayısıyla menoraji ve myom uteri birlikteliğinde tedavi planlanırken adenomyosiz olasılığının da akılda tutulmasının yararlı olacağını düşünmekteyiz.

References

  • 1- Bird CC, McElin TW, Manalo-Estrella P. The elusive adenomyosis of the uterusdrevisited. Am J Obstet Gynecol 1972;112(5):583-93.
  • 2- Matalliotakis IM, Katsikis IK, Panidis DK. Adenomyosis: What is the impact on fertility? Curr Opin Obstet Gynecol 2005;17(3):261-64.
  • 3- Ferenczy A. Pathophysiology of adenomyosis. Hum Reprod Update 1998;4(4):312-22.
  • 4- Vercellini P, Parazzini F, Oldani S, Panazza S, Bramante T, Crosignani PG. Adenomyosis at hysterectomy: A study on frequency distribution and patient characteristics. Human Reproduction 1995;10(5):1160-2.
  • 5- Vercellini P, Vigano P, Somigliana E, Daguati R, Abbiati A, Fedele L. Adenomyosis: Epidemiological factors. Best Practice Research. Clinical Obstetrics Gynaecology 2006;20(4):465-77.
  • 6- Shaikh H, Khan KS. Adenomyosis in Pakistani women: Four year experience at the Aga Khan University Medical Centre, Karachi. Journal of Clinical Pathology 1990;43(10):817- 9.
  • 7- Bergholt T, Eriksen L, Berendt N, Jacobsen M, Hertz JB. Prevalence and risk factors of adenomyosis at hysterectomy. Human Reproduction 2001;16(11):2418-21.
  • 8- Parazzini F, Mais V, Cipriani S, Busacca M, Venturini P. Determinants of adenomyosis in women who underwent hysterectomy for benign gynecological conditions: Results from a prospective multicentric study in Italy. European Journal of Obstetrics Gynecology and Reproductive Biology 2009;143(2):103-6.
  • 9- Kavak SB. Histerektomi materyallerinde adenomyozis sıklığının araştırılması. Fırat Tıp Dergisi 2009;14(4):247- 9.
  • 10- Atılgan R, Boztosun A, Özercan MR. Histerektomi materyallerinde histopatolojik tanıların insidansı. Fırat Tıp dergisi 2012;17(1):19-22.
  • 11- Trabert B, Weiss NS, Rudra CB, Scholes D, Holt VL. A case-control investigation of adenomyosis: Impact of control group selection on risk factor strength. Women's Health Issues 2011;21(2):160-4.
  • 12- McCausland V, McCausland A. The response of adenomyosis to endometrial ablation/resection. Hum Reprod Update 1998;4(4):350-9.
  • 13- Wood C, Maher P, Hill D. Biopsy diagnosis and conservative surgical treatment of adenomyosis. Aust N Z J Obstet Gynaecol 1993;33(3):319-21.
  • 14- Sheng J, Zhang WY, Zhang JP, Lu D. The LNG-IUS study on adenomyosis: a 3-year follow-up study on the efficacy and side effects of the use of levonorgestrel intrauterine system for the treatment of dysmenorrhea associated with adenomyosis. Contraception 2009;79(3):189-93.
  • 15- Lin J, Sun C, Zheng H. Gonadotropinreleasing hormone agonists and laparoscopy in the treatment of adenomyosis and infertility. Chin Med J. 2000;113(5):442-5
There are 15 citations in total.

Details

Primary Language Turkish
Journal Section Original Research
Authors

Bülent Çakmak This is me

Zeki Özsoy This is me

Mehmet Nacar This is me

Tülay Aysal This is me

Yeliz Hısım This is me

Fazlı Demirtürk This is me

Publication Date September 1, 2012
Published in Issue Year 2012 Volume: 2 Issue: 3

Cite

APA Çakmak, B., Özsoy, Z., Nacar, M., Aysal, T., et al. (2012). Benign endikasyonlar nedeniyle uygulanan histerektomi materyallerinde adenomyozis sıklığı. Çağdaş Tıp Dergisi, 2(3), 1-4.
AMA Çakmak B, Özsoy Z, Nacar M, Aysal T, Hısım Y, Demirtürk F. Benign endikasyonlar nedeniyle uygulanan histerektomi materyallerinde adenomyozis sıklığı. J Contemp Med. September 2012;2(3):1-4.
Chicago Çakmak, Bülent, Zeki Özsoy, Mehmet Nacar, Tülay Aysal, Yeliz Hısım, and Fazlı Demirtürk. “Benign Endikasyonlar Nedeniyle Uygulanan Histerektomi Materyallerinde Adenomyozis sıklığı”. Çağdaş Tıp Dergisi 2, no. 3 (September 2012): 1-4.
EndNote Çakmak B, Özsoy Z, Nacar M, Aysal T, Hısım Y, Demirtürk F (September 1, 2012) Benign endikasyonlar nedeniyle uygulanan histerektomi materyallerinde adenomyozis sıklığı. Çağdaş Tıp Dergisi 2 3 1–4.
IEEE B. Çakmak, Z. Özsoy, M. Nacar, T. Aysal, Y. Hısım, and F. Demirtürk, “Benign endikasyonlar nedeniyle uygulanan histerektomi materyallerinde adenomyozis sıklığı”, J Contemp Med, vol. 2, no. 3, pp. 1–4, 2012.
ISNAD Çakmak, Bülent et al. “Benign Endikasyonlar Nedeniyle Uygulanan Histerektomi Materyallerinde Adenomyozis sıklığı”. Çağdaş Tıp Dergisi 2/3 (September 2012), 1-4.
JAMA Çakmak B, Özsoy Z, Nacar M, Aysal T, Hısım Y, Demirtürk F. Benign endikasyonlar nedeniyle uygulanan histerektomi materyallerinde adenomyozis sıklığı. J Contemp Med. 2012;2:1–4.
MLA Çakmak, Bülent et al. “Benign Endikasyonlar Nedeniyle Uygulanan Histerektomi Materyallerinde Adenomyozis sıklığı”. Çağdaş Tıp Dergisi, vol. 2, no. 3, 2012, pp. 1-4.
Vancouver Çakmak B, Özsoy Z, Nacar M, Aysal T, Hısım Y, Demirtürk F. Benign endikasyonlar nedeniyle uygulanan histerektomi materyallerinde adenomyozis sıklığı. J Contemp Med. 2012;2(3):1-4.