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Melkersson Rosenthal syndrome: two case reports

Year 2012, Volume: 2 Issue: 1, 26 - 29, 01.03.2012

Abstract

Melkersson Rosenthal Syndrome (MRS) is a rarely seen syndrome with unknown etiology. It is described with a classic triad as recurrent facial paralysis, orofacial edema, and tongue with fissure (lingua plicata). This triad is not always being together with MRS cases. The current manuscript presents two patients one of whom had a classical triad and the other one having an orofacial edema and fissure with a history of two times facial paralysis.

References

  • Leicht S, Youngberg G, Modica L. Melkersson-Rosenthal sydrome: elevations in serum angiotensin converting enzyme and results of treatment with methotrexate. South Med J 1989;82:74-6.
  • Zimmer WM, Rogers RS, Reeve CM, et al. Orofacial
  • Rosenthal syndrome. A study of 42 patients and review of 220 cases from the literature. Oral Surg Oral Med Oral Pathol 1992;74:610-9.
  • Gerressen M, Alitreza G, Stockbrinck G, et al. Melkersson-Rosenthal syndrome: case report of a 30-year misdiagnosis. J Oral Maxillofac Surg 2005;63: 1035-9.
  • Ziem PE, Pfrommer C, Goerdt S, et al. Melkersson-Rosenthal syndrome in childhood: a challenge in differential diagnosis and treatment. Br J Dermatol 2000;143: 860-3.
  • Cockerham KP, Hidayat AA, Cockerham GC, et al. Melkersson- Rosenthal syndrome: new clinicopathologic findings in 4 cases. Arch Ophthalmol 2000;118: 227-32.
  • Smeets E, Fryns JP, Van den Berghe H. Melkersson-Rosenthal syndrome and de novo autosomal t(9;21)(p11;p11) translocation. Clin Genet 1994;45: 323-4.
  • Habel G, O’Regan B. Surgical management of macrocheilia of the lower lip. Br J Oral Maxillofac Surg 1990;28: 295-8.
  • Allen CM, Camisa C, Hamzeh S, et al. Cheilitis granulomatosa: report of six cases and review of the literature. J Am Acad Dermatol 1990;23: 444-50.
  • Worsaae N, Christensen KC, Schiodt M, et al. Melkersson-Rosenthal sydrome and cheilitis granulomatosa. A clinicopathological study of thirty-three patients with special reference to their oral lesions. Oral Surg Oral Med Oral Pathol 1982;54: 404-13.
  • Sciubba JJ, Said-Al-Naief N. Orofacial granulomatosis: presentation, pathology and management of 13 cases. J Oral Pathol Med 2003;32: 576-85.
  • Ang KL, Jones NS. Melkersson-Rosenthal syndrome. J Laryngol Otol 2002;116: 386-8.
  • Kruse-Losler B, Presser D, Metze D, et al. Surgical treatment of persistent macrocheilia in patients with Melkersson-Rosenthal syndrome and cheilitis granulomatosa. Arch Dermatol 2005;141: 1085-91.
  • Dutt SN, Mirza S, Irving RM, et al. Total decompression of facial nerve for Melkersson- Rosenthal 2000;114: 870-3. J Laryngol Otol

Melkersson Rosenthal sendromu: iki olgu sunumu

Year 2012, Volume: 2 Issue: 1, 26 - 29, 01.03.2012

Abstract

Melkersson Rosenthal Sendromu (MRS) nadir görülen etyolojisi bilinmeyen bir sendromdur. Rekürren fasiyal paralizi, orofasiyal ödem ve fissürlü dilden (lingua plicata) oluşan klasik triad ile tanımlanır. Bu triad MRS vakalarında her zaman birlikte bulunmayabilir. Makalemizde biri klasik triada sahip, diğeri daha önce iki kez fasiyal paralizi geçiren fakat kliniğimize başvurduğunda orofasiyal ödem ve fissürlü dil bulguları olan oligosemptomatik iki olgu sunulmuştur.

References

  • Leicht S, Youngberg G, Modica L. Melkersson-Rosenthal sydrome: elevations in serum angiotensin converting enzyme and results of treatment with methotrexate. South Med J 1989;82:74-6.
  • Zimmer WM, Rogers RS, Reeve CM, et al. Orofacial
  • Rosenthal syndrome. A study of 42 patients and review of 220 cases from the literature. Oral Surg Oral Med Oral Pathol 1992;74:610-9.
  • Gerressen M, Alitreza G, Stockbrinck G, et al. Melkersson-Rosenthal syndrome: case report of a 30-year misdiagnosis. J Oral Maxillofac Surg 2005;63: 1035-9.
  • Ziem PE, Pfrommer C, Goerdt S, et al. Melkersson-Rosenthal syndrome in childhood: a challenge in differential diagnosis and treatment. Br J Dermatol 2000;143: 860-3.
  • Cockerham KP, Hidayat AA, Cockerham GC, et al. Melkersson- Rosenthal syndrome: new clinicopathologic findings in 4 cases. Arch Ophthalmol 2000;118: 227-32.
  • Smeets E, Fryns JP, Van den Berghe H. Melkersson-Rosenthal syndrome and de novo autosomal t(9;21)(p11;p11) translocation. Clin Genet 1994;45: 323-4.
  • Habel G, O’Regan B. Surgical management of macrocheilia of the lower lip. Br J Oral Maxillofac Surg 1990;28: 295-8.
  • Allen CM, Camisa C, Hamzeh S, et al. Cheilitis granulomatosa: report of six cases and review of the literature. J Am Acad Dermatol 1990;23: 444-50.
  • Worsaae N, Christensen KC, Schiodt M, et al. Melkersson-Rosenthal sydrome and cheilitis granulomatosa. A clinicopathological study of thirty-three patients with special reference to their oral lesions. Oral Surg Oral Med Oral Pathol 1982;54: 404-13.
  • Sciubba JJ, Said-Al-Naief N. Orofacial granulomatosis: presentation, pathology and management of 13 cases. J Oral Pathol Med 2003;32: 576-85.
  • Ang KL, Jones NS. Melkersson-Rosenthal syndrome. J Laryngol Otol 2002;116: 386-8.
  • Kruse-Losler B, Presser D, Metze D, et al. Surgical treatment of persistent macrocheilia in patients with Melkersson-Rosenthal syndrome and cheilitis granulomatosa. Arch Dermatol 2005;141: 1085-91.
  • Dutt SN, Mirza S, Irving RM, et al. Total decompression of facial nerve for Melkersson- Rosenthal 2000;114: 870-3. J Laryngol Otol
There are 14 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Sema Koç This is me

Ahmet Eyibilen This is me

İbrahim Aladağ This is me

Levent Gürbüzler This is me

Publication Date March 1, 2012
Published in Issue Year 2012 Volume: 2 Issue: 1

Cite

APA Koç, S., Eyibilen, A., Aladağ, İ., Gürbüzler, L. (2012). Melkersson Rosenthal sendromu: iki olgu sunumu. Çağdaş Tıp Dergisi, 2(1), 26-29.
AMA Koç S, Eyibilen A, Aladağ İ, Gürbüzler L. Melkersson Rosenthal sendromu: iki olgu sunumu. J Contemp Med. March 2012;2(1):26-29.
Chicago Koç, Sema, Ahmet Eyibilen, İbrahim Aladağ, and Levent Gürbüzler. “Melkersson Rosenthal Sendromu: Iki Olgu Sunumu”. Çağdaş Tıp Dergisi 2, no. 1 (March 2012): 26-29.
EndNote Koç S, Eyibilen A, Aladağ İ, Gürbüzler L (March 1, 2012) Melkersson Rosenthal sendromu: iki olgu sunumu. Çağdaş Tıp Dergisi 2 1 26–29.
IEEE S. Koç, A. Eyibilen, İ. Aladağ, and L. Gürbüzler, “Melkersson Rosenthal sendromu: iki olgu sunumu”, J Contemp Med, vol. 2, no. 1, pp. 26–29, 2012.
ISNAD Koç, Sema et al. “Melkersson Rosenthal Sendromu: Iki Olgu Sunumu”. Çağdaş Tıp Dergisi 2/1 (March 2012), 26-29.
JAMA Koç S, Eyibilen A, Aladağ İ, Gürbüzler L. Melkersson Rosenthal sendromu: iki olgu sunumu. J Contemp Med. 2012;2:26–29.
MLA Koç, Sema et al. “Melkersson Rosenthal Sendromu: Iki Olgu Sunumu”. Çağdaş Tıp Dergisi, vol. 2, no. 1, 2012, pp. 26-29.
Vancouver Koç S, Eyibilen A, Aladağ İ, Gürbüzler L. Melkersson Rosenthal sendromu: iki olgu sunumu. J Contemp Med. 2012;2(1):26-9.