Abstract
Gastrointestinal stromal tumors are the common nonepithelial tumors in the gastrointestinal system. They are originated from gastrointestinal pacemaker cells (Cajal’s interstitial cells). Publications disclosing gastrointestinal stromal tumor’s concurrent co-occurrence with the other cancers exist in the literature. Etiology of synchronically found gastrointestinal and epithelial tumors is not known, yet there are related theories needed to be searched more. We cannot externalize a coincidental relation just because of the limited number of facts and in order to clarify this coincidence, we need further studies. A female patient who consulted to our clinic with the diagnosis of breast cancer and had an operation as a result of an intraabdominal mass fixation was presented in our study. Gastrointestinal stromal tumor’s rarely seen concurrent co-occurrence with the breast cancer was discussed clinically.
References
- 1. Miettinen M, Lasota J. Gastrointestinal stromal tumors-- definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch 2001;438(1):1-12.
- 2. Miettinen M, Sarlomo-Rikala M, Sobin LH, Lasota J. Gastrointestinal stromal tumors and leiomyosarcomas in the colon: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases. Am J Surg Pathol 2000;24(10):1339-52.
- 3. Maiorana A, Fante R, Maria Cesinaro A, Adriana Fano R. Synchronous occurrence of epithelial and stromal tumors in the stomach: a report of 6 cases. Arch Pathol Lab Med 2000;124(5):682-6.
- 4. Agaimy A, Wünsch PH, Sobin LH, Lasota J, Miettinen M. Occurrence of other malignancies in patients with gastrointestinal stromal tumors. Semin Diagn Pathol 2006;23(2):120-9.
- 5. Miettinen M, El-Rifai W, H L Sobin L, Lasota J. Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review. Hum Pathol 2002;33(5):478-83
Abstract
Gastrointestinal stromal tümörler gastrointestinal sistemin en sık görülen nonepitelyal tümörleridir. Gastrointestinal pacemaker hücrelerinden (Cajal’ın interstisyel hücreleri) köken alırlar. Literatürde gastrointestinal stromal tümörün diğer kanserler ile eş zamanlı birlikteliğini gösteren yayınlar mevcuttur. Senkron olarak bulunan gastrointestinal ve epitelyal tümörlerin etyolojisi bilinmemektedir fakat bu konu ile ilgili daha fazla araştırılması gereken teoriler vardır. Sınırlı sayıdaki olgudan rastlantısal bir ilişkiyi dışlayamayacağımızdan dolayı bu rastlantısal ilişkiyi açıklığa kavuşturmak adına ek çalışmalara ihtiyaç vardır. Çalışmamızda meme kanseri tanısı ile kliniğimize başvuran ve intraabdominal kitle tespit edilip opere edilen bir kadın hasta sunuldu. Gastrointestinal stromal tümörün meme kanseri ile eş zamanlı birlikteliğinin az görülmesi nedeniyle klinik olarak tartışıldı.
References
- 1. Miettinen M, Lasota J. Gastrointestinal stromal tumors-- definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch 2001;438(1):1-12.
- 2. Miettinen M, Sarlomo-Rikala M, Sobin LH, Lasota J. Gastrointestinal stromal tumors and leiomyosarcomas in the colon: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases. Am J Surg Pathol 2000;24(10):1339-52.
- 3. Maiorana A, Fante R, Maria Cesinaro A, Adriana Fano R. Synchronous occurrence of epithelial and stromal tumors in the stomach: a report of 6 cases. Arch Pathol Lab Med 2000;124(5):682-6.
- 4. Agaimy A, Wünsch PH, Sobin LH, Lasota J, Miettinen M. Occurrence of other malignancies in patients with gastrointestinal stromal tumors. Semin Diagn Pathol 2006;23(2):120-9.
- 5. Miettinen M, El-Rifai W, H L Sobin L, Lasota J. Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review. Hum Pathol 2002;33(5):478-83
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | July 27, 2014 |
| Published in Issue | Year 2014 Volume: 4 Issue: 1 |