A case of acute psychosis due to vitamin b12 deficiency

Year 2014, Volume: 4 Issue: 2 EK, 100 - 6, 08.09.2014

Selim Sayın Erol Arslan Şeref Demirbaş Mithat Eser Kenan Sağlam

Abstract

Patients with vitamin B12 deficiency may present with hematologic, neuropsychiatric and cardiovascular symptoms. A clinical Picture of acute psychosis can be seen in rare cases and if not corrected, vitamin B12 deficiency can lead to permanent demage. Acute psychosis and symptoms of anemia with sixty-year-old male patient was evaluated and found that vitamin B12 deficiency due to the terminal ileitis. The patient was healed without permanent damage with replacement therapy.

The diagnosis and treatment of vitamin B12 deficiency is quite simple. In order not to lead to persistent psychiatric symptoms, regardless of the presence of anemia, it would be appropriate to check blood levels of vitamin B12 in patients admitted for psychiatric problems. 

 

Keywords

Anemia, Acute psychosis, Vitamin B12 deficiency

Vitamin B12 Eksikliğine Bağlı Akut Psikoz Olgusu

Abstract

Vitamin B12 eksikliği olan olgular hematolojik, nöropsikiyatrik ve kardiyovasküler semptomlar ile başvurabilir. Akut psikoz tablosu nadiren de olsa görülebilmekte ve vitamin B12 eksikliği giderilmediğinde kalıcı hasar bırakabilir. Akut psikoz ve anemi semptomları ile kliniğimize başvuran altmış yaşında erkek hasta değerlendirildi.  Terminal ileite bağlı vitamin B12 eksikliği saptandı. Yerine koyma tedavisiyle kalıcı hasar gelişmeden hasta iyileşti.

Tanı ve tedavisi oldukça basit olan vitamin B12 eksikliğinin, kalıcı psikiyatrik sorunlara yol açmaması için psikiyatrik yakınmalarla başvuran hastalarda anemi olsun yada olmasın mutlaka vitamin B12kan düzeyinin kontrol edilmesi uygun olacaktır.

 

 

Keywords

Anemi, Akut psikoz, Vitamin B12 eksikliği

References

• -Lindenbaum J, Healton EB, Savage DG et al. Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med 1988;318(26):1720-8
• - Rajkumar AP, Jebaraj P. Chronic psychosis associated with vitamin B12 deficiency. J Assoc Physicians India. 2008;56:115-6.
• -Beck WS. Neuropsychiatric consequences of cobalamine deficiency. Adv Intern Med 1991;36:33-56
• -Holmes JM. Cerebral manifestations of vitamin-B12 deficiency. Br Med J 1956;2(5006):1394-8.
• -Bottiglieri T. Folate, vitamin B12, and neuropsychiatric disorders. Nutr Rev 1996;54(12):382-90.
• -Hutto BR. Folate and cobalamin in psychiatric illness. Compr Psychiatry 1997;38(6):305-14.
• -Mitsuyama Y, Kogoh H. Serum and cerebrospinal fluid vitamin B12 levels in demented patients with CH3-B12 treatment—preliminary study. Jpn J Psychiatry Neurol 1988;42(1):65-71.
• -Goebels N, Soyka M. Dementia associated with vitamin B (12) deficiency: presentation of two cases and review of the literature. J Neuropsychiatry Clin Neurosci 2000;12(3):389-394
• -Catalano G, Catalano MC, O’Dell KJ, Humphrey DA, Fritz EB. The utility of laboratory screening in medically III patients with pscychiatric symptoms. Ann Clin Psychiatry 2001;13(3):135-40.
• -O’Neill D, Barber RD. Reversible dementia caused by vitamin B12 deficiency. J Am Geriatr Soc 1993;41(2):192-3.