Serum Zinc, Copper and Ceruloplasmin Levels in Type 2 Diabetic Patients

Emine Şen; Bayram Şen; Özge Paşaoğlu; Müjde Aktürk; Işılay Kalan Sarı; Bülent Çelik; Hatice Pasaoglu

EN

Serum Zinc, Copper and Ceruloplasmin Levels in Type 2 Diabetic Patients

Abstract

Our objective was to investigate the possible alterations in serum zinc, copper and ceruloplasmin levels in type 2 diabetes. Fifty patients with type 2 diabetes mellitus (23 male, 27 female) who were being treated and followed by Gazi University Internal Medicine Obesity and Diabetes Clinic and 30 healthy volunteers (12 male, 18 female) were included in the study. Serum zinc and copper levels were measured by atomic absorption spectroscopy and ceruloplasmin oxidase activity was determined spectrophotometrically. While zinc levels of female diabetics were found to be significantly lower than female control group, there were no significant differences neither between male patients and male controls, nor between patient group and control group. There was no statistically significant difference in serum copper levels between patient and control groups. However, in both groups, copper levels of female subjects were found significantly higher than males. Ceruloplasmin oxidase activities were higher in patient group compared with controls and both in male and female patient groups compared with their respective controls. There was a positive correlation between serum copper and ceruloplasmin oxidase activity. These results imply that serum ceruloplasmin oxidase activity in type 2 diabetic patients and zinc levels in female type 2 diabetics show important alterations.

Keywords

Zinc, Copper, Ceruloplasmin oxidase, Type 2 Diabetes Mellitus

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Details

Primary Language

English

Subjects

Clinical Sciences

Journal Section

Research Article

Authors

Emine Şen This is me
0000-0002-4397-8952
Türkiye

Bayram Şen This is me
0000-0002-4541-881X
Türkiye

Özge Paşaoğlu This is me
Türkiye

Müjde Aktürk This is me
0000-0003-0457-6560
Türkiye

Işılay Kalan Sarı
0000-0002-8956-9505
Türkiye

Bülent Çelik
Türkiye

Hatice Pasaoglu ^*
0000-0001-8343-7432
Türkiye

Publication Date

April 30, 2021

Submission Date

March 10, 2021

Acceptance Date

March 22, 2021

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Year 2021 Volume: 3 Number: 1

IZ

https://izlik.org/JA74MB92SR

APA

Şen, E., Şen, B., Paşaoğlu, Ö., Aktürk, M., Kalan Sarı, I., Çelik, B., & Pasaoglu, H. (2021). Serum Zinc, Copper and Ceruloplasmin Levels in Type 2 Diabetic Patients. Journal of Gazi University Health Sciences Institute, 3(1), 1-9. https://izlik.org/JA74MB92SR

AMA

1.Şen E, Şen B, Paşaoğlu Ö, et al. Serum Zinc, Copper and Ceruloplasmin Levels in Type 2 Diabetic Patients. GUHES. 2021;3(1):1-9. https://izlik.org/JA74MB92SR

Chicago

Şen, Emine, Bayram Şen, Özge Paşaoğlu, et al. 2021. “Serum Zinc, Copper and Ceruloplasmin Levels in Type 2 Diabetic Patients”. Journal of Gazi University Health Sciences Institute 3 (1): 1-9. https://izlik.org/JA74MB92SR.

EndNote

Şen E, Şen B, Paşaoğlu Ö, Aktürk M, Kalan Sarı I, Çelik B, Pasaoglu H (April 1, 2021) Serum Zinc, Copper and Ceruloplasmin Levels in Type 2 Diabetic Patients. Journal of Gazi University Health Sciences Institute 3 1 1–9.

IEEE

[1]E. Şen et al., “Serum Zinc, Copper and Ceruloplasmin Levels in Type 2 Diabetic Patients”, GUHES, vol. 3, no. 1, pp. 1–9, Apr. 2021, [Online]. Available: https://izlik.org/JA74MB92SR

ISNAD

Şen, Emine - Şen, Bayram - Paşaoğlu, Özge - Aktürk, Müjde - Kalan Sarı, Işılay - Çelik, Bülent - Pasaoglu, Hatice. “Serum Zinc, Copper and Ceruloplasmin Levels in Type 2 Diabetic Patients”. Journal of Gazi University Health Sciences Institute 3/1 (April 1, 2021): 1-9. https://izlik.org/JA74MB92SR.

JAMA

1.Şen E, Şen B, Paşaoğlu Ö, Aktürk M, Kalan Sarı I, Çelik B, Pasaoglu H. Serum Zinc, Copper and Ceruloplasmin Levels in Type 2 Diabetic Patients. GUHES. 2021;3:1–9.

MLA

Şen, Emine, et al. “Serum Zinc, Copper and Ceruloplasmin Levels in Type 2 Diabetic Patients”. Journal of Gazi University Health Sciences Institute, vol. 3, no. 1, Apr. 2021, pp. 1-9, https://izlik.org/JA74MB92SR.

Vancouver

1.Emine Şen, Bayram Şen, Özge Paşaoğlu, Müjde Aktürk, Işılay Kalan Sarı, Bülent Çelik, Hatice Pasaoglu. Serum Zinc, Copper and Ceruloplasmin Levels in Type 2 Diabetic Patients. GUHES [Internet]. 2021 Apr. 1;3(1):1-9. Available from: https://izlik.org/JA74MB92SR

Abstract

Serum Zinc, Copper and Ceruloplasmin Levels in Type 2 Diabetic Patients

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