Nursing Interventions of Chemotherapyinduced peripheral neuropathy and neuropathic pain in patients receiving taxanes and platino: A literature review

Year 2013, Volume: 15 Issue: 1, 61 - 73, 01.04.2013

Kübra Saklı Ayten Demir-zencirci

Abstract

Peripheral neuropathy is one of the most common complications in the cancer treatment. Natural progression of chemotherapy- induced peripheral neuropathy deteriorates with repeating chemotherapy cures. Early diagnosis and treatment of neuropathy is very important for the life quality of patient receiving cancer treatment. However, data are very limited in this subject. Aim: The aim of this systematic review is to investigate the studies which evaluate peripheral neuropathy and neuropathic pain related with peripheral neuropathy, to determine possible nursing initiatives in this subject, and to provide basis for possible future studies. Method: Databases of Web of Knowledge and Pubmed are used for getting through journal articles related with the subject. In the queries, the keywords, “chemotherapy”, “peripheral neuropathy”, “pain”, “nursing”, “neuropathic pain”, “chemotherapy”, “oncology”, “peripheral neuropathy”, “chemotherapy”, “neuropathic pain”, “neuropathy”, and “nursing”, are used in different order. Seven articles related with chemotherapy induced peripheral neuropathy are gotten through. Results: The percentage of taxanes and platinos for causing peripheral neuropathy and neuropathic pain varies between 18% and 82%. As a result of the studies, chemotherapeutic peripheral neuropathy and neuropathic pain are found to be affecting the treatment period and casual life activities of the patients significantly. Conclusion: Fewness of the studies related with the subject and measurement devices makes performing new studies obligatory

Keywords

“chemotherapy”, “peripheral neuropathy”, “pain”, “nursing”, “neuropathic pain”

Taksan ve Platin Alan Hastalarda Periferal Nöropati ve Nöropatik Ağrıya Yönelik Hemşirelik Girişimleri: Sistematik Derleme

Abstract

Periferik nöropati kanser tedavisinin en sık görülen komplikasyonlarından biridir. Kemoterapi ilişkili periferik nöropatinin doğal seyri,tekrarlayan kemoterapi kürleri ile giderek kötüleşmektedir. Nöropatinin erken saptanması ve tedavi edilmesi, kanser tedavisi alan hastanın yaşam kalitesi için çok önemlidir. Ancak bu konuda veriler oldukça sınırlıdır. Amaç: Bu sistematik derlemenin amacı; periferal nöropati ve periferal nöropatiye ilişkin nöropatik ağrının değerlendirildiği çalışmalarınincelenmesi, bu konuda yapılabilecek hemşirelik girişimlerinin saptanması ve gelecekte yapılabilecek araştırmalara dayanak sağlanmasıdır. Yöntem: Konuyla ilgili makalelere ulaşmak için Web of Knowledge vePubmed veri tabanları kullanıldı. Taramalarda “chemotherapy”,“peripheral neuropathy”, “pain”, “nursing”, “neuropathic pain”,“chemotherapy”, “oncology”, “peripheral neuropathy”, “chemotherapy”, “neuropathic pain”, “neuropathy” ve “nursing” anahtar kelimeleri değişik sıralamalarla kullanıldı. Toplamda kemoterapi ilişkili periferal nöropati ile ilgili yedi makaleye ulaşıldı. Bulgular: Taksan ve platinin periferal nöropatiye ve nöropatik ağrıya neden olma oranları %18 ila %82 arasında değişmektedir. Çalışmalar sonucunda kemoterapötik periferal nöropati ve nöropatik ağrının hastaların tedavi sürecini ve günlük yaşam aktivitelerini önemliölçüde etkilediği bulundu.Sonuç: Konuyla ilgili çalışmaların ve ölçme araçlarının az oluşu yeni çalışmaların yapılmasını zorunlu kılmaktadır

Keywords

Kemoterapi, taksanler, platin, periferal nöropatiler, ağrı, hemşirelik

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