Glutathione in Health and Disease: A Comprehensive Review of Its Physiological Roles and Clinical Applications

Büşra Başoğlu

Glutathione in Health and Disease: A Comprehensive Review of Its Physiological Roles and Clinical Applications

Abstract

In recent years, glutathione (GSH) has been intensively researched for its potential effects in the fields of health and beauty. Glutathione is a tripeptide that performs vital functions in the body such as reducing oxidative stress, maintaining redox balance, metabolic detoxification and regulating the immune system. Suboptimal glutathione levels have been associated with various health problems such as neurodegenerative diseases, cancer and diabetes. This review addresses the biological role of glutathione and its health implications, and discusses the benefits and potential side effects of glutathione supplements in clinical situations. The synthesis of glutathione can be promoted by sulfur-rich foods and supplements can be effective in the treatment of various clinical diseases. However, it is important to take glutathione supplements in the correct dose and with the appropriate method. High doses or incorrect methods can lead to unwanted side effects. Furthermore, more reliable methods for measuring glutathione levels need to be developed. In the future, it is important to conduct more comprehensive studies to investigate the long-term effects of glutathione.

Keywords

References

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Details

Primary Language

English

Subjects

Cell Development, Proliferation and Death, Cell Metabolism, Cell Neurochemistry

Journal Section

Review Article

Authors

Büşra Başoğlu ^*
Türkiye

Publication Date

January 31, 2026

Submission Date

April 30, 2025

Acceptance Date

December 2, 2025

Published in Issue

Year 2026 Volume: 3 Number: 1

IZ

https://izlik.org/JA96WY32LD

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RIS / Bibtex

APA

Başoğlu, B. (2026). Glutathione in Health and Disease: A Comprehensive Review of Its Physiological Roles and Clinical Applications. Hitit Journal Of Science, 3(1). https://izlik.org/JA96WY32LD

AMA

1.Başoğlu B. Glutathione in Health and Disease: A Comprehensive Review of Its Physiological Roles and Clinical Applications. HJS. 2026;3(1). https://izlik.org/JA96WY32LD

Chicago

Başoğlu, Büşra. 2026. “Glutathione in Health and Disease: A Comprehensive Review of Its Physiological Roles and Clinical Applications”. Hitit Journal Of Science 3 (1). https://izlik.org/JA96WY32LD.

EndNote

Başoğlu B (January 1, 2026) Glutathione in Health and Disease: A Comprehensive Review of Its Physiological Roles and Clinical Applications. Hitit Journal Of Science 3 1

IEEE

[1]B. Başoğlu, “Glutathione in Health and Disease: A Comprehensive Review of Its Physiological Roles and Clinical Applications”, HJS, vol. 3, no. 1, Jan. 2026, [Online]. Available: https://izlik.org/JA96WY32LD

ISNAD

Başoğlu, Büşra. “Glutathione in Health and Disease: A Comprehensive Review of Its Physiological Roles and Clinical Applications”. Hitit Journal Of Science 3/1 (January 1, 2026). https://izlik.org/JA96WY32LD.

JAMA

1.Başoğlu B. Glutathione in Health and Disease: A Comprehensive Review of Its Physiological Roles and Clinical Applications. HJS. 2026;3. Available at https://izlik.org/JA96WY32LD.

MLA

Başoğlu, Büşra. “Glutathione in Health and Disease: A Comprehensive Review of Its Physiological Roles and Clinical Applications”. Hitit Journal Of Science, vol. 3, no. 1, Jan. 2026, https://izlik.org/JA96WY32LD.

Vancouver

1.Büşra Başoğlu. Glutathione in Health and Disease: A Comprehensive Review of Its Physiological Roles and Clinical Applications. HJS [Internet]. 2026 Jan. 1;3(1). Available from: https://izlik.org/JA96WY32LD