Research Article
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Assessment of Human Sperm Kinematic Parameters Using Computer-Assisted Semen Analysis

Year 2024, , 131 - 137, 30.09.2024
https://doi.org/10.17350/HJSE19030000340

Abstract

Infertility affects approximately 15% of couples trying to conceive, as reported by the World Health Organization. It is diagnosed when conception does not occur despite unprotected intercourse over the course of at least one year. The spermiogram test is a fundamental tool for identifying whether infertility originates from the male or female partner. Traditionally, sperm analysis is performed manually in reproductive clinics and laboratories, which may lead to variability in results due to subjective technician eval-uations. Recent advancements have introduced computer-assisted systems with image processing capabilities to enhance sperm quality analysis. This study presents a novel computer-assisted sperm analysis (CASA) system designed to evaluate sperm motility through digital micrographs, utilizing 14 distinct kinematic parameters. The algorithms and parameters developed offer a quantitative approach to characterizing infertility.

References

  • 1. Erdemir F, Fırat F, Gençten Y. The evaluation and clinical significance of sperm morphology. Turk Urol Sem. 2011 Jan;2:11-7.
  • 2. Cui W. Mother or nothing: the agony of infertility. World Health Organization. Bulletin of the World Health Organization. 2010 Dec 1;88(12):881.
  • 3. Gökçe A. Standard Semen Analysis Criteria of World Health Organization. Turk Urol Sem. 2011 Jan;2:1-7.
  • 4. Amann RP, Katz DF. Andrology lab corner*: Reflections on casa after 25 years. Journal of andrology. 2004 May 6;25(3):317-25.
  • 5. Katz DF, Davis RO, Delandmeter BA, Overstreet JW. Real-time analysis of sperm motion using automatic video image digitization. Computer methods and programs in biomedicine. 1985 Dec 1;21(3):173-82.
  • 6. Abbiramy VS, Shanthi V, Allidurai C. Spermatozoa detection, counting and tracking in video streams to detect asthenozoospermia. In 2010 International Conference on Signal and Image Processing 2010 Dec 15 (pp. 265-270). IEEE.
  • 7. Leung C, Lu Z, Esfandiari N, Casper RF, Sun Y. Detection and tracking of low contrast human sperm tail. In2010 IEEE International Conference on Automation Science and Engineering 2010 Aug 21 (pp. 263-268). IEEE.
  • 8. Ravanfar MR, Moradi MH. Low contrast sperm detection and tracking by watershed algorithm and particle filter. In2011 18th Iranian Conference of Biomedical Engineering (ICBME) 2011 Dec 14 (pp. 260-263). IEEE.
  • 9. Di Caprio G, El Mallahi A, Ferraro P, Dale R, Coppola G, Dale B, Coppola G, Dubois F. 4D tracking of clinical seminal samples for quantitative characterization of motility parameters. Biomedical optics express. 2014 Mar 1;5(3):690-700.
  • 10. Elsayed M, El-Sherry TM, Abdelgawad M. Development of computer-assisted sperm analysis plugin for analyzing sperm motion in microfluidic environments using Image-J. Theriogenology. 2015 Nov 1;84(8):1367-77.
  • 11. Urbano LF, Masson P, VerMilyea M, Kam M. Automatic tracking and motility analysis of human sperm in time-lapse images. IEEE transactions on medical imaging. 2016 Nov 18;36(3):792-801.
  • 12. Boumaza K, Loukil A. Computer-Assisted Analysis of Human Semen Concentration and Motility. International Journal of E-Health and Medical Communications (IJEHMC). 2020 Oct 1;11(4):17-33.
  • 13. Hernández-Ferrándiz D, Pantrigo JJ, Cabido R. SCASA: From synthetic to real computer-aided sperm analysis. InInternational Work-Conference on the Interplay Between Natural and Artificial Computation 2022 May 24 (pp. 233-242). Cham: Springer International Publishing.
  • 14. Sloter E, Schmid TE, Marchetti F, Eskenazi B, Nath J, Wyrobek AJ. Quantitative effects of male age on sperm motion. Human Reproduction. 2006 Nov 1;21(11):2868-75.
  • 15. Chenouard N, Smal I, De Chaumont F, Maška M, Sbalzarini IF, Gong Y, Cardinale J, Carthel C, Coraluppi S, Winter M, Cohen AR. Objective comparison of particle tracking methods. Nature methods. 2014 Mar;11(3):281-9.
  • 16. Yousefi J. Image binarization using Otsu thresholding algorithm. Ontario, Canada: University of Guelph. 2011 Apr 18;10.
  • 17. Suzuki S. Topological structural analysis of digitized binary images by border following. Computer vision, graphics, and image processing. 1985 Apr 1;30(1):32-46.
  • 18. World Health Organization. WHO laboratory manual for the examination and processing of human semen. World Health Organization; 2010.
  • 19. Kraemer M, Fillion C, Martin-Pont B, Auger J. Factors influencing human sperm kinematic measurements by the Celltrak computer-assisted sperm analysis system. Human reproduction (Oxford, England). 1998 Mar 1;13(3):611-9.
  • 20. Hirano Y, Shibahara H, Shimada K, Yamanaka S, Suzuki T, Takamizawa S, Motoyama M, Suzuki M. Accuracy of sperm velocity assessment using the Sperm Quality Analyzer V. Reproductive medicine and biology. 2003 Dec;2:151-7.
  • 21. Akashi T, Watanabe A, Komiya A, Fuse H. Evaluation of the sperm motility analyzer system (SMAS) for the assessment of sperm quality in infertile men. Systems biology in reproductive medicine. 2010 Dec 1;56(6):473-7.
  • 22. Mortimer ST, Swan MA. Variable kinematics of capacitating human spermatozoa. Human reproduction. 1995 Dec 1;10(12):3178-82.
  • 23. Davis RO, Katz DF. Standardization and comparability of CASA instruments. Journal of Andrology. 1992 Jan 2;13(1):81-6.
Year 2024, , 131 - 137, 30.09.2024
https://doi.org/10.17350/HJSE19030000340

Abstract

References

  • 1. Erdemir F, Fırat F, Gençten Y. The evaluation and clinical significance of sperm morphology. Turk Urol Sem. 2011 Jan;2:11-7.
  • 2. Cui W. Mother or nothing: the agony of infertility. World Health Organization. Bulletin of the World Health Organization. 2010 Dec 1;88(12):881.
  • 3. Gökçe A. Standard Semen Analysis Criteria of World Health Organization. Turk Urol Sem. 2011 Jan;2:1-7.
  • 4. Amann RP, Katz DF. Andrology lab corner*: Reflections on casa after 25 years. Journal of andrology. 2004 May 6;25(3):317-25.
  • 5. Katz DF, Davis RO, Delandmeter BA, Overstreet JW. Real-time analysis of sperm motion using automatic video image digitization. Computer methods and programs in biomedicine. 1985 Dec 1;21(3):173-82.
  • 6. Abbiramy VS, Shanthi V, Allidurai C. Spermatozoa detection, counting and tracking in video streams to detect asthenozoospermia. In 2010 International Conference on Signal and Image Processing 2010 Dec 15 (pp. 265-270). IEEE.
  • 7. Leung C, Lu Z, Esfandiari N, Casper RF, Sun Y. Detection and tracking of low contrast human sperm tail. In2010 IEEE International Conference on Automation Science and Engineering 2010 Aug 21 (pp. 263-268). IEEE.
  • 8. Ravanfar MR, Moradi MH. Low contrast sperm detection and tracking by watershed algorithm and particle filter. In2011 18th Iranian Conference of Biomedical Engineering (ICBME) 2011 Dec 14 (pp. 260-263). IEEE.
  • 9. Di Caprio G, El Mallahi A, Ferraro P, Dale R, Coppola G, Dale B, Coppola G, Dubois F. 4D tracking of clinical seminal samples for quantitative characterization of motility parameters. Biomedical optics express. 2014 Mar 1;5(3):690-700.
  • 10. Elsayed M, El-Sherry TM, Abdelgawad M. Development of computer-assisted sperm analysis plugin for analyzing sperm motion in microfluidic environments using Image-J. Theriogenology. 2015 Nov 1;84(8):1367-77.
  • 11. Urbano LF, Masson P, VerMilyea M, Kam M. Automatic tracking and motility analysis of human sperm in time-lapse images. IEEE transactions on medical imaging. 2016 Nov 18;36(3):792-801.
  • 12. Boumaza K, Loukil A. Computer-Assisted Analysis of Human Semen Concentration and Motility. International Journal of E-Health and Medical Communications (IJEHMC). 2020 Oct 1;11(4):17-33.
  • 13. Hernández-Ferrándiz D, Pantrigo JJ, Cabido R. SCASA: From synthetic to real computer-aided sperm analysis. InInternational Work-Conference on the Interplay Between Natural and Artificial Computation 2022 May 24 (pp. 233-242). Cham: Springer International Publishing.
  • 14. Sloter E, Schmid TE, Marchetti F, Eskenazi B, Nath J, Wyrobek AJ. Quantitative effects of male age on sperm motion. Human Reproduction. 2006 Nov 1;21(11):2868-75.
  • 15. Chenouard N, Smal I, De Chaumont F, Maška M, Sbalzarini IF, Gong Y, Cardinale J, Carthel C, Coraluppi S, Winter M, Cohen AR. Objective comparison of particle tracking methods. Nature methods. 2014 Mar;11(3):281-9.
  • 16. Yousefi J. Image binarization using Otsu thresholding algorithm. Ontario, Canada: University of Guelph. 2011 Apr 18;10.
  • 17. Suzuki S. Topological structural analysis of digitized binary images by border following. Computer vision, graphics, and image processing. 1985 Apr 1;30(1):32-46.
  • 18. World Health Organization. WHO laboratory manual for the examination and processing of human semen. World Health Organization; 2010.
  • 19. Kraemer M, Fillion C, Martin-Pont B, Auger J. Factors influencing human sperm kinematic measurements by the Celltrak computer-assisted sperm analysis system. Human reproduction (Oxford, England). 1998 Mar 1;13(3):611-9.
  • 20. Hirano Y, Shibahara H, Shimada K, Yamanaka S, Suzuki T, Takamizawa S, Motoyama M, Suzuki M. Accuracy of sperm velocity assessment using the Sperm Quality Analyzer V. Reproductive medicine and biology. 2003 Dec;2:151-7.
  • 21. Akashi T, Watanabe A, Komiya A, Fuse H. Evaluation of the sperm motility analyzer system (SMAS) for the assessment of sperm quality in infertile men. Systems biology in reproductive medicine. 2010 Dec 1;56(6):473-7.
  • 22. Mortimer ST, Swan MA. Variable kinematics of capacitating human spermatozoa. Human reproduction. 1995 Dec 1;10(12):3178-82.
  • 23. Davis RO, Katz DF. Standardization and comparability of CASA instruments. Journal of Andrology. 1992 Jan 2;13(1):81-6.
There are 23 citations in total.

Details

Primary Language English
Subjects Engineering
Journal Section Research Articles
Authors

Nazlı Irmak Karaark This is me

Hüseyin Kurtuldu 0000-0003-0876-4999

Publication Date September 30, 2024
Submission Date August 9, 2022
Published in Issue Year 2024

Cite

Vancouver Karaark NI, Kurtuldu H. Assessment of Human Sperm Kinematic Parameters Using Computer-Assisted Semen Analysis. Hittite J Sci Eng. 2024;11(3):131-7.

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