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Year 2019, , 173 - 177, 30.09.2019
https://doi.org/10.17350/HJSE19030000144

Abstract

References

  • 1. INC, International Nut and Dried Fruit Council. Nuts and Dried Fruits Statistical yearbook 2017/2018 (2017). https://www. nutfruit.org/files/tech/1524481168_INC_Statistical_ Yearbook_2017-2018.pdf Access date 24.07.2018
  • 2. Scott, PM, Trucksess, MW. Prevention of mycotoxins in dried fruit, other fruit products, and botanicals, in: Appell, M, Kendra, D F, Trucksess, MW (Eds.). Mycotoxin prevention and control in agriculture. ACS Symposium Series, Washington DC. 1031 pp. 17–35, 2009.
  • 3. Richard, JL. Some major mycotoxins and their mycotoxicoses-An overview. International J Food Microbiol 119 (1–2) (2007) 3–10.
  • 4. IARC, International Agency for Research on Cancer. Some naturally occuring substances: Food items and constituents, heterocyclic aromatic amines and mycotoxins. IARC monographs on the evaluation of carcinogenic risks of chemicals to humans vol 56 Lyon, France, 1993 https:// monographs.iarc.fr/wp-content/uploads/2018/06/ mono56.pdf Access date 24.07.2018
  • 5. EFSA (European Food Safety Authority). Opinion of the Scientific Panel on Contaminants in the Food chain on a request from the European Commission related to the potential increase of consumer health risk by a possibleof the existing maximum levels for aflatoxins in almonds, hazelnuts and pistachios and derived products. The EFSA Journal 446 (2007) 1-127.
  • 6. JECFA. Evaluations of Certain Food Additives and Contaminants. WHO Food additives Series, vol. 40. (1998) IPCS, WHO, Geneva, Switzerland
  • 7. JECFA. Evaluation of certain food additives and contaminants. Forty-ninth Report. Technical Report Series No. 884. Geneva: WHO. (1999) pp 69–77.
  • 8. Liu Y, Wu F. Global burden of aflatoxin-induced hepatocellular carcinoma: A risk assessment. Environmental Health Perspective 118 (6) (2010) 818–824.
  • 9. Scientific Committee for Food (SCF). European Commission DG XXIV Unit B3. Thirty-fifth Report. Opinion on aflatoxins B1, B2, G1, G2, M1 and patulin. Expressed on 23 September 1994.
  • 10. U.S. Food and Drug Administration (FDA). Guidance for Industry: action levels for poisonous or deleterious substances in human food and animal feed. (2000) Available at: https:// www.fda.gov/Food/GuidanceRegulation/GuidanceDocuments RegulatoryInformation/ChemicalContaminantsMetalsNatural ToxinsPesticides/ucm077969.htm#afla Access: 14/11/18
  • 11. Codex Alimentarius Commission (CAC). Report of the sixth session of the Codex Committee on Contaminants in Foods, 35th session. July 2-7, 2012. (2012) FAO, Rome, Italy. Available at: http://www.fao.org/tempref/codex/Reports/ Reports_2012/REP12_CFe.pdf Access Date 14/11/2018
  • 12. Wang X, Lien K, Ling M. Probabilistic health risk assessment for dietary exposure to aflatoxin in peanut and peanut products in Taiwan. Food Control 91 (2018) 372-380
  • 13. Huong BTM, Tuyen LD, Do TT, Madsen H, Brimer L, Dalsgaard A. Afltoxins and fumonisins in rice and maize staple cereals in Northern Vietnam and dietary exposure in different ethnic groups. Food Control 70 (2016) 191-200.
  • 14. Raad F, Nasreddine L, Hilan C, Bartosik M, Parent-Massin D. Dietary exposure to aflatoxins, ochratoxin A and deoxynivalenol from a total diet study in an adult urban Lebanese population. Food and Chemical Toxicology 73 (2014) 35-43.
  • 15. AOAC Official Method 999.07. Aflatoxins and total aflatoxins in peanut butter, pistachio paste, fig paste and paprika powder. Immunoaffinity column-liquid chromatography with post-column derivatization. Journal of AOAC International 83 (2000) 320.
  • 16. TUIK, National Institute of Statistics of Turkey (2016) www. tuik.gov.tr Access Date 14/11/2018
  • 17. EFSA. Management of left-censored data in dietary exposure assessment of chemical substances. European Food Safety Authority Journal 8 (2010) 1557.
  • 18. Mehmet D, Meliksah E, Serif Y, Gunay S, Tuncer O, Zeynep S. Prevalence of Hepatitis B Infection in the Southeastern Region of Turkey: Comparison of Risk factors for HBV Infection in Rural and Urban Areas. Japanese Journal of Infectious Diseases, 58 (2005) 15-19
  • 19. Mimoune NA, Arroyo-Manzares N, Gamiz-Gracia L, GarciaCampana AM, Bouti K, Sabaou N, Riba A. Aspergillus section Flavi and aflatoxins in dried figs and nuts in Algeria. Food Additives and Contaminants B 11 (2) (2018) 119-125
  • 20. Iqbal SZ, Mehmood Z, Asi MR, Shahid M, Sehar M, Malik N. Cooccurrence of aflatoxins and ochratoxin A in nuts, dry fruits, and nuty products. Journal of Food Safety 38 (4) (2018) 1-7
  • 21. Heshmati A, Zohrevand T, Khaneghah AM, Nejad ASM, Sant’Ana AS. Co-occurrence of aflatoxins and ochratoxin A in dried fruits in Iran: Dietary exposure risk assessment. Food and Chemical Toxicology 106 (2017) 202-208
  • 22. Kabak B. Aflatoxins in hazelnuts and dried figs: Occurrence and exposure assessment. Food Chemistry 211 (2016) 8-16.
  • 23. Bircan C, Koç M. Aflatoxins in Dried Figs in Turkey: A Comparative Survey on the Exported and Locally Consumed Dried Figs for Assessment of Exposure. Journal of Agricultural Science and Technology 14 (2012) 1265-1274.
  • 24. Heperkan D, Karbancioglu Güler F, Oktay HI. Mycoflora and natural occurence of aflatoxin, cyclopiazonic acid, fumonisin and ochratoxin A in dried figs. Food Additives and Contaminants A 29 (2)(2012) 277-286.
  • 25. Bircan C, Barringer SA, Ulken U, Pehlivan R. Aflatoxin levels in dried figs, nuts and paprika for export from Turkey. International Journal of Food Science and Technology 43 (2008) 1492-1498
  • 26. Kilonzo RM, Imungi JK, Muiru WM, Lamuka PO, Kamau Njage PM. Household dietary exposure to aflatoxins from maize and maize products in Kenya. Food Additives and Contaminants A 31 (2014) 2055-2062.
  • 27. Türkiye Cumhuriyeti Sağlık Bakanlığı Sağlık Araştırmaları Genel Müdürlüğü, Türkiye beslenme ve sağlık araştırması 2010, Beslenme durumu ve alışkanlıklarının değerlendirilmesi sonuç raporu (2014). Hacettepe Üniversitesi Beslenme ve Diyetetik Bölümü. Available at: https://www.tuseb.gov.tr/enstitu/tacese/yuklemeler/ ekitap/Beslenme/ tbsa_beslenme_arastirmasi_sonuc_raporu.pdf Access Date 30/07/2019

Dietary Exposure Assessment of Aflatoxin From Dried Figs in Turkey

Year 2019, , 173 - 177, 30.09.2019
https://doi.org/10.17350/HJSE19030000144

Abstract

Aflatoxins are fungi’s secondary toxigenic metabolites and known as potent hepatocarcinogen for humans. The purpose of the present study is to assess health risk for Turkish adult population posing by dried fig consumption due to the aflatoxin contamination. In order to make this evaluation total of 23.547 aflatoxin monitoring data of dried figs from the Turkish Ministry of Food, Agriculture and Livestock between the crop years of 2011/2012-2015/2016 in Turkey were used. Intakes were estimated using consumption data and aflatoxin concentrations and expressed using the average Turkish adults’ body weight 72.8 kg . Estimated daily exposure was found 0.005 ng/kg bw/day for aflatoxin B1 , 0.009 for total aflatoxins in a worst case scenario. The calculated margin of exposure MOE was higher than the 10.000. Cancer risk in Turkish adult population observed in the range between 0.00017 to 0.00030 cancers per 100,000 people per year. Calculated MOE and population risk according to estimated daily intake revealed that Turkish adult population are not under the toxicological risk through dried fig consumption.

References

  • 1. INC, International Nut and Dried Fruit Council. Nuts and Dried Fruits Statistical yearbook 2017/2018 (2017). https://www. nutfruit.org/files/tech/1524481168_INC_Statistical_ Yearbook_2017-2018.pdf Access date 24.07.2018
  • 2. Scott, PM, Trucksess, MW. Prevention of mycotoxins in dried fruit, other fruit products, and botanicals, in: Appell, M, Kendra, D F, Trucksess, MW (Eds.). Mycotoxin prevention and control in agriculture. ACS Symposium Series, Washington DC. 1031 pp. 17–35, 2009.
  • 3. Richard, JL. Some major mycotoxins and their mycotoxicoses-An overview. International J Food Microbiol 119 (1–2) (2007) 3–10.
  • 4. IARC, International Agency for Research on Cancer. Some naturally occuring substances: Food items and constituents, heterocyclic aromatic amines and mycotoxins. IARC monographs on the evaluation of carcinogenic risks of chemicals to humans vol 56 Lyon, France, 1993 https:// monographs.iarc.fr/wp-content/uploads/2018/06/ mono56.pdf Access date 24.07.2018
  • 5. EFSA (European Food Safety Authority). Opinion of the Scientific Panel on Contaminants in the Food chain on a request from the European Commission related to the potential increase of consumer health risk by a possibleof the existing maximum levels for aflatoxins in almonds, hazelnuts and pistachios and derived products. The EFSA Journal 446 (2007) 1-127.
  • 6. JECFA. Evaluations of Certain Food Additives and Contaminants. WHO Food additives Series, vol. 40. (1998) IPCS, WHO, Geneva, Switzerland
  • 7. JECFA. Evaluation of certain food additives and contaminants. Forty-ninth Report. Technical Report Series No. 884. Geneva: WHO. (1999) pp 69–77.
  • 8. Liu Y, Wu F. Global burden of aflatoxin-induced hepatocellular carcinoma: A risk assessment. Environmental Health Perspective 118 (6) (2010) 818–824.
  • 9. Scientific Committee for Food (SCF). European Commission DG XXIV Unit B3. Thirty-fifth Report. Opinion on aflatoxins B1, B2, G1, G2, M1 and patulin. Expressed on 23 September 1994.
  • 10. U.S. Food and Drug Administration (FDA). Guidance for Industry: action levels for poisonous or deleterious substances in human food and animal feed. (2000) Available at: https:// www.fda.gov/Food/GuidanceRegulation/GuidanceDocuments RegulatoryInformation/ChemicalContaminantsMetalsNatural ToxinsPesticides/ucm077969.htm#afla Access: 14/11/18
  • 11. Codex Alimentarius Commission (CAC). Report of the sixth session of the Codex Committee on Contaminants in Foods, 35th session. July 2-7, 2012. (2012) FAO, Rome, Italy. Available at: http://www.fao.org/tempref/codex/Reports/ Reports_2012/REP12_CFe.pdf Access Date 14/11/2018
  • 12. Wang X, Lien K, Ling M. Probabilistic health risk assessment for dietary exposure to aflatoxin in peanut and peanut products in Taiwan. Food Control 91 (2018) 372-380
  • 13. Huong BTM, Tuyen LD, Do TT, Madsen H, Brimer L, Dalsgaard A. Afltoxins and fumonisins in rice and maize staple cereals in Northern Vietnam and dietary exposure in different ethnic groups. Food Control 70 (2016) 191-200.
  • 14. Raad F, Nasreddine L, Hilan C, Bartosik M, Parent-Massin D. Dietary exposure to aflatoxins, ochratoxin A and deoxynivalenol from a total diet study in an adult urban Lebanese population. Food and Chemical Toxicology 73 (2014) 35-43.
  • 15. AOAC Official Method 999.07. Aflatoxins and total aflatoxins in peanut butter, pistachio paste, fig paste and paprika powder. Immunoaffinity column-liquid chromatography with post-column derivatization. Journal of AOAC International 83 (2000) 320.
  • 16. TUIK, National Institute of Statistics of Turkey (2016) www. tuik.gov.tr Access Date 14/11/2018
  • 17. EFSA. Management of left-censored data in dietary exposure assessment of chemical substances. European Food Safety Authority Journal 8 (2010) 1557.
  • 18. Mehmet D, Meliksah E, Serif Y, Gunay S, Tuncer O, Zeynep S. Prevalence of Hepatitis B Infection in the Southeastern Region of Turkey: Comparison of Risk factors for HBV Infection in Rural and Urban Areas. Japanese Journal of Infectious Diseases, 58 (2005) 15-19
  • 19. Mimoune NA, Arroyo-Manzares N, Gamiz-Gracia L, GarciaCampana AM, Bouti K, Sabaou N, Riba A. Aspergillus section Flavi and aflatoxins in dried figs and nuts in Algeria. Food Additives and Contaminants B 11 (2) (2018) 119-125
  • 20. Iqbal SZ, Mehmood Z, Asi MR, Shahid M, Sehar M, Malik N. Cooccurrence of aflatoxins and ochratoxin A in nuts, dry fruits, and nuty products. Journal of Food Safety 38 (4) (2018) 1-7
  • 21. Heshmati A, Zohrevand T, Khaneghah AM, Nejad ASM, Sant’Ana AS. Co-occurrence of aflatoxins and ochratoxin A in dried fruits in Iran: Dietary exposure risk assessment. Food and Chemical Toxicology 106 (2017) 202-208
  • 22. Kabak B. Aflatoxins in hazelnuts and dried figs: Occurrence and exposure assessment. Food Chemistry 211 (2016) 8-16.
  • 23. Bircan C, Koç M. Aflatoxins in Dried Figs in Turkey: A Comparative Survey on the Exported and Locally Consumed Dried Figs for Assessment of Exposure. Journal of Agricultural Science and Technology 14 (2012) 1265-1274.
  • 24. Heperkan D, Karbancioglu Güler F, Oktay HI. Mycoflora and natural occurence of aflatoxin, cyclopiazonic acid, fumonisin and ochratoxin A in dried figs. Food Additives and Contaminants A 29 (2)(2012) 277-286.
  • 25. Bircan C, Barringer SA, Ulken U, Pehlivan R. Aflatoxin levels in dried figs, nuts and paprika for export from Turkey. International Journal of Food Science and Technology 43 (2008) 1492-1498
  • 26. Kilonzo RM, Imungi JK, Muiru WM, Lamuka PO, Kamau Njage PM. Household dietary exposure to aflatoxins from maize and maize products in Kenya. Food Additives and Contaminants A 31 (2014) 2055-2062.
  • 27. Türkiye Cumhuriyeti Sağlık Bakanlığı Sağlık Araştırmaları Genel Müdürlüğü, Türkiye beslenme ve sağlık araştırması 2010, Beslenme durumu ve alışkanlıklarının değerlendirilmesi sonuç raporu (2014). Hacettepe Üniversitesi Beslenme ve Diyetetik Bölümü. Available at: https://www.tuseb.gov.tr/enstitu/tacese/yuklemeler/ ekitap/Beslenme/ tbsa_beslenme_arastirmasi_sonuc_raporu.pdf Access Date 30/07/2019
There are 27 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Hatice Imge Oktay Basegmez This is me

Publication Date September 30, 2019
Published in Issue Year 2019

Cite

Vancouver Basegmez HIO. Dietary Exposure Assessment of Aflatoxin From Dried Figs in Turkey. Hittite J Sci Eng. 2019;6(3):173-7.

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