Year 2017, Volume 4 , Issue 2, Pages 91 - 97 2017-09-01

DNA-Binding Properties of Nickle II Phthalocyanine with 2-Isopropyl-5-Methylphenoxy Substituents and Their Studies of UV/Vis, Fluorescence Spectroscopies, Cyclic voltametry, Gel Eelectrophoresis and Viscosity Measurement

Ali ARSLANTAS [1] , Mehmet Salih AGİRTAS [2]


I n this study, previously synthesized Ni II phthalocyanine compound bearing 2,10,16,24-tetrakis 2-isopropyl-5-methylphenoxy group was chosen for its interaction with calf thymus-DNA. Calf thymus-DNA was used to determine DNA binding properties of Ni II phthalocyanine compound. The DNA binding activities of Ni II phthalocyanine compound bearing 2-isopropyl-5-methylphenoxy substituent was investigated by using absorption titration, fluorescence emission, cyclic voltammetry, gel elctrophoresis in Tris-HCl buffer at pH 7.0. In addition to above methods, melting point and viscosity experiment were performed to determine the DNA intercation of the compound in Tris-HCl buffer solution. The results showed that Ni II phthalocyanine compound binds strongly to calf thymus-DNA via intercalation binding
Uv-Vis spectroscopy, DNA binding, phthalocyanines, cyclic voltametry, electrophoresis
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Primary Language en
Journal Section Research Article
Authors

Author: Ali ARSLANTAS
Institution: Karabuk University, Department of Biomedical Engineering, Karabuk, Turkey

Author: Mehmet Salih AGİRTAS
Institution: Yüzüncü Yıl University, Department of Chemistry, Van, Turkey

Dates

Application Date : May 7, 2021
Acceptance Date : May 7, 2021
Publication Date : September 1, 2017

Bibtex @ { hjse859980, journal = {Hittite Journal of Science and Engineering}, issn = {}, eissn = {2148-4171}, address = {Hitit Üniversitesi Mühendislik Fakültesi Kuzey Kampüsü Çevre Yolu Bulvarı 19030 Çorum / TÜRKİYE}, publisher = {Hitit University}, year = {2017}, volume = {4}, pages = {91 - 97}, doi = {10.17350/HJSE19030000054}, title = {DNA-Binding Properties of Nickle II Phthalocyanine with 2-Isopropyl-5-Methylphenoxy Substituents and Their Studies of UV/Vis, Fluorescence Spectroscopies, Cyclic voltametry, Gel Eelectrophoresis and Viscosity Measurement}, key = {cite}, author = {Arslantas, Ali and Agirtas, Mehmet Salih} }
APA Arslantas, A , Agirtas, M . (2017). DNA-Binding Properties of Nickle II Phthalocyanine with 2-Isopropyl-5-Methylphenoxy Substituents and Their Studies of UV/Vis, Fluorescence Spectroscopies, Cyclic voltametry, Gel Eelectrophoresis and Viscosity Measurement . Hittite Journal of Science and Engineering , 4 (2) , 91-97 . DOI: 10.17350/HJSE19030000054
MLA Arslantas, A , Agirtas, M . "DNA-Binding Properties of Nickle II Phthalocyanine with 2-Isopropyl-5-Methylphenoxy Substituents and Their Studies of UV/Vis, Fluorescence Spectroscopies, Cyclic voltametry, Gel Eelectrophoresis and Viscosity Measurement" . Hittite Journal of Science and Engineering 4 (2017 ): 91-97 <https://dergipark.org.tr/en/pub/hjse/issue/59666/859980>
Chicago Arslantas, A , Agirtas, M . "DNA-Binding Properties of Nickle II Phthalocyanine with 2-Isopropyl-5-Methylphenoxy Substituents and Their Studies of UV/Vis, Fluorescence Spectroscopies, Cyclic voltametry, Gel Eelectrophoresis and Viscosity Measurement". Hittite Journal of Science and Engineering 4 (2017 ): 91-97
RIS TY - JOUR T1 - DNA-Binding Properties of Nickle II Phthalocyanine with 2-Isopropyl-5-Methylphenoxy Substituents and Their Studies of UV/Vis, Fluorescence Spectroscopies, Cyclic voltametry, Gel Eelectrophoresis and Viscosity Measurement AU - Ali Arslantas , Mehmet Salih Agirtas Y1 - 2017 PY - 2017 N1 - doi: 10.17350/HJSE19030000054 DO - 10.17350/HJSE19030000054 T2 - Hittite Journal of Science and Engineering JF - Journal JO - JOR SP - 91 EP - 97 VL - 4 IS - 2 SN - -2148-4171 M3 - doi: 10.17350/HJSE19030000054 UR - https://doi.org/10.17350/HJSE19030000054 Y2 - 2021 ER -
EndNote %0 Hittite Journal of Science and Engineering DNA-Binding Properties of Nickle II Phthalocyanine with 2-Isopropyl-5-Methylphenoxy Substituents and Their Studies of UV/Vis, Fluorescence Spectroscopies, Cyclic voltametry, Gel Eelectrophoresis and Viscosity Measurement %A Ali Arslantas , Mehmet Salih Agirtas %T DNA-Binding Properties of Nickle II Phthalocyanine with 2-Isopropyl-5-Methylphenoxy Substituents and Their Studies of UV/Vis, Fluorescence Spectroscopies, Cyclic voltametry, Gel Eelectrophoresis and Viscosity Measurement %D 2017 %J Hittite Journal of Science and Engineering %P -2148-4171 %V 4 %N 2 %R doi: 10.17350/HJSE19030000054 %U 10.17350/HJSE19030000054
ISNAD Arslantas, Ali , Agirtas, Mehmet Salih . "DNA-Binding Properties of Nickle II Phthalocyanine with 2-Isopropyl-5-Methylphenoxy Substituents and Their Studies of UV/Vis, Fluorescence Spectroscopies, Cyclic voltametry, Gel Eelectrophoresis and Viscosity Measurement". Hittite Journal of Science and Engineering 4 / 2 (September 2017): 91-97 . https://doi.org/10.17350/HJSE19030000054
AMA Arslantas A , Agirtas M . DNA-Binding Properties of Nickle II Phthalocyanine with 2-Isopropyl-5-Methylphenoxy Substituents and Their Studies of UV/Vis, Fluorescence Spectroscopies, Cyclic voltametry, Gel Eelectrophoresis and Viscosity Measurement. Hittite J Sci Eng. 2017; 4(2): 91-97.
Vancouver Arslantas A , Agirtas M . DNA-Binding Properties of Nickle II Phthalocyanine with 2-Isopropyl-5-Methylphenoxy Substituents and Their Studies of UV/Vis, Fluorescence Spectroscopies, Cyclic voltametry, Gel Eelectrophoresis and Viscosity Measurement. Hittite Journal of Science and Engineering. 2017; 4(2): 91-97.
IEEE A. Arslantas and M. Agirtas , "DNA-Binding Properties of Nickle II Phthalocyanine with 2-Isopropyl-5-Methylphenoxy Substituents and Their Studies of UV/Vis, Fluorescence Spectroscopies, Cyclic voltametry, Gel Eelectrophoresis and Viscosity Measurement", Hittite Journal of Science and Engineering, vol. 4, no. 2, pp. 91-97, Sep. 2017, doi:10.17350/HJSE19030000054