Determination and Speciation of Selenium in Pharmaceutical Samples, Spiked Veterinary Drug Samples with a Kinetic Catalytic Method

Year 2023, Volume: 10 Issue: 2, 185 - 191, 30.06.2023

Esra Bağda

https://doi.org/10.17350/HJSE19030000296

Abstract

In the present study a new kinetic catalytic method was developed for the sensitive determination of selenium in pharmaceutical formulations. The reaction between basic blue 3 (BB3) and sulphide catalysed by Se (IV) in the presence of acetic-phosphoric-boric acid buffer system. The decrease in the absorbance at 654 nm indicated the reduction of BB3. The presence of selenium (IV) accelerated the reaction rate. The method based on the linear correlation between amount of Se(IV) and reaction rate. Under optimum conditions, the linear calibration range was found as 0.1-2.0 µg ml-1 by the fixed time method for the 0.5-5 min. The tolerance limits of various species was also studied. The interfering effect of some cations such as Cr3+, Fe3+, and Hg2+ was reduced with using cation exchange resin. The proposed method was successfully applied to spiked nasal spray and veterinary drug samples. Besides, total selenium, Se (IV) and Se (VI) speciation also conducted with reducing Se (VI) to Se (IV) with HCl in the synthetic mixtures.

Keywords

Selenium, pharmaceutical samples, veterinary drug

References

• 1. Miletić D, Turło J, Podsadni P, Pantić M, Nedović V, Lević S, & Nikšić M. Selenium‐enriched Coriolus versicolor mushroom biomass: potential novel food supplement with improved selenium bioavailability. J Sci Food Agric. 2019; 99(11):5122-5130.
• 2. Tolu J, Bouchet S, Helfenstein J, Hausheer O, ChékifiS, Frossard E, Tamburini F, Chadwick OA, Winkel LH. Understanding soil selenium accumulation and bioavailability through size resolved and elemental characterization of soil extracts. Nat Commun. 2022; 13(1):1-16.
• 3. Amin N, Afkhami A, Madrakian T. Construction of a novel" Off- On" fluorescence sensor for highly selective sensing of selenite based on europium ions induced crosslinking of nitrogen-doped carbon dots. J Lumin. 2018; 194:768-777.
• 4. Brusa L, Tudino M, Schlotthauer J, Sigrist M. Selenium speciation in soils using flow injection hydride generation atomic absorption spectrometry with on-line removal of organic matter interferences. Talanta. 2023; 253:123898.
• 5. Gómez-Nieto B, Gismera MJ, Sevilla MT, Procopio JR. Direct solid sampling of biological species for the rapid determination of selenium by high-resolution continuum source graphite furnace atomic absorption spectrometry. Anal Chim Acta. 2022; 1202:339637.
• 6. Lashari AA, Kazi TG, Baig JA, Afridi HI, Memon AA. Speciation of the Selenium in Groundwater Samples of Different Aquifers from Coal Mining Fields: Applied a Green Analytical Technique. Water Air Soil Pollut. 2022; 233(11):1-11.
• 7. Souza SO, Ávila DVL, Cerdà V, Araujo RGO. Selenium inorganic speciation in beers using MSFIA-HG-AFS system after multivariate optimization. Food Chem. 2022; 367:130673.
• 8. Merino IE, Stegmann E, Aliaga ME, Gomez M, Arancibia V, Rojas C. Determination of Se (IV) concentration via cathodic stripping voltammetry in the presence of Cu (II) ions and ammonium diethyl dithiophosphate. Anal Chim Acta. 2019; 1048:22-30.
• 9. Stoica A, Babaua GR, Iorgulescu EE, Marinescu D, Baiulescu GE. Differential pulse cathodic stripping voltammetric determination of selenium in pharmaceutical products. J Pharm Biomed Anal. 2002; 30(4):1425-1429.
• 10. Martins FCOL, De Souza D. Ultrasensitive determination of selenium in foodstuffs and beverages using an electroanalytical approach. Microchem J. 2021; 164:105996.
• 11. Wei H, Pan D, Cui Y, Liu H, Gao G, Xia J. Anodic stripping determination of selenium in seawater using an electrode modified with gold nanodendrites/perforated reduced graphene oxide. Int J Electrochem Sci. 2020; 15:1669-1680.
• 12. Kim IJ, Watson RP, Lindstrom RM. Accurate and precise measurement of selenium by instrumental neutron activation analysis. Anal Chem. 2011; 83(9):3493-3498.
• 13. Srivastava A, Bains GS, Acharya R, Reddy AVR. Study of seleniferous soils using instrumental neutron activation analysis. Appl Radiat Isot. 2011; 69(5):818-821.
• 14. El-Ghawi UM, Al-Fakhri SM, Al-Sadeq AA, Bejey MM, Doubali KK. The level of selenium and some other trace elements in different Libyan arable soils using instrumental neutron activation analysis. Biol Trace Elem Res. 2007; 119(1):89-96.
• 15. Messaoudi M, Begaa S. Radiochemical neutron activation analysis for the determination of selenium in Mentha spicata L. samples collected from Djelfa, Algeria region. Radiochim Acta. 2020; 108(3):217-222.
• 16. Pyrzynska K, Sentkowska A. Liquid chromatographic analysis of selenium species in plant materials. Trends Analyt Chem. 2019; 111:128-138.
• 17. Li YF, Chen C, Li B, Wang Q, Wang J, Gao Y, Zhao Y, Chai Z. Simultaneous speciation of selenium and mercury in human urine samples from long-term mercury-exposed populations with supplementation of selenium-enriched yeast by HPLC-ICP-MS. J Anal At Spectrom. 2007; 22(8):925-930.
• 18. Ballihaut G, Kilpatrick LE, Kilpatrick EL, Davis WC. Detection and characterization of selenoproteins by tandem mass spectrometry assisted by laser ablation inductively coupled plasma mass spectrometry: application to human plasma selenoproteins. J Anal At Spectrom. 2011; 26(2):383-394.
• 19. Jin F, Marcus RK. Selenium compound analysis by particle beam/ hollow cathode optical emission spectroscopy (PB/HC-OES): monitoring of carbon and hydrogen emission from organoselenium compounds. J Anal At Spectrom. 2003; 18(6):589-595.
• 20. Fang Z, Xu S, Tao G. Developments and trends in flow injection atomic absorption spectrometry. J Anal At Spectrom. 1996; 11(1):1- 24.
• 21. Chen D, Luque de Castro MD, Valcárcel M. Determination of anions by flow injection. A review. Analyst. 1991; 116(11):1095-1111.
• 22. Milovanović GA, Petronijević RB, Čakar MM. Kinetic determination of trace levels of selenium (IV) and total selenium by Nile Blue A/hydrogen peroxide method. Microchim Acta. 1998; 128(1):43-48.
• 23. Keyvanfard M, Sharifian A. Kinetic spectrophotometric method for the determination of selenium (IV) by its catalytic effect on the reduction of spadns by sulphide in micellar media. J Anal Chem. 2006; 61(6):596-600.
• 24. Zaporozhets OA, Bilikon SL. A visual test method for determining selenium(IV) with indigocarmine immobilized on silica. J Anal Chem. 2007; 62(2):188-192.
• 25. Absalan G, Safavi A, Maesum S. Application of artificial neural networks as a technique for interference removal: kinetic– spectrophotometric determination of trace amounts of Se (IV) in the presence of Te (IV). Talanta. 2001; 55(6):1227-1233.
• 26. Gainutdinova DF, Shirshova NV, Toropova VF, Budnikov GK, Garifzyanov AR. Reaction of 2, 3-dimethylmercaptopropionic acid with methylene Blue as an indicator reaction for the kinetic determination of selenium. J Anal Chem. 2001; 56(6):564-566.
• 27. Gudzenko LV, Pantaler RP, Blank AB. Catalytic spectrophotometric determination of nanogram amounts of selenium (IV). J Anal Chem. 2004; 59(10):935-938.
• 28. Huizhi LI, Diantang Z, Yingju F. Catalytic spectrophotometric determination of trace selenium in microemulsion after separation and enrichment by SDG. Rare Metals. 2006; 25(3):281-286.
• 29. Safavi A, Sedghy HR, Shams E. Kinetic spectrophotometric determination of trace amounts of selenium and vanadium. Fresenius J Anal Chem. 1999; 365(6):504-510.
• 30. Zhengjun G, Xinshen Z, Guohe C, Xinfeng X. Flow injection kinetic spectrophotometric determination of trace amounts of Se (IV) in seawater. Talanta. 2005; 66(4):1012-1017.
• 31. Rohn I, Marschall TA, Kroepfl N, Jensen KB, Aschner M, Tuck S, Kuehnelt D, Schwerdtle T, Bornhorst J. Selenium speciesdependent toxicity, bioavailability and metabolic transformations in Caenorhabditis elegans. Metallomics. 2018; 10(6):818-827.
• 32. Khajehsharifi H, Mousavi MF, Ghasemi J, Shamsipur M. Kinetic spectrophotometric method for simultaneous determination of selenium and tellurium using partial least squares calibration. Anal Chim Acta. 2004; 512(2):369-373.
• 33. Gürkan R, Akcay M. Kinetic spectrophotometric determination of trace amounts of selenium based on the catalytic reduction maxilon blue-SG by sulfide. Microchem J. 2003; 75(1):39-49.