A Review on the Vitamin D and In Vitro Fertilization Outcomes

Year 2017, , 252 - 259, 15.10.2017

Gamze Teskereci , İlkay Boz

https://doi.org/10.17681/hsp.283145

Abstract

CThe effect on
reproductive process of vitamin D is a controversial issue although the
function on the bone mineralization and maintaining of the calcium-phosphorus
balance of vitamin D is quite well-known. National and international studies
show that vitamin D deficiency is quite common among women of reproductive age. Vitamin D with sex steroids
are known to be effective in male and female reproductive processes. It supports the view that
the presence of the reproductive tissue of Vitamin D receptors and enzymes that
metabolize Vitamin D. In the literature, Vitamin D deficiency is associated
with etiologic factors of infertility such as fibroids, endometriosis,
polycystic ovary syndrome, low ovarian reserve, lower total sperm counts and
testosterone levels. In
this review, 13 research were achieved examining the impact on In Vitro
Fertilization results of Vitamin D. In our country, it could not be reached to
a study in this issue. Also, there are two systematic review in this issue. To routine monitoring of
vitamin D and promoting of treatment and care in the lack of Vitamin D,
large-scale, experimental and cohort studies are needed.

Keywords

Vitamin D, infertility, In Vitro Fertilization

D Vitamini ve İn Vitro Fertilizasyon Sonuçları Üzerine Bir Derleme

Abstract

D vitamininin kalsiyum-fosfor dengesinin
sürdürülmesi ve kemik mineralizasyonundaki fonksiyonu oldukça iyi bilinse de
üremeye etkisi tartışmalı bir konudur. Ulusal ve uluslararası çalışmalarda D
vitamini eksikliğinin üreme çağındaki kadınlarda oldukça yaygın olduğu görülmektedir.
D vitamininin seks steroid hormonlarıyla birlikte, kadın ve erkek üreme
süreçlerinde etkili olduğu bilinmektedir. D vitamini reseptörlerinin ve vitamini
metabolize eden enzimlerin üreme organlarında bulunması bu görüşü
desteklemektedir. D vitamini eksikliği; infertilitenin etiyolojik faktörleri
olan miyom, endometriozis, polikistik over, düşük ovarian reservi, düşük total
sperm sayısı ve testesteron düzeyi ile ilişkilendirilmektedir. D vitamini
eksikliğinin In Vitro Fertilizasyon sonuçları üzerinde etkilerini inceleyen 13
çalışmaya ulaşılmıştır. Ülkemizde bu konuda yapılan bir çalışmaya
ulaşılmamıştır. Ayrıca bu alanda yapılmış iki adet sistematik derleme
bulunmaktadır. Ancak tedavi öncesi rutin D vitamini takibi ve eksikliğine
ilişkin tedavi ve bakımın yaygınlaştırılması için büyük ölçekli, kohort ve
deneysel çalışmalara gereksinim vardır. 

Keywords

D vitamini, infertilite, In Vitro Fertilizasyon

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