Research Article

Thoracic computed tomography measures have predictive value in the diagnosis of chronic obstructive pulmonary disease

Volume: 2 Number: 4 October 17, 2022
  • Mustafa Tosun
  • Edhem Ünver
  • Ali Küpeli
  • Erdal Karavaş
  • Sonay Aydın

Thoracic computed tomography measures have predictive value in the diagnosis of chronic obstructive pulmonary disease

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is diagnosed with pulmonary function tests (PFTs). However, since not all patients can be diagnosed with PFTs, some are diagnosed with radiological or clinical findings. The purpose of this study was to define the properties of obstructive airway disease through thoracic computed tomography (CT) and to identify the diagnostic efficacy of CT findings. A total of 160 patients who underwent PFT and thoracic CT assessment July 2018 - January 2019, were retrospectively analyzed. Based on PFT findings, patients were categorized into three groups as having normal, restrictive or obstructive airways. Age, height, weight, and body mass indexes of the groups were recorded. Pulmonary height, width, right-left hemi-diaphragm height, sterno-diaphragmatic angle and retrosternal transparent area length in axial sections were also recorded. Diagnostic efficacies of these parameters in the detection of obstructive airway disease were measured. Of the 160 patients (109 males, 51 females; mean age = 59.5), 91 (56.9) had normal PFT, 58 (36.2%) had obstructive and 11 (6.9%) had restrictive airway disease. Pulmonary height, width, sterno-diaphragmatic angle, and retrosternal transparent area length were significantly higher in patients with obstructive airway disease while the right-left hemi-diaphragm height was significantly lower (p<0.001). About 60-75% sensitivity and specificity were obtained when identifying the obstructive airway disease with these parameters. These values obtained from the axial and sagittal sections could contribute to the diagnosis of obstructive airway disease.

Keywords

References

  1. 1. Patel AR, Patel AR, Singh S, Singh S, Khawaja I. Global initiative for chronic obstructive lung disease: The changes made. Cureus. 2019;11(6):e4985. doi: 10.7759/cureus.4985.
  2. 2. Rosenberg SR, Kalhan R, Mannino DM. Epidemiology of chronic obstructive pulmonary disease: Prevalence, morbidity, mortality, and risk factors. Semin Respir Crit Care Med. 2015;36(4):457–69. doi:10.1055/s-0035-1555607.
  3. 3. 2021 GOLD Reports - Global Initiative for Chronic Obstructive Lung Disease - GOLD. Accessed September 28, 2021. https://goldcopd.org/2021-gold-reports.
  4. 4. Messerli M, Ottilinger T, Warschkow R, Leschka S, Alkadhi H, Wildermuth S, et al. Emphysema quantification and lung volumetry in chest X-ray equivalent ultralow dose CT - Intra-individual comparison with standard dose CT. Eur J Radiol. 2017;91:1-9. doi: 10.1016/j.ejrad.2017.03.003.
  5. 5. Webb WR. Radiology of obstructive pulmonary disease. Am J Roentgenol. 1997;169(3):637–47. doi:10.2214/ajr.169.3.9275869.
  6. 6. Arakawa H, Kurihara Y, Nakajima Y, Niimi H, Ishikawa T, Tokuda M. Computed tomography measurements of overinflation in chronic obstructive pulmonary disease: Evaluation of various radiographic signs. J Thorac Imaging. 1998;13(3):188-92.doi:10.1097/00005382-199807000-00005.
  7. 7. Takasugi JE, Godwin JD. Radiology of chronic obstructive pulmonary disease. Radiol Clin North Am. 1998;36(1):29–55. doi:10.1016/S0033-8389(05)70006-3.
  8. 8. Kasai T, Yamada M, Narushima M, Suzuki H. [Relationship between thoracic cross-sectional area measured on CT and pulmonary function or dyspnea in patients with COPD]. Nihon Kokyuki Gakkai Zasshi. 2003;41(8):526–30.

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Mustafa Tosun This is me
0000-0002-5204-2099
Türkiye

Erdal Karavaş This is me
0000-0001-6649-3256
Türkiye

Sonay Aydın This is me
Türkiye

Publication Date

October 17, 2022

Submission Date

March 6, 2022

Acceptance Date

August 23, 2022

Published in Issue

Year 2022 Volume: 2 Number: 4

Vancouver
1.Mustafa Tosun, Edhem Ünver, Ali Küpeli, Erdal Karavaş, Sonay Aydın. Thoracic computed tomography measures have predictive value in the diagnosis of chronic obstructive pulmonary disease. Health Sci. Q. [Internet]. 2022 Oct. 1;2(4):187-96. Available from: https://izlik.org/JA86NX29SG