Epidemiologic and clinical evaluation of the acute intoxication in pediatric patients

Year 2021, Volume: 1 Issue: 2, 69 - 73, 27.07.2021

Mehmet Celegen

Abstract

Acute poisoning is a critical and emergent public health problem worldwide among pediatric age group. The common epidemiological observation is required to understand the characteristics of the pediatric intoxication for each location and important for management the poisoning cases. This retrospective study researched the epidemiology of poisoning among children. This study represented the epidemiology of poisonings of children admitted to the pediatric intensive care unit at Afyonkarahisar Health Science University Faculty of Medicine between February 2020 and May 2021. Fifty one pediatric patients were reffered to the PICU due to acute intoxication. 58.9% of the analyzed patients were male and 41.1% were female. The mean age of all patients was 8.57±7.6. The majority of cases were due to drug-related poisonings. The average age of cases of suicidal poisoning was higher than accidental intoxication cases. Paracetamol was the most prevalent cause of drug-related intoxication and more common in children under 5 years of age and selective serotonin reuptake inhibitors were more frequent in adolescent group. All patients survived. Almost all of the patients were
discharged from hospital within 3 days. Poisonings are still a serious reason for morbidity and mortality in developing countries among children. Early awareness of poisoning and appropriate management appeared to be effective and to decrease the mortality rate.

Keywords

poisoning, intensive care unit, pediatric management

References

• Ozdemir R, Bayrakci B, Teksam O, Yalcin B, Kale G. Thirty-three-year experience on childhood poisoning. The Turkish journal of pediatrics. 2012;54(3):251-9.
• Gummin DD, Mowry JB, Beuhler MC, Spyker DA, Brooks DE, Dibert KW, et al. 2019 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 37th Annual Report. Clinical toxicology. 2020;58(12):1360-541.
• Mutlu M, Cansu A, Karakas T, Kalyoncu M, Erduran E. Pattern of pediatric poisoning in the east Karadeniz region between 2002 and 2006: increased suicide poisoning. Human & experimental toxicology. 2010;29(2):131-6.
• Hincal F, Hincal AA, Muftu Y, Sarikayalar F, Ozer Y, Cevik N, et al. Epidemiological aspects of childhood poisonings in Ankara: a 10-year survey. Human toxicology. 1987;6(2):147-52.
• In: Peden M, Oyegbite K, Ozanne-Smith J, Hyder AA, Branche C, Rahman A, et al., editors. World Report on Child Injury Prevention. WHO Guidelines Approved by the Guidelines Review Committee. 2008 Geneva.
• Sahin S, Carman KB, Dinleyici EC. Acute poisoning in children; data of a pediatric emergency unit. Iranian journal of pediatrics. 2011;21(4):479-84.
• Tsalkidis A, Vaos G, Gardikis S, Kambouri K, Tripsianis G, Mantadakis E, et al. Acute poisoning among children admitted to a regional university hospital in Northern Greece. Central European journal of public health. 2010;18(4):219-23.
• Andiran N, Sarikayalar F. Pattern of acute poisonings in childhood in Ankara: what has changed in twenty years? The Turkish journal of pediatrics. 2004;46(2):147-52.
• Ozdogan H, Davutoglu M, Bosnak M, Tutanc M, Haspolat K. Pediatric poisonings in southeast of Turkey: epidemiological and clinical aspects. Human & experimental toxicology. 2008;27(1):45-8.
• Gunnell D, Ho D, Murray V. Medical management of deliberate drug overdose: a neglected area for suicide prevention? Emergency medicine journal : EMJ. 2004;21(1):35-8.
• Yang, CC, Wu, JF, Ong, HC, Hung, SC, Kuo, YP, Sa, CH, et al. Taiwan National Poison Center: epidemiologic data 1985–1993. Clin Toxicol. 1996;34: 651–663.
• Power KS. Diagnosis and management of common toxic ingestion and inhalations. Pediatr Ann. 2000;29(6)330-42.
• Jacobsen D, Halvorsen K, Marstrander J, Sunde K, Bakken AF. Acute poisonings of children in Oslo. A one-year prospective study. Acta Paediatr Scand. 1983;72: 553-557.