Research Article
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Year 2023, Volume: 3 Issue: 1, 43 - 47, 08.01.2023

Abstract

References

  • Talbot TR. Surgical site infectios and antimicrobial prophilaxis. In: Mandell GL, Bennett JE, Dolin R (Eds). Principles and Practice of Infectious Diseases. Seventh edition, Philadelphia, Churchill Livingstone, 2010. 3891-904 p.
  • Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for Prevention of Surgical Site Infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. Am J Infect Control. 1999;27(2):97-196.
  • Nemeth TA, Beilman GJ, Hamlin CL, Chipman JG. Preoperative verification of timely antimicrobial prophylaxis does not improve compliance with guidelines. Surg Infect (Larchmt). 2010;11(4):387- 91. doi:10.1089/sur.2008.054.
  • Koçak F, Balkan İİ, Çelik AD, Durdu B, Demirel A, Gencer S, et al. Compliance with guidelines for practices of perioperative antimicrobial prophylaxis: A multicenter survey. Anatolian Clin J Med Sci. 2017;22(1):8-15. doi: 10.21673/ anadoluklin.268873.
  • Hoşoğlu S. The problems of surgical prophylaxis and implementation in our system. ANKEM. 2004;18(2):185-87.
  • Soğancı A, Ünal E. Compatibility and cost analysis of surgical antibiotic prophylaxis in a mediumscale public hospital. Hacettepe J Health Admin. 2015;18(2):89-101.
  • Alaşehirli B, Oğuz E, Koruk S, Koruk İ, Karaoğlan İ, Çam Ö, et al. Evaluation of antibiotic prophylaxis in the University of Gaziantep Medical Faculty Research Hospital Surgical Departments. Gaziantep Med J. 2011;17(1):11-4.
  • Kurçer Z, Oğuz E, Kurçer MA, Tacir A, Ünal B, Uzunköy A, et al. Harran Üniversitesi Tıp Fakültesi Araştırma ve Uygulama Hastanesinde cerrahi profilaktik antibiyotik uygulamalarının değerlendirilmesi. (in Turkish). Klimik J. 2006;19(2):46-8.
  • Hyle EP, Bilker WB, Gasink LB, Lautenbach E. Impact of different methods for describing the extent of prior antibiotic exposure on the association between antibiotic use and antibioticresistant infection. Infect Control Hosp Epidemiol. 2007;28(6):647-54. doi:10.1086/516798.
  • Bratzler DW, Dellinger EP, Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Surg Infect (Larchmt). 2013;14(1):73-156. doi:10.1089/sur.2013.9999.
  • Burke JF. The effective period of preventive antibiotic action in experimental incisions and dermal lesions. Surgery. 1961;50:161-8.
  • Kalafat H, İ.Ü.Cerrahpaşa Tıp Fakültesi, Sürekli Tıp Eğitimi Etkinlikleri, Perioperatif antibiotik profilaksisi. 2008;60:193-206.
  • Fonseca SN, Kunzle SR, Junqueira MJ, Nascimento RT, de Andrade JI, Levin AS. Implementing 1-dose antibiotic prophylaxis for prevention of surgical site infection. Arch Surg. 2006;141(11):1109-14. doi:10.1001/archsurg.141.11.1109.
  • Öncü S. Antibiotic prophylaxis in surgery. Turkish J Surg. 2011;27(3):176-81. doi: 10.5097/1300-0705. UCD.906-11.01.
  • Kömür S, Ulu AC, Kurtaran B, Türkoğlu BÖ, İnal AZ, Kuşçu F, et al. One-day point prevalence study: Is surgical prophylaxis appropriate? Mustafa Kemal J Med. 2016;7(26):11-5. doi: 10.17944/mkutfd.67968.
  • Özkurt Z, Kadanalı A, Ertek M, Erol S, Parlak M. Antibiotic use in surgical prophylaxis. 2005;19(3):111-4.
  • Kaya S, Aktas S, Senbayrak S, et al. An evaluation of surgical prophylaxis procedures in Turkey: A multi-center point prevalence study. Eurasian J Med. 2016;48(1):24-8. doi:10.5152/ eurasianjmed.2015.15222.
  • Tuna N, Öğütlü A, Sandıkçı Ö, Ceylen S, Gözdaş HT, Altıntoprak F, et al. Review of surgical prophylaxis practice in a teaching hospital. ANKEM. 2010;24(2):92-5.
  • Hoşoğlu S. The problems of surgical prophylaxis and implementation in our system. ANKEM. 2004;18(2):185-7.
  • Aslan E, Özvatan TŞ, Özer D, Kazak E, Yılmaz E. Evaluation of practices in a university hospital surgical prophylaxis. J Uludag University Faculty Med. 2012;38(1):7-11.
  • Karahocagil MK, Er A, Kırıkçı AD, Sünnetçioğlu M, Yapıcı K, Bilici A, et al. Evaluation of antibiotic use in patients hospitalized in Yüzüncü Yıl University, Medical Faculty Research Hospital. Van Med J. 2007;14(2):46-51.

Evaluation of surgical antibiotic prophylaxis

Year 2023, Volume: 3 Issue: 1, 43 - 47, 08.01.2023

Abstract

Surgical prophylaxis is one of the areas where antibiotics are used commonly. In this study it is aimed surgical prophylaxis appropriateness and determination of cost analysis in our hospital. The study was performed November 30-15, 2018. 108 patients who underwent surgery in general surgery, orthopedics and neurosurgery clinics have been included in this prospective study. Patient selection was based on the classification of clean and cleancontaminated. Demographics, features of the surgery, applied prophylactic antibiotics and surgical prophylaxis appropriateness were recorded in the forms. All patient information forms were evaluated by infectious disease specialists using the surgical prophylaxis guide. The costs of unnecessary antibiotics were determined. Mean age of 108 patients who underwent a surgical procedure was 52.4 years and 39.8% of the patients were male and 60.2% were female. Of the surgery procedures 75.9% (n:82) were clean and 24.1% (n:26) clean-contaminated. Preoperative 58.3% (63) unnecessary antibiotic prophylaxis was detected. Continuing prophylaxis at a prolonged time were used in 99 (91.7%) patients in the postoperative period. Cefazolin is the most commonly used agent for surgical prophylaxis. The cost of unnecessary and long-term antibiotic use was determined as ₺6983,69. In this study, the time of antibiotic prophylaxis were to be a big problem. Prophylaxis often starts very early and continues for days. The wrong practices in surgical prophylaxis lead to unnecessary antibiotics treatment to the patients and also burden to the budget of the country.

References

  • Talbot TR. Surgical site infectios and antimicrobial prophilaxis. In: Mandell GL, Bennett JE, Dolin R (Eds). Principles and Practice of Infectious Diseases. Seventh edition, Philadelphia, Churchill Livingstone, 2010. 3891-904 p.
  • Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for Prevention of Surgical Site Infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. Am J Infect Control. 1999;27(2):97-196.
  • Nemeth TA, Beilman GJ, Hamlin CL, Chipman JG. Preoperative verification of timely antimicrobial prophylaxis does not improve compliance with guidelines. Surg Infect (Larchmt). 2010;11(4):387- 91. doi:10.1089/sur.2008.054.
  • Koçak F, Balkan İİ, Çelik AD, Durdu B, Demirel A, Gencer S, et al. Compliance with guidelines for practices of perioperative antimicrobial prophylaxis: A multicenter survey. Anatolian Clin J Med Sci. 2017;22(1):8-15. doi: 10.21673/ anadoluklin.268873.
  • Hoşoğlu S. The problems of surgical prophylaxis and implementation in our system. ANKEM. 2004;18(2):185-87.
  • Soğancı A, Ünal E. Compatibility and cost analysis of surgical antibiotic prophylaxis in a mediumscale public hospital. Hacettepe J Health Admin. 2015;18(2):89-101.
  • Alaşehirli B, Oğuz E, Koruk S, Koruk İ, Karaoğlan İ, Çam Ö, et al. Evaluation of antibiotic prophylaxis in the University of Gaziantep Medical Faculty Research Hospital Surgical Departments. Gaziantep Med J. 2011;17(1):11-4.
  • Kurçer Z, Oğuz E, Kurçer MA, Tacir A, Ünal B, Uzunköy A, et al. Harran Üniversitesi Tıp Fakültesi Araştırma ve Uygulama Hastanesinde cerrahi profilaktik antibiyotik uygulamalarının değerlendirilmesi. (in Turkish). Klimik J. 2006;19(2):46-8.
  • Hyle EP, Bilker WB, Gasink LB, Lautenbach E. Impact of different methods for describing the extent of prior antibiotic exposure on the association between antibiotic use and antibioticresistant infection. Infect Control Hosp Epidemiol. 2007;28(6):647-54. doi:10.1086/516798.
  • Bratzler DW, Dellinger EP, Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Surg Infect (Larchmt). 2013;14(1):73-156. doi:10.1089/sur.2013.9999.
  • Burke JF. The effective period of preventive antibiotic action in experimental incisions and dermal lesions. Surgery. 1961;50:161-8.
  • Kalafat H, İ.Ü.Cerrahpaşa Tıp Fakültesi, Sürekli Tıp Eğitimi Etkinlikleri, Perioperatif antibiotik profilaksisi. 2008;60:193-206.
  • Fonseca SN, Kunzle SR, Junqueira MJ, Nascimento RT, de Andrade JI, Levin AS. Implementing 1-dose antibiotic prophylaxis for prevention of surgical site infection. Arch Surg. 2006;141(11):1109-14. doi:10.1001/archsurg.141.11.1109.
  • Öncü S. Antibiotic prophylaxis in surgery. Turkish J Surg. 2011;27(3):176-81. doi: 10.5097/1300-0705. UCD.906-11.01.
  • Kömür S, Ulu AC, Kurtaran B, Türkoğlu BÖ, İnal AZ, Kuşçu F, et al. One-day point prevalence study: Is surgical prophylaxis appropriate? Mustafa Kemal J Med. 2016;7(26):11-5. doi: 10.17944/mkutfd.67968.
  • Özkurt Z, Kadanalı A, Ertek M, Erol S, Parlak M. Antibiotic use in surgical prophylaxis. 2005;19(3):111-4.
  • Kaya S, Aktas S, Senbayrak S, et al. An evaluation of surgical prophylaxis procedures in Turkey: A multi-center point prevalence study. Eurasian J Med. 2016;48(1):24-8. doi:10.5152/ eurasianjmed.2015.15222.
  • Tuna N, Öğütlü A, Sandıkçı Ö, Ceylen S, Gözdaş HT, Altıntoprak F, et al. Review of surgical prophylaxis practice in a teaching hospital. ANKEM. 2010;24(2):92-5.
  • Hoşoğlu S. The problems of surgical prophylaxis and implementation in our system. ANKEM. 2004;18(2):185-7.
  • Aslan E, Özvatan TŞ, Özer D, Kazak E, Yılmaz E. Evaluation of practices in a university hospital surgical prophylaxis. J Uludag University Faculty Med. 2012;38(1):7-11.
  • Karahocagil MK, Er A, Kırıkçı AD, Sünnetçioğlu M, Yapıcı K, Bilici A, et al. Evaluation of antibiotic use in patients hospitalized in Yüzüncü Yıl University, Medical Faculty Research Hospital. Van Med J. 2007;14(2):46-51.
There are 21 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Articles
Authors

Havva Tünay This is me 0000-0003-4333-082X

Publication Date January 8, 2023
Published in Issue Year 2023 Volume: 3 Issue: 1

Cite

Vancouver Tünay H. Evaluation of surgical antibiotic prophylaxis. Health Sci. Q. 2023;3(1):43-7.