The pathogenetic method of treatment of purulent wounds in dogs

Year 2020, Vetexpo-2019, KHVD-2019, 47 - 47, 31.03.2020

Alona Hierdieva Mykola Ilnitsky

Abstract

The effectiveness of the pathogenetic method of treatment of purulent wounds in dogs with on application
1,5 % solution of reamberine, prepared on its basis, was clinically, theoretically and experimentally
justified, which was confirmed by objective criteria for assessing the clinical condition of animals and by
morphological, biochemical studies. Treating dogs with purulent wounds included primary surgical
treatment of wounds, retention suture stitching and Levomecol ointment administration through passive
drainage application. 1,5 % solution of reamberine at a dose of 10 ml/kg body weight was injected
intravenously to animals of the experimental group were for 5 days. Dogs in the control group were
injected with 5 % glucose solution at a dose of 10 ml/kg of body weight for 5 days. The animals of
experimental group, which in took 1,5 % solution of reamberine, the absence of purulent exudates in the
cavity of the wound was found on the 3,2±0,18 day of treatment, i.e. 1,3 times (p<0,01) faster than that in
the control animals. The best therapeutic effect was obtained in the group of animals treated with
Reamberine. Wound healing and suture removal occurred on the 8,4±0,21 day of treatment, which was 1,3
(p<0,001) times faster compared with the control group. The recovery of blood parameters took less time
compared with the control animals: on the 7th day of treatment the level of MDA, fibrinogen, superoxide
dismutase (SOD) plasma activity, the percentage of total antioxidant activity (LAA) of plasma, and on the
10th day of treatment − the number of MSM, total protein, ceruloplasmine, catalase.

Keywords

purulent wound, dog, treatment

References

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