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Application of natural antioxidants as feed additives to improve animal health and enhance food quality in livestock farming

Year 2025, Volume: 9 Issue: 1, 38 - 46, 30.04.2025

Abstract

References

  • Abdel-Aal, E. S. M., Akhtar, H., Zaheer, K., & Ali, R. (2013). Dietary sources of lutein and zeaxanthin carotenoids and their role in eye health. Nutrients, 5(4), 1169-1185.
  • Ahsan, U., Kamran, Z., Raza, I., Ahmad, S., Babar, W., Riaz, M. H., & Iqbal, Z. (2014). Role of selenium in male reproduction—A review. Animal reproduction science, 146(1-2), 55-62.
  • Altıner, A., Atalay, H., & Bilal, T. (2017). Bir antioksidan olarak E vitamini. Balıkesir Sağlık Bilimleri Dergisi, 6(3), 149-157.
  • Amar, E. C., Kiron, V., Satoh, S., & Watanabe, T. (2004). Enhancement of innate immunity in rainbow trout (Oncorhynchus mykiss Walbaum) associated with dietary intake of carotenoids from natural products. Fish & shellfish immunology, 16(4), 527-537.
  • Arthur, J. R., McKenzie, R. C., & Beckett, G. J. (2003). Selenium in the immune system. The Journal of nutrition, 133(5), 1457S-1459S.
  • Aslankoç, R., Demirci, D., İnan, Ü., Yıldız, M., Öztürk, A., Çetin, M., ... & Yılmaz, B. (2019). Oksidatif stres durumunda antioksidan enzimlerin rolü-Süperoksit dismutaz (SOD), katalaz (CAT) ve glutatyon peroksidaz (GPX). Medical Journal of Süleyman Demirel University, 26(3), 362-369.
  • Atalay, H. (2011). Muğla yöresinde yetiştiriciliği yapılan Çipura ve Levrek balıklarının büyüme performansı ve yağ asidi profiline kullanılan farklı ticari yemlerin etkisi. Doktora Tezi. İ.Ü. Sağlık Bilimleri Enstitüsü, Hayvan Besleme ve Beslenme Hastalıkları ABD. İstanbul.
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  • Bayraktar, L. (2003). Broyler rasyonlarına Balık yağı, E ve C vitaminleri ilavesinin etteki yağ asidi kompozisyonuna ve besi performansına etkisi. Doktora Tezi. İ.Ü.Sağlık Bilimleri Enstitüsü, Hayvan Besleme ve Beslenme Hastalıkları ABD. İstanbul.
  • Bešlo, D., Golubić, N., Rastija, V., Agić, D., Karnaš, M., Šubarić, D., & Lučić, B. (2023). Antioxidant activity, metabolism, and bioavailability of polyphenols in the diet of animals. Antioxidants, 12(6), 1141.
  • Bingöl, G. (1981). Biyokimya. Ankara, Mis matbaası
  • Bravo, L. (1998). Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. Nutrition Reviews, 56(11), 317-333.
  • Burton, G. W., & Traber, M. G. (1990). Vitamin E: antioxidant activity, biokinetics, and bioavailability. Annual Review of Nutrition, 10(1), 357-382.
  • Chahar, G., Deshmukh, S., Banga, H.S. et al. (2024). Effect of feeding chitosan and blend of essential organic acids on growth performance, haematological parameters and innate immunity in early aged male layer chicks. Trop Anim Health Prod 56, 251
  • Cheng, Y. H., Shen, T. F., Pang, V. F., & Chen, B. J. (2011). Effects of dietary Vitamin E on the growth performance, immune response and carcass characteristics of broilers. British Poultry Science, 52(1), 94-100.
  • Chew, B. P. (1993). Role of carotenoids in the immune response. Journal of Dairy Science, 76(9), 2804-2811.
  • Chew, B. P., & Park, J. S. (2004). Carotenoid action on the immune response. The Journal of nutrition, 134(1), 257S-261S.
  • Çaylak, E. (2011). Hayvan ve bitkilerde oksidatif stres ile antioksidanlar. Tıp Araştırmaları Dergisi, 9(1):73-83.Derleme.
  • Çelik, S. A., & Ayran, İ. (2020). Antioksidan kaynaği olarak bazi tibbi ve aromatik bitkiler. Türk Bilimsel Derlemeler Dergisi, 13(2), 115-125.
  • Çetinkaya, N., Ünal, S., & Öztürk, A. (1997). Arpa samanina peyniralti suyu ilavesinin ankara keçilerinde rumende parçalanabilirlik, rumen fermentasyonu ve oğlaklarda canli ağirlik artişi, tiftik verimi ve kalitesine etkisi. Lalahan Hayvancılık Araştırma Enstitüsü Dergisi, 37(1), 56-64.
  • Dai, H., Lv, Z., Huang, Z., Ye, N., Li, S., Jiang, J., ... & Shi, F. (2021). Dietary hawthorn-leaves flavonoids improves ovarian function and liver lipid metabolism in aged breeder hens. Poultry Science, 100(12), 101499.
  • Dalia, A. M., Loh, T. C., Sazili, A. Q., Jahromi, M. F., & Samsudin, A. A. (2018). Effects of vitamin E, inorganic selenium, bacterial organic selenium, and their combinations on immunity response in broiler chickens. BMC Veterinary Research, 14, 1-10.
  • Davis, P. A. (2004). Selenium tolerance in sheep and selenium supplementation methods for beef cattle (Order No. 3160995). Available from ProQuest Dissertations & Theses Global. (305183280). Retrieved from https://www.proquest.com/dissertations-theses/selenium-tolerance-sheep-supplementation-methods/docview/305183280/se-2
  • Decker, E. A., Akoh, C. C., & Wilkes, R. S. (2012). Incorporation of (n-3) fatty acids in foods: challenges and opportunities. The Journal of Nutrition, 142(3), 610S-613S.
  • Dueñas, M., Muñoz-González, I., Cueva, C., Jiménez-Girón, A., Sánchez-Patán, F., Santos-Buelga, C., ... & Bartolomé, B. (2015). A survey of modulation of gut microbiota by dietary polyphenols. BioMed Research International, 2015(1), 850902.
  • El-Zaiat, H.M., Al-Marzooqi, W. and Al-Kharousi, K. (2025), Effects of Chitosan-Based Additive on Rumen Fermentation and Microbial Community, Nutrients Digestibility and Lactation Performance in Goats. Journal of Animal Physiology and Animal Nutrition. 2024; 1–12 https://doi.org/10.1111/jpn.14057
  • Fellenberg, M. A., & Speisky, H. (2006). Antioxidants: their effects on broiler oxidative stress and its meat oxidative stability. World's Poultry Science Journal, 62(1), 53-70.
  • Galasso, C., Orefice, I., Pellone, P., Cirino, P., Miele, R., Ianora, A., ... & Sansone, C. (2018). On the neuroprotective role of astaxanthin: new perspectives?. Marine Drugs, 16(8), 247.
  • German, J. B., Dillard, C. J., & Walzem, R. L. (2000). US Whey products and dairy ingredients for health, a review. Applications Monograph.
  • Gopi, M., Karthik, K., Manjunathachar, H. V., Tamilmahan, P., Kesavan, M., Dashprakash, M., ... & Purushothaman, M. R. (2014). Essential oils as a feed additive in poultry nutrition. Advances in Animal and Veterinary Sciences, 2(1), 1-7.
  • Guerra-Rivas, C., Vieira, C., Rubio, B., Martínez, B., Gallardo, B., Mantecón, A. R., ... & Manso, T. (2016). Effects of grape pomace in growing lamb diets compared with vitamin E and grape seed extract on meat shelf life. Meat Science, 116, 221-229.
  • Harper, W. J. (2004). Biological properties of whey components.
  • He, L., He, T., Farrar, S., Ji, L., Liu, T., & Ma, X. (2017). Antioxidants maintain cellular redox homeostasis by elimination of reactive oxygen species. Cellular Physiology and Biochemistry, 44(2), 532-553.
  • Ioannone, F., Miglio, C., Raguzzini, A., & Serafini, M. (2013). Flavonoids and immune function. In Diet, Immunity and Inflammation (pp. 379-415). Woodhead Publishing.
  • İmik, H., Ak, Y., Polat, H., & Gümüş, R. (2009). Yumurta tavuklarında rasyona farklı oranlarda katılan sorgumun (Sorghum vulgare) serum glikoz, lipid protein, glutatyon peroksidaz ve malondialdehit üzerine etkisi. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 15(3).
  • Juniper, D. T., Phipps, R. H., Jones, A. K., & Bertin, G. (2006). Selenium supplementation of lactating dairy cows: effect on selenium concentration in blood, milk, urine, and feces. Journal of Dairy Science, 89(9), 3544-3551.
  • Karabulut, H., & Gülay, M. Ş. (2016). Antioksidanlar. Veterinary Journal of Mehmet Akif Ersoy University, 1(1), 65-76.
  • Karagözlü, C., & Bayarer, M. (2004). Peyniraltı suyu proteinlerinin fonksiyonel özellikleri ve sağlık üzerine etkileri. Ege Üniversitesi Ziraat Fakültesi Dergisi, 41(2).
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Application of natural antioxidants as feed additives to improve animal health and enhance food quality in livestock farming

Year 2025, Volume: 9 Issue: 1, 38 - 46, 30.04.2025

Abstract

Feed additives are used in animal nutrition for a variety of reasons, including improving feed quality, regulating rumen fermentation, increasing product quality and yield, and improving animal health. Antioxidant feed additives are essential compounds that preserve feed from oxidation. The oxidation process degrades lipids in feed components, reducing their nutritional value. Consequently, animal health suffers, and productivity decreases. Antioxidant additives are used to protect the nutritional value of feeds, particularly high-fat rations. This review focuses on the antioxidant feed additives that are commonly used in animal nutrition.

References

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  • Ahsan, U., Kamran, Z., Raza, I., Ahmad, S., Babar, W., Riaz, M. H., & Iqbal, Z. (2014). Role of selenium in male reproduction—A review. Animal reproduction science, 146(1-2), 55-62.
  • Altıner, A., Atalay, H., & Bilal, T. (2017). Bir antioksidan olarak E vitamini. Balıkesir Sağlık Bilimleri Dergisi, 6(3), 149-157.
  • Amar, E. C., Kiron, V., Satoh, S., & Watanabe, T. (2004). Enhancement of innate immunity in rainbow trout (Oncorhynchus mykiss Walbaum) associated with dietary intake of carotenoids from natural products. Fish & shellfish immunology, 16(4), 527-537.
  • Arthur, J. R., McKenzie, R. C., & Beckett, G. J. (2003). Selenium in the immune system. The Journal of nutrition, 133(5), 1457S-1459S.
  • Aslankoç, R., Demirci, D., İnan, Ü., Yıldız, M., Öztürk, A., Çetin, M., ... & Yılmaz, B. (2019). Oksidatif stres durumunda antioksidan enzimlerin rolü-Süperoksit dismutaz (SOD), katalaz (CAT) ve glutatyon peroksidaz (GPX). Medical Journal of Süleyman Demirel University, 26(3), 362-369.
  • Atalay, H. (2011). Muğla yöresinde yetiştiriciliği yapılan Çipura ve Levrek balıklarının büyüme performansı ve yağ asidi profiline kullanılan farklı ticari yemlerin etkisi. Doktora Tezi. İ.Ü. Sağlık Bilimleri Enstitüsü, Hayvan Besleme ve Beslenme Hastalıkları ABD. İstanbul.
  • Bai, X., Li, F., Li, F., & Guo, L. (2022). Different dietary sources of selenium alter meat quality, shelf life, selenium deposition, and antioxidant status in Hu lambs. Meat Science, 194, 108961.
  • Bayraktar, L. (2003). Broyler rasyonlarına Balık yağı, E ve C vitaminleri ilavesinin etteki yağ asidi kompozisyonuna ve besi performansına etkisi. Doktora Tezi. İ.Ü.Sağlık Bilimleri Enstitüsü, Hayvan Besleme ve Beslenme Hastalıkları ABD. İstanbul.
  • Bešlo, D., Golubić, N., Rastija, V., Agić, D., Karnaš, M., Šubarić, D., & Lučić, B. (2023). Antioxidant activity, metabolism, and bioavailability of polyphenols in the diet of animals. Antioxidants, 12(6), 1141.
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  • Bravo, L. (1998). Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. Nutrition Reviews, 56(11), 317-333.
  • Burton, G. W., & Traber, M. G. (1990). Vitamin E: antioxidant activity, biokinetics, and bioavailability. Annual Review of Nutrition, 10(1), 357-382.
  • Chahar, G., Deshmukh, S., Banga, H.S. et al. (2024). Effect of feeding chitosan and blend of essential organic acids on growth performance, haematological parameters and innate immunity in early aged male layer chicks. Trop Anim Health Prod 56, 251
  • Cheng, Y. H., Shen, T. F., Pang, V. F., & Chen, B. J. (2011). Effects of dietary Vitamin E on the growth performance, immune response and carcass characteristics of broilers. British Poultry Science, 52(1), 94-100.
  • Chew, B. P. (1993). Role of carotenoids in the immune response. Journal of Dairy Science, 76(9), 2804-2811.
  • Chew, B. P., & Park, J. S. (2004). Carotenoid action on the immune response. The Journal of nutrition, 134(1), 257S-261S.
  • Çaylak, E. (2011). Hayvan ve bitkilerde oksidatif stres ile antioksidanlar. Tıp Araştırmaları Dergisi, 9(1):73-83.Derleme.
  • Çelik, S. A., & Ayran, İ. (2020). Antioksidan kaynaği olarak bazi tibbi ve aromatik bitkiler. Türk Bilimsel Derlemeler Dergisi, 13(2), 115-125.
  • Çetinkaya, N., Ünal, S., & Öztürk, A. (1997). Arpa samanina peyniralti suyu ilavesinin ankara keçilerinde rumende parçalanabilirlik, rumen fermentasyonu ve oğlaklarda canli ağirlik artişi, tiftik verimi ve kalitesine etkisi. Lalahan Hayvancılık Araştırma Enstitüsü Dergisi, 37(1), 56-64.
  • Dai, H., Lv, Z., Huang, Z., Ye, N., Li, S., Jiang, J., ... & Shi, F. (2021). Dietary hawthorn-leaves flavonoids improves ovarian function and liver lipid metabolism in aged breeder hens. Poultry Science, 100(12), 101499.
  • Dalia, A. M., Loh, T. C., Sazili, A. Q., Jahromi, M. F., & Samsudin, A. A. (2018). Effects of vitamin E, inorganic selenium, bacterial organic selenium, and their combinations on immunity response in broiler chickens. BMC Veterinary Research, 14, 1-10.
  • Davis, P. A. (2004). Selenium tolerance in sheep and selenium supplementation methods for beef cattle (Order No. 3160995). Available from ProQuest Dissertations & Theses Global. (305183280). Retrieved from https://www.proquest.com/dissertations-theses/selenium-tolerance-sheep-supplementation-methods/docview/305183280/se-2
  • Decker, E. A., Akoh, C. C., & Wilkes, R. S. (2012). Incorporation of (n-3) fatty acids in foods: challenges and opportunities. The Journal of Nutrition, 142(3), 610S-613S.
  • Dueñas, M., Muñoz-González, I., Cueva, C., Jiménez-Girón, A., Sánchez-Patán, F., Santos-Buelga, C., ... & Bartolomé, B. (2015). A survey of modulation of gut microbiota by dietary polyphenols. BioMed Research International, 2015(1), 850902.
  • El-Zaiat, H.M., Al-Marzooqi, W. and Al-Kharousi, K. (2025), Effects of Chitosan-Based Additive on Rumen Fermentation and Microbial Community, Nutrients Digestibility and Lactation Performance in Goats. Journal of Animal Physiology and Animal Nutrition. 2024; 1–12 https://doi.org/10.1111/jpn.14057
  • Fellenberg, M. A., & Speisky, H. (2006). Antioxidants: their effects on broiler oxidative stress and its meat oxidative stability. World's Poultry Science Journal, 62(1), 53-70.
  • Galasso, C., Orefice, I., Pellone, P., Cirino, P., Miele, R., Ianora, A., ... & Sansone, C. (2018). On the neuroprotective role of astaxanthin: new perspectives?. Marine Drugs, 16(8), 247.
  • German, J. B., Dillard, C. J., & Walzem, R. L. (2000). US Whey products and dairy ingredients for health, a review. Applications Monograph.
  • Gopi, M., Karthik, K., Manjunathachar, H. V., Tamilmahan, P., Kesavan, M., Dashprakash, M., ... & Purushothaman, M. R. (2014). Essential oils as a feed additive in poultry nutrition. Advances in Animal and Veterinary Sciences, 2(1), 1-7.
  • Guerra-Rivas, C., Vieira, C., Rubio, B., Martínez, B., Gallardo, B., Mantecón, A. R., ... & Manso, T. (2016). Effects of grape pomace in growing lamb diets compared with vitamin E and grape seed extract on meat shelf life. Meat Science, 116, 221-229.
  • Harper, W. J. (2004). Biological properties of whey components.
  • He, L., He, T., Farrar, S., Ji, L., Liu, T., & Ma, X. (2017). Antioxidants maintain cellular redox homeostasis by elimination of reactive oxygen species. Cellular Physiology and Biochemistry, 44(2), 532-553.
  • Ioannone, F., Miglio, C., Raguzzini, A., & Serafini, M. (2013). Flavonoids and immune function. In Diet, Immunity and Inflammation (pp. 379-415). Woodhead Publishing.
  • İmik, H., Ak, Y., Polat, H., & Gümüş, R. (2009). Yumurta tavuklarında rasyona farklı oranlarda katılan sorgumun (Sorghum vulgare) serum glikoz, lipid protein, glutatyon peroksidaz ve malondialdehit üzerine etkisi. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 15(3).
  • Juniper, D. T., Phipps, R. H., Jones, A. K., & Bertin, G. (2006). Selenium supplementation of lactating dairy cows: effect on selenium concentration in blood, milk, urine, and feces. Journal of Dairy Science, 89(9), 3544-3551.
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There are 76 citations in total.

Details

Primary Language English
Subjects Veterinary Sciences (Other)
Journal Section Review Articles
Authors

Hasan Atalay 0000-0002-5744-7538

Hatibe Kara 0000-0002-7037-3940

Publication Date April 30, 2025
Submission Date October 17, 2024
Acceptance Date March 7, 2025
Published in Issue Year 2025 Volume: 9 Issue: 1

Cite

APA Atalay, H., & Kara, H. (2025). Application of natural antioxidants as feed additives to improve animal health and enhance food quality in livestock farming. Journal of Istanbul Veterinary Sciences, 9(1), 38-46.

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