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Birinci Basamak Tedavi Hizmetlerinde Baş Ağrılarına Yaklaşım: Eczacının Rolü

Year 2013, Issue: 1, 75 - 104, 01.01.2013

Abstract

Primer baş ağrıları, yaygın gözlenen kronik ağrı sendromlarından biri olup, toplumun her kesimini etkileyebilmektedir. Basit analjezik ve non-steroidal anti-inflamatuvar ilaçların kullanımı ile özellikle akut tedavilerde etkili ağrı kontrolü sağlanmakla birlikte, baş ağrısı tiplerinin arasındaki farkların toplum tarafından yeteri kadar bilinmemesi, yanlış ve gereksiz ilaç kullanımına yol açmakta ve baş ağrısının süresini uzatarak tedavinin etkinliğini azaltmaktadır. Atak döneminde veya episodik durumlarda kısa süreli olarak kullanılması öngörülen triptanların, önerilen doz ve sıklıktan daha fazla olarak hasta tarafından kullanılması yan etki gözlenme sıklığını arttırmakta ve ilaç aşırı kullanımına bağlı baş ağrısı gelişmesine sebep olmaktadır. Uzun dönem tedavide kullanılan adjuvan analjezikler ile uygulanan tedavi prensiplerinin hasta tarafından tam olarak anlaşılmaması ilaç tedavi sürelerinin optimize edilmesini zorlaştırmakta ve beklenen etkinin gözlenmemesine neden olmakta ve bunun sonucunda hastanın yaşam kalitesini azalmaktadır. İlaçla ilgili sorunların birinci basamakta hastanın ‘ilk başvuru noktası’ olarak gördükleri eczacılar tarafından önceden fark edilerek, gerekli danışmanlık hizmetinin verilmesi ve ikinci basamak tedaviye erken yönlendirilmesi; hem gereksiz ilaç tedavileri ve buna bağlı gelişen sosyo-ekonomik olumsuzlukları en aza indirecek, hem de birinci ve ikinci basamak sağlık personeli arasındaki koordinasyonu sağlayarak ağrı tedavisindeki başarıyı artıracaktır. Sağlık sistemindeki bu kesintisiz iletişimin ve multidisipliner çalışmanın sağlanabilmesi için eczacının sorumluluklarının ve danışmanlık hizmetinin hastalar ve diğer sağlık personeli tarafından benimsenmesi ve ekip içerisinde hizmet verebilmesi için gerekli altyapı ve uygulamaların sağlanması gerekmektedir.

References

  • Baykan B, Ertas M, Karli N, Akat-Aktas S, Uzunkaya O, Zarifoglu M, et al.: The burden of headache in neurology outpatient clinics in Turkey. Pain Pract,7(4):313-23 (2007).
  • Goadsby PJ. Recent advances in the diagnosis and management of migraine. BMJ, 332(7532):25-9 (2006).
  • Mueller LL. Diagnosing and managing migraine headache. J Am Osteopath Assoc, 107(10 Suppl 6):ES10-6 (2007).
  • Loder E, Rizzoli P.: Tension-type headache. BMJ, 336(7635):88-92 (2008).
  • Turkdogan D, Cagirici S, Soylemez D, Sur H, Bilge C, Turk U. Characteristic and overlap- ping features of migraine and tension-type headache. Headache , 46(3):461-8 (2006).
  • Hershey AD, Winner P, Kabbouche MA, Powers SW. Headaches. Curr Opin Pedi- atr,19(6):663-9 (2007).
  • MacGregor E A, Steiner T J, G DPT. Guidelines for All Healthcare Professionals in the Di- agnosis and Management of Migraine, Tension-Type, Cluster and Medication-Overuse Headache, British Association for the Study of Headache (BASH) Guideline. 2010.
  • Buse DC, Rupnow MF, Lipton RB. Assessing and managing all aspects of migraine: mi- graine attacks, migraine-related functional impairment, common comorbidities, and quality of life. Mayo Clinic proceedings. Mayo Clinic,84(5):422-35 (2009).
  • Stovner LJ, Andree C. Prevalence of headache in Europe: a review for the Eurolight proj- ect. J Headache Pain, 11(4):289-99 (2010).
  • Koseoglu E, Nacar M, Talaslioglu A, Cetinkaya F. Epidemiological and clinical charac- teristics of migraine and tension type headache in 1146 females in Kayseri, Turkey. Cephalalgia, 23(5):381-8 (2003).
  • Kececi H, Dener S. Epidemiological and clinical characteristics of migraine in Sivas, Turkey. Headache, 42(4):275-80 (2002).
  • Aygul R, Deniz O, Kocak N, Orhan A, Ulvi H. The clinical properties of a migrainous population in eastern Turkey-Erzurum. Southern Medical Journal, 98(1):23-7 (2005).
  • Ertas M, Siva A, Dalkara T, Uzuner N, Dora B, Inan L, et al. Validity and reliability of the Turkish Migraine Disability Assessment (MIDAS) questionnaire. Headache, 44(8):786- 93 (2004).
  • Kutlu A, Yaluğ İ, Mülayim S, Temel Obuz E, Selekler M. Trigger factors of migraine. Nöropsikiyatri Arşivi,47:58-63 (2010).
  • Bag B, Karabulut N. Pain-relieving factors in migraine and tension-type headache. In- ternational Journal of Clinical Practice, 59(7):760-3 (2005).
  • Karli N, Zarifoglu M, Calisir N, Akgoz S. Comparison of pre-headache phases and trigger factors of migraine and episodic tension-type headache: do they share similar clinical pathophysiology? Cephalalgia, 25(6):444-51 (2005).
  • Ertas M, Baykan B, Kocasoy Orhan E, Zarifoglu M, Karli N, Saip S, et al. One-year prev- alence and the impact of migraine and tension-type headache in Turkey: a nationwide home-based study in adults. J Headache Pain,13:147-57 (2012).
  • Steiner TJ, Paemeleire K, Jensen R, Valade D, Savi L, Lainez MJ, et al. European prin- ciples of management of common headache disorders in primary care. J Headache Pain, 8 Suppl 1:S3-47 (2007).
  • Thomas E, Boardman HF, Ogden H, Millson DS, Croft PR. Advice and care for head- aches: who seeks it, who gives it? Cephalalgia,24(9):740-52 (2004).
  • Wenzel RG, Lipton RB, Diamond ML, Cady R. Migraine therapy: a survey of pharmacists’ knowledge, attitudes, and practice patterns. Headache, 45(1):47-52 (2005).
  • Harpole LH, Samsa GP, Matchar DB, Silberstein SD, Blumenfeld A, Jurgelski AE. Bur- den of illness and satisfaction with care among patients with headache seen in a pri- mary care setting. Headache, 45(8):1048-55 (2005).
  • Tellez-Zenteno JF. Economic impact of primary headaches. J Headache Pain,7(2):57-9 (2006).
  • Karli N, Zarifoglu M, Ertaş M, Saip S, Ozturk V, Bicakci S, et al. Economic impact of primary headaches in Turkey: a university hospital based study: part II. J Headache Pain,7(2):75-82 (2006).
  • Selekler HM, Komsuoglu S. Unconventional treatment methods in Turkish migraine sufferers. J Headache Pain,5:197-200 (2004).
  • Gedikoglu U, Coskun O, Inan LE, Ucler S, Tunc T, Emre U. Validity and reliability of Turkish translation of Migraine Disability Assessment (MIDAS) questionnaire in pa- tients with migraine. Cephalalgia, 25(6):452-6 (2005).
  • Gedikoglu U, Ucler S, Inan LE, Coskun O, Tunc T. A preliminary study: validity and reli- ability of Turkish translation of migraine disability assessment (MIDAS) questionnaire in Turkish patients with chronic tension type headache. The International Journal of Neuroscience,116(11):1337-45 (2006).
  • Jensen R, Tassorelli C, Rossi P, Allena M, Osipova V, Steiner T, et al. A basic diagnostic headache diary (BDHD) is well accepted and useful in the diagnosis of headache. a multicentre European and Latin American study. Cephalalgia,31(15):1549-60 (2011).
  • Evers S, Afra J, Frese A, Goadsby PJ, Linde M, May A, et al. EFNS guideline on the drug treatment of migraine - report of an EFNS task force. European journal of neurology : the official journal of the European Federation of Neurological Societies,13(6):560-72 (2006).
  • Evers S, Afra J, Frese A, Goadsby PJ, Linde M, May A, et al. EFNS guideline on the drug treatment of migraine--revised report of an EFNS task force. European journal of neurology : the official journal of the European Federation of Neurological Societies, 16(9):968-81 (2009).
  • MacGregor EA, Steiner TJ, Davies PTG. Guidelines for All Healthcare Professionals in the Diagnosis and Management of Migraine, Tension-Type, Cluster and Medication- Overuse Headache. 3rd Edition ed: The British Association for the Study of Headache, 2010.
  • Türk Nöroloji Derneği: Başağrısı Tanı ve Tedavi Rehberi (2011 Güncelleşmiş şekli) In: Erdemoğlu AK (ed), Türk Nöroloji Derneği,1-56 (2011).
  • Pesaturo K, Wooding F. Modern management of the migraine headache. American Jour- nal of Lifestyle Medicine,3:147-59 (2009).
  • MacGregor E A, Steiner T J, G DPT. Guidelines for All Healthcare Professionals in the Diagnosis and Management of Migraine, Tension-Type, Cluster and Medication- Overuse Headache. 3rd edition (1st revision) ed: British Association for the Study of Headache, 2010.
  • Derry S, Moore RA, McQuay HJ. Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults. Cochrane Database Syst Rev (11):CD008040 (2010).
  • Kirthi V, Derry S, Moore RA, McQuay HJ. Aspirin with or without an antiemetic for acute migraine headaches in adults. Cochrane Database Syst Rev (4):CD008041 (2010).
  • Rabbie R, Derry S, Moore RA, McQuay HJ. Ibuprofen with or without an antiemetic for acute migraine headaches in adults. Cochrane Database Syst Rev (10):CD008039 (2010).
  • Derry S, Rabbie R, Moore RA. Diclofenac with or without an antiemetic for acute mi- graine headaches in adults. Cochrane Database Syst Rev,2:CD008783 (2012).
  • Bendtsen L, Jensen R. Treating tension-type headache -- an expert opinion. Expert Opinion on Pharmacotherapy,12(7):1099-109 (2011).
  • Lampl C, Voelker M, Steiner TJ. Aspirin is first-line treatment for migraine and episodic tension-type headache regardless of headache intensity. Headache,52(1):48-56 (2012).
  • Mett A, Tfelt-Hansen P. Acute migraine therapy: recent evidence from randomized com- parative trials. Current Opinion in Neurology,21(3):331-7 (2008).
  • Holland S, Silberstein SD, Freitag F, Dodick DW, Argoff C, Ashman E. Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology,78(17):1346-53 (2012).
  • Tepper S, Allen C, Sanders D, Greene A, Boccuzzi S. Coprescription of triptans with potentially interacting medications: a cohort study involving 240,268 patients. Head- ache,43(1):44-8 (2003).
  • Ferrari A, Sternieri E, Ferraris E, Bertolini A. Emerging problems in the pharmacology of migraine: interactions between triptans and drugs for prophylaxis. Pharmacological research : the official journal of the Italian Pharmacological Society,48(1):1-9 (2003).
  • Loder E. Triptan therapy in migraine. The New England Journal of Medicine,363(1):63-70 (2010).
  • Dowson AJ, Tepper SJ, Dahlof C. Patients’ preference for triptans and other medica- tions as a tool for assessing the efficacy of acute treatments for migraine. J Headache Pain, 6(3):112-20 (2005).
  • Gallagher RM, Kunkel R. Migraine medication attributes important for patient compli- ance: concerns about side effects may delay treatment. Headache,43(1):36-43 (2003).
  • Mullins CD, Weis KA, Perfetto EM, Subedi PR, Healey PJ. Triptans for migraine therapy: a comparison based on number needed to treat and doses needed to treat. Journal of Managed Care Pharmacy : JMCP,11(5):394-402 (2005).
  • Ferrari MD, Roon KI, Lipton RB, Goadsby PJ. Oral triptans (serotonin 5-HT(1B/1D) agonists) in acute migraine treatment: a meta-analysis of 53 trials. Lan- cet,358(9294):1668-75 (2001).
  • Culley EJ. Which is more elusive, the pot of gold at the end of a rainbow or determining the most cost-effective triptan? Journal of Managed Care Pharmacy : JMCP,11(6):513-5 (2005).
  • Whyte C, Tepper SJ, Evans RW. Expert opinion: Rescue me: rescue medication for mi- graine. Headache,50(2):307-13 (2010).
  • Diamond ML, Wenzel RG, Nissan GR. Optimizing migraine therapy: evidence-based and patient-centered care. Expert Review of Neurotherapeutics,6(6):911-9 (2006).
  • Rapoport AM. New acute treatments for headache. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiol- ogy,31 Suppl 1:S129-32 (2010).
  • Evers S. Treatment of migraine with prophylactic drugs. Expert Opinion on Pharmaco- therapy,9(15):2565-73 (2008).
  • Whyte CA, Tepper SJ. Adverse effects of medications commonly used in the treatment of migraine. Expert Review of Neurotherapeutics,9(9):1379-91 (2009).
  • Antonaci F, Dumitrache C, De Cillis I, Allena M. A review of current European treatment guidelines for migraine. J Headache Pain,11(1):13-9 (2010).
  • Gales BJ, Bailey EK, Reed AN, Gales MA. Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for the prevention of migraines. The Annals of Pharmaco- therapy,44(2):360-6 (2010).
  • D’Amico D, Tepper SJ. Prophylaxis of migraine: general principles and patient accep- tance. Neuropsychiatric Disease and Treatment, 4(6):1155-67 (2008).
  • Evans RW, Rizzoli P, Loder E, Bana D. Beta-blockers for migraine. Headache,48(3):455-60 (2008).
  • Jackson JL, Shimeall W, Sessums L, Dezee KJ, Becher D, Diemer M, et al. Tricyclic antidepressants and headaches: systematic review and meta-analysis. BMJ,341:c5222
  • Moja PL, Cusi C, Sterzi RR, Canepari C. Selective serotonin re-uptake inhibitors (SS- RIs) for preventing migraine and tension-type headaches. Cochrane Database Syst Rev (3):CD002919 (2005).
  • Krishnan A, Silver N. Headache (chronic tension-type). BMJ Clinical Evidence (Online), 3-40 (2009).
  • Dodick DW, Freitag F, Banks J, Saper J, Xiang J, Rupnow M, et al. Topiramate ver- sus amitriptyline in migraine prevention: a 26-week, multicenter, randomized, double- blind, double-dummy, parallel-group noninferiority trial in adult migraineurs. Clinical Therapeutics,31(3):542-59 (2009).
  • Adelman J, Freitag FG, Lainez M, Shi Y, Ascher S, Mao L, et al. Analysis of safety and tolerability data obtained from over 1,500 patients receiving topiramate for migraine prevention in controlled trials. Pain Med,9(2):175-85 (2008).
  • Edvinsson L, Linde M. New drugs in migraine treatment and prophylaxis: telcagepant and topiramate. Lancet,376(9741):645-55 (2010).
  • Bussone G, Diener HC, Pfeil J, Schwalen S. Topiramate 100 mg/day in migraine pre- vention: a pooled analysis of double-blind randomised controlled trials. International Journal of Clinical Practice,59(8):961-8 (2005).
  • Ferrari A, Tiraferri I, Neri L, Sternieri E. Clinical pharmacology of topiramate in mi- graine prevention. Expert Opinion on Drug Metabolism & Toxicology,7(9):1169-81 (2011).
  • Keskinbora K, Aydinli I. A double-blind randomized controlled trial of topiramate and amitriptyline either alone or in combination for the prevention of migraine. Clinical Neurology and Neurosurgery,110(10):979-84 (2008).
  • Bulut S, Berilgen MS, Baran A, Tekatas A, Atmaca M, Mungen B. Venlafaxine ver- sus amitriptyline in the prophylactic treatment of migraine: randomized, double-blind, crossover study. Clinical Neurology and Neurosurgery,107(1):44-8 (2004).
  • Mulleners WM, Chronicle EP. Anticonvulsants in migraine prophylaxis: a Cochrane review. Cephalalgia,28(6):585-97 (2008).
  • Afshari D, Rafizadeh S, Rezaei M. A comparative study of the effects of low-dose topi- ramate versus sodium valproate in migraine prophylaxis. The International Journal of Neuroscience,122(2):60-8 (2012).
  • Yurekli VA, Akhan G, Kutluhan S, Uzar E, Koyuncuoglu HR, Gultekin F. The effect of so- dium valproate on chronic daily headache and its subgroups. J Headache Pain,9(1):37- 41 (2008).
  • Krymchantowski AV, Jevoux Cda C. Low-dose topiramate plus sodium divalproate for positive responders intolerant to full-dose monotherapy. Headache,52(1):129-32 (2012).
  • Ergun H, Gulmez SE, Tulunay FC. Cost-minimization analysis comparing topiramate with standard treatments in migraine prophylaxis. Eur Neurol,58(4):215-7 (2007).
  • Winter AC, Hoffmann W, Meisinger C, Evers S, Vennemann M, Pfaffenrath V, et al. As- sociation between lifestyle factors and headache. J Headache Pain,12(2):147-55 (2011).
  • Skomo ML, Desselle SP, Shah N. Development and construct validation of the pharma- cists’ care of migraineurs scale. Headache,49(1):54-63 (2009).
  • Wenzel RG, Schommer JC, Marks TG. Morbidity and medication preferences of individ- uals with headache presenting to a community pharmacy. Headache,44(1):90-4 (2004).
  • Desselle SP, Skomo ML. Factors related to pharmacists’ care of migraineurs. Research in Social & Administrative Pharmacy : RSAP,6(3):232-45 (2010).
  • Atasoy HT, Unal AE, Atasoy N, Emre U, Sumer M. Low income and education levels may cause medication overuse and chronicity in migraine patients. Headache,45(1):25-31
  • Diener HC, Dowson A, Whicker S, Bacon T. Development and validation of a pharmacy migraine questionnaire to assess suitability for treatment with a triptan. J Headache Pain,9(6):359-65 (2008).
  • Hoffmann W, Herzog B, Muhlig S, Kayser H, Fabian R, Thomsen M, et al. Pharmaceuti- cal care for migraine and headache patients: a community-based, randomized inter- vention. The Annals of Pharmacotherapy,42(12):1804-13 (2008).
  • Sondergaard J, Foged A, Kragstrup J, Gaist D, Gram LF, Sindrup SH, et al. Inten- sive community pharmacy intervention had little impact on triptan consumption: a randomized controlled trial. Scandinavian Journal of Primary Health Care,24(1):16-21 (2006).
  • Gahir KK, Larner AJ. What role do community pharmacists currently play in the man- agement of headache? A hospital-based perspective. International Journal of Clinical Practice,58(3):257-9 (2004).
  • Wenzel R. Headache beyond the “physician-centric” model. Headache,48(9):1377-8 (2008).

An approach to headache in primary care settings: the pharmacist’s role

Year 2013, Issue: 1, 75 - 104, 01.01.2013

Abstract

Primary headaches are among common causes of chronic pain which can affect great portions of the society regardless of age, gender, socioeconomic status and education. Although successful pain management can be achieved by the use of basic analgesic and nonsteroidal antiinfammatory drugs especially in the treatment of acute attacks, inadequate knowledge or misperceptions about the different types of headaches in the society may lead to inappropriate and unnecessary drug use which results in longer duration of pain and decreased effectiveness of therapy. The use of triptans beyond the recommended dose and frequency for attacks results in an increased frequency of side effects and may lead to medication overuse headache. Patients’ misunderstanding of treatment principles of adjuvant analgesics in long term use makes optimisation of drug therapy difficult and reduces quality of life. An identification of drug therapy problems, counseling and early referrals to the secondary care specialist by the pharmacist, whom are known as a ‘first call point’ by most patients, may minimise unnecessary drug use and related unwanted socio-economic problems. Therefore, maintaining the link between primary and secondary health care providers will enhance the success of pain management. In order to establish the communication pathways and multidisciplinary team work in a health system, the role and the responsibilities of the pharmacist should be acknowledged by other health care professionals and required infrastructures and practices should be provided.

References

  • Baykan B, Ertas M, Karli N, Akat-Aktas S, Uzunkaya O, Zarifoglu M, et al.: The burden of headache in neurology outpatient clinics in Turkey. Pain Pract,7(4):313-23 (2007).
  • Goadsby PJ. Recent advances in the diagnosis and management of migraine. BMJ, 332(7532):25-9 (2006).
  • Mueller LL. Diagnosing and managing migraine headache. J Am Osteopath Assoc, 107(10 Suppl 6):ES10-6 (2007).
  • Loder E, Rizzoli P.: Tension-type headache. BMJ, 336(7635):88-92 (2008).
  • Turkdogan D, Cagirici S, Soylemez D, Sur H, Bilge C, Turk U. Characteristic and overlap- ping features of migraine and tension-type headache. Headache , 46(3):461-8 (2006).
  • Hershey AD, Winner P, Kabbouche MA, Powers SW. Headaches. Curr Opin Pedi- atr,19(6):663-9 (2007).
  • MacGregor E A, Steiner T J, G DPT. Guidelines for All Healthcare Professionals in the Di- agnosis and Management of Migraine, Tension-Type, Cluster and Medication-Overuse Headache, British Association for the Study of Headache (BASH) Guideline. 2010.
  • Buse DC, Rupnow MF, Lipton RB. Assessing and managing all aspects of migraine: mi- graine attacks, migraine-related functional impairment, common comorbidities, and quality of life. Mayo Clinic proceedings. Mayo Clinic,84(5):422-35 (2009).
  • Stovner LJ, Andree C. Prevalence of headache in Europe: a review for the Eurolight proj- ect. J Headache Pain, 11(4):289-99 (2010).
  • Koseoglu E, Nacar M, Talaslioglu A, Cetinkaya F. Epidemiological and clinical charac- teristics of migraine and tension type headache in 1146 females in Kayseri, Turkey. Cephalalgia, 23(5):381-8 (2003).
  • Kececi H, Dener S. Epidemiological and clinical characteristics of migraine in Sivas, Turkey. Headache, 42(4):275-80 (2002).
  • Aygul R, Deniz O, Kocak N, Orhan A, Ulvi H. The clinical properties of a migrainous population in eastern Turkey-Erzurum. Southern Medical Journal, 98(1):23-7 (2005).
  • Ertas M, Siva A, Dalkara T, Uzuner N, Dora B, Inan L, et al. Validity and reliability of the Turkish Migraine Disability Assessment (MIDAS) questionnaire. Headache, 44(8):786- 93 (2004).
  • Kutlu A, Yaluğ İ, Mülayim S, Temel Obuz E, Selekler M. Trigger factors of migraine. Nöropsikiyatri Arşivi,47:58-63 (2010).
  • Bag B, Karabulut N. Pain-relieving factors in migraine and tension-type headache. In- ternational Journal of Clinical Practice, 59(7):760-3 (2005).
  • Karli N, Zarifoglu M, Calisir N, Akgoz S. Comparison of pre-headache phases and trigger factors of migraine and episodic tension-type headache: do they share similar clinical pathophysiology? Cephalalgia, 25(6):444-51 (2005).
  • Ertas M, Baykan B, Kocasoy Orhan E, Zarifoglu M, Karli N, Saip S, et al. One-year prev- alence and the impact of migraine and tension-type headache in Turkey: a nationwide home-based study in adults. J Headache Pain,13:147-57 (2012).
  • Steiner TJ, Paemeleire K, Jensen R, Valade D, Savi L, Lainez MJ, et al. European prin- ciples of management of common headache disorders in primary care. J Headache Pain, 8 Suppl 1:S3-47 (2007).
  • Thomas E, Boardman HF, Ogden H, Millson DS, Croft PR. Advice and care for head- aches: who seeks it, who gives it? Cephalalgia,24(9):740-52 (2004).
  • Wenzel RG, Lipton RB, Diamond ML, Cady R. Migraine therapy: a survey of pharmacists’ knowledge, attitudes, and practice patterns. Headache, 45(1):47-52 (2005).
  • Harpole LH, Samsa GP, Matchar DB, Silberstein SD, Blumenfeld A, Jurgelski AE. Bur- den of illness and satisfaction with care among patients with headache seen in a pri- mary care setting. Headache, 45(8):1048-55 (2005).
  • Tellez-Zenteno JF. Economic impact of primary headaches. J Headache Pain,7(2):57-9 (2006).
  • Karli N, Zarifoglu M, Ertaş M, Saip S, Ozturk V, Bicakci S, et al. Economic impact of primary headaches in Turkey: a university hospital based study: part II. J Headache Pain,7(2):75-82 (2006).
  • Selekler HM, Komsuoglu S. Unconventional treatment methods in Turkish migraine sufferers. J Headache Pain,5:197-200 (2004).
  • Gedikoglu U, Coskun O, Inan LE, Ucler S, Tunc T, Emre U. Validity and reliability of Turkish translation of Migraine Disability Assessment (MIDAS) questionnaire in pa- tients with migraine. Cephalalgia, 25(6):452-6 (2005).
  • Gedikoglu U, Ucler S, Inan LE, Coskun O, Tunc T. A preliminary study: validity and reli- ability of Turkish translation of migraine disability assessment (MIDAS) questionnaire in Turkish patients with chronic tension type headache. The International Journal of Neuroscience,116(11):1337-45 (2006).
  • Jensen R, Tassorelli C, Rossi P, Allena M, Osipova V, Steiner T, et al. A basic diagnostic headache diary (BDHD) is well accepted and useful in the diagnosis of headache. a multicentre European and Latin American study. Cephalalgia,31(15):1549-60 (2011).
  • Evers S, Afra J, Frese A, Goadsby PJ, Linde M, May A, et al. EFNS guideline on the drug treatment of migraine - report of an EFNS task force. European journal of neurology : the official journal of the European Federation of Neurological Societies,13(6):560-72 (2006).
  • Evers S, Afra J, Frese A, Goadsby PJ, Linde M, May A, et al. EFNS guideline on the drug treatment of migraine--revised report of an EFNS task force. European journal of neurology : the official journal of the European Federation of Neurological Societies, 16(9):968-81 (2009).
  • MacGregor EA, Steiner TJ, Davies PTG. Guidelines for All Healthcare Professionals in the Diagnosis and Management of Migraine, Tension-Type, Cluster and Medication- Overuse Headache. 3rd Edition ed: The British Association for the Study of Headache, 2010.
  • Türk Nöroloji Derneği: Başağrısı Tanı ve Tedavi Rehberi (2011 Güncelleşmiş şekli) In: Erdemoğlu AK (ed), Türk Nöroloji Derneği,1-56 (2011).
  • Pesaturo K, Wooding F. Modern management of the migraine headache. American Jour- nal of Lifestyle Medicine,3:147-59 (2009).
  • MacGregor E A, Steiner T J, G DPT. Guidelines for All Healthcare Professionals in the Diagnosis and Management of Migraine, Tension-Type, Cluster and Medication- Overuse Headache. 3rd edition (1st revision) ed: British Association for the Study of Headache, 2010.
  • Derry S, Moore RA, McQuay HJ. Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults. Cochrane Database Syst Rev (11):CD008040 (2010).
  • Kirthi V, Derry S, Moore RA, McQuay HJ. Aspirin with or without an antiemetic for acute migraine headaches in adults. Cochrane Database Syst Rev (4):CD008041 (2010).
  • Rabbie R, Derry S, Moore RA, McQuay HJ. Ibuprofen with or without an antiemetic for acute migraine headaches in adults. Cochrane Database Syst Rev (10):CD008039 (2010).
  • Derry S, Rabbie R, Moore RA. Diclofenac with or without an antiemetic for acute mi- graine headaches in adults. Cochrane Database Syst Rev,2:CD008783 (2012).
  • Bendtsen L, Jensen R. Treating tension-type headache -- an expert opinion. Expert Opinion on Pharmacotherapy,12(7):1099-109 (2011).
  • Lampl C, Voelker M, Steiner TJ. Aspirin is first-line treatment for migraine and episodic tension-type headache regardless of headache intensity. Headache,52(1):48-56 (2012).
  • Mett A, Tfelt-Hansen P. Acute migraine therapy: recent evidence from randomized com- parative trials. Current Opinion in Neurology,21(3):331-7 (2008).
  • Holland S, Silberstein SD, Freitag F, Dodick DW, Argoff C, Ashman E. Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology,78(17):1346-53 (2012).
  • Tepper S, Allen C, Sanders D, Greene A, Boccuzzi S. Coprescription of triptans with potentially interacting medications: a cohort study involving 240,268 patients. Head- ache,43(1):44-8 (2003).
  • Ferrari A, Sternieri E, Ferraris E, Bertolini A. Emerging problems in the pharmacology of migraine: interactions between triptans and drugs for prophylaxis. Pharmacological research : the official journal of the Italian Pharmacological Society,48(1):1-9 (2003).
  • Loder E. Triptan therapy in migraine. The New England Journal of Medicine,363(1):63-70 (2010).
  • Dowson AJ, Tepper SJ, Dahlof C. Patients’ preference for triptans and other medica- tions as a tool for assessing the efficacy of acute treatments for migraine. J Headache Pain, 6(3):112-20 (2005).
  • Gallagher RM, Kunkel R. Migraine medication attributes important for patient compli- ance: concerns about side effects may delay treatment. Headache,43(1):36-43 (2003).
  • Mullins CD, Weis KA, Perfetto EM, Subedi PR, Healey PJ. Triptans for migraine therapy: a comparison based on number needed to treat and doses needed to treat. Journal of Managed Care Pharmacy : JMCP,11(5):394-402 (2005).
  • Ferrari MD, Roon KI, Lipton RB, Goadsby PJ. Oral triptans (serotonin 5-HT(1B/1D) agonists) in acute migraine treatment: a meta-analysis of 53 trials. Lan- cet,358(9294):1668-75 (2001).
  • Culley EJ. Which is more elusive, the pot of gold at the end of a rainbow or determining the most cost-effective triptan? Journal of Managed Care Pharmacy : JMCP,11(6):513-5 (2005).
  • Whyte C, Tepper SJ, Evans RW. Expert opinion: Rescue me: rescue medication for mi- graine. Headache,50(2):307-13 (2010).
  • Diamond ML, Wenzel RG, Nissan GR. Optimizing migraine therapy: evidence-based and patient-centered care. Expert Review of Neurotherapeutics,6(6):911-9 (2006).
  • Rapoport AM. New acute treatments for headache. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiol- ogy,31 Suppl 1:S129-32 (2010).
  • Evers S. Treatment of migraine with prophylactic drugs. Expert Opinion on Pharmaco- therapy,9(15):2565-73 (2008).
  • Whyte CA, Tepper SJ. Adverse effects of medications commonly used in the treatment of migraine. Expert Review of Neurotherapeutics,9(9):1379-91 (2009).
  • Antonaci F, Dumitrache C, De Cillis I, Allena M. A review of current European treatment guidelines for migraine. J Headache Pain,11(1):13-9 (2010).
  • Gales BJ, Bailey EK, Reed AN, Gales MA. Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for the prevention of migraines. The Annals of Pharmaco- therapy,44(2):360-6 (2010).
  • D’Amico D, Tepper SJ. Prophylaxis of migraine: general principles and patient accep- tance. Neuropsychiatric Disease and Treatment, 4(6):1155-67 (2008).
  • Evans RW, Rizzoli P, Loder E, Bana D. Beta-blockers for migraine. Headache,48(3):455-60 (2008).
  • Jackson JL, Shimeall W, Sessums L, Dezee KJ, Becher D, Diemer M, et al. Tricyclic antidepressants and headaches: systematic review and meta-analysis. BMJ,341:c5222
  • Moja PL, Cusi C, Sterzi RR, Canepari C. Selective serotonin re-uptake inhibitors (SS- RIs) for preventing migraine and tension-type headaches. Cochrane Database Syst Rev (3):CD002919 (2005).
  • Krishnan A, Silver N. Headache (chronic tension-type). BMJ Clinical Evidence (Online), 3-40 (2009).
  • Dodick DW, Freitag F, Banks J, Saper J, Xiang J, Rupnow M, et al. Topiramate ver- sus amitriptyline in migraine prevention: a 26-week, multicenter, randomized, double- blind, double-dummy, parallel-group noninferiority trial in adult migraineurs. Clinical Therapeutics,31(3):542-59 (2009).
  • Adelman J, Freitag FG, Lainez M, Shi Y, Ascher S, Mao L, et al. Analysis of safety and tolerability data obtained from over 1,500 patients receiving topiramate for migraine prevention in controlled trials. Pain Med,9(2):175-85 (2008).
  • Edvinsson L, Linde M. New drugs in migraine treatment and prophylaxis: telcagepant and topiramate. Lancet,376(9741):645-55 (2010).
  • Bussone G, Diener HC, Pfeil J, Schwalen S. Topiramate 100 mg/day in migraine pre- vention: a pooled analysis of double-blind randomised controlled trials. International Journal of Clinical Practice,59(8):961-8 (2005).
  • Ferrari A, Tiraferri I, Neri L, Sternieri E. Clinical pharmacology of topiramate in mi- graine prevention. Expert Opinion on Drug Metabolism & Toxicology,7(9):1169-81 (2011).
  • Keskinbora K, Aydinli I. A double-blind randomized controlled trial of topiramate and amitriptyline either alone or in combination for the prevention of migraine. Clinical Neurology and Neurosurgery,110(10):979-84 (2008).
  • Bulut S, Berilgen MS, Baran A, Tekatas A, Atmaca M, Mungen B. Venlafaxine ver- sus amitriptyline in the prophylactic treatment of migraine: randomized, double-blind, crossover study. Clinical Neurology and Neurosurgery,107(1):44-8 (2004).
  • Mulleners WM, Chronicle EP. Anticonvulsants in migraine prophylaxis: a Cochrane review. Cephalalgia,28(6):585-97 (2008).
  • Afshari D, Rafizadeh S, Rezaei M. A comparative study of the effects of low-dose topi- ramate versus sodium valproate in migraine prophylaxis. The International Journal of Neuroscience,122(2):60-8 (2012).
  • Yurekli VA, Akhan G, Kutluhan S, Uzar E, Koyuncuoglu HR, Gultekin F. The effect of so- dium valproate on chronic daily headache and its subgroups. J Headache Pain,9(1):37- 41 (2008).
  • Krymchantowski AV, Jevoux Cda C. Low-dose topiramate plus sodium divalproate for positive responders intolerant to full-dose monotherapy. Headache,52(1):129-32 (2012).
  • Ergun H, Gulmez SE, Tulunay FC. Cost-minimization analysis comparing topiramate with standard treatments in migraine prophylaxis. Eur Neurol,58(4):215-7 (2007).
  • Winter AC, Hoffmann W, Meisinger C, Evers S, Vennemann M, Pfaffenrath V, et al. As- sociation between lifestyle factors and headache. J Headache Pain,12(2):147-55 (2011).
  • Skomo ML, Desselle SP, Shah N. Development and construct validation of the pharma- cists’ care of migraineurs scale. Headache,49(1):54-63 (2009).
  • Wenzel RG, Schommer JC, Marks TG. Morbidity and medication preferences of individ- uals with headache presenting to a community pharmacy. Headache,44(1):90-4 (2004).
  • Desselle SP, Skomo ML. Factors related to pharmacists’ care of migraineurs. Research in Social & Administrative Pharmacy : RSAP,6(3):232-45 (2010).
  • Atasoy HT, Unal AE, Atasoy N, Emre U, Sumer M. Low income and education levels may cause medication overuse and chronicity in migraine patients. Headache,45(1):25-31
  • Diener HC, Dowson A, Whicker S, Bacon T. Development and validation of a pharmacy migraine questionnaire to assess suitability for treatment with a triptan. J Headache Pain,9(6):359-65 (2008).
  • Hoffmann W, Herzog B, Muhlig S, Kayser H, Fabian R, Thomsen M, et al. Pharmaceuti- cal care for migraine and headache patients: a community-based, randomized inter- vention. The Annals of Pharmacotherapy,42(12):1804-13 (2008).
  • Sondergaard J, Foged A, Kragstrup J, Gaist D, Gram LF, Sindrup SH, et al. Inten- sive community pharmacy intervention had little impact on triptan consumption: a randomized controlled trial. Scandinavian Journal of Primary Health Care,24(1):16-21 (2006).
  • Gahir KK, Larner AJ. What role do community pharmacists currently play in the man- agement of headache? A hospital-based perspective. International Journal of Clinical Practice,58(3):257-9 (2004).
  • Wenzel R. Headache beyond the “physician-centric” model. Headache,48(9):1377-8 (2008).
There are 83 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Aygin Bayraktar-ekincioğlu This is me

Kutay Demirkan This is me

Publication Date January 1, 2013
Published in Issue Year 2013 Issue: 1

Cite

Vancouver Bayraktar-ekincioğlu A, Demirkan K. Birinci Basamak Tedavi Hizmetlerinde Baş Ağrılarına Yaklaşım: Eczacının Rolü. HUJPHARM. 2013(1):75-104.