EN
Recurrent miscarriages in a couple with t(4,8) and inv (9)
Abstract
Nearly 60% of all first trimester spontaneous miscarriages are due to chromosomal abnormalities.
The most frequent are numerical abnormalities (94%), followed by structural abnormalities(5%)
and less frequently mosaicsm(1%).
We report a 28 years-old couple in which an 4,8 translocation and 9 inversion has been identified
during the investigation for recurrent miscarriages.They were phenotypically normal female and
male. She had suffered four miscarriages in 7 years but no cytogenetic analyses had been
performed in these abortuses.
In karyotyping by standard G-banding techniques of peripheral blood cultures showed 46,XY,t(4,8)
and 46,XX,inv (9). The translocation was also confirmed by FISH studies.We conclude that
cytogenetic analysis should be an integral part of etiological exploration in couples with recurrent
abortions
Keywords
Details
Primary Language
English
Subjects
-
Journal Section
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Publication Date
December 1, 2011
Submission Date
December 1, 2011
Acceptance Date
-
Published in Issue
Year 2011 Volume: 2 Number: 2
APA
Oral, D., Türkyılmaz, A., & Simsek, S. (2011). Recurrent miscarriages in a couple with t(4,8) and inv (9). International Archives of Medical Research, 2(2), 60-65. https://izlik.org/JA75HJ45AE
AMA
1.Oral D, Türkyılmaz A, Simsek S. Recurrent miscarriages in a couple with t(4,8) and inv (9). IAMR. 2011;2(2):60-65. https://izlik.org/JA75HJ45AE
Chicago
Oral, Diclehan, Ayşegül Türkyılmaz, and Selda Simsek. 2011. “Recurrent Miscarriages in a Couple With T(4,8) and Inv (9)”. International Archives of Medical Research 2 (2): 60-65. https://izlik.org/JA75HJ45AE.
EndNote
Oral D, Türkyılmaz A, Simsek S (December 1, 2011) Recurrent miscarriages in a couple with t(4,8) and inv (9). International Archives of Medical Research 2 2 60–65.
IEEE
[1]D. Oral, A. Türkyılmaz, and S. Simsek, “Recurrent miscarriages in a couple with t(4,8) and inv (9)”, IAMR, vol. 2, no. 2, pp. 60–65, Dec. 2011, [Online]. Available: https://izlik.org/JA75HJ45AE
ISNAD
Oral, Diclehan - Türkyılmaz, Ayşegül - Simsek, Selda. “Recurrent Miscarriages in a Couple With T(4,8) and Inv (9)”. International Archives of Medical Research 2/2 (December 1, 2011): 60-65. https://izlik.org/JA75HJ45AE.
JAMA
1.Oral D, Türkyılmaz A, Simsek S. Recurrent miscarriages in a couple with t(4,8) and inv (9). IAMR. 2011;2:60–65.
MLA
Oral, Diclehan, et al. “Recurrent Miscarriages in a Couple With T(4,8) and Inv (9)”. International Archives of Medical Research, vol. 2, no. 2, Dec. 2011, pp. 60-65, https://izlik.org/JA75HJ45AE.
Vancouver
1.Diclehan Oral, Ayşegül Türkyılmaz, Selda Simsek. Recurrent miscarriages in a couple with t(4,8) and inv (9). IAMR [Internet]. 2011 Dec. 1;2(2):60-5. Available from: https://izlik.org/JA75HJ45AE