Endoscopic Approach a Rare Adult Nasal Glioma and Review of the Literature

Abstract

Nasal gliomas are rare, benign, congenital tumors that are throught to be the result of abnormality in embryonic development. Three types of clinical presentations have been recognized; extranasal, intranasal and combined. Clinically, these masses are non-pulsatile, gray or purple lesions that obstruct the nasal cavity and can lead to various complications. Histologically, they consist of astrocytic cells, fibrous and vascular connective tissue covered with nasal respiratory mucosa. Treatment of nasal glioma requires a multidisciplinary approach including a radiologist, neurosurgeon and otorhinolaryngologist. Radiological investigation should be performed to determine intracranial extension. This report describes a 60-year-old male undergoing endoscopy for nasal mass and postoperative pathology presenting as nasal glioma. To the best of our knowledge there are few published reports of adult glioma arising from the nasal cavity. The mass was excised totally using an endoscopic approach. We describe the clinical and histopathological features of this rare lesion, with a complete review of the relevant literature.

Keywords

• Nasal glioma, embryonic development, Nasal mass

References

1. Hughes G, Sharpino G, Hunt W, Tucker H. Management of the congenital midline nasal mass: a review. Head Neck Surg 1980; 2: 222–33.
2. Katz A, Lewis JS.Nasal gliomas. Arch Otolaryngol 1971; 94:351–5.
3. Jaffe BF Classification and management of anomalies of the nose. Otolaryngol Clin North Am 1981; 14: 989–1004.
4. Paller AS, Pensler JM, Tomita T. Nasal midline masses in infants and children. Arch Dermatol1991; 127: 362-6.
5. G. Altissimi, S. Ascani, S. Falcetti, C. Cazzato, I. Bravi. Central nervous system tissue heterotopia of the nose: case report and review of the literatureliwal. ACTA otorhinolaryngologica italica 2009;29: 218-21.
6. M K.Kasliwal, VK. Anand, E.Lavi, T H. Schwartz Endoscopic Management of a Rare Case of Nasal Glioma in Meckel ’ s Cave in an Adult: Case Report. Minim Invas Neurosurg; 2010 53: 191 – 3.
7. K R. Smith JR, HG. Schwartz, SA Luse, and JH Ogura. Nasal Gliomas: A Report of Five Cases with Electron Microscopy of One. J Neurosurg1963; 20: 968-82.
8. Pasquini E, Farneti G, Giausa G, Biavati M. A rare case of nasal glioma in adult age. Otolaryngol Head Neck Surg ;118(6):905-6. Y Ducic. Case Reports Nasal Gliomas. The Journal of Otolaryngology 1999; 28(5): 285.

9. MT Tetzlaff, P Liu, B W O’Malley, J Virginia A Livolsi, D Elderi . Report of a case of Sinonasal undifferentiated carsinoma arising in a background of extensive nasal gliomatozis. Head & Neck 2008; 30(4):549-55.
10. A Majithia, S H Liyanage, R Hewitt, W E Grant. Adult nasal glioma presenting with visual loss. The Journal of Laryngology & Otology 2010; 124, 1309–13.
11. Pollard K, Carter DA. A case of nasal glioma and neurofibromatosis. A new association. J Laryngol Otol 1987; 101 (5):497-9.
12. Chau HN, Hopkins C, McGilligan A. A rare case of nasal glioma in the sphenoid sinus of an adult presenting with meningoencephalitis. Eur Arch Otorhinolaryngol 2005; 262 (7):592-4.
13. Jain RK, Shukla PK, Aryya NC, Srivastava A, Kumar S. Nasal glioma presenting as blindness in an adult. Ann Ophthalmol 2001; 33:67–9.
14. Ogura JH, Schenck NL. Unusual nasal tumours. Otolaryngol Clin North Am1973; 6: 813–73.
15. Bradley PJ, Singh SD. Nasal glioma. J Laryngol Otol 1985; 99:247–52.
16. Verney Y, Zanolla G, Teixeira R, Oliveira LC. Midline nasal mass in infancy: a nasal gliom case report. Eur J Pediatr Surg 2001; 11: 324-7.
17. Burckhardt W, Tobon D. Endoscopic approaches to nasal glioma. Otolaryngtol Head Neck Surg1999; 10: 747–8.