Nasal gliomas are rare, benign, congenital tumors that are throught to be the result of abnormality
in embryonic development. Three types of clinical presentations have been recognized; extranasal,
intranasal and combined. Clinically, these masses are non-pulsatile, gray or purple lesions that
obstruct the nasal cavity and can lead to various complications. Histologically, they consist of
astrocytic cells, fibrous and vascular connective tissue covered with nasal respiratory mucosa.
Treatment of nasal glioma requires a multidisciplinary approach including a radiologist,
neurosurgeon and otorhinolaryngologist. Radiological investigation should be performed to
determine intracranial extension. This report describes a 60-year-old male undergoing endoscopy
for nasal mass and postoperative pathology presenting as nasal glioma.
To the best of our knowledge there are few published reports of adult glioma arising from the nasal
cavity. The mass was excised totally using an endoscopic approach.
We describe the clinical and histopathological features of this rare lesion, with a complete review
of the relevant literature.
Hughes G, Sharpino G, Hunt W, Tucker H. Management of the congenital midline nasal mass: a review. Head Neck Surg 1980; 2: 222–33.
Katz A, Lewis JS.Nasal gliomas. Arch Otolaryngol 1971; 94:351–5.
Jaffe BF Classification and management of anomalies of the nose. Otolaryngol Clin North Am 1981; 14: 989–1004.
Paller AS, Pensler JM, Tomita T. Nasal midline masses in infants and children. Arch Dermatol1991; 127: 362-6.
G. Altissimi, S. Ascani, S. Falcetti, C. Cazzato, I. Bravi. Central nervous system tissue heterotopia of the nose: case report and review of the literatureliwal. ACTA otorhinolaryngologica italica 2009;29: 218-21.
M K.Kasliwal, VK. Anand, E.Lavi, T H. Schwartz Endoscopic Management of a Rare Case of Nasal Glioma in Meckel ’ s Cave in an Adult: Case Report. Minim Invas Neurosurg; 2010 53: 191 – 3.
K R. Smith JR, HG. Schwartz, SA Luse, and JH Ogura. Nasal Gliomas: A Report of Five Cases with Electron Microscopy of One. J Neurosurg1963; 20: 968-82.
Pasquini E, Farneti G, Giausa G, Biavati M. A rare case of nasal glioma in adult age. Otolaryngol Head Neck Surg ;118(6):905-6. Y Ducic. Case Reports Nasal Gliomas. The Journal of Otolaryngology 1999; 28(5): 285.
MT Tetzlaff, P Liu, B W O’Malley, J Virginia A Livolsi, D Elderi . Report of a case of Sinonasal undifferentiated carsinoma arising in a background of extensive nasal gliomatozis. Head & Neck 2008; 30(4):549-55.
A Majithia, S H Liyanage, R Hewitt, W E Grant. Adult nasal glioma presenting with visual loss. The Journal of Laryngology & Otology 2010; 124, 1309–13.
Pollard K, Carter DA. A case of nasal glioma and neurofibromatosis. A new association. J Laryngol Otol 1987; 101 (5):497-9.
Chau HN, Hopkins C, McGilligan A. A rare case of nasal glioma in the sphenoid sinus of an adult presenting with meningoencephalitis. Eur Arch Otorhinolaryngol 2005; 262 (7):592-4.
Jain RK, Shukla PK, Aryya NC, Srivastava A, Kumar S. Nasal glioma presenting as blindness in an adult. Ann Ophthalmol 2001; 33:67–9.
Hughes G, Sharpino G, Hunt W, Tucker H. Management of the congenital midline nasal mass: a review. Head Neck Surg 1980; 2: 222–33.
Katz A, Lewis JS.Nasal gliomas. Arch Otolaryngol 1971; 94:351–5.
Jaffe BF Classification and management of anomalies of the nose. Otolaryngol Clin North Am 1981; 14: 989–1004.
Paller AS, Pensler JM, Tomita T. Nasal midline masses in infants and children. Arch Dermatol1991; 127: 362-6.
G. Altissimi, S. Ascani, S. Falcetti, C. Cazzato, I. Bravi. Central nervous system tissue heterotopia of the nose: case report and review of the literatureliwal. ACTA otorhinolaryngologica italica 2009;29: 218-21.
M K.Kasliwal, VK. Anand, E.Lavi, T H. Schwartz Endoscopic Management of a Rare Case of Nasal Glioma in Meckel ’ s Cave in an Adult: Case Report. Minim Invas Neurosurg; 2010 53: 191 – 3.
K R. Smith JR, HG. Schwartz, SA Luse, and JH Ogura. Nasal Gliomas: A Report of Five Cases with Electron Microscopy of One. J Neurosurg1963; 20: 968-82.
Pasquini E, Farneti G, Giausa G, Biavati M. A rare case of nasal glioma in adult age. Otolaryngol Head Neck Surg ;118(6):905-6. Y Ducic. Case Reports Nasal Gliomas. The Journal of Otolaryngology 1999; 28(5): 285.
MT Tetzlaff, P Liu, B W O’Malley, J Virginia A Livolsi, D Elderi . Report of a case of Sinonasal undifferentiated carsinoma arising in a background of extensive nasal gliomatozis. Head & Neck 2008; 30(4):549-55.
A Majithia, S H Liyanage, R Hewitt, W E Grant. Adult nasal glioma presenting with visual loss. The Journal of Laryngology & Otology 2010; 124, 1309–13.
Pollard K, Carter DA. A case of nasal glioma and neurofibromatosis. A new association. J Laryngol Otol 1987; 101 (5):497-9.
Chau HN, Hopkins C, McGilligan A. A rare case of nasal glioma in the sphenoid sinus of an adult presenting with meningoencephalitis. Eur Arch Otorhinolaryngol 2005; 262 (7):592-4.
Jain RK, Shukla PK, Aryya NC, Srivastava A, Kumar S. Nasal glioma presenting as blindness in an adult. Ann Ophthalmol 2001; 33:67–9.
Akdag, M., Alabalik, U., Dusak, A., Aguloglu, B. (2013). Endoscopic Approach a Rare Adult Nasal Glioma and Review of the Literature. International Archives of Medical Research, 5(2), 15-21.
AMA
Akdag M, Alabalik U, Dusak A, Aguloglu B. Endoscopic Approach a Rare Adult Nasal Glioma and Review of the Literature. IAMR. December 2013;5(2):15-21.
Chicago
Akdag, Mehmet, Ulaş Alabalik, Abdurrahim Dusak, and Bülent Aguloglu. “Endoscopic Approach a Rare Adult Nasal Glioma and Review of the Literature”. International Archives of Medical Research 5, no. 2 (December 2013): 15-21.
EndNote
Akdag M, Alabalik U, Dusak A, Aguloglu B (December 1, 2013) Endoscopic Approach a Rare Adult Nasal Glioma and Review of the Literature. International Archives of Medical Research 5 2 15–21.
IEEE
M. Akdag, U. Alabalik, A. Dusak, and B. Aguloglu, “Endoscopic Approach a Rare Adult Nasal Glioma and Review of the Literature”, IAMR, vol. 5, no. 2, pp. 15–21, 2013.
ISNAD
Akdag, Mehmet et al. “Endoscopic Approach a Rare Adult Nasal Glioma and Review of the Literature”. International Archives of Medical Research 5/2 (December2013), 15-21.
JAMA
Akdag M, Alabalik U, Dusak A, Aguloglu B. Endoscopic Approach a Rare Adult Nasal Glioma and Review of the Literature. IAMR. 2013;5:15–21.
MLA
Akdag, Mehmet et al. “Endoscopic Approach a Rare Adult Nasal Glioma and Review of the Literature”. International Archives of Medical Research, vol. 5, no. 2, 2013, pp. 15-21.
Vancouver
Akdag M, Alabalik U, Dusak A, Aguloglu B. Endoscopic Approach a Rare Adult Nasal Glioma and Review of the Literature. IAMR. 2013;5(2):15-21.
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