Böbrek naklinde kullanılan immünsüpresif tedaviler

Emin Taşkıran; Oytun Erbaş; Harun Akar

doi:10.5606/fng.transplantasyon.2016.009

Böbrek naklinde kullanılan immünsüpresif tedaviler

Abstract

Böbrek nakli sonrası, indüksiyon immünsüpresyon tedavisi için konvansiyonel immünsüpresif tedavi yerine yeni keşfedilen antikorlarla kombine edilmiş standart immünsüpresif tedavi önerilmektedir. Bu ajanlar, anti-lenfosit antikorları (rATG, atgam, alemtuzumab), interlökin 2 reseptör antagonistlerini (basiliksimab), anti-CD20 antikorları (rituksimab) içermektedir. İdame immünsüpresyon tedavisi ise akut rejeksiyonu ve allogreft kaybını, önlemek için gereklidir. Bu ajanlar kalsinörin inhibitörlerini (siklosporin, tacrolimus), kortikosteroidleri (prednizon), antimetabolitleri (azatiyopürin ve MMF), mTOR inhibitörlerini (sirolimus) ve belatacepti içermektedir. Tüm rejimlerin etki ve yan etkileri yapılan çalışmaların ışığında tartışılacaktır.

Keywords

Böbrek nakli,immünsüpresif ajanlar,immünsüpresif antikor

References

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Details

Primary Language

Turkish

Subjects

-

Journal Section

Research Article

Authors

Emin Taşkıran

Oytun Erbaş

Harun Akar This is me

Publication Date

February 1, 2016

Submission Date

November 1, 2016

Acceptance Date

-

Published in Issue

Year 2016 Volume: 1 Number: 1

DOI

https://doi.org/10.5606/fng.transplantasyon.2016.009

IZ

https://izlik.org/JA69JP68TH

Cite

RIS / Bibtex

APA

Taşkıran, E., Erbaş, O., & Akar, H. (2016). Böbrek naklinde kullanılan immünsüpresif tedaviler. İstanbul Bilim Üniversitesi Florence Nightingale Transplantasyon Dergisi, 1(1), 48-52. https://doi.org/10.5606/fng.transplantasyon.2016.009

AMA

1.Taşkıran E, Erbaş O, Akar H. Böbrek naklinde kullanılan immünsüpresif tedaviler. İstanbul Bilim Üniversitesi Florence Nightingale Transplantasyon Dergisi. 2016;1(1):48-52. doi:10.5606/fng.transplantasyon.2016.009

Chicago

Taşkıran, Emin, Oytun Erbaş, and Harun Akar. 2016. “Böbrek Naklinde Kullanılan Immünsüpresif Tedaviler”. İstanbul Bilim Üniversitesi Florence Nightingale Transplantasyon Dergisi 1 (1): 48-52. https://doi.org/10.5606/fng.transplantasyon.2016.009.

EndNote

Taşkıran E, Erbaş O, Akar H (February 1, 2016) Böbrek naklinde kullanılan immünsüpresif tedaviler. İstanbul Bilim Üniversitesi Florence Nightingale Transplantasyon Dergisi 1 1 48–52.

IEEE

[1]E. Taşkıran, O. Erbaş, and H. Akar, “Böbrek naklinde kullanılan immünsüpresif tedaviler”, İstanbul Bilim Üniversitesi Florence Nightingale Transplantasyon Dergisi, vol. 1, no. 1, pp. 48–52, Feb. 2016, doi: 10.5606/fng.transplantasyon.2016.009.

ISNAD

Taşkıran, Emin - Erbaş, Oytun - Akar, Harun. “Böbrek Naklinde Kullanılan Immünsüpresif Tedaviler”. İstanbul Bilim Üniversitesi Florence Nightingale Transplantasyon Dergisi 1/1 (February 1, 2016): 48-52. https://doi.org/10.5606/fng.transplantasyon.2016.009.

JAMA

1.Taşkıran E, Erbaş O, Akar H. Böbrek naklinde kullanılan immünsüpresif tedaviler. İstanbul Bilim Üniversitesi Florence Nightingale Transplantasyon Dergisi. 2016;1:48–52.

MLA

Taşkıran, Emin, et al. “Böbrek Naklinde Kullanılan Immünsüpresif Tedaviler”. İstanbul Bilim Üniversitesi Florence Nightingale Transplantasyon Dergisi, vol. 1, no. 1, Feb. 2016, pp. 48-52, doi:10.5606/fng.transplantasyon.2016.009.

Vancouver

1.Emin Taşkıran, Oytun Erbaş, Harun Akar. Böbrek naklinde kullanılan immünsüpresif tedaviler. İstanbul Bilim Üniversitesi Florence Nightingale Transplantasyon Dergisi. 2016 Feb. 1;1(1):48-52. doi:10.5606/fng.transplantasyon.2016.009