LABORATUVAR HAYVANLARINDA DENEYSEL EPİLEPSİ MODELLERİ

Year 2020, Volume: 3 Issue: 1, 38 - 51, 31.05.2020

Kayhan Özkan

Abstract

Epilepsi; merkezi sinir sisteminin bir kısmının veya tümünün anormal deşarjlar ile nöbetlere yol açan hastalığıdır. Dünya genelinde yaklaşık 70 milyon epilepsi hastası vardır. Hastalık ile mücadelede her geçen gün yeni ilaçlar geliştirilmektedir. Bu nedenle ilaçların insanlarda kullanılmadan önce deneysel hayvan modelleri kullanılarak analiz edilmesi gerekmektedir. Bu derlemede gelişim potansiyeli olan epilepsi ilaçlarının etkinliğinin araştırıldığı laboratuvar hayvanlarında deneysel epilepsi modelleri
incelenmiştir.

Keywords

Epilepsi modelleri, nöbet, ilaç, merkezi sinir sistemi, elektriksel deşarj

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