COMPARISON OF CANCER OR DYSPLASIA FREQUENCY BY AGE GROUPS IN PATIENTS WHO HAD CHOLECYSTECTOMY

Year 2022, Volume: 5 Issue: 3, 735 - 741, 26.12.2022

Arda Şakir Yılmaz , Necdet Fatih Yaşar , Setenay Öner , Deniz Arık

https://doi.org/10.52538/iduhes.1119702

Abstract

Safra kesesi karsinomları, safra yollarında görülen en sık görülen malignitedir. Spesifik belirti ve semptomları olmaması nedeniyle çoğu kez safra kesesi taşı nedeniyle yapılan kolesistektomi sırasında saptanmaktadır. Bu doğrultuda biz de çalışmamızda benign safra kesesi hastalıkları nedeniyle kolesistektomi yapılan olgularda displazi ve karsinom sıklığını göstermek amacıyla çalışmamıza dahil edilen 530 hastanın 74’ünde displazi, 3 hastada ise safra kesesi karsinomu saptanmıştır. Bu durum safra kesesi kanserlerinin erken evrede yakalanmasına ve tedavi başarısının oldukça yükseklere çıkarılmasında oldukça önemlidir. Bu nedenle benign nedenlerle bile olsa yapılan operasyon sonrası patoloji analiz raporlarını özenle takip etmek gerekmektedir.

Keywords

Kolesistektomi, displazi, safra kesesi karsinomu

COMPARISON OF CANCER OR DYSPLASIA FREQUENCY BY AGE GROUPS IN PATIENTS WHO HAD CHOLECYSTECTOMY

Abstract

Gallbladder carcinomas are the most common malignancy of the biliary tract. Since it does not have specific signs and symptoms, it is mostly detected during cholecystectomy for gallstones. In this direction, we also found dysplasia in 74 of the 530 patients included in our study, and gallbladder carcinoma in 3 patients, in order to show the frequency of dysplasia and carcinoma in patients who underwent cholecystectomy due to benign gallbladder diseases. This is very important in catching gallbladder cancers at an early stage and increasing the success of treatment. For this reason, it is necessary to carefully follow the pathology analysis reports after the operation, even for benign reasons.

Keywords

Cholecystectomy, dysplasia, gallbladder carcinoma

References

• 1.Lau CSM, Zywot A, Mahendraraj K, Chamberlain RS. Gallbladder Carcinoma in the United States: A Population Based Clinical Outcomes Study Involving 22,343 Patients from the Surveillance, Epidemiology, and End Result Database (1973-2013). HPB surgery: a world journal of hepatic, pancreatic and biliary surgery. 2017;2017:1532835-.
• 2.Lazcano‐Ponce EC, Miquel JF, Muñoz N, Herrero R, Ferrecio C, Wistuba II, et al. Epidemiology and molecular pathology of gallbladder cancer. CA: a cancer journal for clinicians. 2001;51(6):349-64.
• 3.Pandey M, Shukla VK. Diet and gallbladder cancer: a case–control study. European journal of cancer prevention. 2002;11(4):365-8.
• 4.Levy AD, Murakata LA, Rohrmann Jr CA. Gallbladder carcinoma: radiologic-pathologic correlation. Radiographics. 2001;21(2):295-314.
• 5.Dix FP, Bruce IA, Krypcyzk A, Ravi S. A selective approach to histopathology of the gallbladder is justifiable. The Surgeon. 2003;1(4):233-5.
• 6.Grobmyer SR, Lieberman MD, Daly JM. Gallbladder cancer in the twentieth century: single institution’s experience. World journal of surgery. 2004;28(1):47-9.
• 7.Kalita D, Pant L, Singh S, Jain G, Kudesia M, Gupta K, et al. Impact of routine histopathological examination of gall bladder specimens on early detection of malignancy-a study of 4,115 cholecystectomy specimens. Asian Pacific Journal of Cancer Prevention. 2013;14(5):3315-8.
• 8.Akyürek N, İrkörücü O, Salman B, Erdem Ö, Şare M, Tatlicioğlu E. Unexpected gallbladder cancer during laparoscopic cholecystectomy. Journal of Hepato-biliary-pancreatic surgery. 2004;11(5):357-61.
• 9.Hart J, Modan B, Shani M. Cholelithiasis in the aetiology of gallbladder neoplasms. The Lancet. 1971;297(7710):1151-3.
• 10.Serra I, Calvo A, Báez S, Yamamoto M, Endoh K, Aranda W. Risk factors of gallbladder cancer: An international collaborative case‐contol study. Cancer: Interdisciplinary International Journal of the American Cancer Society. 1996;78(7):1515-6.
• 11.Basak F, Hasbahceci M, Canbak T, Sisik A, Acar A, Yucel M, et al. Incidental findings during routine pathological evaluation of gallbladder specimens: review of 1,747 elective laparoscopic cholecystectomy cases. The Annals of The Royal College of Surgeons of England. 2016;98(4):280-3.
• 12.Siddiqui FG, Memon AA, Abro AH, Sasoli NA, Ahmad L. Routine histopathology of gallbladder after elective cholecystectomy for gallstones: waste of resources or a justified act? BMC surgery. 2013;13(1):1-5.
• 13.Sasatomi E, Tokunaga O, Miyazaki K. Precancerous conditions of gallbladder carcinoma: overview of histopathologic characteristics and molecular genetic findings. Journal of hepato-biliary-pancreatic surgery. 2000;7(6):556-67.
• 14.Yamagiwa H. Mucosal dysplasia of gallbladder: isolated and adjacent lesions to carcinoma. Japanese journal of cancer research. 1989;80(3):238-43.
• 15.Orth K, Beger HG. Gallbladder carcinoma and surgical treatment. Langenbeck's archives of surgery. 2000;385(8):501-8.
• 16.Roslyn JJ, Binns GS, Hughes EF, Saunders-Kirkwood K, Zinner MJ, Cates JA. Open cholecystectomy. A contemporary analysis of 42,474 patients. Annals of surgery. 1993;218(2):129.
• 17.Simopoulos C, Botaitis S, Polychronidis A, Tripsianis G, Karayiannakis AJ. Risk factors for conversion of laparoscopic cholecystectomy to open cholecystectomy. Surgical Endoscopy and Other Interventional Techniques. 2005;19(7):905-9.