Elektroeğirme Yöntemi ile Fibröz Doku İskelelerinin Üretimi

Year 2018, Volume: 1 Issue: 1, 31 - 34, 01.06.2018

Murat Şimşek

Abstract

Polimer çözeltilerinden veya eriyiklerinden
nano/mikro ölçekteki fiberlerin (lif) üretilmesine olanak sağlayan bir teknik olan
elektroeğirme tekniği Tıp’tan mühendisliğe kadar çok sayıda uygulamaya sahip birbiriyle
iç içe geçmiş nanofiber örgülerin elde edilmesinde sıklıkla kullanılmaktadır.  Nanofiber üretiminde kullanılan çekme, kalıp
(template) sentezi, faz ayrımı ve kendi kendine düzenlenme gibi yöntemlere nazaran,
sürekli fiber üretimine uygun, kullanımı kolay, çok yönlü ve düşük maliyetli bir
yöntemdir. Elektroeğirme tekniği ile üretilen nanofiberlerin olağanüstü yüzey alanı/hacim
oranına, kontrol edilebilir gözenek yapısına, yüksek gözenekliliğe, esnek yüzey
özelliklerine, yüksek işlevselliklere ve üstün mekanik özelliklere sahip olması
gibi birçok avantajı vardır. Bu teknik ile çeşitli formlarda (gelişigüzel ya da
doğrusal düzende) örülmemiş fiberlerin elde edilebilmesi mümkündür. Elektroeğirme
yöntemi ile fibröz formda iki ve üç boyutlu doku iskelelerinin üretilmesi sağladığı
avantajlar nedeni ile son dönemlerde oldukça ilgi çekici hale gelmiştir.

Keywords

nanofiber, doku iskelesi, doku mühendisliği, Elektroeğirme, doku mühendisliği

Fabrication of Two- and Three- Dimensional Fibrous Mats by Electrospinning Method

Abstract

Electrospinning technique, which
is a technique that allows the production of nano/micro nanofibers (fibers)
from polymer solutions or melts, is often used to obtain interconnected nanofiber
mats with many applications ranging from medicine to engineering. It is an easy
to use, versatile and cost-effective method suitable for continuous fiber
production compared to methods such as drawing, template synthesis, phase
separation and self-assembly. Nanofibers produced by electrospinning have many
advantages such as exceptional surface area / volume ratio, controllable pore
structure, high porosity, flexible surface properties, high functionality and
superior mechanical properties. With this technique it is possible to obtain nonwoven
fibers in various forms (random or aligned). Recently, it has become very
attractive due to the advantages of producing two- and three-dimensional tissue
scaffolds in fibrous form by electrospinning method.

Keywords

Electrospinning, nanofiber, fibrous mat, tissue scaffold, tissue engineering

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