Maliğn plevral sıvı, multipıl miyelomda (MM) oldukça nadir görülmektedir. Genellikle hastalığın geç dönemlerinde görülmekte ve kötü prognoza işaret etmektedir. MM nedeniyle 6 kür kemoterapi sonrası takipleri sırasında dispne gelişen 62 yaşındaki erkek hasta kiliniğimize gönderildi. Sağda massif plevral sıvı tespit edildi. Yapılan ponksiyonda alınan sıvıda, atipik plazma hücreleri görüldü. Dispneik olan hastada semptomatik rahatlama sağlamak için talk plöredez uygulandı. Miyelomatöz plevral sıvıların nadir görülmesi nedeniyle sunuldu.
1. Alexandrakis MG, Passam FH, Kyriakou DS,
Bouros D. Pleural effusion in hematologic
malignancies. Chest 2004; 125:1546-52.
2. Rodrigez JN, Pereira A, Martinez JC, et al.
Pleural effusion in multiple myeloma. Chest
1994;105: 622-4.
3. Rowe SM. Myelomatous pleural effusion and
airway compression complicating multiple
myeloma. Chest 2005; 128(4): 429-30.
4. Niscola P, Scaramucci L, Morabito F, et al.
Pleural effusion by malignant plasma cell in
advanced multiple myeloma: Report of three
cases with a brief overview. Haema 2004; 7 (4):
516-9.
5. Ulubay G. Eyübo¤lu FÖ, fiimflek A, et al.
Multiple myeloma with pleural involvement:
A case report. Am J Clin Oncol 2005; 28 (4):
429-30.
6. Kamble R, Wilson CS, Fassas A, et al. Malignant
pleural effusion of multiple myeloma:
Prognostic factors and outcome. Leuk Lymphoma
2005; 46 (8):1137-42 (abstract)
MYELOMATOUS PLEURAL EFFUSION: CASE REPORT
Year 2006,
Volume: 20 Issue: 1, 21 - 23, 01.05.2006
Malign pleural effusion in multiple myeloma (MM) is relatively infrequent. It is generally seen at later stages of the disease and related with poor prognose. 62 years old male patient referred to our clinic because of dyspnea after 6 cyclus of chemotherapy for MM. Massive pleural effusion was found on the right side. Atypical plasma cells seen in effusion after thoracentesis. Talc pleurodesis performed for symptomatic relief of the patient who was dyspneic. We reported the case because myelomatous pleural effusions seen relatively rare.
1. Alexandrakis MG, Passam FH, Kyriakou DS,
Bouros D. Pleural effusion in hematologic
malignancies. Chest 2004; 125:1546-52.
2. Rodrigez JN, Pereira A, Martinez JC, et al.
Pleural effusion in multiple myeloma. Chest
1994;105: 622-4.
3. Rowe SM. Myelomatous pleural effusion and
airway compression complicating multiple
myeloma. Chest 2005; 128(4): 429-30.
4. Niscola P, Scaramucci L, Morabito F, et al.
Pleural effusion by malignant plasma cell in
advanced multiple myeloma: Report of three
cases with a brief overview. Haema 2004; 7 (4):
516-9.
5. Ulubay G. Eyübo¤lu FÖ, fiimflek A, et al.
Multiple myeloma with pleural involvement:
A case report. Am J Clin Oncol 2005; 28 (4):
429-30.
6. Kamble R, Wilson CS, Fassas A, et al. Malignant
pleural effusion of multiple myeloma:
Prognostic factors and outcome. Leuk Lymphoma
2005; 46 (8):1137-42 (abstract)