Abstract
Hamartom en sık izlenen benign akciğer tümörüdür. Bu çalışmada, kliniğimizde son sekiz yıl içinde akciğer hamartomu nedeniyle cerrahi tedavi uyguladığımız 15 olgunun klinik özelliklerini retrospektif olarak inceledik. Dokuzu erkek, altısı kadın olup olguların yaş ortalaması 49.1±12.5 (30-74) idi. Olguların yaş ve cinsiyeti, hamartomun lokalizasyon ve boyutu, kalsifikasyon varlığı ve uygulanan operatif işlemler incelendi. Onbeş hastanın 10u (%66.7) asemptomatik iken, beşinde öksürük yakınması bulunmaktaydı. Ha-martomlar sol akciğerde daha fazla (%60) izlenmekte olup ortalama çap 2.3±1.2 (1-6) cm idi. Serimizde rezeksiyon sonrası hamartom nüksü veya primer akciğer karsinomu gelişimi izlenmemiştir. Ortalama izlem süresi 55.2±36.0 (9-112) aydı. Akciğer h amartomlarının büyük çoğunluğu soliter nodül olarak izlenmektedir. Kesin tanı ve tedavi akciğer tümörünün rezeksiyonuyla sağlanabilmektedir.
References
- 1. Yüksel M, Akgül A. Akci¤erin iyi huy lu tümörleri. Yüksel M, Kalayc› G (ed). Gö¤üs cerrahisi. ‹stanbul: Bilmedya Grup; 2001: 221-4.
- 2. Shields TW, Robinson PG. Benign tumors of the lung. In: Shields TW, LoCicero J, Ponn RB, Rusch VW (eds). General thoracic surgery. Philadelphia: Lippincott Williams & Wilkins; 2005: 1778-85.
- 3. Shinkai M, Kobayashi H, Kanoh S, Ozeki Y, Aida S, Motoyoshi K. Pulmonary hamartoma: unusual radiological appearance. J Thorac Imaging 2004; 19: 38-40.
- 4. Lien YC, Hsu HS, Li WY, Wu YC, Hsu WH, Wang LS, Huang MH, Huang BS. Pulmonary hamartoma. J Chin Med Assoc 2004; 67: 21-6.
- 5. Lee SY, Park HJ, Lee CS, Lee KR. Giant pulmonary hamartoma. Eur J Cardiothorac Surg 2002; 22: 1006.
- 6. Cosio BG, Villena V, Echave-Sustaeta J, Miguel E, Alfaro J, Hernandez L, Sotelo T. Endobronchial hamartoma. Chest 2002; 122: 202-5.
- 7. Kim GY, Han J, Kim DH, Kim J, Lee KS. Giant cystic chondroid hamartoma. J Korean Med Sci 2005; 20: 509-11.
- 8. Y›lmaz S, Ekici A, Erdo¤an S, Ekici M. Endobronchial lipomatous hamartoma: CT and MR imaging features. Eur Radiol 2004; 14: 1521-4.
- 9. Ganti S, Milton R, Davidson L, Anikin V. Giant pulmonary hamartoma. J Cardiothorac Surg 2006; 1: 19.
- 10. Kaptano¤lu M, Nadir A, Y›ld›z E, Elagöz S. Pulmonary hamartoma: a rare presentation. Eur J Cardiothorac Surg 2001; 20: 1031.
- 11. Pelosi G, Rosai J, Viale G. Immunoreactivity for sex steroid hormone receptors in pulmonary hamartomas. Am J Surg Pathol 2006; 30: 819-27.
- 12. Hansen CP, Holtveg H, Francis D, Rasch L, Bertelsen S. Pulmonary hamartoma. J Thorac Cardiovasc Surg 1992; 104: 674-8.
- 13. Tomiyasu M, Yoshino I, Suemitsu R, Shoji F, Sugimachi K. An intrapulmonary chondromatous hamartoma penetrating the visceral pleura: report of a case. Ann Thorac Cardiovasc Surg 2002; 8: 42-4.
- 14. Ribet M, Jaillard-Thery S, Nuttens MC. Pulmonary hamartoma and malignancy. Thorac Cardiovasc Surg 1994; 107: 611-4.
Abstract
Pulmonary hamartoma is the most common type of benign lung tumors. In this study, we retrospectively reviewed the clinical features of 15 patients with pulmonary hamartomas undergoing surgical resection in our clinic, during a period of last eight years. Nine were male and six were female. Their mean age 49.1±12.5 (30-74) years. The data regarding age, gender, symptoms, location of hamartoma, size of lesions, state of calcification in the hamartoma, operative procedures are analyzed. Of the 15 patients with pulmonary hamartoma, 10 patients (66.7%) were clinically asemptomatic, five patients had cough. The hamartomas were seen dominant in the left lung (60%) with the mean diameter of 2.3±1.2 (1-6) cm measured. No hamartoma recurrence and primary lung carcinoma appearance developed after resection in our series. The mean follow-up was 55.2±36.0 (9-112) months. The most of pulmonary hamartomas represent as solitary pulmonary nodule. The definitive diagnosis and treatment can be achieved by surgical resection of pulmonary tumor.
References
- 1. Yüksel M, Akgül A. Akci¤erin iyi huy lu tümörleri. Yüksel M, Kalayc› G (ed). Gö¤üs cerrahisi. ‹stanbul: Bilmedya Grup; 2001: 221-4.
- 2. Shields TW, Robinson PG. Benign tumors of the lung. In: Shields TW, LoCicero J, Ponn RB, Rusch VW (eds). General thoracic surgery. Philadelphia: Lippincott Williams & Wilkins; 2005: 1778-85.
- 3. Shinkai M, Kobayashi H, Kanoh S, Ozeki Y, Aida S, Motoyoshi K. Pulmonary hamartoma: unusual radiological appearance. J Thorac Imaging 2004; 19: 38-40.
- 4. Lien YC, Hsu HS, Li WY, Wu YC, Hsu WH, Wang LS, Huang MH, Huang BS. Pulmonary hamartoma. J Chin Med Assoc 2004; 67: 21-6.
- 5. Lee SY, Park HJ, Lee CS, Lee KR. Giant pulmonary hamartoma. Eur J Cardiothorac Surg 2002; 22: 1006.
- 6. Cosio BG, Villena V, Echave-Sustaeta J, Miguel E, Alfaro J, Hernandez L, Sotelo T. Endobronchial hamartoma. Chest 2002; 122: 202-5.
- 7. Kim GY, Han J, Kim DH, Kim J, Lee KS. Giant cystic chondroid hamartoma. J Korean Med Sci 2005; 20: 509-11.
- 8. Y›lmaz S, Ekici A, Erdo¤an S, Ekici M. Endobronchial lipomatous hamartoma: CT and MR imaging features. Eur Radiol 2004; 14: 1521-4.
- 9. Ganti S, Milton R, Davidson L, Anikin V. Giant pulmonary hamartoma. J Cardiothorac Surg 2006; 1: 19.
- 10. Kaptano¤lu M, Nadir A, Y›ld›z E, Elagöz S. Pulmonary hamartoma: a rare presentation. Eur J Cardiothorac Surg 2001; 20: 1031.
- 11. Pelosi G, Rosai J, Viale G. Immunoreactivity for sex steroid hormone receptors in pulmonary hamartomas. Am J Surg Pathol 2006; 30: 819-27.
- 12. Hansen CP, Holtveg H, Francis D, Rasch L, Bertelsen S. Pulmonary hamartoma. J Thorac Cardiovasc Surg 1992; 104: 674-8.
- 13. Tomiyasu M, Yoshino I, Suemitsu R, Shoji F, Sugimachi K. An intrapulmonary chondromatous hamartoma penetrating the visceral pleura: report of a case. Ann Thorac Cardiovasc Surg 2002; 8: 42-4.
- 14. Ribet M, Jaillard-Thery S, Nuttens MC. Pulmonary hamartoma and malignancy. Thorac Cardiovasc Surg 1994; 107: 611-4.
Details
| Other ID | JA34MM72DJ |
|---|---|
| Journal Section | Research Article |
| Authors | |
| Publication Date | May 1, 2007 |
| Published in Issue | Year 2007 Volume: 21 Issue: 1 |