ORAL KAVİTE TÜBERKÜLOZU: BİR OLGU SUNUMU

Year 2010, Volume: 24 Issue: 3, 197 - 202, 01.12.2010

Ahmet Bircan İlkay Yılmazer Özkan Kılıç Faika Büyükvanlı

Abstract

Kutanöz tüberkülozun oldukça nadir bir formu olan orifisiyal tüberküloz, kutanöz tüberküloz olguları arasında % 2, tüberküloza ait tüm klinik formlar arasında ise %0.1 ile %1 oranında görülür. Primer oral tüberküloz lezyonları bölgesel lenfadenopati ile birlikte ağrısız ülserler şeklinde ve gençlerde meydana gelirken, sekonder formlar her yaşta görülebilir ve genellikle de akciğer tüberkülozu ile birliktedir. Burada 3 yıldır alt dudağındaki iyileşmeyen ülsere lezyona tanı konamamış 29 yaşındaki erkek hastadaki miliyer yayılım gösteren akciğer tüberkülozu ve sekonder oral kavite tüberkülozu güncel literatür eşliğinde sunulmuştur. Sonuç olarak, iyileşmeyen oral lezyonların ayırıcı tanısında oral kavite tüberkülozu akılda tutulmalı ve altta yatan bir akciğer tüberkülozunun varlığı araştırılmalıdır.

Keywords

Tüberküloz, dudak, oral kavite

ORAL CAVITY TUBERCULOSIS: A CASE REPORT

Abstract

Orificial tu berculosis, a rare form of cutaneous tuberculosis, represents 2% of cutaneous tuberculosis and 0.1-1% of all clinical forms of tuberculosis. The primary form of oral tuberculosis presents as painless ulcer with regional lymphadenopathy at young patients whereas the secondary form occurs at every age and frequently presents with pulmonary tuberculosis. Here, a secondary form of oral cavity tuberculosis in association with miliary spread from pulmonary tuberculosis a 29 years old man had a non-healing ulcer on his lower lip which was not diagnosed for three years is presented in the view of literature. As a conclusion, oral cavity tuberculosis should be kept in mind in the differential diagnosis of non-healing oral lesions and the presence of pulmonary tuberculosis should be screened in such cases.

Keywords

Tuberculosis, lip, oral cavity

References

• 1. Ichihashi K, Katoh N, Takenaka H, Kishimoto S. Orificial tuberculosis presenting as a refractory perianal ulcer. Acta Derm Venereol 2004; 84: 331-2.
• 2. Zouhair K, Akhdari N, Nejjam F, Ouazzani T, Lakhdar H. Cutaneous tuberculosis in Morocco. Int J Infect Dis 2007; 11: 209-12.
• 3. Chen YJ, Shieh PP, Shen JL. Orificial tuberculosis and Kaposi’s sarcoma in an HIV-negative individual. Clin Exp Dermatol 2000; 25: 393-7.
• 4. Ilyas SE, Chen FF, Hodgson TA, Speight PM, Lacey CJ, Porter SR. Labial tuberculosis: a unique cause of lip swelling complicating HIV infection. HIV Med 2002; 3: 283-6.
• 5. Eng HL, Lu SY, Yang CH. Oral tuberculosis. Oral Surg Oral Med Oral Pathol 1996; 81: 415-20.
• 6. Köksal D, Ac›can T, Kanat F, Durmaz G. Tuberculous ulcer of the tongue secondary to pulmonary tuberculosis. Aust NZJ Med 2000; 30: 518-9.
• 7. Jaward J, EL Znebi F. Primary lingual tuberculosis: A case report. J Laryngol Otol 1996; 110: 1778-80.
• 8. Murray A, Gardiner DS, McGuiness RJ. Primary mycobacterial infection of the uvula. J Laryngol Otol 1998; 112: 1183-5.
• 9. Perrotti V, Petrone G, Rubini C, Fioroni M, Piattelli A. Tuberculosis cutis of buccal mucosa. J Otolaryngol 2005; 34: 274-6.
• 10. Tüzün Y, Marafll›o¤lu T. Orifisyel tüberküloz. Dermatose; 2006; 5: 209-12.
• 11. Jadassohn J. Tuberculosis ulcerosa miliaris (tuberculosis propria cutis et mucosae). In: Mracek F, ed. Handbuch der Hautkrankheiten. Vol- IV. Vienna: Alfred Hölder Buchverlag, 1907. p.239-47.
• 12. Wolff K. Mycobacterial diseases. In: Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen FK, eds. Dermatology in general medicine. New York: McGraw-Hill, 1979. p.1473-92.
• 13. Prada JL, Kindelan JM, Villanueva JL, Jurado R, Sánchez-Guijo P, Torre-Cisneros J. Tuberculosis of the tongue in two immunocompetent patients (letter). Clin Infect Dis 1994; 19: 200-2.
• 14. Turbiner S, Giunta J, Maloney PL. Orificial tuberculosis of the lip. J Oral Surg 1975; 33: 443-7.
• 15. Yigit O, Cinar U, Uslu Coflkun B, Baflak T. Tuberculous ulcer of the tongue: a case report. Kulak Burun Bogaz Ihtis Derg 2004; 13: 98–101.
• 16. Gamble EA, Davison AG. Chronic lip ulceration in association with an abnormal chest radiograph. Respiration 1999; 66: 477-8.
• 17. Dixit R, Sharma S, Nuwal P. Tuberculos›s of oral cavity. Indian J Tuberc 2008; 55: 51-3.
• 18. Erbaycu AE, Taymaz Z, Tuksavul F, Afrashi A, Güçlü SZ. What happens when oral tuberculosis is not treated? Monaldi Arch Chest Dis 2007; 67: 116-8.
• 19. Kiliç A, Gül U, Gönül M, Soylu S, Cakmak SK, Demiriz M. Orificial tuberculosis of the lip: a case report and review of the literature. Int J Dermatol 2009; 48: 178-80.
• 20. Nachbar F, Classen V, Nachbar T, Meurer M, Schirren CG, Degitz K. Orificial tuberculosis: detection by polymerase chain reaction. Br J Dermatol 1996; 135: 106-9.