KOAH'DA NİTRİK OKSİT VE TOTAL ANTİOKSİDAN KAPASİTE DÜZEYLERİNİN ÖLÇÜMÜ

Year 2011, Volume: 25 Issue: 1, 21 - 25, 01.05.2011

Osman Evliyaoglu Halide Kaya Abdullah Çetin Tanrıkulu Abdurrahman Abakay Özlem Abakay Cengizhan Sezgi Yılmaz Palancı

Abstract

Bu çalışmada stabil KOA H hastalarında serumda nitrik oksit (NO) ve total antioksidan kapasite (TAOK) düzeyleri çalışılmıştır. KOAH'lı 47 hasta ile aynı sayıdaki sağlıklı erişkin kontrol grubu olarak çalışmaya alındı. Hasta ve kontrol grubu serumlarında oksidatif stres belirteci olarak nitrik oksit (NO) düzeyleri ile antioksidan savunma sisteminin toplam göstergesi olan total antioksidan kapasite (TAOK) ölçüldü. KOAH hasta grubu 47 kişiydi (27 erkek, 20 kadın) ve yaş ortalaması 66.7±8.3 yıldı. Kontrol grubu da 47 kişiydi (28 erkek, 19 kadın) ve yaş ortalaması 63.2±9.4 yıldı ve iki grup yaş ve cinsiyet açısından arasında fark saptanmadı.

Keywords

KOAH, oksidatif stres, antioksidan savunma sistemi

MEASURING THE LEVELS OF NITRIC OXIDE AND TOTAL ANTIOXIDANT CAPACITY IN COPD

Abstract

In this study were studied level of serum nitric oxide (NO) and total antioxidant capacity (TAS) levels in stable COPD patients. A total of 47 patients with stable COPD and 47 control were included the study. In patients and control group, as a marker of oxidative stress in serum of nitric oxide (NO) levels and total anti-oxidant defense system, which is an indicator of total antioxidant capacity (TAS) were measured. 47 was the group of COPD patients (27 men, 20 women) and mean age 66.7±8.3 years. The control group also was the 47 (28 male, 19 female) and mean age 63.2±9.4 years, and there was no difference between the two groups in terms of age and gender.

Keywords

COPD, oxidative stress, antioxidant defense system

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