KOAH'LI HASTALARDA GASTROOZAFAGİAL REFLÜ HASTALIĞI SIKLIĞININ SİNTİGRAFİ İLE DEĞERLENDİRİLMESİ

Year 2011, Volume: 25 Issue: 1, 27 - 33, 01.05.2011

Ercan Çil İşıl Karasu Ayşe Özsöz Engin Özbilek Hakan Koparal Ahmet Emin Erbaycu

Abstract

Gastroözafagial reflü (GÖR) hastalığı kronik obstrüktif akciğer hastalığı (KOAH) kliniğini ve semptomatolojiyi etkileyen bir eş zamanlı hastalıktır. Bu çalışmada KOAH'lı hastalarda GÖR hastalığı sıklığını GÖR sintigrafisi ile araştırmak ve solunum fonksiyonları ile ilişkisini ortaya koymak amaçlanmıştır. Çalışma grubuna KOAH, akut alevlenme ve solunum yetmezliği bulunan hastalar, kontrol grubuna kronik solunumsal hastalığı olmayan, GÖR ile uyumlu semptomları olan hastalar alındı. Hastaların semptomları, spirometri ve gastroözafagial reflü sintigrafisi sonuçları kaydedildi. Çalışma grubuna 85, kontrol grubuna 27 hasta alındı. Gastroözafagial reflü ile ilişkili semptomu olan KOAH'lı hastalarda FEV1 değerleri (%28.6) daha düşük idi. Sintigrafi KOAH grubunda %4.7 hastada pozitif iken, kontrol grubunda pozitiflik saptanmadı. KOAH akut alevlenmesi ve solu num yetmezliğinde GÖR sintigrafisi ile ortaya konulan GÖR prevalansı GÖR semptomları olan hastalara göre daha fazla değildir. Gastroözafagial reflü, akut alevlenme ve solunum yetmezliği tablosundaki KOAH'lı hastalarda bir risk faktörü olarak bulunmamıştır.

Keywords

Kronik obstrüktif akciğer hastalığı, Gastroözafagial reflü hastalığı, OZET Gastroözafagial reflü sintigrafisi

THE EVALUATION OF THE FREQUENCY OF GASTROESOPHAGEAL REFLUX DISEASE BY SCINTIGRAPHY IN PATIENTS WITH COPD

Abstract

Gastroesophageal reflux (GER) disease is a concomitant disease that affect the clinical situation and symptomatology in chronic obstructive pulmonary disease (COPD). In this study it was aimed to reveal the frequency of GER disease using GER scintigraphy and mark the relation with respiratory functions. In COPD group, there were patients with COPD, acute exacerbation and respiratory failure, where control group contained patients having symptoms related GER without any chronic respiratory diseases. Symptoms, results of spirometry and GER scintigraphy were assessed. There were 85 patients in COPD group and 27 in control group. FEV1 was lower (28.6%) in COPD patients those with symptoms related with GER. Scintigraphy was positive in 4.7% of COPD patients while there was no positive result in control group. The prevalance of GER diagnosed with GER scintigraphy is not higher in COPD plus acute exacerbation and respiratory failure than those having GER symptoms. Gastroesophageal reflux is not a risk factor in patients with COPD with acute exacerbation and respiratory failure.

Keywords

Chronic obstructive pulmonary disease, Gastroesophageal reflux disease, Gastroesophageal reflux scintigraphy

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