KİTLE ŞEKLİNDE PREZENTE OLAN AMIODARONA BAĞLI BİR ORGANİZE PNÖMONİ OLGUSU

Year 2011, Volume: 25 Issue: 3, 177 - 181, 01.12.2011

Melih Büyükşirin Ceyda Anar Günhan Yavaşoğlu Hüseyin Halilçolar Nur Yücel

Abstract

Amiodaron pulmoner fibrozise gidebilecek intertisyel pnömoniye neden olan antiaritmik bir ilaçtır. Altmış dört yaşında dispne, ateş, öksürük yakınması ile başvuran erkek hastanın özgeçmişinden amiodaron, metoprolol ve aspirin ilaçlarını kullandığı öğrenildi. Yüksek rezolüsyonlu bilgisayarlı tomografisinde (YRBT) bilateral üst loblarda lokalize konsolidasyon görünümlü lezyonların olması ve tru-cut doku biyopsisinin organize pnömoni olarak yorumlanması sonucunda hastada amiodarona bağlı pulmoner toksisite düşünüldü. Steroid tedavisi başlandıktan üç ay sonra çekilen göğüs radyogramında tam regresyon izlendi. Bu olguda YRBT'de amiodaron toksisitesinin en sık görülen bulgusu olan bilateral intertisyel infiltratlar yerine daha nadir görülen iyi lokalize edilen kitle ve konsolidasyon görünümlerin de olabileceği vurgulanmıştır. Ayrıca solunum sistemi yakınmaları ile gelen hastalarda öykü alırken kullanmakta olduğu ilaçları detaylı bir şekilde sorgulamakta yarar olduğunu düşünmekteyiz.

Keywords

Amiodaron, organize pnömoni, akciğer, konsolidasyon, kitle, toksisite

A CASE OF AMIODARONE INDUCED ORGANIZING PNEUMONIA PRESENTING AS A PULMONARY MASS

Abstract

Amiodarone is an antiarrhythmic drug that can cause interstitial pneumonitis leading to pulmonary fibrosis. Amiodarone, metoprolol, and aspirin drugs had been used by a 64 year old man who admitted with dyspnea, fever, cough. Bilateral localized consolidation lesion was in upper lobes in high resolution computed tomography ( HRCT) and tru- cut tissue biyopsy was reported as organizing pneumonia; so amiodarone-induced pulmonary toxicity was thought in the patient. Three months after cessation of steroid treatment, chest radyogram shows complete regression of pneumonitis. The present case report demonstrates the localized mass, and consolidation lesions that is seen very rare instead of bilateral interstitial infiltrates that is the most common HRCT findings of amiodarone toxicity. In addition, we thougt that drugs that has been used must cross-examine in detail in the patients admitted with respiratory symptoms.

Keywords

Amiodaron, organizing pneumonia, pulmonary, consolidation, mass, toxicity

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