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AKCİĞERİN PRİMER “LENFOEPİTELYOMA-BENZERİ KARSİNOMA” OLGUSU

Year 2013, Volume: 27 Issue: 3, 215 - 218, 01.12.2013

Abstract

Lenfoepitelyoma-benzeri karsinoma (LEBK) genellikle nasofaringeal bölgenin primer tümörüdür. Akciğerin primer LEBK'sı nadirdir. Akciğer grafisinde soliter pulmoner nodül saptanan 41 yaşındaki bayan olguda yapılan incelemeler sonucu primer akciğer malignitesi ön tanısı ile küratif cerrahi rezeksiyon uygulandı. Lezyonun histopatolojik tanısı LELBK olarak rapor edildi. EBV-EA ve EBV VCA IgG pozitif idi. Primer akciğer LEBK nedeni ile sol üst lobektomi uyguladığımız olgu literatür bilgileri eşliğinde sunulmuştur.

References

  • 1. Begin LR, Eskandari J, Joncas J, Panasci L. Ebstein-Barr virus related lymphoepitheliomalike carcinoma of lung. J Surg Oncol 1987: 36: 280-3.
  • 2. Mary BB, Elisabeth B, William DT. The 2004 World Health Organization Classification of Lung tumors. Seminars in Roentgenology.
  • 3. Chen FF, Yan JJ, Lai WW, Jin YT, Su IJ. EpsteinBarr virus-associated nonsmall cell lung carcinoma: undifferentiated "lymphoepitheliomalike" carcinoma as a distinct entity with better prognosis. Cancer 1998; 82(12): 2334-42.
  • 4. Han AJ, Xiong M, Gu YY, Lin SX, Xiong M Lymphoepithelioma-like carcinoma of the lung with a better prognosis. A clinicopathologic study of 32 cases. Am J Clin Pathol. 2001; 115(6): 841-50.
  • 5. Bildirici K, Ak G, Peker B, Metintaş M, Alataş F, Erginel S, Uçgun İ. Akciğerin primer lenfoepitelyoma benzeri karsinomu. Tuberkuloz ve Toraks Dergisi 2005; 53: 69-73.
  • 6. Gomez-Roman JJ, Martinez MN, Fernandez SL, Val-BernalJF. Epstein–Barr virus-associated adenocarcinomas and squamous-cell lung carcinomas Modern Pathology 2009; 22: 530-7.
  • 7. Ooi GC, Ho JCM, Khong PL, WongMP, Lam WK, Tsang KWT. Computed tomography characteristics of advanced primary pulmonary lymphoepithelioma-like carcinoma. Eur Radiol 2003; 13: 522-6.
  • 8. Chan AT, Teo PM, Lam KC, Chan WY, Chow JH, Yim AP, et al. Multimodality treatment of primary lymphoepithelioma-like carcinoma of the lung. Cancer 1998; 83: 925-9.
  • 9. Gözübüyük A, Kavaklı K, Çaylak H, Genç O. Akciğer yerleşimli lenfoepitelyoma benzeri karsinomlu bir olgu. Tur Toraks Der 2009;10:201-3.
  • 10.Yazıcı Ü, Gülhan E, Aydın E, Yaran P, Taştepe İ. Akciğerde primer “Lenfoepitelyoma-like” Karsinoma. J. Clin. Ana. Med 2010; 1(2): 40-3.

PRIMARY LYMPHOEPITHELIOMA-LIKE CARCINOMA OF THE LUNG

Year 2013, Volume: 27 Issue: 3, 215 - 218, 01.12.2013

Abstract

Lymphoepithelioma-like carcinoma (LELC), best known to occur in the nasopharynx. Primary LELC of the lung is very rare. Curative surgical resection was performed in a 41-year-old woman with prediagnosis of primary lung malignancy who had been referred with solitary pulmonary nodule. The histopathological diagnosis was lymphoepithelioma-like carcinoma of the lung. Immunohistochemical analysis was positive for Epstein-Barr virus (EBV-EA and EBV VCA IgG was positive). We presented the case with the literature data who had gone left upper lobectomy for primary lung LELC.

References

  • 1. Begin LR, Eskandari J, Joncas J, Panasci L. Ebstein-Barr virus related lymphoepitheliomalike carcinoma of lung. J Surg Oncol 1987: 36: 280-3.
  • 2. Mary BB, Elisabeth B, William DT. The 2004 World Health Organization Classification of Lung tumors. Seminars in Roentgenology.
  • 3. Chen FF, Yan JJ, Lai WW, Jin YT, Su IJ. EpsteinBarr virus-associated nonsmall cell lung carcinoma: undifferentiated "lymphoepitheliomalike" carcinoma as a distinct entity with better prognosis. Cancer 1998; 82(12): 2334-42.
  • 4. Han AJ, Xiong M, Gu YY, Lin SX, Xiong M Lymphoepithelioma-like carcinoma of the lung with a better prognosis. A clinicopathologic study of 32 cases. Am J Clin Pathol. 2001; 115(6): 841-50.
  • 5. Bildirici K, Ak G, Peker B, Metintaş M, Alataş F, Erginel S, Uçgun İ. Akciğerin primer lenfoepitelyoma benzeri karsinomu. Tuberkuloz ve Toraks Dergisi 2005; 53: 69-73.
  • 6. Gomez-Roman JJ, Martinez MN, Fernandez SL, Val-BernalJF. Epstein–Barr virus-associated adenocarcinomas and squamous-cell lung carcinomas Modern Pathology 2009; 22: 530-7.
  • 7. Ooi GC, Ho JCM, Khong PL, WongMP, Lam WK, Tsang KWT. Computed tomography characteristics of advanced primary pulmonary lymphoepithelioma-like carcinoma. Eur Radiol 2003; 13: 522-6.
  • 8. Chan AT, Teo PM, Lam KC, Chan WY, Chow JH, Yim AP, et al. Multimodality treatment of primary lymphoepithelioma-like carcinoma of the lung. Cancer 1998; 83: 925-9.
  • 9. Gözübüyük A, Kavaklı K, Çaylak H, Genç O. Akciğer yerleşimli lenfoepitelyoma benzeri karsinomlu bir olgu. Tur Toraks Der 2009;10:201-3.
  • 10.Yazıcı Ü, Gülhan E, Aydın E, Yaran P, Taştepe İ. Akciğerde primer “Lenfoepitelyoma-like” Karsinoma. J. Clin. Ana. Med 2010; 1(2): 40-3.
There are 10 citations in total.

Details

Other ID JA33ZV34VP
Journal Section Case Report
Authors

Serpil Sevinç This is me

Onur Akçay This is me

Şaban Ünsal This is me

Şeyda Örs Kaya This is me

Nur Yücel This is me

Publication Date December 1, 2013
Published in Issue Year 2013 Volume: 27 Issue: 3

Cite

APA Sevinç, S., Akçay, O., Ünsal, Ş., Kaya, Ş. Ö., et al. (2013). AKCİĞERİN PRİMER “LENFOEPİTELYOMA-BENZERİ KARSİNOMA” OLGUSU. İzmir Göğüs Hastanesi Dergisi, 27(3), 215-218.