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BRONŞEKTAZİNİN CERRAHİ TEDAVİSİ: 45 HASTANIN ERKEN VE GEÇ DÖNEM SONUÇLARI

Year 2014, Volume: 28 Issue: 1, 31 - 37, 01.05.2014

Abstract

Bronşektazi genellikle pulmoner enfeksiyonlar ve bronşial obstrüksiyona sekonder olarak gelişir. Halen ülkemiz gibi gelişmekte olan ülkelerde ciddi bir sağlık problemidir. Retrospektif yaptığımız çalışmamızın amacı bronşektazinin cerrahi tedavisindeki deneyimlerimiz ile erken ve geç dönem takip sonuçlarımızı sizlere sunmaktır. Kliniğimizde Ocak 2003 ile Mart 2011 arasında bronşektazi nedeni ile opere ettiğimiz 45 hastanın dosyaları retrospektif olarak incelendi. Olguların demografik özellikleri, semptomlar, etyoloji, rezeksiyon tipi, mortalite, morbidite ve takip sonuçları kayıt edildi ve değerlendirildi. Olguların 23(%55,1)ü bayan, 22(%48,9)si erkekti ve ortalama yaş 30,3 idi(6-63 yaş aralığı). Semptomlar 35 olguda aşırı miktarda pürülan balgam, 30 olguda kötü kokulu balgam ekspektorasyonu, 20 olguda dispne ve tüm olgularda öksürük idi. Toplamda 34 lobektomi, üç lobektomi+ segmentektomi, altı segmentektomi, bir bilobektomi ve beş wedge rezeksiyon uygulandı. Postoperatif erken komplikasyon 17 olgumuzda görüldü. Serimizde mortalitemiz olmadı. Takiplerimiz 39 olguda 24 aya tamamlandı. Altı olgu takip edilemedi. Semptomlar 28 olguda tamamen kayboldu, yedi olguda azalırken, dört olgumuzda ise düzelme olmadı yada daha kötüye gitti. Bronşektazi tedavisinde öncelik medikal tedavidir. Medikal tedavinin yetersiz kaldığı özellikle lokalize hastalıkta ise cerrahi iyi bir seçenektir. Bronşektazide cerrahi rezeksiyonlar kabul edilebilir mortalite ve morbidite ile uygulanabilmektedir. Bilateral diffüz hastalıkta ise akciğer transplantasyonu güncel ve umut verici bir tedavi seçeneğidir.

References

  • 1. Kavukçu Ş. Akciğerin süpüratif hastalıkları, In: Ökten İ, ed. Göğüs Cerrahisi, 1 Baskı, cilt 2, Ankara: Sim Matbaacılık,2003;1001-9.
  • 2. Yıldızeli B, Yüksel M. Pnömoni, akciğer apsesi ve bronşektazi. In: Yüksel M, Kalaycı G; eds. Göğüs Cerrahisi.1.Baskı İstanbul: Özlem Grafik Matbaacılık,2001;659-76.
  • 3. Miller JI. Bronchiectasis. In: Shields TW, LoCicero J, Reed CE, Feins RH, editors. General Thoracic Surgery. 7 th ed. Philedelphia: Lippincotts, Williams and Wilkins; 2000. p. 1117-9.
  • 4. Baklanli K, Genç O, Dakak M, et al. Surgical management of bronchiectasis: analysing and short-term results in 238 patient. Eur J Cardiothorac Surg. 2003; 24(5): 699-702.
  • 5. Kutlay H, Cangir AK, Enön S, et al. Surgica treatment in bronchiectasis: analysis of 166 patients. Eur J Cardiothorac Surg. 2002; 21(4): 634-7.
  • 6. Özdemir Ö. Bronşektazi. Solunum Sistemi ve Hastalıkları. Numanoğlu N ed. Ankara: Antıp AŞ, 1997:421-31.
  • 7. Doğan R, Alp M, Kaya S, et al. Surgical treatment of bronchiectasis: a collective review of 487 cases. Thorac Cardiovasc Surg. 1989; 37(3): 183-6.
  • 8. Nikolaizik WH, Warner JO. Etiology of chronic suppurative lung disease. Arch Dis Child 1994; 70: 141-2.
  • 9. Karasu S. Bronşektazide cerrahi tedavinin yeri. Uzmanlık Tezi. Ankara: Atatürk Göğüs Hastalıkları Ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi,2003.
  • 10. Bruggen-Bogaarts B, Bruggen H, Waes P, et al. Screening for bronchiectasis. A comparative study between chest radiography and highresolution CT. Chest 1996; 109: 608-11
  • 11. Ooi GC, Khong PL, Chan-Yeung M, et al. Highresolution CT quantification of bronchiectasis: Clinical and functional correlation. Radiology 2002; 225(3): 663-72.
  • 12. Kang EY, Miller RR, Muller NL. Bronchiectasis: Comprasion of preoperative thin-section CT and pathologic findins in resected specimens. Radiology 1995; 195: 649-54
  • 13. Prieto D, Bernardo J, Matos MJ, et al. Sugery for bronchiectasis. Eur J Cardiothorac Surg 2001; 20: 19-23
  • 14. Laros CD, Van Den Bosch CM, Westermann CJ, et al. Resection of more than 10 lung segments: A 30-year survey of bronchiectatic patients. J Thorac Cardiovasc Surg. 1988; 95(1): 119-23.
  • 15. Hayes D Jr, Meyer KC. Lung transplantation for advanced bronchiectasis. Semin Respir Crit Care Med. 2010; 31(2): 123-38
  • 16. Beirne PA, Banner NR, Khaghani A, et al. Lung transplantation for non-cystic fibrosis bronchiectasis: analysing of a 13 –year experience. J Heart Lung Transplant. 2005; 24(10): 1530-35.
  • 17. Nathan JA, Sharples LD, Exley AR, et al. The outcomes of lung transplantation in patients with bronchiectasis and antibody deficiency. J Heart Lung Transplant. 2005; 24(10): 1517-21.
  • 18. Groen H, Van der Bij W, Koeter GH, Tenvergert EM. Cost-effectiveness of lung transplantation in relation to type of end-stage pulmonary disease. Am J Transplant. 2004; 4(7): 1155-62.
  • 19. Zhang P, Zhang F, Jiang S, et al. Video-assisted thoracic surery for bronchiectasis. Ann Thorac Surg. 2011; 91(1): 239-43.
  • 20. Yang F, Li Y, Liu J, et al. Video-assisted thoracoscopic lobectomy for benign pulmonary disease. Zhonghua Wai Ke Za Zhi.2009; 47(6): 454-56.
  • 21. Özdil A, Turhan K, Çakan A, Çağırıcı U. Bronşektazide uzun dönem cerrahi tedavi sonuçları: hastaların düşünceleri nedir? İzm Göğ Has Derg. 2007; 21(1):11-5

SURGICAL TREATMENT OF BRONCHIECTASIS: SHORT AND LONG TERM RESULTS OF 45 PATIENTS

Year 2014, Volume: 28 Issue: 1, 31 - 37, 01.05.2014

Abstract

Bronchiectasis generally develops from pulmonary infections and bronchial obstruction. It is still a serious health problem in devoloping countries as our own.The aim of this retrospective study was to present our surgical experiences of managing bronchiectasis with results of short and long term follow-up. The files of 45 patients who underwent surgery for bronchiectasis in our clinic between January 2003 and March 2011 were reviewed retrospectively. The demographic features, symptoms, etiology, resection type, mortality, morbidity and follow-up results of patients were recorded and evaluated. There were 23(51,1%) female and 22 (48,9%) male patients and the average patient age was 30,3 years (ranged from 6 to 63 years). Symptoms were copious amount of purulent sputum in 35 patients, expectoration of foul-smelling sputum in 30 patients, dyspnea in 20 patients and cough in all patients. A total of 34 lobectomies, three lobectomies with segmentectomy, six segmentectomies, one bilobectomy and five wedge resections were carried out. Postoperative early complications were seen in 17 patients.There was no death in our study group. Follow-up was completed in 39 patients with a mean period of 24 months.Six patient could not be followed up properly. Symptoms disappeared in 28 patients, improved in seven, unchanged or worsened in four. In bronchiectasis treatment, first choice is medical therapy. Surgical treatment is a good option in case of failured medical therapy, especially with localised disease. Surgical resection for bronchiectasis can be performed with acceptable morbidity and mortality. For bilateral diffuse disease, lung transplation is an hot-button and promising treatment choice.

References

  • 1. Kavukçu Ş. Akciğerin süpüratif hastalıkları, In: Ökten İ, ed. Göğüs Cerrahisi, 1 Baskı, cilt 2, Ankara: Sim Matbaacılık,2003;1001-9.
  • 2. Yıldızeli B, Yüksel M. Pnömoni, akciğer apsesi ve bronşektazi. In: Yüksel M, Kalaycı G; eds. Göğüs Cerrahisi.1.Baskı İstanbul: Özlem Grafik Matbaacılık,2001;659-76.
  • 3. Miller JI. Bronchiectasis. In: Shields TW, LoCicero J, Reed CE, Feins RH, editors. General Thoracic Surgery. 7 th ed. Philedelphia: Lippincotts, Williams and Wilkins; 2000. p. 1117-9.
  • 4. Baklanli K, Genç O, Dakak M, et al. Surgical management of bronchiectasis: analysing and short-term results in 238 patient. Eur J Cardiothorac Surg. 2003; 24(5): 699-702.
  • 5. Kutlay H, Cangir AK, Enön S, et al. Surgica treatment in bronchiectasis: analysis of 166 patients. Eur J Cardiothorac Surg. 2002; 21(4): 634-7.
  • 6. Özdemir Ö. Bronşektazi. Solunum Sistemi ve Hastalıkları. Numanoğlu N ed. Ankara: Antıp AŞ, 1997:421-31.
  • 7. Doğan R, Alp M, Kaya S, et al. Surgical treatment of bronchiectasis: a collective review of 487 cases. Thorac Cardiovasc Surg. 1989; 37(3): 183-6.
  • 8. Nikolaizik WH, Warner JO. Etiology of chronic suppurative lung disease. Arch Dis Child 1994; 70: 141-2.
  • 9. Karasu S. Bronşektazide cerrahi tedavinin yeri. Uzmanlık Tezi. Ankara: Atatürk Göğüs Hastalıkları Ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi,2003.
  • 10. Bruggen-Bogaarts B, Bruggen H, Waes P, et al. Screening for bronchiectasis. A comparative study between chest radiography and highresolution CT. Chest 1996; 109: 608-11
  • 11. Ooi GC, Khong PL, Chan-Yeung M, et al. Highresolution CT quantification of bronchiectasis: Clinical and functional correlation. Radiology 2002; 225(3): 663-72.
  • 12. Kang EY, Miller RR, Muller NL. Bronchiectasis: Comprasion of preoperative thin-section CT and pathologic findins in resected specimens. Radiology 1995; 195: 649-54
  • 13. Prieto D, Bernardo J, Matos MJ, et al. Sugery for bronchiectasis. Eur J Cardiothorac Surg 2001; 20: 19-23
  • 14. Laros CD, Van Den Bosch CM, Westermann CJ, et al. Resection of more than 10 lung segments: A 30-year survey of bronchiectatic patients. J Thorac Cardiovasc Surg. 1988; 95(1): 119-23.
  • 15. Hayes D Jr, Meyer KC. Lung transplantation for advanced bronchiectasis. Semin Respir Crit Care Med. 2010; 31(2): 123-38
  • 16. Beirne PA, Banner NR, Khaghani A, et al. Lung transplantation for non-cystic fibrosis bronchiectasis: analysing of a 13 –year experience. J Heart Lung Transplant. 2005; 24(10): 1530-35.
  • 17. Nathan JA, Sharples LD, Exley AR, et al. The outcomes of lung transplantation in patients with bronchiectasis and antibody deficiency. J Heart Lung Transplant. 2005; 24(10): 1517-21.
  • 18. Groen H, Van der Bij W, Koeter GH, Tenvergert EM. Cost-effectiveness of lung transplantation in relation to type of end-stage pulmonary disease. Am J Transplant. 2004; 4(7): 1155-62.
  • 19. Zhang P, Zhang F, Jiang S, et al. Video-assisted thoracic surery for bronchiectasis. Ann Thorac Surg. 2011; 91(1): 239-43.
  • 20. Yang F, Li Y, Liu J, et al. Video-assisted thoracoscopic lobectomy for benign pulmonary disease. Zhonghua Wai Ke Za Zhi.2009; 47(6): 454-56.
  • 21. Özdil A, Turhan K, Çakan A, Çağırıcı U. Bronşektazide uzun dönem cerrahi tedavi sonuçları: hastaların düşünceleri nedir? İzm Göğ Has Derg. 2007; 21(1):11-5
There are 21 citations in total.

Details

Other ID JA24JE58YZ
Journal Section Case Report
Authors

Kerim Tülüce This is me

İlknur Aytekin This is me

Cüneyt Kurul This is me

Abdullah İrfan Taştepe This is me

Publication Date May 1, 2014
Published in Issue Year 2014 Volume: 28 Issue: 1

Cite

APA Tülüce, K., Aytekin, İ., Kurul, C., Taştepe, A. İ. (2014). BRONŞEKTAZİNİN CERRAHİ TEDAVİSİ: 45 HASTANIN ERKEN VE GEÇ DÖNEM SONUÇLARI. İzmir Göğüs Hastanesi Dergisi, 28(1), 31-37.