DESIGN AND STRUCTURAL ANALYSIS OF 3D-PRINTED POROUS POLYLACTIC ACID/HYDROXYAPATITE SCAFFOLDS

Year 2024, , 71 - 79, 30.04.2024

Nurcan Acar M. Kürşat Terzi , Adem Yılmaz , Rümeysa Aydoğdu Büşra Mutlu , Şeyma Duman

https://doi.org/10.46519/ij3dptdi.1347163

Abstract

Different designs of three-dimensional (3D) structures have gained increasingly significant in bone tissue engineering. For scaffolds, having appropriate porosity and adequate mechanical properties is crucial. The porosity and mechanical properties of scaffolds are higly influenced by their 3D modeled design. By evaluating the mechanical properties of scaffolds with various designs, it can be confirmed that they could serve as an important platform for the regeneration of damaged bone tissue. In this study, a diverse range of unit cells and lattice structures featuring different pore structures of polylactic acid (PLA)/hydroxyapatite (HA) based scaffolds were modeled and designed. Structural analyses of the designed models were conducted in a simulation environment and their mechanical properties were compared with similar studies. The results suggest that PLA/HA-based scaffolds with different designs hold high potential for applications in bone tissue engineering.

Keywords

Polylactic Acid, Scaffold, Design, Structural Analysis, Mechanical Strength.

DESIGN AND STRUCTURAL ANALYSIS OF 3D-PRINTED POROUS POLYLACTIC ACID/HYDROXYAPATITE SCAFFOLDS

Abstract

Different designs of three-dimensional (3D) structures have gained increasing importance in the field of bone tissue engineering. Appropriate porosity and adequate mechanical properties are essen-tial requirements for scaffolds. The porosity and mechanical properties of the scaffolds higly depend on their 3D-modeled design. By analyzing the mechanical properties of scaffolds of different designs, it can be confirmed that it can be an important potential platform for regenerating damaged bone tis-sue. In this study, a wide variety of unit cells and lattice structures with different pore structures of polylactic acid (PLA)/hydroxyapatite (HA) based scaffolds were modeled and designed. Structural analyzes of the designed models were carried out in the simulation environment and their mechanical properties were compared with similar studies. According to the obtained results, PLA/HA-based scaffolds with different designs are thought to have high potential for bone tissue engineering appli-cations.

Keywords

Polylactic acid, Scaffold, Design, Structural analysis, Mechanical strength

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