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Abstract

Aim It has been shown that heart rate recovery index is an independent risk factor for cardiovascular mortality. It has been reported in most epidomiologic studies that an elevated associated with cardiovascular diseases. The aim of this study was to investigate whether there is a relationship between heart rate recovery index and neutrophillymphocyte ratio. Materials and Methods A total of 238 patients who underwent coronary angiography due to abnormal treadmill exercise test results and who admitted to Cardiology Department of Faculty of Medicine at Namık Kemal University were evaluated retrospectively. heart rate recovery index was

Keywords

• Heart rate recovery index, neutrophil

Nötrofil Lenfosit Oranının Kalp Hızı Toparlanma İndeksi ile İlişkisi

Öz

GİRİŞ Kalp Hızı Toparlanma İndeksinin kardiyovasküler mortalitenin bağımsız bir risk faktörü olduğu gösterilmiştir. Yükselen nötrofil-lenfosit oranının bir çok epidemiylojik çalışmada Kardiyovasküler hastalıklar ile kuvvetli ilişki içinde olduğu bildirilmiştir. Bu çalışmanın amacı Kalp Hızı Toparlanma İndeksi ile nötrofil-lenfosit oranı arasındaki ilişkiyi araştırmaktırır. MATERYAL ve METOD Namık Kemal Üniversitesi Araştırma ve Uygulama Hastanesi Kardiyoloji Polikliniği’ne, başvuran, anormal efor testi nedeniyle koroner anjiyografi yapılan 238 hasta retrospektif olarak değerlendirilmiştir. Egzersiz sırasındaki maksimum kalp hızından istirahatin 1. dakikasındaki kalp hızı çıkartılarak 18 atım ve altı değerler anormal olarak kabul edildi. SONUÇLAR Kalp Hızı Toparlanma İndeksinin normal olanlar ile anormal olan bireyler arasıda Nötrofil sayısı ve nötrofil-lenfosit oranı karşılaştırılmasında istatistiksel olarak anlamlı bir ilişkili olduğunu tespit edilmiştir. (sırasıyla p=0,027 ve p=0.000). TARTIŞMA Sonuç olarak mevcut bulgularımız anormal Kalp Hızı Toparlanma İndeksli hastalarda artan nötrofil-lenfosit oranının kardiyovasküler mortalite ve morbidite ile ilşkili olabileceğini düşündürmektedir. Gelecekte yapılacak prospektif çalışmalar ile egzersizin anormal Kalp Hızı Toparlanma İndeksli bireylerde nötrofil-lenfosit oranının üzerine etkisinin araştırılması bu konuda daha kesin deliller sağlayacaktır.

Anahtar Kelimeler

• Kalp hızı toparlanma İndeksi, nötrofillenfosit oranı, kardiyovasküler mortalite

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