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Abstract

The idea of substituting the non-functioning human larynx with another one insipired many researchers and numerous studies associated with this topic have been performed so far. Following operations performed due to malignancies, the survival rates of the patients increased and hence quality of life became gradually more important. This is especially important for laryngectomees who had increased life spans due to of progresses in medical and surgical treatment of laryngeal cancer. As a consequence, the idea of performing a laryngeal transplantation to improve the quality of life is becoming more substantial. In this review, we aimed to recall the history of the laryngeal transplat procedure, overview the indications and ethico-medicolegal issues and discuss the opinions related with the future of the procedure in details

Keywords

• Laryngeal transplantation, quality of life, reinnervation, medico-legal

2014 Yılında Larengeal Transplantasyonun Geldiği Nokta

Öz

İşlev görmeyen insan larenksinin yerine başka bir larenksin konulabilmesi düşüncesi son 50 yıldan beri bu konuda yapılan birçok çalışmaya ilham konusu olmuştur. Kanser ameliyatları sonrasında hastaların sağ kalımlarının artmasının yanı sıra, yaşam kalitelerinin de artması gittikçe ön plana çıkmaktadır. Bu durum özellikle cerrahi ve medikal tedavilerdeki gelişmelere paralel olarak yaşam sürelerinde artış sağlanmış olan total larenjektomili hastalar için çok önemlidir. Sonuç olarak, yaşam kalitesini artırmak amacıyla larenks tranplantasyonu yapılması düşüncesi önemli hale gelmektedir. Bu derlemede bu konu ile ilgili tarihsel gelişim sürecinin yanı sıra, endikasyonlara ve etiko-mediko-legal konulara değinilmesi ve larengeal transplantasyonun geleceği ile ilgili görüşlerin detaylı bir şekilde ele alınması amaçlanmıştır.

Anahtar Kelimeler

• Larengeal transplant, yaşam kalitesi, reinnervasyon, mediko-legal

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