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The Implication of the Preoperative Platelet to Lymphocyte Ratio in the Diagnosis of Laryngeal Carcinoma

Year 2016, Volume: 4 Issue: 2, 0 - 0, 04.10.2016

Abstract

Objectives: To investigate the diagnostic implication of the platelet to lymphocyte ratio (PLR) as a biological marker in predicting the malignancy of space-occupying laryngeal lesions.
Methods: The medical records of the patients who underwent an operation for a laryngeal pathology between September 2010 and January 2015 in a tertiary referral center were retrospectively reviewed. For the control group, 50 age and sex matched patients were selected among the patients who underwent septoplasty. Preoperative platelet to lymphocyte ratio was calculated for each subject in the malignant, benign and control groups.
Results: Comparison of the three groups using Kruskal Wallis test showed that there was no statistical difference between the groups. (p>0.05, p=0.871) The median PLR of the patients in the malignant group was lower than the benign group and the control group.
Conclusions: In conclusion, squamous laryngeal carcinoma was not found to be associated with an increased preoperative PLR. Our findings indicated that, PLR may not be used as a biological marker for the diagnosis of laryngeal malignancy.
Keywords: laryngeal cancer; platelet; platelet to lymphocyte ratio; predictive role; differential diagnosis

Year 2016, Volume: 4 Issue: 2, 0 - 0, 04.10.2016

Abstract

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Details

Journal Section Araştırma Makaleleri
Authors

Tolga Ersözlü This is me

Oral Burak Demirel This is me

Publication Date October 4, 2016
Published in Issue Year 2016 Volume: 4 Issue: 2

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APA Ersözlü, T., & Demirel, O. B. (2016). The Implication of the Preoperative Platelet to Lymphocyte Ratio in the Diagnosis of Laryngeal Carcinoma. International Journal of Basic and Clinical Medicine, 4(2).
AMA Ersözlü T, Demirel OB. The Implication of the Preoperative Platelet to Lymphocyte Ratio in the Diagnosis of Laryngeal Carcinoma. International Journal of Basic and Clinical Medicine. October 2016;4(2).
Chicago Ersözlü, Tolga, and Oral Burak Demirel. “The Implication of the Preoperative Platelet to Lymphocyte Ratio in the Diagnosis of Laryngeal Carcinoma”. International Journal of Basic and Clinical Medicine 4, no. 2 (October 2016).
EndNote Ersözlü T, Demirel OB (October 1, 2016) The Implication of the Preoperative Platelet to Lymphocyte Ratio in the Diagnosis of Laryngeal Carcinoma. International Journal of Basic and Clinical Medicine 4 2
IEEE T. Ersözlü and O. B. Demirel, “The Implication of the Preoperative Platelet to Lymphocyte Ratio in the Diagnosis of Laryngeal Carcinoma”, International Journal of Basic and Clinical Medicine, vol. 4, no. 2, 2016.
ISNAD Ersözlü, Tolga - Demirel, Oral Burak. “The Implication of the Preoperative Platelet to Lymphocyte Ratio in the Diagnosis of Laryngeal Carcinoma”. International Journal of Basic and Clinical Medicine 4/2 (October 2016).
JAMA Ersözlü T, Demirel OB. The Implication of the Preoperative Platelet to Lymphocyte Ratio in the Diagnosis of Laryngeal Carcinoma. International Journal of Basic and Clinical Medicine. 2016;4.
MLA Ersözlü, Tolga and Oral Burak Demirel. “The Implication of the Preoperative Platelet to Lymphocyte Ratio in the Diagnosis of Laryngeal Carcinoma”. International Journal of Basic and Clinical Medicine, vol. 4, no. 2, 2016.
Vancouver Ersözlü T, Demirel OB. The Implication of the Preoperative Platelet to Lymphocyte Ratio in the Diagnosis of Laryngeal Carcinoma. International Journal of Basic and Clinical Medicine. 2016;4(2).