Aim The aim of the present study was to determine the antimicrobial resistance rates of Enterococcus strains isolated from various clinical specimens obtained from the patients admitted to our hospital between November 2011 and November 2012. Materials and Methods Of the 117 strains studied, 62 (53%) were Enterococcus faecium and 55 (47%) were Enterococcus faecalis. The antibiotic susceptibility of isolated strains were defined according to the criteria of the Clinical and Laboratory Standards Institute. Results A total of 97% of the strains were found to be resistant to ampicillin, 47% were resistant to ciprofloxacin and moxifloxacin. Five strains were found intermediate or resistant to linezolid. No resistance was shown to vancomycin, teicoplanin, and tigecycline. High level resistance to gentamycin was observed in 42% and to streptomisin in 53% of isolates. Conclusion In the present study, E. faecalis isolates were determined to be more resistant to all antibiotic evaluated, however, no significant differences were found between two species in terms of resistance (p>0.05 for each antibiotic). Data provided by our study may be directive for treatment choise in cases with enterococci-caused infections
Bu çalışmada Kasım 2011-Kasım 2012 arasında hastanemize baş¬vuran hastaların çeşitli klinik örneklerinden izole edilen enterokok suşlarının antibiyotiklere direnç oranları incelenmiştir. VITEK-2 otomatize sistem ile incelenen 117 suşun 62’si (%53) Enterococcus faecium, 55’i (%47) Enterococcus faecalis olarak tanımlanmış, antibi¬yotik duyarlılık oranları disk difüzyon yöntemi ile The Clinical and Laboratory Standards Institute (CLSI) standartlarının enterokok türleri için önerdiği zon çapları dik¬kate alınarak belirlenmiştir. Çalışmaya alınan suşların %97’si ampisiline, %47’si siprofloksasin ve moksifloksasine dirençli bulunmuştur. Toplam 5 suş linezolide orta duyarlı veya dirençli bulunmuştur. Vankomisin, teikoplanin ve tigesikline direnç saptanmamıştır. Yüksek düzey aminoglikozid direnci ise gentamisin için %42, streptomisin için %53 olarak saptanmıştır.
Primary Language | Turkish |
---|---|
Journal Section | Araştırma Makaleleri |
Authors | |
Publication Date | June 4, 2015 |
Published in Issue | Year 2013 Volume: 1 Issue: 2 |