Evaluation of the Wound Healing Potential of Teucrioside

Year 2018, Volume: 2 Issue: 1, 16 - 19, 13.03.2018

Seçil Erden Tayhan , Sema Bilgin Mahfuz Elmastaş

https://doi.org/10.32571/ijct.345050

Cited By: 10

https://izlik.org/JA99XP29BP

Abstract

Herbal medicines are being
used for primary health care due to their efficacy, safety and less side
effects. Teucrium genus is a member of the Lamiaceae family, which is
a medicinal plant have been used in traditional medicine, especially for wound
healing and inflammatory conditions. Teucroside, 9′-decarboxyrosmarinic
acid-4′-O-α-rhamnosyl-(1‴→6‴)-O-β-galactosyl-(1‴→4″)-O-α-rhamnoside is a
natural phenolic compund which is isolated and identified from of Teucrium genus. In this study, because of bioactive
properties of Teucrioside, it was
decided to examine its potential wound healing effect. Wound healing process was investigated by in vitro scratch assay which was an easy, inexpensive and well developed method to measure cell migration. In this context, firstly,
cell viability was determined by MTT assay and the results were evaluated to
find effective concentration for wound
healing. Then the cells were incubated for 48 h with
extract with defined concentration. Finally, after 48 hours of incubation with teucroside, the
wound healing was calculated as 47%. When the data were compared with untreated
control (49%), it was concluded that teucroside had not wound healing potential.

Keywords

: Teucrioside , Lamiaceae , wound healing , scratch assay

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