Theoretical approach using DFT and muscle relaxant effects of 5-Chloroisatin Derivatives

Zineb Tribak; Alae Chda; Mohammed Khalid Skalli; Amal Haoudi; Youssef Kandri Rodi; Omar Senhaji; El Mokhtar Essassi; Rachid Ben Cheikh; Kaouakib El Abida

doi:10.32571/ijct.446539

EN

Theoretical approach using DFT and muscle relaxant effects of 5-Chloroisatin Derivatives

Abstract

A new series of 5-Chloroisatin derivatives were synthesied and characterises with different characterization methods such as ¹H-NMR and1³C-NMR spectroscopy, and then tested for their myorelaxant activity. Computational investigations of the compounds 1a-3a, 2b and 4b on the muscle-relaxing effects performance were performed by using the DFT method with B3LYP functional. The result of descriptors calculation revealed that the theoretical approach was in good agreement with the reported experimental data.

Keywords

5-Chloroisatin derivatives,B3LYP functional and DFT method,synthesis,myorelaxant effects

References

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Details

Primary Language

English

Subjects

Chemical Engineering

Journal Section

Research Article

Authors

Zineb Tribak ^*
0000-0002-2169-9856

Alae Chda This is me

Mohammed Khalid Skalli This is me

Amal Haoudi This is me

Youssef Kandri Rodi This is me

Omar Senhaji This is me

El Mokhtar Essassi This is me

Rachid Ben Cheikh This is me

Kaouakib El Abida This is me

Publication Date

December 28, 2018

Submission Date

July 21, 2018

Acceptance Date

October 6, 2018

Published in Issue

Year 2018 Volume: 2 Number: 2

DOI

https://doi.org/10.32571/ijct.446539

IZ

https://izlik.org/JA58UX23DT

Cite

RIS / Bibtex

APA

Tribak, Z., Chda, A., Skalli, M. K., Haoudi, A., Rodi, Y. K., Senhaji, O., Essassi, E. M., Cheikh, R. B., & El Abida, K. (2018). Theoretical approach using DFT and muscle relaxant effects of 5-Chloroisatin Derivatives. International Journal of Chemistry and Technology, 2(2), 105-115. https://doi.org/10.32571/ijct.446539

AMA

1.Tribak Z, Chda A, Skalli MK, et al. Theoretical approach using DFT and muscle relaxant effects of 5-Chloroisatin Derivatives. Int. J. Chem. Technol. 2018;2(2):105-115. doi:10.32571/ijct.446539

Chicago

Tribak, Zineb, Alae Chda, Mohammed Khalid Skalli, et al. 2018. “Theoretical Approach Using DFT and Muscle Relaxant Effects of 5-Chloroisatin Derivatives”. International Journal of Chemistry and Technology 2 (2): 105-15. https://doi.org/10.32571/ijct.446539.

EndNote

Tribak Z, Chda A, Skalli MK, Haoudi A, Rodi YK, Senhaji O, Essassi EM, Cheikh RB, El Abida K (December 1, 2018) Theoretical approach using DFT and muscle relaxant effects of 5-Chloroisatin Derivatives. International Journal of Chemistry and Technology 2 2 105–115.

IEEE

[1]Z. Tribak et al., “Theoretical approach using DFT and muscle relaxant effects of 5-Chloroisatin Derivatives”, Int. J. Chem. Technol., vol. 2, no. 2, pp. 105–115, Dec. 2018, doi: 10.32571/ijct.446539.

ISNAD

Tribak, Zineb - Chda, Alae - Skalli, Mohammed Khalid - Haoudi, Amal - Rodi, Youssef Kandri - Senhaji, Omar - Essassi, El Mokhtar - Cheikh, Rachid Ben - El Abida, Kaouakib. “Theoretical Approach Using DFT and Muscle Relaxant Effects of 5-Chloroisatin Derivatives”. International Journal of Chemistry and Technology 2/2 (December 1, 2018): 105-115. https://doi.org/10.32571/ijct.446539.

JAMA

1.Tribak Z, Chda A, Skalli MK, Haoudi A, Rodi YK, Senhaji O, Essassi EM, Cheikh RB, El Abida K. Theoretical approach using DFT and muscle relaxant effects of 5-Chloroisatin Derivatives. Int. J. Chem. Technol. 2018;2:105–115.

MLA

Tribak, Zineb, et al. “Theoretical Approach Using DFT and Muscle Relaxant Effects of 5-Chloroisatin Derivatives”. International Journal of Chemistry and Technology, vol. 2, no. 2, Dec. 2018, pp. 105-1, doi:10.32571/ijct.446539.

Vancouver

1.Zineb Tribak, Alae Chda, Mohammed Khalid Skalli, Amal Haoudi, Youssef Kandri Rodi, Omar Senhaji, El Mokhtar Essassi, Rachid Ben Cheikh, Kaouakib El Abida. Theoretical approach using DFT and muscle relaxant effects of 5-Chloroisatin Derivatives. Int. J. Chem. Technol. 2018 Dec. 1;2(2):105-1. doi:10.32571/ijct.446539

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