Osteogenesis Imperfecta

Year 2022, Volume: 2 Issue: 1, 66 - 68, 29.04.2022

Betül Yazmacı Muhammed Demir Mehmet Sinan Doğan

Abstract

Osteogenesis Imperfecta (OI), also known as glass bone disease; It is an autosomal dominant inherited disease
with a prevalence of approximately 1/15,000-1/20,000, with clinical findings such as increased bone fragility, blue
sclera, dental disorders, dentinogenesis imperfecta, hearing loss, ligamentous laxity, long bone fractures and
deformities. In OI, which is the most common cause of genetically-induced osteoporosis, long bone fractures and
vertebral compression fractures are seen after a simple trauma. In OI patients, dental anomalies are seen clinically as
dentinogenesis imperfecta (DI), malocclusion, mandibular prognathism, and decrease in vertical dimension. In this
article, it is aimed to evaluate an important bone disease such as osteogenesis imperfecta by emphasizing its clinical
and oral findings.

Keywords

Osteogenesis imperfecta, blue sclera, brittle bone disease, dentinogenesis imperfecta.

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