Year 2021,
, 1 - 11, 28.04.2021
Dilek Atik
,
Basar Cander
,
Cesareddin Dikmetaş
,
Serkan Dogan
,
İbrahim Çaltekin
,
Levent Albayrak
,
Emre Gökçen
,
Bensu Bulut
References
- [1] TUIK, Ölüm Nedeni İstatistikleri, http://www.tuik.gov.tr. 2017.
- [2] World Health Organization, Global Health Estimates 2016: Deaths by Cause, Age, Sex, by Country and by Region, 2000-2016. Geneva.2018.
- [3] Turk, G., Ustun, R., “Kronik Obstrüktif Akciğer Hastalığı (KOAH) Olan Bireylerin Bakım Bağımlılığının Belirlenmesi”, Dokuz Eylül Üniversitesi Hemşirelik Fakültesi Elektronik Dergisi , 11 (1), 19-25, 2018.
- [4] Karan,M.A., “Demografik değişimle ilgili hastalık yükü”, Sağlık Düşüncesi ve Tıp Kültürü Dergisi, 44, 18-21, 2017.
- [5] Sherry, L., Murphy, B.S., Kenneth, D., Kochanek, M.A., Xu, J., Arias, E., Mortality in the United States, 2014, NCHS Data Brief, 228, 1-8,2015.
- [6] Umut, S., Kronik Obstrüktif Akciğer Hastalığında Atak. Toplumdan Edinilmiş Enfeksiyonlara Pratik Yaklaşımlar. İ.Ü. Cerrahpasa Tıp Fakültesi Sürekli Tıp Egitimi Etkinlikleri Sempozyum Dizisi, İstanbul, 2008; 61, pp.117-128.
- [7] Uysal, H., “Kronik Obstrüktif Akciğer Hastalığı. N. Enç içinde”, İç Hastalıkları Hemşireliği. Nobel Tıp Kitabevleri, İstanbul. 2014,pp. 138-151.
- [8] Turk Toraks Dernegi(TTD). Türk Toraks Dernegi'nin GOLD 2017 kronik obstrüktif akciger hastalığı (KOAH) raporuna bakışı. Accepted date: 08.11.2017. http://toraks.org.tr.2017.
- [9] Vogelmeier, C.F., Criner, G.J., Martinez, F.J., Anzueto, A., Barnes, P.J., Bourbeau, J et al., “Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD executive summary” Am J Respir Crit Care Med., 195,557–582, 2017.
- [10] Heulens, N., Korf, H., Cielen, N et al. “Vitamin D deficiency exacerbates COPD-like characteristics in the lungs of cigarette smoke-exposed mice”, Respir Res., 16: 110,2015.
- [11] Vestbo, J., Hurd, S.S., Alvar, G., Agustı, A.G., Jones, P.W., Vogelmeier, C et al. “Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease GOLD Executive Summary”, American Journal Of Respiratory And Critical Care Medicine, 187,346-365, 2015.
- [12] Lips, P.,”Vitamin D physiology”, Prog Biophys Mol Biol., 92,4-8,2006.
- [13] Akman, Ö.A., “1 - 16 Yaş Arası Çocuklarda D Vitamini Düzeyi ve Buna Etki Eden Faktörlerin Belirlenmesi” Gazi Üniversitesi Tıp Fakültesi, Tıpta Uzmanlık Tezi Ankara, Şubat pp.1-5.2009.
- [14] Li, Y.C., Qiao, G., Uskokovic, M., Xiang, W., Zheng, W., Kong, J., “Vitamin D: negative endocrine regulator of the renin-angiotensin system and blood pressure”, J Steroid Biochem Mol Biol., 89-90,387-92,2004.
- [15] Holick, M.F.,”vitamin D a millenium perspective”, J Cell Biochem., 88(2),296-307,2003.
- [16] Hahn, S., Haselhorst, U., Tan, S., Quadbeck, B., Schmidt, M., Roesler, S et al. “Low 25-hydroxyvitamin D concentrations are associated with insulin resistance and obesity in women with polycystic ovary syndrome”, Exp Clin Endocrinol Diabetes, 114,577-83,2006.
- [17] Holick, M.F., “Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease” Am J Clin Nutr., 80,1678-88,2004.
- [18] Holick, M.F., “Vitamin D: extraskeletal health (Review)” Endocrinol Metab Clin North Am., 39: 381-40;2010.
[19] Bikle, D., “Nonclassic of Actions vitamin D” JCEM., 94, 26-34,2009.
- [20] Rafiq, R., Thijs, W., Prein, R., Jongh, R.T., Taube, C.,,”Hiemstra PS et al. Associations of Serum 25(OH)D Concentrations with Lung Function, Airway Inflammation and Common Cold in the General Population”,Nutrients, 10(35),2-13,2018.
- [21] Tanakol, R., “Kalsiyum, fosfor ve kemik metabolizması: kalsiyumu regule eden hormonlar. Endokrinoloji, Metabolizma Hastalıkları (Kemik ve Mineral Metabolizma Hastalıkları): Ergin Sencer, editör. Nobel Kitabevleri,1-3,.2000.
- [22] Skaaby, T., Husemoen, L.L., Pisinger, C. et al. “Vitamin D status and causespecific mortality: A general population study”, PLoS One, 7, 52423,2012.
- [23] Pludowski, P., Holick, M.F., Pilz, S., Wagner, C.L., Hollis, B.W., Grant, W.B, et al,. “Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality- a review of recent evidence” Autoimmun Rev, 12, 976-89,2013.
- [24] Jones, P.W., Harding, G., Berry, P., Wiklund, I., Chen, W.H., Leidy, N.K., “Development and first validation of the COPD Assessment Test”, Eur Respir J.,34(3),648-54,2009.
- [25] Yorgancioğlu, A., Polatlı, M., Aydemir, Ö. et al. “KOAH Değerlendirme Testinin Türkçe Geçerlilik ve Güvenirliliği” Tüberküloz ve Toraks Dergisi, 60(4),314-20,2012.
- [26] Holman, W.J. (ed.), Dawlish, D(ed). Medical Research Coincil Committee On Research İnto Bronchitis. Instructions For Use Of The Questionnaire On Respiratory Symptoms. London, Medical Research Council, 1966.
- [27] Bestall, J.C., Paul, E.A., Garrod, R., “Usefulness Of The Medical Research Council (MRC) Dyspnea Scale As A Measure Of Disability İn Patients With Chronic Obstructive Pulmonary Disease”, Thorax, 54, 581-586,1999.
- [28] Turk Toraks Derneği. “Kronik Obstrüktif Akciğer Hastalığı Tanı, Tedavi ve Koruma Rapor” Türk Toraks Dergisi, 15 (2), 19-29,2014.
- [29] ATS statement. “Standarts for the diagnosis and care of patients with chronic obstructive pulmonary disease”, Am J Crit Care Med., 1995;152,77-120,1995.
- [30] Hansdottir, S., Monnick, M.M., Hinde, S.L., Lovan, N., Look, D.C., Hunnighake, G.W., “Respiratory epithelial cells convert inactive vitamin D to its active form potential effects on host defense”, J Immunol., 181,7090-9,2008.
- [31] Janssens, W., MaThieu, C., Boonen, S., Decramer, M., “Vitamin D deficiency and chronic obstructive pulmonary disease: a vicious circle,in Vitamins and Hormones” ed. L. Gerald (NewYork,NY:Academic Press), 86,379–399,2011.
- [32] Deniz, S.,Özboduç, A.D.,Serpoyraz, F., Polat, G., Alizaroglu, D., “The Effect Of Treatment For Vıtamın D Deffıcıency On Anxıety And Depressıon In Group A Copd Patıents”, İzmir Göğüs Hastanesi Dergisi, 32( 2),75-81,2018.
- [33] Shaheen, S.O., Jameson, K.A., Robinson, S.M., Boucher, B.J., Syddall, H.E., Sayer, A.A., Cooper, C., Holloway, J.W., “Dennison EM. Relationship of vitamin D status to adult lung function and copd”, Thorax, 66,692–698,2011.
- [34] Erdinc, E., Polatlı, M., Kocabas, A., Yıldırım, N., Gurgun, A., Saryal, S. et al. “Turkish Thoracic Society Chronic Obstructive Pulmonary Disease Diagnosis and Treatment Consensus Guidelines”, Türk Toraks Dergisi, 11,1-64,2010.
- [35] Black, P.N., Scragg, R.,”Relationship between serum 25- hydroxyvitamin D and pulmonary function in the third national health and nutrition examination survey” Chest, 128, 3792-3798,2005.
- [36] Lehouck, A., Mathieu, C., Carremans, C., et al. “High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial”, Ann Intern Med.,156:105-114,2012.
- [37] Lange, N.E., Sparrow, D., Vokonas, P., Litonjua, A.A.,”Vitamin D deficiency, Smoking, and Lung Function in the Normative Aging Study”, Am J Respir Crit Care Med., 1(186), 616-621,2012.
- [38] Rafiq, R., Prins, H.J., Boersma, W.G., Daniels, J.M., den Heijer, M., Lips, P et al. “Effects of daily vitamin D supplementation on respiratory muscle strength and physical performance in vitamin D-deficient COPD patients: a pilot trial”, Int J Chron Obstruct Pulmon Dis., 12,2583-2592,2017.
- [39] Martineau, A.R., James, W., Hooper, R.L., Barnes, N.C., Jolliffe, D.A., Greiller, C.L et al., “Vitamin D supplementation in patients with chronic obstructive pulmonary disease (ViDiCO): a multicentre, double-blind, randomised controlled trial” Lancet Respir Med., 3(2),120– 130,2015.
- [40] Martineau, A.R., Jolliffe, D.A., Hooper, R.L., Greenberg, L., Aloia, J.F., Bergman, P., Dubnov-Raz, G., Esposito, S., Ganmaa, D., Ginde, A.A. et al., “Vitamin D supplementation to prevent acute respiratorytract infections: Systematic review and meta-analysis of individual participant data”, BMJ., 356:i6583,2017.
- [41] Pourrashid, M.H., Dastan, F., Salamzadeh, J., Eslaminejad, A., Edalatifard, M., “Role of Vitamin D Replacement on Health Related Quality of Life in Hospitalized Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease” Iran J Pharm Res.,17(2),801-810,2018.
EVALUATION OF THE RELATIONSHIP BETWEEN VITAMIN D LEVELS IN COPD PATIENTS WITH ACUTE RESPIRATORY FAILURE
Year 2021,
, 1 - 11, 28.04.2021
Dilek Atik
,
Basar Cander
,
Cesareddin Dikmetaş
,
Serkan Dogan
,
İbrahim Çaltekin
,
Levent Albayrak
,
Emre Gökçen
,
Bensu Bulut
Abstract
COPD with the development of inflammation in the alveoli as a result of exposure of harmful gases to the bronchi and bronchioles in the lungs, irreversible airflow restriction and respiratory symptoms occur. In our study;It is aimed to evaluate the serum D vitamin level in COPD patients with acute respiratory failure and to investigate the effect of vitamin D in COPD stages. This study is a prospective cross-sectional study. The study was conducted with a total of 75 COPD patient groups and 65 control groups. GOLD score, CAT score and Mmrc score were used in the study. Kruskal-Wallis H test and Mann-Whitney U test were used for statistical analysis.The results were evaluated in terms of p <0.05 significance level. According to the results of our study, vitamin D level in acute exacerbation was lower in patients with acute obstructive pulmonary disease than in the control group. According to the results obtained in our study, when CAT scores, Mmrc scores, vitamin D levels and gold scores,which are the measured assessment for chronic obstructive pulmonary disease patients, are evaluated; With increasing vitamin D deficiency, patient clinics become more severe. We believe that patients diagnosed with COPD add vitamin D to their treatment protocols according to their vitamin D levels and their vital activities will increase while reducing the severity of COPD.
References
- [1] TUIK, Ölüm Nedeni İstatistikleri, http://www.tuik.gov.tr. 2017.
- [2] World Health Organization, Global Health Estimates 2016: Deaths by Cause, Age, Sex, by Country and by Region, 2000-2016. Geneva.2018.
- [3] Turk, G., Ustun, R., “Kronik Obstrüktif Akciğer Hastalığı (KOAH) Olan Bireylerin Bakım Bağımlılığının Belirlenmesi”, Dokuz Eylül Üniversitesi Hemşirelik Fakültesi Elektronik Dergisi , 11 (1), 19-25, 2018.
- [4] Karan,M.A., “Demografik değişimle ilgili hastalık yükü”, Sağlık Düşüncesi ve Tıp Kültürü Dergisi, 44, 18-21, 2017.
- [5] Sherry, L., Murphy, B.S., Kenneth, D., Kochanek, M.A., Xu, J., Arias, E., Mortality in the United States, 2014, NCHS Data Brief, 228, 1-8,2015.
- [6] Umut, S., Kronik Obstrüktif Akciğer Hastalığında Atak. Toplumdan Edinilmiş Enfeksiyonlara Pratik Yaklaşımlar. İ.Ü. Cerrahpasa Tıp Fakültesi Sürekli Tıp Egitimi Etkinlikleri Sempozyum Dizisi, İstanbul, 2008; 61, pp.117-128.
- [7] Uysal, H., “Kronik Obstrüktif Akciğer Hastalığı. N. Enç içinde”, İç Hastalıkları Hemşireliği. Nobel Tıp Kitabevleri, İstanbul. 2014,pp. 138-151.
- [8] Turk Toraks Dernegi(TTD). Türk Toraks Dernegi'nin GOLD 2017 kronik obstrüktif akciger hastalığı (KOAH) raporuna bakışı. Accepted date: 08.11.2017. http://toraks.org.tr.2017.
- [9] Vogelmeier, C.F., Criner, G.J., Martinez, F.J., Anzueto, A., Barnes, P.J., Bourbeau, J et al., “Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD executive summary” Am J Respir Crit Care Med., 195,557–582, 2017.
- [10] Heulens, N., Korf, H., Cielen, N et al. “Vitamin D deficiency exacerbates COPD-like characteristics in the lungs of cigarette smoke-exposed mice”, Respir Res., 16: 110,2015.
- [11] Vestbo, J., Hurd, S.S., Alvar, G., Agustı, A.G., Jones, P.W., Vogelmeier, C et al. “Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease GOLD Executive Summary”, American Journal Of Respiratory And Critical Care Medicine, 187,346-365, 2015.
- [12] Lips, P.,”Vitamin D physiology”, Prog Biophys Mol Biol., 92,4-8,2006.
- [13] Akman, Ö.A., “1 - 16 Yaş Arası Çocuklarda D Vitamini Düzeyi ve Buna Etki Eden Faktörlerin Belirlenmesi” Gazi Üniversitesi Tıp Fakültesi, Tıpta Uzmanlık Tezi Ankara, Şubat pp.1-5.2009.
- [14] Li, Y.C., Qiao, G., Uskokovic, M., Xiang, W., Zheng, W., Kong, J., “Vitamin D: negative endocrine regulator of the renin-angiotensin system and blood pressure”, J Steroid Biochem Mol Biol., 89-90,387-92,2004.
- [15] Holick, M.F.,”vitamin D a millenium perspective”, J Cell Biochem., 88(2),296-307,2003.
- [16] Hahn, S., Haselhorst, U., Tan, S., Quadbeck, B., Schmidt, M., Roesler, S et al. “Low 25-hydroxyvitamin D concentrations are associated with insulin resistance and obesity in women with polycystic ovary syndrome”, Exp Clin Endocrinol Diabetes, 114,577-83,2006.
- [17] Holick, M.F., “Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease” Am J Clin Nutr., 80,1678-88,2004.
- [18] Holick, M.F., “Vitamin D: extraskeletal health (Review)” Endocrinol Metab Clin North Am., 39: 381-40;2010.
[19] Bikle, D., “Nonclassic of Actions vitamin D” JCEM., 94, 26-34,2009.
- [20] Rafiq, R., Thijs, W., Prein, R., Jongh, R.T., Taube, C.,,”Hiemstra PS et al. Associations of Serum 25(OH)D Concentrations with Lung Function, Airway Inflammation and Common Cold in the General Population”,Nutrients, 10(35),2-13,2018.
- [21] Tanakol, R., “Kalsiyum, fosfor ve kemik metabolizması: kalsiyumu regule eden hormonlar. Endokrinoloji, Metabolizma Hastalıkları (Kemik ve Mineral Metabolizma Hastalıkları): Ergin Sencer, editör. Nobel Kitabevleri,1-3,.2000.
- [22] Skaaby, T., Husemoen, L.L., Pisinger, C. et al. “Vitamin D status and causespecific mortality: A general population study”, PLoS One, 7, 52423,2012.
- [23] Pludowski, P., Holick, M.F., Pilz, S., Wagner, C.L., Hollis, B.W., Grant, W.B, et al,. “Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality- a review of recent evidence” Autoimmun Rev, 12, 976-89,2013.
- [24] Jones, P.W., Harding, G., Berry, P., Wiklund, I., Chen, W.H., Leidy, N.K., “Development and first validation of the COPD Assessment Test”, Eur Respir J.,34(3),648-54,2009.
- [25] Yorgancioğlu, A., Polatlı, M., Aydemir, Ö. et al. “KOAH Değerlendirme Testinin Türkçe Geçerlilik ve Güvenirliliği” Tüberküloz ve Toraks Dergisi, 60(4),314-20,2012.
- [26] Holman, W.J. (ed.), Dawlish, D(ed). Medical Research Coincil Committee On Research İnto Bronchitis. Instructions For Use Of The Questionnaire On Respiratory Symptoms. London, Medical Research Council, 1966.
- [27] Bestall, J.C., Paul, E.A., Garrod, R., “Usefulness Of The Medical Research Council (MRC) Dyspnea Scale As A Measure Of Disability İn Patients With Chronic Obstructive Pulmonary Disease”, Thorax, 54, 581-586,1999.
- [28] Turk Toraks Derneği. “Kronik Obstrüktif Akciğer Hastalığı Tanı, Tedavi ve Koruma Rapor” Türk Toraks Dergisi, 15 (2), 19-29,2014.
- [29] ATS statement. “Standarts for the diagnosis and care of patients with chronic obstructive pulmonary disease”, Am J Crit Care Med., 1995;152,77-120,1995.
- [30] Hansdottir, S., Monnick, M.M., Hinde, S.L., Lovan, N., Look, D.C., Hunnighake, G.W., “Respiratory epithelial cells convert inactive vitamin D to its active form potential effects on host defense”, J Immunol., 181,7090-9,2008.
- [31] Janssens, W., MaThieu, C., Boonen, S., Decramer, M., “Vitamin D deficiency and chronic obstructive pulmonary disease: a vicious circle,in Vitamins and Hormones” ed. L. Gerald (NewYork,NY:Academic Press), 86,379–399,2011.
- [32] Deniz, S.,Özboduç, A.D.,Serpoyraz, F., Polat, G., Alizaroglu, D., “The Effect Of Treatment For Vıtamın D Deffıcıency On Anxıety And Depressıon In Group A Copd Patıents”, İzmir Göğüs Hastanesi Dergisi, 32( 2),75-81,2018.
- [33] Shaheen, S.O., Jameson, K.A., Robinson, S.M., Boucher, B.J., Syddall, H.E., Sayer, A.A., Cooper, C., Holloway, J.W., “Dennison EM. Relationship of vitamin D status to adult lung function and copd”, Thorax, 66,692–698,2011.
- [34] Erdinc, E., Polatlı, M., Kocabas, A., Yıldırım, N., Gurgun, A., Saryal, S. et al. “Turkish Thoracic Society Chronic Obstructive Pulmonary Disease Diagnosis and Treatment Consensus Guidelines”, Türk Toraks Dergisi, 11,1-64,2010.
- [35] Black, P.N., Scragg, R.,”Relationship between serum 25- hydroxyvitamin D and pulmonary function in the third national health and nutrition examination survey” Chest, 128, 3792-3798,2005.
- [36] Lehouck, A., Mathieu, C., Carremans, C., et al. “High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial”, Ann Intern Med.,156:105-114,2012.
- [37] Lange, N.E., Sparrow, D., Vokonas, P., Litonjua, A.A.,”Vitamin D deficiency, Smoking, and Lung Function in the Normative Aging Study”, Am J Respir Crit Care Med., 1(186), 616-621,2012.
- [38] Rafiq, R., Prins, H.J., Boersma, W.G., Daniels, J.M., den Heijer, M., Lips, P et al. “Effects of daily vitamin D supplementation on respiratory muscle strength and physical performance in vitamin D-deficient COPD patients: a pilot trial”, Int J Chron Obstruct Pulmon Dis., 12,2583-2592,2017.
- [39] Martineau, A.R., James, W., Hooper, R.L., Barnes, N.C., Jolliffe, D.A., Greiller, C.L et al., “Vitamin D supplementation in patients with chronic obstructive pulmonary disease (ViDiCO): a multicentre, double-blind, randomised controlled trial” Lancet Respir Med., 3(2),120– 130,2015.
- [40] Martineau, A.R., Jolliffe, D.A., Hooper, R.L., Greenberg, L., Aloia, J.F., Bergman, P., Dubnov-Raz, G., Esposito, S., Ganmaa, D., Ginde, A.A. et al., “Vitamin D supplementation to prevent acute respiratorytract infections: Systematic review and meta-analysis of individual participant data”, BMJ., 356:i6583,2017.
- [41] Pourrashid, M.H., Dastan, F., Salamzadeh, J., Eslaminejad, A., Edalatifard, M., “Role of Vitamin D Replacement on Health Related Quality of Life in Hospitalized Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease” Iran J Pharm Res.,17(2),801-810,2018.