Antioxidant, Antialzheimer, Antiurease Enzyme Activities of Marrubium vulgare L. (Lamiaceae)

Handan Kurtulmuş Sancak; Selami Selvi; Turgut Taşkın

Antioxidant, Antialzheimer, Antiurease Enzyme Activities of Marrubium vulgare L. (Lamiaceae)

Abstract

Marrubium vulgare L. is a perennial herbaceous plant belonging to the Lamiaceae family. This species, which usually grows in regions with a Mediterranean climate, has gray-green hairy leaves and small white flowers. It is widely used in traditional medicine in the treatment of respiratory diseases, digestive problems and cough. M. vulgare has a strong antioxidant capacity thanks to the phenolic compounds, flavonoids and diterpenoids it contains. Thanks to these properties, it is among the plants that attract attention in the pharmaceutical and food industries as a natural antioxidant source. The ethanol: water extract exhibited higher antioxidant capacity than the ethanol extract, as evidenced by its stronger DPPH radical scavenging activity (61.60%), greater CUPRAC value (4.36 mM Trolox equivalents/mg extract), and enhanced FRAP reducing power (0.64 mM FeSO₄/mg extract). The total phenolic content was found to be comparable between the two extracts. As expected, the reference antioxidants ascorbic acid and demonstrated superior antioxidant activities compared to the plant extracts. In enzyme inhibition analyses, the ethanol extract showed more pronounced anticholinesterase activity (20.911±2.324), while the ethanol: water extract showed higher antiurease inhibition (27.615±2.092). Overall, the findings indicate that the solvent system significantly affects the biological activity profile of M. vulgare.

Keywords

Ethical Statement

I testify on behalf of all co-authors that our article submitted followed ethical principles in publishing.

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Details

Primary Language

English

Subjects

Botany (Other)

Journal Section

Research Article

Authors

Handan Kurtulmuş Sancak ^*
0000-0003-3531-8548
Türkiye

Selami Selvi
0000-0002-9959-6945
Türkiye

Turgut Taşkın
0000-0001-8475-6478
Türkiye

Early Pub Date

March 26, 2026

Publication Date

March 26, 2026

Submission Date

February 22, 2026

Acceptance Date

March 11, 2026

Published in Issue

Year 2026 Number: Advanced Online Publication

IZ

https://izlik.org/JA86DM22WN

Cite

RIS / Bibtex

APA

Kurtulmuş Sancak, H., Selvi, S., & Taşkın, T. (2026). Antioxidant, Antialzheimer, Antiurease Enzyme Activities of Marrubium vulgare L. (Lamiaceae). International Journal of Nature and Life Sciences, Advanced Online Publication, 10-17. https://izlik.org/JA86DM22WN

AMA

1.Kurtulmuş Sancak H, Selvi S, Taşkın T. Antioxidant, Antialzheimer, Antiurease Enzyme Activities of Marrubium vulgare L. (Lamiaceae). Int J Nature Life Sci. 2026;(Advanced Online Publication):10-17. https://izlik.org/JA86DM22WN

Chicago

Kurtulmuş Sancak, Handan, Selami Selvi, and Turgut Taşkın. 2026. “Antioxidant, Antialzheimer, Antiurease Enzyme Activities of Marrubium Vulgare L. (Lamiaceae)”. International Journal of Nature and Life Sciences, no. Advanced Online Publication: 10-17. https://izlik.org/JA86DM22WN.

EndNote

Kurtulmuş Sancak H, Selvi S, Taşkın T (March 1, 2026) Antioxidant, Antialzheimer, Antiurease Enzyme Activities of Marrubium vulgare L. (Lamiaceae). International Journal of Nature and Life Sciences Advanced Online Publication 10–17.

IEEE

[1]H. Kurtulmuş Sancak, S. Selvi, and T. Taşkın, “Antioxidant, Antialzheimer, Antiurease Enzyme Activities of Marrubium vulgare L. (Lamiaceae)”, Int J Nature Life Sci, no. Advanced Online Publication, pp. 10–17, Mar. 2026, [Online]. Available: https://izlik.org/JA86DM22WN

ISNAD

Kurtulmuş Sancak, Handan - Selvi, Selami - Taşkın, Turgut. “Antioxidant, Antialzheimer, Antiurease Enzyme Activities of Marrubium Vulgare L. (Lamiaceae)”. International Journal of Nature and Life Sciences. Advanced Online Publication (March 1, 2026): 10-17. https://izlik.org/JA86DM22WN.

JAMA

1.Kurtulmuş Sancak H, Selvi S, Taşkın T. Antioxidant, Antialzheimer, Antiurease Enzyme Activities of Marrubium vulgare L. (Lamiaceae). Int J Nature Life Sci. 2026;:10–17.

MLA

Kurtulmuş Sancak, Handan, et al. “Antioxidant, Antialzheimer, Antiurease Enzyme Activities of Marrubium Vulgare L. (Lamiaceae)”. International Journal of Nature and Life Sciences, no. Advanced Online Publication, Mar. 2026, pp. 10-17, https://izlik.org/JA86DM22WN.

Vancouver

1.Handan Kurtulmuş Sancak, Selami Selvi, Turgut Taşkın. Antioxidant, Antialzheimer, Antiurease Enzyme Activities of Marrubium vulgare L. (Lamiaceae). Int J Nature Life Sci [Internet]. 2026 Mar. 1;(Advanced Online Publication):10-7. Available from: https://izlik.org/JA86DM22WN