Review
BibTex RIS Cite

A review of Moroccan Medicinal Plants Used in the Treatment of Hypertension

Year 2022, Volume: 6 Issue: 1, 48 - 78, 01.06.2022
https://doi.org/10.47947/ijnls.1010197

Abstract

The incidence of hypertension is very high in human societies and its treatment is the most important priority in many countries. Knowledge of the plants that are used may provide insight on their properties, for further exploration. This study aimed to collect the knowledge on traditional medicine for the treatment of hypertension in different regions of Morocco. We reviewed 145 research publications based on data from the six explored regions of Morocco published until August 2021 in various journals. This was achieved using literature databases: Google, Google Scholar, PubMed, Medline, Science Direct and Researchgate. The findings of this study indicated that 23 plants have been reported to possess antihypertensive activities in in vivo / in vitro experiments, while 81 plants had not been studied for such an activity. Plants from the Lamiaceae, Asteraceae and Apiaceae families were used most often. Leaves were the plant parts used most often. Decoction was the main preparation method. Twenty three plants have been explored experimentally for their antihypertensive activity. This review provides baseline data for plant species used to treat hypertension in Morocco and provides new areas of research on the antihypertensive effect of these plants.

References

  • Abushouk, A. I., Salem, A. M. A., & Abdel-Daim, M. M. (2017). Berberis vulgaris for cardiovascular disorders: a scoping literature review. Iranian Journal of Oasic Medical Sciences, 20(5), 503- 510.
  • Agarwal, U., Pathak, D. P., Kapoor, G., Bhutani, R., Roper, R., Gupta, V., & Kant R. (2017). Review on Cuminum Cyminum—nature’s magical seeds. Journal of Chemical and Pharmaceutical Research, 9(9), 180-187.
  • Agyare, C., T. Appiah, Y.D. Boakye, & J. Apenteng, 2017. Petroselinum crispum: A Review. In: Medicinal Spices and Vegetables from Africa: Therapeutic Potential against Metabolic, Inflammatory, Infectious and Systemic Diseases, Kuete, V. (Ed.). Chapter 25, Elsevier, New York, USA., pp: 527-547.
  • Ahmad, A., Husain, A., Mujeeb, M., Khan, S. A., Najmi, A. K., Siddique, N. A., Damanhouri, Z. A., & Anwar, F. (2013). A review on therapeutic potential of Nigella sativa: A miracle herb. Asian Pacific Journal of Tropical Biomedicine, 3(5), 337-352.
  • Ahmad, S., Mir N., & Sultan, S. (2018). White-berry mistletoe (Viscum album L.): a hemiparasitic plant: occurrence and ethnobotanical use in Kashmir. Journal of Pharmacognosy and Phytochemistry, 7(1), 1831-1833.
  • Al-Qattan, K., Alnaqeeb, M., & Ali, M. (1999). The antihypertensive effect of garlic (Allium sativum) in the rat two-kidney–one-clip Goldblatt model. Journal of Ethnopharmacology, 66(2), 217-222.
  • Al-Snafi, A. E. (2016a). Medical importance of Anthemis nobilis (Chamaemelum nobile)-a review. Asian Journal of Pharmaceutical Science & Technology, 6(2), 89-95.
  • Al-Snafi, A. E. (2016b). The pharmacological activities of Cuminum cyminum-A review. IOSR Journal of Pharmacy, 6(6), 46-65.
  • Alam, K., Hoq, O., & Uddin, S. (2016). Medicinal plant Allium sativum. A review. Journal of Medicinal Plants Studies, 4(6), 72-79.
  • Ali, B. H., Wabel, N. A., & Blunden, G. (2005). Phytochemical, pharmacological and toxicological aspects of Hibiscus sabdariffa L.: a review. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 19(5), 369-375.
  • Allaq, A. A., Sidik, N. J., Abdul-Aziz, A., & Ahmed, I. A. (2020). Cumin (Cuminum cyminum L.): A review of its ethnopharmacology, phytochemistry. Biomedical Research and Therapy, 7(9), 4016-4021.
  • Amer, B., Juvik, O. J., Dupont, F., Francis, G. W., & Fossen, T. (2012). Novel aminoalkaloids from European mistletoe (Viscum album L.). Phytochemistry Letters, 5(3), 677-681.
  • Araniti, F., Lupini, A., Sunseri, F., & Abenavoli, M. R. (2017). Allelopatic potential of Dittrichia viscosa (L.) W. Greuter mediated by VOCs: A physiological and metabolomic approach. Plos One, 12(1), e0170161.
  • Arroyo, A. I., Pueyo, Y., Pellissier, F., Ramos, J., Espinosa-Ruiz, A., Millery, A., & Alados, C. L. (2018). Phytotoxic effects of volatile and water soluble chemicals of Artemisia herba-alba. Journal of Arid Environments, 151, 1-8.
  • Asdadi, A., Hamdouch, A., Gharby, S., & Hassani, L. M. I. (2020). Chemical characterization of essential oil of Artemisia herba-alba asso and his possible potential against covid-19. Journal of Analytical Sciences and Applied Biotechnology, 2(2), 2067-2072.
  • Assaidi, A., Legssyer, A., Berrichi, A., Aziz M., Mekhfi, H., Bnouham, M., & Ziyyat A. (2014). Hypotensive property of Chenopodium ambrosioides in anesthetized normotensive rats. Journal of Complementary and Integrative Medicine, 11(1), 1-7.
  • Awaad, A. A., El‐Meligy, R. M., Zain, G. M., Safhi, A. A., AL Qurain, N. A., Almoqren, S. S., Zain, Y. M., Sesh Adri, V. D., & Al‐Saikhan, F. I. (2018). Experimental and clinical antihypertensive activity of Matricaria chamomilla extracts and their angiotensin‐converting enzyme inhibitory activity. Phytotherapy Research, 32(8), 1564-1573.
  • Bahadır, Ş., Kadioğlu, İ., & Onaran, A. (2017). Antifungal activity of parasitic plant (Orobanche ramosa L. Cuscuta campestris Yunck. and Viscum album L.) extracts against some plant pathogenic fungi. Türkiye Herboloji Dergisi, 20(1), 61-69.
  • Baharvand-Ahmadi, B., & Asadi-Samani, M. (2017). A mini-review on the most important effective medicinal plants to treat hypertension in ethnobotanical evidence of Iran. Journal of Nephropharmacology, 6(1), 3-8.
  • Baharvand-Ahmadi, B., Bahmani, M., Tajeddini, P., Rafieian-Kopaei, M., & Naghdi, N. (2016). An ethnobotanical study of medicinal plants administered for the treatment of hypertension. Journal of Renal Injury Prevention, 5(3), 123-128.
  • Balaraman, R., Dangwal, S., & Mohan, M. (2006). Antihypertensive effect of trigonella foenum-greacum. seeds in experimentally induced hypertension in rats. Pharmaceutical Biology, 44(8), 568-575.
  • Benbott, A., Bahri, L., Boubendir, A., & Yahia, A. (2013). Study of the chemical components of Peganum harmala and evaluation of acute toxicity of alkaloids extracted in the Wistar albino mice. Journal of Material and Environmental Science, 4, 558-565.
  • Bento, I., & Pereira, J. A. (2011). Arbutus unedo L. and its benefits on human health. J Food Nutr Res, 5073-85.
  • Bertella, A., Benlahcen, K., Abouamama, S., Pinto, D. C., Maamar, K., Kihal, M., & Silva, A. M. (2018). Artemisia herba-alba Asso. essential oil antibacterial activity and acute toxicity. Industrial Crops and Products, 116, 137-143.
  • Bezerra, J. W. A., Costa, A. R., de Freitas, M. A., Rodrigues, F. C., de Souza, M. A., da Silva, A. R. P., Dos Santos, A. T. L., Linhares, K. V., Coutinho, H. D. M., & de Lima, Silva J. R. (2019). Chemical composition, antimicrobial, modulator and antioxidant activity of essential oil of Dysphania ambrosioides (L.) Mosyakin & Clemants. Comparative Immunology, Microbiology and Infectious Diseases, 65, 58-64.
  • Bilal, A., Jahan, N., Ahmed, A., Bilal, S. N., Habib, S., & Hajra, S. (2012). Phytochemical and pharmacological studies on Ocimum basilicum Linn-A review. International Journal of Current Research and Review, 4(23), 73-83.
  • Boutkhil, S., El Idrissi, M., Amechrouq, A., Chbicheb, A., Chakir, S., & El Badaoui, K. (2009). Chemical composition and antimicrobial activity of crude, aqueous, ethanol extracts and essential oils of Dysphania ambrosioides (L.) Mosyakin & Clemants. Acta Botanica Gallica, 156(2), 201-209.
  • Bouzidi, A., Mahdeb, N., & Kara, N. (2011). Toxicity studies of alkaloids of seeds of Datura stramonium and synthesis alkaloids in male rats. Journal of Medicinal Plants Research, 5(15), 3421-3431.
  • Bystrická, J., Musilová, J., Vollmannová, A., Timoracká, M., & Kavalcová, P. (2013). Bioactive components of onion (Allium cepa L.) - A Review. Acta Alimentaria, 42(1), 11-22.
  • Camejo-Rodrigues, J., Ascensao, L., Bonet, M. À., & Valles, J. (2003). An ethnobotanical study of medicinal and aromatic plants in the Natural Park of “Serra de São Mamede” (Portugal). Journal of Ethnopharmacology, 89(2-3), 199-209.
  • Cavero, R., Akerreta, S., & Calvo, M. (2011a). Pharmaceutical ethnobotany in Northern Navarra (Iberian Peninsula). Journal of Ethnopharmacology, 133(1), 138-146.
  • Cavero, R., Akerreta, S., & Calvo, M. (2011b). Pharmaceutical ethnobotany in the middle Navarra (Iberian Peninsula). Journal of Ethnopharmacology, 137(1), 844-855.
  • Charef, M., Yousfi, M., Saidi, M., & Stocker, P. (2008). Determination of the fatty acid composition of acorn (Quercus), Pistacia lentiscus seeds growing in Algeria. Journal of the American Oil Chemists' Society, 85(10), 921-924.
  • Cortés-Rojas, D. F., de Souza C. R. F., & Oliveira W. P. (2014). Clove (Syzygium aromaticum): a precious spice. Asian Pacific Journal of Tropical Biomedicine, 4(2), 90-96.
  • Da-Costa-Rocha, I., Bonnlaender, B., Sievers, H., Pischel, I., & Heinrich, M. (2014). Hibiscus sabdariffa L.–A phytochemical and pharmacological review. Food Chemistry, 165, 424-443.
  • De Wet, H., Ramulondi, M., & Ngcobo, Z. (2016). The use of indigenous medicine for the treatment of hypertension by a rural community in northern Maputaland, South Africa. South African Journal of Botany, 103, 78-88.
  • Dehkordi, F. R., & Kamkhah, A. F. (2008). Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension. Fundamental & Clinical Pharmacology, 22(4), 447-452.
  • Dias-Martins A. M., Pessanha K. L. F., Pacheco S., Rodrigues J. A. S., & Carvalho C. W. P. (2018). Potential use of pearl millet (Pennisetum glaucum (L.) R. Br.) in Brazil: Food security, processing, health benefits and nutritional products. Food Research International, 109, 175-186.
  • Douira, A., & Zidane, L. (2015). Étude ethnobotanique des plantes médicinales utilisées dans le traitement du diabète, et des maladies cardiaques dans la région d’Izarène (Nord du Maroc). Journal of Applied Biosciences, 86(1), 7940–7956.
  • Eddouks, M., Maghrani, M., Lemhadri, A., Ouahidi, M.-L., & Jouad, H. (2002). Ethnopharmacological survey of medicinal plants used for the treatment of diabetes mellitus, hypertension and cardiac diseases in the south-east region of Morocco (Tafilalet). Journal of Ethnopharmacology, 82(2-3), 97-103.
  • El-Saber Batiha, G., Magdy Beshbishy, A., G Wasef L., Elewa Y. H., A Al-Sagan A., El-Hack A., Mohamed E., Taha, A. E., M Abd-Elhakim Y., & Prasad Devkota, H. (2020). Chemical constituents and pharmacological activities of garlic (Allium sativum L.): A review. Nutrients, 12(3), 872. https://doi.org/10.3390/nu12030872
  • Falana H., Nofal W., & Nakhleh H. (2014). A review article Lepidium sativum (Garden cress). In: Pharm-D Program, College of Nursing, Pharmacy and Health Professions, Birzeit University, Birzeit, Palestine, 1-8.
  • Fatehi‐Hassanabad, Z., Jafarzadeh, M., Tarhini, A., & Fatehi, M. (2005). The antihypertensive and vasodilator effects of aqueous extract from Berberis vulgaris fruit on hypertensive rats. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 19(3), 222-225.
  • Gaire, B. P., & Subedi, L. (2013). A review on the pharmacological and toxicological aspects of Datura stramonium L. Journal of Integrative Medicine, 11(2), 73-79.
  • Galavi, A., Hosseinzadeh, H., & Razavi, B. M. (2021). The effects of Allium cepa L. (onion) and its active constituents on metabolic syndrome: A review. Iranian Journal of Basic Medical Sciences, 24(1), 3-16. https://doi.org/10.22038/ijbms.2020.46956.10843.
  • Gbekley, H. E., Karou, S. D., Katawa, G., Tchacondo, T., Batawila, K., Ameyapoh, Y., & Simpore, J. (2018). Ethnobotanical survey of medicinal plants used in the management of hypertension in the maritime region of Togo. African Journal of Traditional, Complementary and Alternative Medicines, 15(1), 85-97.
  • Ghanbari, R., Anwar, F., Alkharfy, K. M., Gilani, A.-H., & Saari, N. (2012). Valuable nutrients and functional bioactives in different parts of olive (Olea europaea L.)—a review. International Journal of Molecular Sciences, 13(3), 3291-3340.
  • Grauso, L., Cesarano, G., Zotti M., Ranesi, M., Sun, W., Bonanomi, G., & Lanzotti, V. (2019). Exploring Dittrichia viscosa (L.) Greuter phytochemical diversity to explain its antimicrobial, nematicidal and insecticidal activity. Phytochemistry Reviews, 19, 659-689.
  • Gupta, V., Mittal, P., Bansal, P., Khokra, S. L., & Kaushik, D. (2010). Pharmacological potential of Matricaria recutita-A review. International Journal of Pharmaceutical Sciences and Drug Research, 2(1), 12-16.
  • Hakkou, Z., Maciuk, A., Leblais, V., Bouanani, N. E., Mekhfi, H., Bnouham, M., Aziz, M., Ziyyat, A., Rauf, A., & Hadda, T. B. (2017). Antihypertensive and vasodilator effects of methanolic extract of Inula viscosa: Biological evaluation and POM analysis of cynarin, chlorogenic acid as potential hypertensive. Biomedicine & Pharmacotherapy, 93, 62-69.
  • Hameed, I. H., Mohammed, G. J., & Kamal, S. A. (2018). A review: Uses and Pharmacological activity of Matricaria chamomilla. Indian Journal of Public Health Research and Development, 9(3), 200-205.
  • Horner, O., Cheap-Charpentier, H., Cachet, X., Perrot, H., Lédion, J., Gelus, D., Pécoul, N., Litaudon, M., & Roussi, F. (2017). Antiscalant properties of Herniaria glabra aqueous solution. Desalination, 409, 157-162.
  • Hosseinzadeh, S., Jafarikukhdan, A., Hosseini, A., & Armand, R. (2015). The application of medicinal plants in traditional and modern medicine: a review of Thymus vulgaris. International Journal of Clinical Medicine, 6(9), 635-642.
  • Hussein, H. J., Hameed, I. H., & Hadi, M. Y. (2017). A Review: Anti-microbial, Anti-inflammatory effect and Cardiovascular effects of Garlic: Allium sativum. Research Journal of Pharmacy and Technology, 10(11), 4069-4078.
  • Idm’hand, H., Msanda, F., & Cherifi, K. (2019). Ethnopharmacological Documentation of Medicinal Plants Used in the Traditional Treatment of Hypertension in Tarfaya Province, Morocco. International Journal of Pharmacology, Phytochemistry and Ethnomedicine, 14, 16-39.
  • Imanshahidi, M., & Hosseinzadeh, H. (2008). Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytotherapy Research, 22(8), 999-1012.
  • Imenshahidi, M., & Hosseinzadeh, H. (2016). Berberis vulgaris and berberine: an update review. Phytotherapy Research, 30(11), 1745-1764.
  • Joshi, B. C., Mukhija, M., & Kalia, A. N. (2014). Pharmacognostical review of Urtica dioica L. International Journal of Green Pharmacy, 8(4), 201-209.
  • Jouad, H., Haloui, M., Rhiouani, H., El Hilaly, J., & Eddouks, M. (2001). Ethnobotanical survey of medicinal plants used for the treatment of diabetes, cardiac and renal diseases in the North centre region of Morocco (Fez–Boulemane). Journal of Ethnopharmacology, 77(2-3), 175-182.
  • Kalaivani, P., Saranya, R. B., Ramakrishnan, G., Ranju, V., Sathiya, S., Gayathri, V., Thiyagarajan, L. K., Venkhatesh, J. R., Babu, C. S., & Thanikachalam, S. (2013). Cuminum cyminum, a dietary spice, attenuates hypertension via endothelial nitric oxide synthase and NO pathway in renovascular hypertensive rats. Clinical and Experimental Hypertension, 35(7), 534-542.
  • Kang, S.-J., & Chung, S.-K. (2012). Antioxidant and antimicrobial activities of Korean mistletoe (Viscum album var. coloratum) extracts against food poisoning bacteria. Korean Journal of Food Preservation, 19(6), 919-924.
  • Karou, S. D., Tchacondo, T., Djikpo Tchibozo M. A., Abdoul-Rahaman, S., Anani, K., Koudouvo, K., Batawila, K., Agbonon, A., Simpore, J., & de Souza, C. (2011). Ethnobotanical study of medicinal plants used in the management of diabetes mellitus and hypertension in the Central Region of Togo. Pharmaceutical Biology, 49(12), 1286-1297.
  • Kaur, K., & Kaushal, S. (2019). Phytochemistry and pharmacological aspects of Syzygium aromaticum: A review. J Pharmacogn Phytochem, 8, 398-406.
  • Kazemian, H., Ghafourian, S., Heidari, H., Amiri, P., Yamchi, J. K., Shavalipour, A., Houri, H., Maleki, A., & Sadeghifard N. (2015). Antibacterial, anti-swarming and anti-biofilm formation activities of Chamaemelum nobile against Pseudomonas aeruginosa. Revista da Sociedade Brasileira de Medicina Tropical, 48(4), 432-436.
  • Kazemian, H., Ghafourian, S., Sadeghifard, N., Houshmandfar, R., Badakhsh, B., Taji, A., Shavalipour, A., Mohebi, R., Ebrahim-Saraie, H. S., & Houri, H. (2018). In vivo antibacterial and wound healing activities of Roman chamomile (Chamaemelum nobile). Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious Disorders), 18(1), 41-45.
  • Kensara, O. A., ElSawy, N. A., El-Shemi, A. G., & Header, E. A. (2013). Thymus vulgaris supplementation attenuates blood pressure and aorta damage in hypertensive rats. Journal of Medicinal Plants Research, 7(11), 669-676.
  • Khan, T., Ali S., Qayyum, R., Hussain, I., Wahid, F., & Shah, A. J. (2016). Intestinal and vascular smooth muscle relaxant effect of Viscum album explains its medicinal use in hyperactive gut disorders and hypertension. BMC Complementary and Alternative Medicine, 16(1), 1-8.
  • Khan, Y., Panchal, S., Vyas, N., Butani, A., & Kumar, V. (2007). Olea europaea: a phyto-pharmacological review. Pharmacognosy Reviews, 1(1), 114-118.
  • Kienle, G. S., & Kiene, H. (2010). Influence of Viscum album L (European mistletoe) extracts on quality of life in cancer patients: a systematic review of controlled clinical studies. Integrative Cancer Therapies, 9(2), 142-157. Kovarovič, J., Bystricka, J., Vollmannova, A., Toth, T., & Brindza, J. (2019). Biologically valuable substances in garlic (Allium sativum L.)–A review. Journal of Central European Agriculture, 20(1), 292-304.
  • Kozachok, S., Marchyshyn, S., Ostapchuk, A., & Zavyalova, L. (2016). Monosaccharide composition of Herniaria glabra L. and Herniaria polygama J. Gay. Current Issues in Pharmacy and Medical Sciences, 29(3), 142-144.
  • Kozachok, S., Pecio, Ł., Kolodziejczyk-Czepas, J., Marchyshyn, S., Nowak, P., Mołdoch, J., & Oleszek, W. (2018). γ-Pyrone compounds: flavonoids and maltol glucoside derivatives from Herniaria glabra L. collected in the Ternopil region of the Ukraine. Phytochemistry, 152, 213-222.
  • Kozachok, S., Pecio, Ł., Orhan, I. E., Deniz, F. S. S., Marchyshyn, S., & Oleszek, W. (2020). Reinvestigation of Herniaria glabra L. saponins and their biological activity. Phytochemistry, 169, 112162.
  • Leung, A. A., Daskalopoulou, S. S., Dasgupta, K., McBrien, K., Butalia, S., Zarnke, K. B., Nerenberg, K., Harris, K. C., Nakhla M., & Cloutier L. (2017). Hypertension Canada's 2017 guidelines for diagnosis, risk assessment, prevention, and treatment of hypertension in adults. Canadian Journal of Cardiology, 33(5), 557-576.
  • Liu, X., Wang, X., Chen, Z., Ye, J., Liao, Y., Zhang, W., Chang, J., & Xu, F. (2019). De novo assembly and comparative transcriptome analysis: novel insights into terpenoid biosynthesis in Chamaemelum nobile L. Plant Cell Reports, 38(1), 101-116.
  • Ljubuncic, P., Song, H., Cogan, U., Azaizeh, H., & Bomzon, A. (2005). The effects of aqueous extracts prepared from the leaves of Pistacia lentiscus in experimental liver disease. Journal of Ethnopharmacology, 100(1-2), 198-204.
  • Lyu, S.-Y., Rhim, J.-Y., Moon, Y.-S., Jung, S.-H., Lee, K.-Y., & Park, W.-B. (2002). Antitumor activities of extract of Viscum album var. coloratum Modified with Viscum album var. coloratum Agglutinin. Natural Product Sciences, 8(4), 155-161.
  • Maghrani, M., Zeggwagh, N.-A., Michel, J.-B., & Eddouks, M. (2005). Antihypertensive effect of Lepidium sativum L. in spontaneously hypertensive rats. Journal of Ethnopharmacology, 100(1-2), 193-197.
  • Mali, R. G., Mahajan, S. G., & Mehta, A. A. (2007). Lepidium sativum (Garden cress): a review of contemporary literature and medicinal properties. Oriental Pharmacy and Experimental Medicine, 7(4), 331-335.
  • Manohar, D., Viswanatha, G., Nagesh, S., Jain, V., & Shivaprasad, H. (2012). Ethnopharmacology of Lepidium sativum Linn (Brassicaceae): a review. International Journal of Phytothearpy Research, 2(1), 1-7.
  • Mansley, M. K., Ivy, J. R., & Bailey, M. A. (2016). The Evolution of Hypertension–Old Genes, New Concepts. Kidney International Reports, ISN Forefronts Symposium 2015, 1(3), 197-203.
  • Mehenni, C., Atmani-Kilani, D., Dumarçay, S., Perrin, D., Gérardin, P., & Atmani, D. (2016). Hepatoprotective and antidiabetic effects of Pistacia lentiscus leaf and fruit extracts. journal of Food and Drug Analysis, 24(3), 653-669.
  • Mezni, F., Shili, S., Ben Ali N., Larbi Khouja, M., Khaldi, A., & Maaroufi, A. (2016). Evaluation of Pistacia lentiscus seed oil and phenolic compounds for in vitro antiproliferative effects against BHK21 cells. Pharmaceutical biology, 54(5), 747-751.
  • Miguel, M. G., Faleiro M. L., Guerreiro A. C., & Antunes M. D. (2014). Arbutus unedo L.: chemical and biological properties. Molecules, 19(10), 15799-15823.
  • Miraj, S., & Alesaeidi, S. (2016). A systematic review study of therapeutic effects of Matricaria recuitta chamomile (chamomile). Electronic Physician, 8(9), 3024-3031.
  • Miraj, S., & Kiani, S. (2016). Study of pharmacological effect of Ocimum basilicum: A review. Der Pharmacia Lettre, 8(9), 276-280.
  • Mittal, M., Gupta, N., Parashar, P., Mehra, V., & Khatri, M. (2014). Phytochemical evaluation and pharmacological activity of Syzygium aromaticum: a comprehensive review. International Journal of Pharmacy and Pharmaceutical Sciences, 6(8), 67-72.
  • Mnif, S., & Aifa, S. (2015). Cumin (Cuminum cyminum L.) from traditional uses to potential biomedical applications. Chemistry & Biodiversity, 12(5), 733-742.
  • Mohamed, A. E.-H. H., El-Sayed, M., Hegazy, M. E., Helaly, S. E., Esmail, A. M., & Mohamed, N. S. (2010). Chemical constituents and biological activities of Artemisia herba-alba. Records of Natural Products, 4(1), 1-25.
  • Mohammed, M. J., Anand, U., Altemimi, A. B., Tripathi, V., Guo, Y., & Pratap-Singh, A. (2021). Phenolic Composition, Antioxidant Capacity and Antibacterial Activity of White Wormwood (Artemisia herba-alba). Plants, 10(1), 164. https://doi.org/10.3390/plants10010164
  • Mohebbati, R., & Abbasnezhad, A. (2020). Effects of Nigella sativa on endothelial dysfunction in diabetes mellitus: A review. Journal of ethnopharmacology, 252, 112585. https://doi.org/10.1016/j.jep.2020.112585
  • Mohsen, H., & Ali, F. (2009). Essential oil composition of Artemisia herba-alba from southern Tunisia. Molecules, 14(4), 1585-1594.
  • Mojiminiyi, F., Dikko, M., Muhammad, B., Ojobor, P., Ajagbonna, O., Okolo, R., Igbokwe, U., Mojiminiyi, U., Fagbemi, M., & Bello, S. (2007). Antihypertensive effect of an aqueous extract of the calyx of Hibiscus sabdariffa. Fitoterapia, 78(4), 292-297.
  • Morales-González, J. A., Madrigal-Bujaidar, E., Sánchez-Gutiérrez, M., Izquierdo-Vega, J. A., Valadez-Vega, M. d. C., Álvarez-González, I., Morales-González, Á., & Madrigal-Santillán, E. (2019). Garlic (Allium sativum L.): A brief review of its antigenotoxic effects. Foods, 8(8), 343. https://doi.org/10.3390/foods8080343
  • Morgado S., Morgado, M., Plácido, A. I., Roque, F., & Duarte, A. P. (2018). Arbutus unedo L.: From traditional medicine to potential uses in modern pharmacotherapy. Journal of Ethnopharmacology, 225, 90-102.
  • Murti, K., Panchal, M. A., Gajera, V., & Solanki, J. (2012). Pharmacological properties of Matricaria recutita: a review. Pharmacologia, 3(8), 348-351.
  • Mushtaq, M. N., & Akhtar, M. S. (2015). Blood pressure lowering effect of Pennisetum glaucum in rats. Bangladesh Journal of Pharmacology, 10(3), 494-499.
  • Mwanauta, R. W., Mtei, K. A., & Ndakidemi, P. A. (2014). Prospective bioactive compounds from Vernonia amygdalina, Lippia javanica, Dysphania ambrosioides and Tithonia diversifolia in controlling legume insect pests. Agricultural Sciences, 5(12), 1129.
  • Nambiar, V. S., Dhaduk, J., Sareen N., Shahu T., & Desai, R. (2011). Potential functional implications of pearl millet (Pennisetum glaucum) in health and disease. Journal of Applied Pharmaceutical Science, 1(10), 62.
  • Nathiya, S., Durga, M., & Devasena, T. (2014). Therapeutic role of Trigonella foenum-graecum [fenugreek]–a review. International Journal of Pharmaceutical Sciences Review and Research, 27(2), 74-80.
  • Niazi, M., Yari, F., & Shakarami, A. (2019). A Review of Medicinal Herbs in the Lamiaceae Family Used to Treat Arterial Hypertension. Entomology and Applied Science Letters, 6(1), 22-37.
  • Ofem, O., Eno, A., Imoru J., Nkanu E., Unoh F., & Ibu J. (2007). Effect of crude aqueous leaf extract of Viscum album (mistletoe) in hypertensive rats. Indian Journal of Pharmacology, 39(1), 15-19.
  • Olaiya, C. O., & Soetan, K. O. (2014). A review of the health benefits of fenugreek (Trigonella foenum-graecum L.): Nutritional, Biochemical and pharmaceutical perspectives. A merican Journal of Social Issues and Humanities, 43, 12.
  • Osei, Akoto, C., Acheampong, A., Boakye, Y. D., Naazo, A. A., & Adomah, D. H. (2020). Anti-inflammatory, antioxidant, and anthelmintic activities of Ocimum basilicum (Sweet Basil) fruits. Journal of Chemistry, 2153534, https://doi.org/10.1155/2020/2153534
  • Özcan, M. M., & Matthäus, B. (2017). A review: benefit and bioactive properties of olive (Olea europaea L.) leaves. European Food Research and Technology, 243(1), 89-99.
  • Paarakh, P. M. (2010). Nigella sativa Linn. – A comprehensive review. Indian Journal of Natural Products and Resources, 1, 409-429.
  • Paramore, L. C., Halpern M. T., Lapuerta, P., Hurley J. S., Frost ,F. J., Fairchild, D. G., & Bates, D. (2001). Impact of poorly controlled hypertension on healthcare resource utilization and cost. American Journal of Managed Care, 7(4), 389-401.
  • Parolin, P., Scotta M. I., & Bresch, C. (2014). Biology of Dittrichia viscosa, a Mediterranean ruderal plant: a review. Phyton, International Journal of Experimental Botany, 83, 251-262.
  • Pavela, R., Maggi, F., Lupidi, G., Mbuntcha H., Woguem V., Womeni, H. M., Barboni, L., Tapondjou, L. A., & Benelli G. (2018). Clausena anisata and Dysphania ambrosioides essential oils: from ethno-medicine to modern uses as effective insecticides. Environmental Science and Pollution Research, 25(11), 10493-10503.
  • Perelman, B., & Kuttin, E. (1988). Parsley‐induced photosensitivity in ostriches and ducks. Avian Pathology, 17(1), 183-192.
  • Perrinjaquet‐Moccetti, T., Busjahn, A., Schmidlin, C., Schmidt A., Bradl, B., & Aydogan, C. (2008). Food supplementation with an olive (Olea europaea L.) leaf extract reduces blood pressure in borderline hypertensive monozygotic twins. Phytotherapy Research, 22(9), 1239-1242.
  • Poorolajal, J., Hooshmand, E., Bahrami M., & Ameri P. (2016). How much excess weight loss can reduce the risk of hypertension? Journal of Public Health, 39(3), 95-102.
  • Prasanth Reddy, V., Ravi Vital, K., Varsha, P., & Satyam, S. (2014). Review on Thymus vulgaris traditional uses and pharmacological properties. Medicinal and Aromatic Plants, 3(3), 1000164.
  • Pulikottil, S., & Nath S. (2015). Potential of clove of Syzygium aromaticum in development of a therapeutic agent for periodontal disease: A review. South African Dental Journal, 70(3), 108-115.
  • Pulpati, H., Biradar Y. S., & Rajani M. (2008). High-performance thin-layer chromatography densitometric method for the quantification of harmine, harmaline, vasicine, and vasicinone in Peganum harmala. Journal of AOAC International, 91(5), 1179-1185.
  • Purushothaman, B., Prasanna Srinivasan, R., Suganthi P., Ranganathan, B., Gimbun, J., & Shanmugam, K. (2018). A comprehensive review on Ocimum basilicum. Journal of Natural Remedies, 18(3), 71-85.
  • Qayyum, R., Qamar, H. M.-u.-D., Khan, S., Salma, U., Khan, T., & Shah, A. J. (2016). Mechanisms underlying the antihypertensive properties of Urtica dioica. Journal of Translational Medicine, 14(1), 254.
  • Rhiouani, H., El-Hilaly J., Israili Z. H., & Lyoussi B. (2008). Acute and sub-chronic toxicity of an aqueous extract of the leaves of Herniaria glabra in rodents. Journal of Ethnopharmacology, 118(3), 378-386.
  • Rhiouani, H., Settaf, A., Lyoussi, B., Cherrah, Y., Lacaille-Dubois, M., & Hassar, M. (1999). Effects of saponins from Herniaria glabra on blood pressure and renal function in spontaneously hypertensive rats. Therapie, 54(6), 735-739.
  • Riaz, G., & Chopra, R. (2018). A review on phytochemistry and therapeutic uses of Hibiscus sabdariffa L. Biomedicine & Pharmacotherapy, 12, 575-586.
  • Rizwan, B. (2021). Therapeutic potential of Thymus vulgaris: A Review. The Annals of Research, 3, 147-161.
  • Said, A., Otmani, I., Derfoufi, S., & Benmoussa, A. (2015). Highlights on nutritional and therapeutic value of stinging nettle (Urtica dioica). International Journal of Pharmacy and Pharmaceutical Sciences, 7(10), 8-14.
  • Sakai, Y., Murakami T., & Yamamoto, Y. (2003). Antihypertensive effects of onion on NO synthase inhibitor-induced hypertensive rats and spontaneously hypertensive rats. Bioscience, Biotechnology, And Biochemistry, 67(6), 1305-1311.
  • Sayed, H., El-Latif H., Eid N., Elsayed, A., & El-Kader, E. (2009). Potential antihypertensive and antioxidative effects of Nigella sativa seeds or biomass and Syzygium aromaticum extracts on L-NAME-induced hypertensive rats. Egyptian Journal of Pharmaceutical Sciences, 50, 127-146.
  • Shahrajabian, M. H., Sun, W., & Cheng, Q. (2020). Chemical components and pharmacological benefits of Basil (Ocimum Basilicum): a review. International Journal of Food Properties, 23(1), 1961-1970.
  • Sharma, N., Ahirwar, D., Jhade, D., & Gupta, S. (2009). Medicinal and phamacological potential of nigella sativa: a review. Ethnobotanical Leaflets, 7, 11.
  • Sharma, S., & Agarwal, N. (2011). Nourishing and healing prowess of garden cress (Lepidium sativum Linn.)-A review. Indian Journal of Natural Products and Resources, 2, 292-297.
  • Singh, R. P., Gangadharappa, H., & Mruthunjaya K. (2017). Cuminum cyminum–A popular spice: An updated review. Pharmacognosy Journal, 9, 3.
  • Sivak, K., & Kaukhova, I. (2021). Evaluation of the diuretic effect of crude ethanol and saponin-rich extracts of Herniaria glabra L. in rats. Journal of Ethnopharmacology, 273113942.
  • Tabeshpour, J., Imenshahidi M., & Hosseinzadeh H. (2017). A review of the effects of Berberis vulgaris and its major component, berberine, in metabolic syndrome. Iranian Journal of Basic Medical Sciences, 20(5), 557.
  • Tahraoui, A., El-Hilaly J., Israili Z., & Lyoussi B. (2007). Ethnopharmacological survey of plants used in the traditional treatment of hypertension and diabetes in south-eastern Morocco (Errachidia province). Journal of Ethnopharmacology, 110(1), 105-117.
  • Teshika, J. D., Zakariyyah, A. M., Zaynab, T., Zengin, G., Rengasamy K. R., Pandian, S. K., & Fawzi ,M. M. (2019). Traditional and modern uses of onion bulb (Allium cepa L.): a systematic review. Critical Reviews in Food Science and Nutrition, 59(sup1), 39-70.
  • Ulbricht, C., Basch E., Burke D., Cheung L., Ernst E., Giese, N., Foppa, I., Hammerness, P., Hashmi, S., & Kuo G. (2008). Fenugreek (Trigonella foenum-graecum L. Leguminosae): an evidence-based systematic review by the natural standard research collaboration. Journal of Herbal Pharmacotherapy, 7(3-4), 143-177.
  • Umar, A., Imam G., Yimin W., Kerim P., Tohti I., Berké B., & Moore N. (2010). Antihypertensive effects of Ocimum basilicum L.(OBL) on blood pressure in renovascular hypertensive rats. Hypertension research, 33(7), 727.
  • Upadhyay, R. K. (2016). Nutraceutical, pharmaceutical and therapeutic uses of Allium cepa: A review. International Journal of Green Pharmacy (IJGP), 10, 1.
  • Valderrama, A.L., Gillespie, C., Mercado, C., (2013). Racial/Ethnic disparities in the awareness, treatment, and control of hypertension-United States, 2003-2010. Morbidity and Mortality Weekly Report, 62(18), 351-355.
  • Villar, A., Sanz, M., & Paya M. (1987). Hypotensive effect of Pistacia lentiscus L. International Journal of Crude Drug Research, 25(1), 1-3.
  • Williams, M., & Binns, W. (1968). Experimental photosensitization by spring parsley (Cymopterus watsonii) in chicks. American Journal of Veterinary Research, 29, 111-115.
  • Yadav, U. C., & Baquer, N. Z. (2014). Pharmacological effects of Trigonella foenum-graecum L. in health and disease. Pharmaceutical Biology, 52(2), 243-254.
  • Zaki M. (2020). Natural products from Dittrichia Viscosa (Mini-Review). RHAZES: Green and Applied Chemistry, 930-46.
  • Zeggwagh, N., Farid O., Michel J., & Eddouks, M. (2008). Cardiovascular effect of Artemisia herba alba aqueous extract in spontaneously hypertensive rats. Methods and Findings in Experimental and Clinical Pharmacology, 30(5), 375-381.
  • Zeggwagh, N. A., Moufid, A., Michel, J. B., & Eddouks, M. (2009). Hypotensive effect of Chamaemelum nobile aqueous extract in spontaneously hypertensive rats. Clinical and Experimental Hypertension, 31(5), 440-450.
  • Ziyyat, A., & Boussairi, E. H. (1998). Cardiovascular effects of Arbutus unedo L. in spontaneously hypertensive rats. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 12(2), 110-113.
  • Ziyyat, A., Legssyer, A., Mekhfi, H., Dassouli, A., Serhrouchni, M., & Benjelloun, W. (1997). Phytotherapy of hypertension and diabetes in oriental Morocco. Journal of Ethnopharmacology, 58(1), 45-54.
  • Zohra, T., Ovais, M., Khalil, A. T., Qasim, M., Ayaz, M., & Shinwari, Z. K. (2019). Extraction optimization, total phenolic, flavonoid contents, HPLC-DAD analysis and diverse pharmacological evaluations of Dysphania ambrosioides (L.) Mosyakin & Clemants. Natural Product Research, 33(1), 136-142.
Year 2022, Volume: 6 Issue: 1, 48 - 78, 01.06.2022
https://doi.org/10.47947/ijnls.1010197

Abstract

References

  • Abushouk, A. I., Salem, A. M. A., & Abdel-Daim, M. M. (2017). Berberis vulgaris for cardiovascular disorders: a scoping literature review. Iranian Journal of Oasic Medical Sciences, 20(5), 503- 510.
  • Agarwal, U., Pathak, D. P., Kapoor, G., Bhutani, R., Roper, R., Gupta, V., & Kant R. (2017). Review on Cuminum Cyminum—nature’s magical seeds. Journal of Chemical and Pharmaceutical Research, 9(9), 180-187.
  • Agyare, C., T. Appiah, Y.D. Boakye, & J. Apenteng, 2017. Petroselinum crispum: A Review. In: Medicinal Spices and Vegetables from Africa: Therapeutic Potential against Metabolic, Inflammatory, Infectious and Systemic Diseases, Kuete, V. (Ed.). Chapter 25, Elsevier, New York, USA., pp: 527-547.
  • Ahmad, A., Husain, A., Mujeeb, M., Khan, S. A., Najmi, A. K., Siddique, N. A., Damanhouri, Z. A., & Anwar, F. (2013). A review on therapeutic potential of Nigella sativa: A miracle herb. Asian Pacific Journal of Tropical Biomedicine, 3(5), 337-352.
  • Ahmad, S., Mir N., & Sultan, S. (2018). White-berry mistletoe (Viscum album L.): a hemiparasitic plant: occurrence and ethnobotanical use in Kashmir. Journal of Pharmacognosy and Phytochemistry, 7(1), 1831-1833.
  • Al-Qattan, K., Alnaqeeb, M., & Ali, M. (1999). The antihypertensive effect of garlic (Allium sativum) in the rat two-kidney–one-clip Goldblatt model. Journal of Ethnopharmacology, 66(2), 217-222.
  • Al-Snafi, A. E. (2016a). Medical importance of Anthemis nobilis (Chamaemelum nobile)-a review. Asian Journal of Pharmaceutical Science & Technology, 6(2), 89-95.
  • Al-Snafi, A. E. (2016b). The pharmacological activities of Cuminum cyminum-A review. IOSR Journal of Pharmacy, 6(6), 46-65.
  • Alam, K., Hoq, O., & Uddin, S. (2016). Medicinal plant Allium sativum. A review. Journal of Medicinal Plants Studies, 4(6), 72-79.
  • Ali, B. H., Wabel, N. A., & Blunden, G. (2005). Phytochemical, pharmacological and toxicological aspects of Hibiscus sabdariffa L.: a review. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 19(5), 369-375.
  • Allaq, A. A., Sidik, N. J., Abdul-Aziz, A., & Ahmed, I. A. (2020). Cumin (Cuminum cyminum L.): A review of its ethnopharmacology, phytochemistry. Biomedical Research and Therapy, 7(9), 4016-4021.
  • Amer, B., Juvik, O. J., Dupont, F., Francis, G. W., & Fossen, T. (2012). Novel aminoalkaloids from European mistletoe (Viscum album L.). Phytochemistry Letters, 5(3), 677-681.
  • Araniti, F., Lupini, A., Sunseri, F., & Abenavoli, M. R. (2017). Allelopatic potential of Dittrichia viscosa (L.) W. Greuter mediated by VOCs: A physiological and metabolomic approach. Plos One, 12(1), e0170161.
  • Arroyo, A. I., Pueyo, Y., Pellissier, F., Ramos, J., Espinosa-Ruiz, A., Millery, A., & Alados, C. L. (2018). Phytotoxic effects of volatile and water soluble chemicals of Artemisia herba-alba. Journal of Arid Environments, 151, 1-8.
  • Asdadi, A., Hamdouch, A., Gharby, S., & Hassani, L. M. I. (2020). Chemical characterization of essential oil of Artemisia herba-alba asso and his possible potential against covid-19. Journal of Analytical Sciences and Applied Biotechnology, 2(2), 2067-2072.
  • Assaidi, A., Legssyer, A., Berrichi, A., Aziz M., Mekhfi, H., Bnouham, M., & Ziyyat A. (2014). Hypotensive property of Chenopodium ambrosioides in anesthetized normotensive rats. Journal of Complementary and Integrative Medicine, 11(1), 1-7.
  • Awaad, A. A., El‐Meligy, R. M., Zain, G. M., Safhi, A. A., AL Qurain, N. A., Almoqren, S. S., Zain, Y. M., Sesh Adri, V. D., & Al‐Saikhan, F. I. (2018). Experimental and clinical antihypertensive activity of Matricaria chamomilla extracts and their angiotensin‐converting enzyme inhibitory activity. Phytotherapy Research, 32(8), 1564-1573.
  • Bahadır, Ş., Kadioğlu, İ., & Onaran, A. (2017). Antifungal activity of parasitic plant (Orobanche ramosa L. Cuscuta campestris Yunck. and Viscum album L.) extracts against some plant pathogenic fungi. Türkiye Herboloji Dergisi, 20(1), 61-69.
  • Baharvand-Ahmadi, B., & Asadi-Samani, M. (2017). A mini-review on the most important effective medicinal plants to treat hypertension in ethnobotanical evidence of Iran. Journal of Nephropharmacology, 6(1), 3-8.
  • Baharvand-Ahmadi, B., Bahmani, M., Tajeddini, P., Rafieian-Kopaei, M., & Naghdi, N. (2016). An ethnobotanical study of medicinal plants administered for the treatment of hypertension. Journal of Renal Injury Prevention, 5(3), 123-128.
  • Balaraman, R., Dangwal, S., & Mohan, M. (2006). Antihypertensive effect of trigonella foenum-greacum. seeds in experimentally induced hypertension in rats. Pharmaceutical Biology, 44(8), 568-575.
  • Benbott, A., Bahri, L., Boubendir, A., & Yahia, A. (2013). Study of the chemical components of Peganum harmala and evaluation of acute toxicity of alkaloids extracted in the Wistar albino mice. Journal of Material and Environmental Science, 4, 558-565.
  • Bento, I., & Pereira, J. A. (2011). Arbutus unedo L. and its benefits on human health. J Food Nutr Res, 5073-85.
  • Bertella, A., Benlahcen, K., Abouamama, S., Pinto, D. C., Maamar, K., Kihal, M., & Silva, A. M. (2018). Artemisia herba-alba Asso. essential oil antibacterial activity and acute toxicity. Industrial Crops and Products, 116, 137-143.
  • Bezerra, J. W. A., Costa, A. R., de Freitas, M. A., Rodrigues, F. C., de Souza, M. A., da Silva, A. R. P., Dos Santos, A. T. L., Linhares, K. V., Coutinho, H. D. M., & de Lima, Silva J. R. (2019). Chemical composition, antimicrobial, modulator and antioxidant activity of essential oil of Dysphania ambrosioides (L.) Mosyakin & Clemants. Comparative Immunology, Microbiology and Infectious Diseases, 65, 58-64.
  • Bilal, A., Jahan, N., Ahmed, A., Bilal, S. N., Habib, S., & Hajra, S. (2012). Phytochemical and pharmacological studies on Ocimum basilicum Linn-A review. International Journal of Current Research and Review, 4(23), 73-83.
  • Boutkhil, S., El Idrissi, M., Amechrouq, A., Chbicheb, A., Chakir, S., & El Badaoui, K. (2009). Chemical composition and antimicrobial activity of crude, aqueous, ethanol extracts and essential oils of Dysphania ambrosioides (L.) Mosyakin & Clemants. Acta Botanica Gallica, 156(2), 201-209.
  • Bouzidi, A., Mahdeb, N., & Kara, N. (2011). Toxicity studies of alkaloids of seeds of Datura stramonium and synthesis alkaloids in male rats. Journal of Medicinal Plants Research, 5(15), 3421-3431.
  • Bystrická, J., Musilová, J., Vollmannová, A., Timoracká, M., & Kavalcová, P. (2013). Bioactive components of onion (Allium cepa L.) - A Review. Acta Alimentaria, 42(1), 11-22.
  • Camejo-Rodrigues, J., Ascensao, L., Bonet, M. À., & Valles, J. (2003). An ethnobotanical study of medicinal and aromatic plants in the Natural Park of “Serra de São Mamede” (Portugal). Journal of Ethnopharmacology, 89(2-3), 199-209.
  • Cavero, R., Akerreta, S., & Calvo, M. (2011a). Pharmaceutical ethnobotany in Northern Navarra (Iberian Peninsula). Journal of Ethnopharmacology, 133(1), 138-146.
  • Cavero, R., Akerreta, S., & Calvo, M. (2011b). Pharmaceutical ethnobotany in the middle Navarra (Iberian Peninsula). Journal of Ethnopharmacology, 137(1), 844-855.
  • Charef, M., Yousfi, M., Saidi, M., & Stocker, P. (2008). Determination of the fatty acid composition of acorn (Quercus), Pistacia lentiscus seeds growing in Algeria. Journal of the American Oil Chemists' Society, 85(10), 921-924.
  • Cortés-Rojas, D. F., de Souza C. R. F., & Oliveira W. P. (2014). Clove (Syzygium aromaticum): a precious spice. Asian Pacific Journal of Tropical Biomedicine, 4(2), 90-96.
  • Da-Costa-Rocha, I., Bonnlaender, B., Sievers, H., Pischel, I., & Heinrich, M. (2014). Hibiscus sabdariffa L.–A phytochemical and pharmacological review. Food Chemistry, 165, 424-443.
  • De Wet, H., Ramulondi, M., & Ngcobo, Z. (2016). The use of indigenous medicine for the treatment of hypertension by a rural community in northern Maputaland, South Africa. South African Journal of Botany, 103, 78-88.
  • Dehkordi, F. R., & Kamkhah, A. F. (2008). Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension. Fundamental & Clinical Pharmacology, 22(4), 447-452.
  • Dias-Martins A. M., Pessanha K. L. F., Pacheco S., Rodrigues J. A. S., & Carvalho C. W. P. (2018). Potential use of pearl millet (Pennisetum glaucum (L.) R. Br.) in Brazil: Food security, processing, health benefits and nutritional products. Food Research International, 109, 175-186.
  • Douira, A., & Zidane, L. (2015). Étude ethnobotanique des plantes médicinales utilisées dans le traitement du diabète, et des maladies cardiaques dans la région d’Izarène (Nord du Maroc). Journal of Applied Biosciences, 86(1), 7940–7956.
  • Eddouks, M., Maghrani, M., Lemhadri, A., Ouahidi, M.-L., & Jouad, H. (2002). Ethnopharmacological survey of medicinal plants used for the treatment of diabetes mellitus, hypertension and cardiac diseases in the south-east region of Morocco (Tafilalet). Journal of Ethnopharmacology, 82(2-3), 97-103.
  • El-Saber Batiha, G., Magdy Beshbishy, A., G Wasef L., Elewa Y. H., A Al-Sagan A., El-Hack A., Mohamed E., Taha, A. E., M Abd-Elhakim Y., & Prasad Devkota, H. (2020). Chemical constituents and pharmacological activities of garlic (Allium sativum L.): A review. Nutrients, 12(3), 872. https://doi.org/10.3390/nu12030872
  • Falana H., Nofal W., & Nakhleh H. (2014). A review article Lepidium sativum (Garden cress). In: Pharm-D Program, College of Nursing, Pharmacy and Health Professions, Birzeit University, Birzeit, Palestine, 1-8.
  • Fatehi‐Hassanabad, Z., Jafarzadeh, M., Tarhini, A., & Fatehi, M. (2005). The antihypertensive and vasodilator effects of aqueous extract from Berberis vulgaris fruit on hypertensive rats. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 19(3), 222-225.
  • Gaire, B. P., & Subedi, L. (2013). A review on the pharmacological and toxicological aspects of Datura stramonium L. Journal of Integrative Medicine, 11(2), 73-79.
  • Galavi, A., Hosseinzadeh, H., & Razavi, B. M. (2021). The effects of Allium cepa L. (onion) and its active constituents on metabolic syndrome: A review. Iranian Journal of Basic Medical Sciences, 24(1), 3-16. https://doi.org/10.22038/ijbms.2020.46956.10843.
  • Gbekley, H. E., Karou, S. D., Katawa, G., Tchacondo, T., Batawila, K., Ameyapoh, Y., & Simpore, J. (2018). Ethnobotanical survey of medicinal plants used in the management of hypertension in the maritime region of Togo. African Journal of Traditional, Complementary and Alternative Medicines, 15(1), 85-97.
  • Ghanbari, R., Anwar, F., Alkharfy, K. M., Gilani, A.-H., & Saari, N. (2012). Valuable nutrients and functional bioactives in different parts of olive (Olea europaea L.)—a review. International Journal of Molecular Sciences, 13(3), 3291-3340.
  • Grauso, L., Cesarano, G., Zotti M., Ranesi, M., Sun, W., Bonanomi, G., & Lanzotti, V. (2019). Exploring Dittrichia viscosa (L.) Greuter phytochemical diversity to explain its antimicrobial, nematicidal and insecticidal activity. Phytochemistry Reviews, 19, 659-689.
  • Gupta, V., Mittal, P., Bansal, P., Khokra, S. L., & Kaushik, D. (2010). Pharmacological potential of Matricaria recutita-A review. International Journal of Pharmaceutical Sciences and Drug Research, 2(1), 12-16.
  • Hakkou, Z., Maciuk, A., Leblais, V., Bouanani, N. E., Mekhfi, H., Bnouham, M., Aziz, M., Ziyyat, A., Rauf, A., & Hadda, T. B. (2017). Antihypertensive and vasodilator effects of methanolic extract of Inula viscosa: Biological evaluation and POM analysis of cynarin, chlorogenic acid as potential hypertensive. Biomedicine & Pharmacotherapy, 93, 62-69.
  • Hameed, I. H., Mohammed, G. J., & Kamal, S. A. (2018). A review: Uses and Pharmacological activity of Matricaria chamomilla. Indian Journal of Public Health Research and Development, 9(3), 200-205.
  • Horner, O., Cheap-Charpentier, H., Cachet, X., Perrot, H., Lédion, J., Gelus, D., Pécoul, N., Litaudon, M., & Roussi, F. (2017). Antiscalant properties of Herniaria glabra aqueous solution. Desalination, 409, 157-162.
  • Hosseinzadeh, S., Jafarikukhdan, A., Hosseini, A., & Armand, R. (2015). The application of medicinal plants in traditional and modern medicine: a review of Thymus vulgaris. International Journal of Clinical Medicine, 6(9), 635-642.
  • Hussein, H. J., Hameed, I. H., & Hadi, M. Y. (2017). A Review: Anti-microbial, Anti-inflammatory effect and Cardiovascular effects of Garlic: Allium sativum. Research Journal of Pharmacy and Technology, 10(11), 4069-4078.
  • Idm’hand, H., Msanda, F., & Cherifi, K. (2019). Ethnopharmacological Documentation of Medicinal Plants Used in the Traditional Treatment of Hypertension in Tarfaya Province, Morocco. International Journal of Pharmacology, Phytochemistry and Ethnomedicine, 14, 16-39.
  • Imanshahidi, M., & Hosseinzadeh, H. (2008). Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytotherapy Research, 22(8), 999-1012.
  • Imenshahidi, M., & Hosseinzadeh, H. (2016). Berberis vulgaris and berberine: an update review. Phytotherapy Research, 30(11), 1745-1764.
  • Joshi, B. C., Mukhija, M., & Kalia, A. N. (2014). Pharmacognostical review of Urtica dioica L. International Journal of Green Pharmacy, 8(4), 201-209.
  • Jouad, H., Haloui, M., Rhiouani, H., El Hilaly, J., & Eddouks, M. (2001). Ethnobotanical survey of medicinal plants used for the treatment of diabetes, cardiac and renal diseases in the North centre region of Morocco (Fez–Boulemane). Journal of Ethnopharmacology, 77(2-3), 175-182.
  • Kalaivani, P., Saranya, R. B., Ramakrishnan, G., Ranju, V., Sathiya, S., Gayathri, V., Thiyagarajan, L. K., Venkhatesh, J. R., Babu, C. S., & Thanikachalam, S. (2013). Cuminum cyminum, a dietary spice, attenuates hypertension via endothelial nitric oxide synthase and NO pathway in renovascular hypertensive rats. Clinical and Experimental Hypertension, 35(7), 534-542.
  • Kang, S.-J., & Chung, S.-K. (2012). Antioxidant and antimicrobial activities of Korean mistletoe (Viscum album var. coloratum) extracts against food poisoning bacteria. Korean Journal of Food Preservation, 19(6), 919-924.
  • Karou, S. D., Tchacondo, T., Djikpo Tchibozo M. A., Abdoul-Rahaman, S., Anani, K., Koudouvo, K., Batawila, K., Agbonon, A., Simpore, J., & de Souza, C. (2011). Ethnobotanical study of medicinal plants used in the management of diabetes mellitus and hypertension in the Central Region of Togo. Pharmaceutical Biology, 49(12), 1286-1297.
  • Kaur, K., & Kaushal, S. (2019). Phytochemistry and pharmacological aspects of Syzygium aromaticum: A review. J Pharmacogn Phytochem, 8, 398-406.
  • Kazemian, H., Ghafourian, S., Heidari, H., Amiri, P., Yamchi, J. K., Shavalipour, A., Houri, H., Maleki, A., & Sadeghifard N. (2015). Antibacterial, anti-swarming and anti-biofilm formation activities of Chamaemelum nobile against Pseudomonas aeruginosa. Revista da Sociedade Brasileira de Medicina Tropical, 48(4), 432-436.
  • Kazemian, H., Ghafourian, S., Sadeghifard, N., Houshmandfar, R., Badakhsh, B., Taji, A., Shavalipour, A., Mohebi, R., Ebrahim-Saraie, H. S., & Houri, H. (2018). In vivo antibacterial and wound healing activities of Roman chamomile (Chamaemelum nobile). Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious Disorders), 18(1), 41-45.
  • Kensara, O. A., ElSawy, N. A., El-Shemi, A. G., & Header, E. A. (2013). Thymus vulgaris supplementation attenuates blood pressure and aorta damage in hypertensive rats. Journal of Medicinal Plants Research, 7(11), 669-676.
  • Khan, T., Ali S., Qayyum, R., Hussain, I., Wahid, F., & Shah, A. J. (2016). Intestinal and vascular smooth muscle relaxant effect of Viscum album explains its medicinal use in hyperactive gut disorders and hypertension. BMC Complementary and Alternative Medicine, 16(1), 1-8.
  • Khan, Y., Panchal, S., Vyas, N., Butani, A., & Kumar, V. (2007). Olea europaea: a phyto-pharmacological review. Pharmacognosy Reviews, 1(1), 114-118.
  • Kienle, G. S., & Kiene, H. (2010). Influence of Viscum album L (European mistletoe) extracts on quality of life in cancer patients: a systematic review of controlled clinical studies. Integrative Cancer Therapies, 9(2), 142-157. Kovarovič, J., Bystricka, J., Vollmannova, A., Toth, T., & Brindza, J. (2019). Biologically valuable substances in garlic (Allium sativum L.)–A review. Journal of Central European Agriculture, 20(1), 292-304.
  • Kozachok, S., Marchyshyn, S., Ostapchuk, A., & Zavyalova, L. (2016). Monosaccharide composition of Herniaria glabra L. and Herniaria polygama J. Gay. Current Issues in Pharmacy and Medical Sciences, 29(3), 142-144.
  • Kozachok, S., Pecio, Ł., Kolodziejczyk-Czepas, J., Marchyshyn, S., Nowak, P., Mołdoch, J., & Oleszek, W. (2018). γ-Pyrone compounds: flavonoids and maltol glucoside derivatives from Herniaria glabra L. collected in the Ternopil region of the Ukraine. Phytochemistry, 152, 213-222.
  • Kozachok, S., Pecio, Ł., Orhan, I. E., Deniz, F. S. S., Marchyshyn, S., & Oleszek, W. (2020). Reinvestigation of Herniaria glabra L. saponins and their biological activity. Phytochemistry, 169, 112162.
  • Leung, A. A., Daskalopoulou, S. S., Dasgupta, K., McBrien, K., Butalia, S., Zarnke, K. B., Nerenberg, K., Harris, K. C., Nakhla M., & Cloutier L. (2017). Hypertension Canada's 2017 guidelines for diagnosis, risk assessment, prevention, and treatment of hypertension in adults. Canadian Journal of Cardiology, 33(5), 557-576.
  • Liu, X., Wang, X., Chen, Z., Ye, J., Liao, Y., Zhang, W., Chang, J., & Xu, F. (2019). De novo assembly and comparative transcriptome analysis: novel insights into terpenoid biosynthesis in Chamaemelum nobile L. Plant Cell Reports, 38(1), 101-116.
  • Ljubuncic, P., Song, H., Cogan, U., Azaizeh, H., & Bomzon, A. (2005). The effects of aqueous extracts prepared from the leaves of Pistacia lentiscus in experimental liver disease. Journal of Ethnopharmacology, 100(1-2), 198-204.
  • Lyu, S.-Y., Rhim, J.-Y., Moon, Y.-S., Jung, S.-H., Lee, K.-Y., & Park, W.-B. (2002). Antitumor activities of extract of Viscum album var. coloratum Modified with Viscum album var. coloratum Agglutinin. Natural Product Sciences, 8(4), 155-161.
  • Maghrani, M., Zeggwagh, N.-A., Michel, J.-B., & Eddouks, M. (2005). Antihypertensive effect of Lepidium sativum L. in spontaneously hypertensive rats. Journal of Ethnopharmacology, 100(1-2), 193-197.
  • Mali, R. G., Mahajan, S. G., & Mehta, A. A. (2007). Lepidium sativum (Garden cress): a review of contemporary literature and medicinal properties. Oriental Pharmacy and Experimental Medicine, 7(4), 331-335.
  • Manohar, D., Viswanatha, G., Nagesh, S., Jain, V., & Shivaprasad, H. (2012). Ethnopharmacology of Lepidium sativum Linn (Brassicaceae): a review. International Journal of Phytothearpy Research, 2(1), 1-7.
  • Mansley, M. K., Ivy, J. R., & Bailey, M. A. (2016). The Evolution of Hypertension–Old Genes, New Concepts. Kidney International Reports, ISN Forefronts Symposium 2015, 1(3), 197-203.
  • Mehenni, C., Atmani-Kilani, D., Dumarçay, S., Perrin, D., Gérardin, P., & Atmani, D. (2016). Hepatoprotective and antidiabetic effects of Pistacia lentiscus leaf and fruit extracts. journal of Food and Drug Analysis, 24(3), 653-669.
  • Mezni, F., Shili, S., Ben Ali N., Larbi Khouja, M., Khaldi, A., & Maaroufi, A. (2016). Evaluation of Pistacia lentiscus seed oil and phenolic compounds for in vitro antiproliferative effects against BHK21 cells. Pharmaceutical biology, 54(5), 747-751.
  • Miguel, M. G., Faleiro M. L., Guerreiro A. C., & Antunes M. D. (2014). Arbutus unedo L.: chemical and biological properties. Molecules, 19(10), 15799-15823.
  • Miraj, S., & Alesaeidi, S. (2016). A systematic review study of therapeutic effects of Matricaria recuitta chamomile (chamomile). Electronic Physician, 8(9), 3024-3031.
  • Miraj, S., & Kiani, S. (2016). Study of pharmacological effect of Ocimum basilicum: A review. Der Pharmacia Lettre, 8(9), 276-280.
  • Mittal, M., Gupta, N., Parashar, P., Mehra, V., & Khatri, M. (2014). Phytochemical evaluation and pharmacological activity of Syzygium aromaticum: a comprehensive review. International Journal of Pharmacy and Pharmaceutical Sciences, 6(8), 67-72.
  • Mnif, S., & Aifa, S. (2015). Cumin (Cuminum cyminum L.) from traditional uses to potential biomedical applications. Chemistry & Biodiversity, 12(5), 733-742.
  • Mohamed, A. E.-H. H., El-Sayed, M., Hegazy, M. E., Helaly, S. E., Esmail, A. M., & Mohamed, N. S. (2010). Chemical constituents and biological activities of Artemisia herba-alba. Records of Natural Products, 4(1), 1-25.
  • Mohammed, M. J., Anand, U., Altemimi, A. B., Tripathi, V., Guo, Y., & Pratap-Singh, A. (2021). Phenolic Composition, Antioxidant Capacity and Antibacterial Activity of White Wormwood (Artemisia herba-alba). Plants, 10(1), 164. https://doi.org/10.3390/plants10010164
  • Mohebbati, R., & Abbasnezhad, A. (2020). Effects of Nigella sativa on endothelial dysfunction in diabetes mellitus: A review. Journal of ethnopharmacology, 252, 112585. https://doi.org/10.1016/j.jep.2020.112585
  • Mohsen, H., & Ali, F. (2009). Essential oil composition of Artemisia herba-alba from southern Tunisia. Molecules, 14(4), 1585-1594.
  • Mojiminiyi, F., Dikko, M., Muhammad, B., Ojobor, P., Ajagbonna, O., Okolo, R., Igbokwe, U., Mojiminiyi, U., Fagbemi, M., & Bello, S. (2007). Antihypertensive effect of an aqueous extract of the calyx of Hibiscus sabdariffa. Fitoterapia, 78(4), 292-297.
  • Morales-González, J. A., Madrigal-Bujaidar, E., Sánchez-Gutiérrez, M., Izquierdo-Vega, J. A., Valadez-Vega, M. d. C., Álvarez-González, I., Morales-González, Á., & Madrigal-Santillán, E. (2019). Garlic (Allium sativum L.): A brief review of its antigenotoxic effects. Foods, 8(8), 343. https://doi.org/10.3390/foods8080343
  • Morgado S., Morgado, M., Plácido, A. I., Roque, F., & Duarte, A. P. (2018). Arbutus unedo L.: From traditional medicine to potential uses in modern pharmacotherapy. Journal of Ethnopharmacology, 225, 90-102.
  • Murti, K., Panchal, M. A., Gajera, V., & Solanki, J. (2012). Pharmacological properties of Matricaria recutita: a review. Pharmacologia, 3(8), 348-351.
  • Mushtaq, M. N., & Akhtar, M. S. (2015). Blood pressure lowering effect of Pennisetum glaucum in rats. Bangladesh Journal of Pharmacology, 10(3), 494-499.
  • Mwanauta, R. W., Mtei, K. A., & Ndakidemi, P. A. (2014). Prospective bioactive compounds from Vernonia amygdalina, Lippia javanica, Dysphania ambrosioides and Tithonia diversifolia in controlling legume insect pests. Agricultural Sciences, 5(12), 1129.
  • Nambiar, V. S., Dhaduk, J., Sareen N., Shahu T., & Desai, R. (2011). Potential functional implications of pearl millet (Pennisetum glaucum) in health and disease. Journal of Applied Pharmaceutical Science, 1(10), 62.
  • Nathiya, S., Durga, M., & Devasena, T. (2014). Therapeutic role of Trigonella foenum-graecum [fenugreek]–a review. International Journal of Pharmaceutical Sciences Review and Research, 27(2), 74-80.
  • Niazi, M., Yari, F., & Shakarami, A. (2019). A Review of Medicinal Herbs in the Lamiaceae Family Used to Treat Arterial Hypertension. Entomology and Applied Science Letters, 6(1), 22-37.
  • Ofem, O., Eno, A., Imoru J., Nkanu E., Unoh F., & Ibu J. (2007). Effect of crude aqueous leaf extract of Viscum album (mistletoe) in hypertensive rats. Indian Journal of Pharmacology, 39(1), 15-19.
  • Olaiya, C. O., & Soetan, K. O. (2014). A review of the health benefits of fenugreek (Trigonella foenum-graecum L.): Nutritional, Biochemical and pharmaceutical perspectives. A merican Journal of Social Issues and Humanities, 43, 12.
  • Osei, Akoto, C., Acheampong, A., Boakye, Y. D., Naazo, A. A., & Adomah, D. H. (2020). Anti-inflammatory, antioxidant, and anthelmintic activities of Ocimum basilicum (Sweet Basil) fruits. Journal of Chemistry, 2153534, https://doi.org/10.1155/2020/2153534
  • Özcan, M. M., & Matthäus, B. (2017). A review: benefit and bioactive properties of olive (Olea europaea L.) leaves. European Food Research and Technology, 243(1), 89-99.
  • Paarakh, P. M. (2010). Nigella sativa Linn. – A comprehensive review. Indian Journal of Natural Products and Resources, 1, 409-429.
  • Paramore, L. C., Halpern M. T., Lapuerta, P., Hurley J. S., Frost ,F. J., Fairchild, D. G., & Bates, D. (2001). Impact of poorly controlled hypertension on healthcare resource utilization and cost. American Journal of Managed Care, 7(4), 389-401.
  • Parolin, P., Scotta M. I., & Bresch, C. (2014). Biology of Dittrichia viscosa, a Mediterranean ruderal plant: a review. Phyton, International Journal of Experimental Botany, 83, 251-262.
  • Pavela, R., Maggi, F., Lupidi, G., Mbuntcha H., Woguem V., Womeni, H. M., Barboni, L., Tapondjou, L. A., & Benelli G. (2018). Clausena anisata and Dysphania ambrosioides essential oils: from ethno-medicine to modern uses as effective insecticides. Environmental Science and Pollution Research, 25(11), 10493-10503.
  • Perelman, B., & Kuttin, E. (1988). Parsley‐induced photosensitivity in ostriches and ducks. Avian Pathology, 17(1), 183-192.
  • Perrinjaquet‐Moccetti, T., Busjahn, A., Schmidlin, C., Schmidt A., Bradl, B., & Aydogan, C. (2008). Food supplementation with an olive (Olea europaea L.) leaf extract reduces blood pressure in borderline hypertensive monozygotic twins. Phytotherapy Research, 22(9), 1239-1242.
  • Poorolajal, J., Hooshmand, E., Bahrami M., & Ameri P. (2016). How much excess weight loss can reduce the risk of hypertension? Journal of Public Health, 39(3), 95-102.
  • Prasanth Reddy, V., Ravi Vital, K., Varsha, P., & Satyam, S. (2014). Review on Thymus vulgaris traditional uses and pharmacological properties. Medicinal and Aromatic Plants, 3(3), 1000164.
  • Pulikottil, S., & Nath S. (2015). Potential of clove of Syzygium aromaticum in development of a therapeutic agent for periodontal disease: A review. South African Dental Journal, 70(3), 108-115.
  • Pulpati, H., Biradar Y. S., & Rajani M. (2008). High-performance thin-layer chromatography densitometric method for the quantification of harmine, harmaline, vasicine, and vasicinone in Peganum harmala. Journal of AOAC International, 91(5), 1179-1185.
  • Purushothaman, B., Prasanna Srinivasan, R., Suganthi P., Ranganathan, B., Gimbun, J., & Shanmugam, K. (2018). A comprehensive review on Ocimum basilicum. Journal of Natural Remedies, 18(3), 71-85.
  • Qayyum, R., Qamar, H. M.-u.-D., Khan, S., Salma, U., Khan, T., & Shah, A. J. (2016). Mechanisms underlying the antihypertensive properties of Urtica dioica. Journal of Translational Medicine, 14(1), 254.
  • Rhiouani, H., El-Hilaly J., Israili Z. H., & Lyoussi B. (2008). Acute and sub-chronic toxicity of an aqueous extract of the leaves of Herniaria glabra in rodents. Journal of Ethnopharmacology, 118(3), 378-386.
  • Rhiouani, H., Settaf, A., Lyoussi, B., Cherrah, Y., Lacaille-Dubois, M., & Hassar, M. (1999). Effects of saponins from Herniaria glabra on blood pressure and renal function in spontaneously hypertensive rats. Therapie, 54(6), 735-739.
  • Riaz, G., & Chopra, R. (2018). A review on phytochemistry and therapeutic uses of Hibiscus sabdariffa L. Biomedicine & Pharmacotherapy, 12, 575-586.
  • Rizwan, B. (2021). Therapeutic potential of Thymus vulgaris: A Review. The Annals of Research, 3, 147-161.
  • Said, A., Otmani, I., Derfoufi, S., & Benmoussa, A. (2015). Highlights on nutritional and therapeutic value of stinging nettle (Urtica dioica). International Journal of Pharmacy and Pharmaceutical Sciences, 7(10), 8-14.
  • Sakai, Y., Murakami T., & Yamamoto, Y. (2003). Antihypertensive effects of onion on NO synthase inhibitor-induced hypertensive rats and spontaneously hypertensive rats. Bioscience, Biotechnology, And Biochemistry, 67(6), 1305-1311.
  • Sayed, H., El-Latif H., Eid N., Elsayed, A., & El-Kader, E. (2009). Potential antihypertensive and antioxidative effects of Nigella sativa seeds or biomass and Syzygium aromaticum extracts on L-NAME-induced hypertensive rats. Egyptian Journal of Pharmaceutical Sciences, 50, 127-146.
  • Shahrajabian, M. H., Sun, W., & Cheng, Q. (2020). Chemical components and pharmacological benefits of Basil (Ocimum Basilicum): a review. International Journal of Food Properties, 23(1), 1961-1970.
  • Sharma, N., Ahirwar, D., Jhade, D., & Gupta, S. (2009). Medicinal and phamacological potential of nigella sativa: a review. Ethnobotanical Leaflets, 7, 11.
  • Sharma, S., & Agarwal, N. (2011). Nourishing and healing prowess of garden cress (Lepidium sativum Linn.)-A review. Indian Journal of Natural Products and Resources, 2, 292-297.
  • Singh, R. P., Gangadharappa, H., & Mruthunjaya K. (2017). Cuminum cyminum–A popular spice: An updated review. Pharmacognosy Journal, 9, 3.
  • Sivak, K., & Kaukhova, I. (2021). Evaluation of the diuretic effect of crude ethanol and saponin-rich extracts of Herniaria glabra L. in rats. Journal of Ethnopharmacology, 273113942.
  • Tabeshpour, J., Imenshahidi M., & Hosseinzadeh H. (2017). A review of the effects of Berberis vulgaris and its major component, berberine, in metabolic syndrome. Iranian Journal of Basic Medical Sciences, 20(5), 557.
  • Tahraoui, A., El-Hilaly J., Israili Z., & Lyoussi B. (2007). Ethnopharmacological survey of plants used in the traditional treatment of hypertension and diabetes in south-eastern Morocco (Errachidia province). Journal of Ethnopharmacology, 110(1), 105-117.
  • Teshika, J. D., Zakariyyah, A. M., Zaynab, T., Zengin, G., Rengasamy K. R., Pandian, S. K., & Fawzi ,M. M. (2019). Traditional and modern uses of onion bulb (Allium cepa L.): a systematic review. Critical Reviews in Food Science and Nutrition, 59(sup1), 39-70.
  • Ulbricht, C., Basch E., Burke D., Cheung L., Ernst E., Giese, N., Foppa, I., Hammerness, P., Hashmi, S., & Kuo G. (2008). Fenugreek (Trigonella foenum-graecum L. Leguminosae): an evidence-based systematic review by the natural standard research collaboration. Journal of Herbal Pharmacotherapy, 7(3-4), 143-177.
  • Umar, A., Imam G., Yimin W., Kerim P., Tohti I., Berké B., & Moore N. (2010). Antihypertensive effects of Ocimum basilicum L.(OBL) on blood pressure in renovascular hypertensive rats. Hypertension research, 33(7), 727.
  • Upadhyay, R. K. (2016). Nutraceutical, pharmaceutical and therapeutic uses of Allium cepa: A review. International Journal of Green Pharmacy (IJGP), 10, 1.
  • Valderrama, A.L., Gillespie, C., Mercado, C., (2013). Racial/Ethnic disparities in the awareness, treatment, and control of hypertension-United States, 2003-2010. Morbidity and Mortality Weekly Report, 62(18), 351-355.
  • Villar, A., Sanz, M., & Paya M. (1987). Hypotensive effect of Pistacia lentiscus L. International Journal of Crude Drug Research, 25(1), 1-3.
  • Williams, M., & Binns, W. (1968). Experimental photosensitization by spring parsley (Cymopterus watsonii) in chicks. American Journal of Veterinary Research, 29, 111-115.
  • Yadav, U. C., & Baquer, N. Z. (2014). Pharmacological effects of Trigonella foenum-graecum L. in health and disease. Pharmaceutical Biology, 52(2), 243-254.
  • Zaki M. (2020). Natural products from Dittrichia Viscosa (Mini-Review). RHAZES: Green and Applied Chemistry, 930-46.
  • Zeggwagh, N., Farid O., Michel J., & Eddouks, M. (2008). Cardiovascular effect of Artemisia herba alba aqueous extract in spontaneously hypertensive rats. Methods and Findings in Experimental and Clinical Pharmacology, 30(5), 375-381.
  • Zeggwagh, N. A., Moufid, A., Michel, J. B., & Eddouks, M. (2009). Hypotensive effect of Chamaemelum nobile aqueous extract in spontaneously hypertensive rats. Clinical and Experimental Hypertension, 31(5), 440-450.
  • Ziyyat, A., & Boussairi, E. H. (1998). Cardiovascular effects of Arbutus unedo L. in spontaneously hypertensive rats. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 12(2), 110-113.
  • Ziyyat, A., Legssyer, A., Mekhfi, H., Dassouli, A., Serhrouchni, M., & Benjelloun, W. (1997). Phytotherapy of hypertension and diabetes in oriental Morocco. Journal of Ethnopharmacology, 58(1), 45-54.
  • Zohra, T., Ovais, M., Khalil, A. T., Qasim, M., Ayaz, M., & Shinwari, Z. K. (2019). Extraction optimization, total phenolic, flavonoid contents, HPLC-DAD analysis and diverse pharmacological evaluations of Dysphania ambrosioides (L.) Mosyakin & Clemants. Natural Product Research, 33(1), 136-142.
There are 144 citations in total.

Details

Primary Language English
Subjects Biochemistry and Cell Biology (Other)
Journal Section Review article
Authors

Elhassan Idm'hand 0000-0001-9548-6231

Fouad Msanda This is me 0000-0003-2769-7285

Khalil Cherifi This is me 0000-0003-2024-6967

Early Pub Date January 16, 2022
Publication Date June 1, 2022
Submission Date October 15, 2021
Acceptance Date January 2, 2022
Published in Issue Year 2022 Volume: 6 Issue: 1

Cite

APA Idm’hand, E., Msanda, F., & Cherifi, K. (2022). A review of Moroccan Medicinal Plants Used in the Treatment of Hypertension. International Journal of Nature and Life Sciences, 6(1), 48-78. https://doi.org/10.47947/ijnls.1010197