Case Report
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Year 2024, Volume: 8 Issue: 1, 61 - 66, 01.06.2024
https://doi.org/10.47947/ijnls.1487910

Abstract

References

  • Bacq, Y., Jacquemin, E., Balabaud, C., Jeannot, E., Scotto, B., Branchereau, S., Laurent, C., Bourlier, P., Pariente, D., de Muret, A., Fabre, M., Bioulac-Sage, P., & Zucman-Rossi, J. (2003). Familial liver adenomatosis associated with hepatocyte nuclear factor 1alpha inactivation. Gastroenterology, 125 (5), 1470-1475. https://doi.org/10.1016/j.gastro.2003.07.012
  • Bala, S., Wünsch, P. H., & Ballhausen, W. G. (1997). Childhood hepatocellular adenoma in familial adenomatous polyposis: mutations in adenomatous polyposis coli gene and p53. Gastroenterology, 112 (3), 919-922. https://doi.org/10.1053/gast.1997.v112.pm9041254
  • Baum, J. K., Bookstein, J. J., Holtz, F., & Klein, E. W. (1973). Possible association between benign hepatomas and oral contraceptives. Lancet (London, England), 2 (7835), 926-929. https://doi.org/10.1016/s0140-6736(73)92594-4
  • Bieze, M., Phoa, S. S., Verheij, J., van Lienden, K. P., & van Gulik, T. M. (2014). Risk factors for bleeding in hepatocellular adenoma. The British Journal of Surgery, 10 1(7), 847-855. https://doi.org/10.1002/bjs.9493
  • Bioulac-Sage, P., Sempoux, C., & Balabaud, C. (2017). Hepatocellular adenoma: Classification, variants and clinical relevance. Seminars in Diagnostic Pathology, 34 (2), 112-125. https://doi.org/10.1053/j.semdp.2016.12.007
  • Coombes, G. B., Reiser, J., Paradinas, F. J., & Burn, I. (1978). An androgen-associated hepatic adenoma in a trans-sexual. The British Journal of Surgery, 65 (12), 869-870. https://doi.org/10.1002/bjs.1800651212
  • Foster, J. H., & Berman, M. M. (1994). The malignant transformation of liver cell adenomas. Archives of Surgery (Chicago, Ill. : 1960), 129 (7), 712–717. https://doi.org/10.1001/archsurg.1994.01420310044007
  • Fujiyama, S., Sato, K., Sakai, M., Sato, T., Tashiro, S., & Arakawa, M. (1990). A case of type Ia glycogen storage disease complicated by hepatic adenoma. Hepato-Gastroenterology, 37 (4), 432-435.
  • Grazioli, L., Federle, M. P., Brancatelli, G., Ichikawa, T., Olivetti, L., & Blachar, A. (2001). Hepatic adenomas: imaging and pathologic findings. Radiographics: a review publication of the Radiological Society of North America, Inc, 21 (4), 877-894. https://doi.org/10.1148/radiographics.21.4.g01jl04877
  • Klatskin G. (1977). Hepatic tumors: possible relationship to use of oral contraceptives. Gastroenterology, 73 (2), 386-394.
  • Labrune, P., Trioche, P., Duvaltier, I., Chevalier, P., & Odièvre, M. (1997). Hepatocellular adenomas in glycogen storage disease type I and III: a series of 43 patients and review of the literature. Journal of Pediatric Gastroenterology and Nutrition, 24 (3), 276-279. https://doi.org/10.1097/00005176-199703000-00008
  • Nakao, A., Sakagami, K., Nakata, Y., Komazawa, K., Amimoto, T., Nakashima, K., Isozaki, H., Takakura, N., & Tanaka, N. (2000). Multiple hepatic adenomas caused by long-term administration of androgenic steroids for aplastic anemia in association with familial adenomatous polyposis. Journal of Gastroenterology, 35 (7), 557-562. https://doi.org/10.1007/s005350070081
  • Reznik, Y., Dao, T., Coutant, R., Chiche, L., Jeannot, E., Clauin, S., Rousselot, P., Fabre, M., Oberti, F., Fatome, A., Zucman-Rossi, J., & Bellanne-Chantelot, C. (2004). Hepatocyte nuclear factor-1 alpha gene inactivation: cosegregation between liver adenomatosis and diabetes phenotypes in two maturity-onset diabetes of the young (MODY)3 families. The Journal of Clinical Endocrinology and Metabolism, 89 (3), 1476-1480. https://doi.org/10.1210/jc.2003-031552
  • Rubin, R. A., & Mitchell, D. G. (1996). Evaluation of the solid hepatic mass. The Medical clinics of North America, 80 (5), 907-928. https://doi.org/10.1016/s0025-7125(05)70473-9
  • Sherlock S. (1975). Hepatic adenomas and oral contraceptives. Gut, 16 (9), 753-756. https://doi.org/10.1136/gut.16.9.753
  • Talente, G. M., Coleman, R. A., Alter, C., Baker, L., Brown, B. I., Cannon, R. A., Chen, Y. T., Crigler, J. F., Jr, Ferreira, P., Haworth, J. C., Herman, G. E., Issenman, R. M., Keating, J. P., Linde, R., Roe, T. F., Senior, B., & Wolfsdorf, J. I. (1994). Glycogen storage disease in adults. Annals of Internal Medicine, 120 (3), 218-226. https://doi.org/10.7326/0003-4819-120-3-199402010-00008
  • Touraine, R. L., Bertrand, Y., Foray, P., Gilly, J., & Philippe, N. (1993). Hepatic tumours during androgen therapy in Fanconi anaemia. European Journal of Pediatrics, 152 (8), 691-693. https://doi.org/10.1007/BF01955250

Rare Cause of Pelvic Mass: Hepatocellular Adenoma

Year 2024, Volume: 8 Issue: 1, 61 - 66, 01.06.2024
https://doi.org/10.47947/ijnls.1487910

Abstract

Introduction: Hepatocellular adenoma (HA) is a rare solitary tumor originating from liver cells. There have been no reported cases with pelvic localization in the literature. In this article, we present a case of HA presenting with a pelvic mass.
Case: A 24-year-old male patient was found to have an intraabdominal mass on ultrasound during routine health screening. MRI (Magnetic Resonance Imaging) showed a solid mass lesion with pelvic localization, extending towards the upper abdomen, measuring approximately 16.5x8 cm, with sharp margins and well-defined borders, primarily suggestive of sarcomatous pathologies (rhabdomyosarcoma? / embryonal sarcoma?). Exploration revealed a mass resembling liver tissue attached to the left lobe of the liver via the falciform ligament, which was excised along with the ligament. The pathology of the specimen was consistent with adenoma. The patient was discharged on the third day postoperatively. Follow-up MRI at six months postoperatively did not reveal any issues.
Discussion and Conclusion: In patients with no significant etiological factors such as oral contraceptive use or anabolic androgen use, genetic studies and identification of possible environmental etiological factors from appropriate case series will contribute significantly to the literature. Our case demonstrated that even in male patients, HA should be considered in the differential diagnosis of intraabdominal masses.

References

  • Bacq, Y., Jacquemin, E., Balabaud, C., Jeannot, E., Scotto, B., Branchereau, S., Laurent, C., Bourlier, P., Pariente, D., de Muret, A., Fabre, M., Bioulac-Sage, P., & Zucman-Rossi, J. (2003). Familial liver adenomatosis associated with hepatocyte nuclear factor 1alpha inactivation. Gastroenterology, 125 (5), 1470-1475. https://doi.org/10.1016/j.gastro.2003.07.012
  • Bala, S., Wünsch, P. H., & Ballhausen, W. G. (1997). Childhood hepatocellular adenoma in familial adenomatous polyposis: mutations in adenomatous polyposis coli gene and p53. Gastroenterology, 112 (3), 919-922. https://doi.org/10.1053/gast.1997.v112.pm9041254
  • Baum, J. K., Bookstein, J. J., Holtz, F., & Klein, E. W. (1973). Possible association between benign hepatomas and oral contraceptives. Lancet (London, England), 2 (7835), 926-929. https://doi.org/10.1016/s0140-6736(73)92594-4
  • Bieze, M., Phoa, S. S., Verheij, J., van Lienden, K. P., & van Gulik, T. M. (2014). Risk factors for bleeding in hepatocellular adenoma. The British Journal of Surgery, 10 1(7), 847-855. https://doi.org/10.1002/bjs.9493
  • Bioulac-Sage, P., Sempoux, C., & Balabaud, C. (2017). Hepatocellular adenoma: Classification, variants and clinical relevance. Seminars in Diagnostic Pathology, 34 (2), 112-125. https://doi.org/10.1053/j.semdp.2016.12.007
  • Coombes, G. B., Reiser, J., Paradinas, F. J., & Burn, I. (1978). An androgen-associated hepatic adenoma in a trans-sexual. The British Journal of Surgery, 65 (12), 869-870. https://doi.org/10.1002/bjs.1800651212
  • Foster, J. H., & Berman, M. M. (1994). The malignant transformation of liver cell adenomas. Archives of Surgery (Chicago, Ill. : 1960), 129 (7), 712–717. https://doi.org/10.1001/archsurg.1994.01420310044007
  • Fujiyama, S., Sato, K., Sakai, M., Sato, T., Tashiro, S., & Arakawa, M. (1990). A case of type Ia glycogen storage disease complicated by hepatic adenoma. Hepato-Gastroenterology, 37 (4), 432-435.
  • Grazioli, L., Federle, M. P., Brancatelli, G., Ichikawa, T., Olivetti, L., & Blachar, A. (2001). Hepatic adenomas: imaging and pathologic findings. Radiographics: a review publication of the Radiological Society of North America, Inc, 21 (4), 877-894. https://doi.org/10.1148/radiographics.21.4.g01jl04877
  • Klatskin G. (1977). Hepatic tumors: possible relationship to use of oral contraceptives. Gastroenterology, 73 (2), 386-394.
  • Labrune, P., Trioche, P., Duvaltier, I., Chevalier, P., & Odièvre, M. (1997). Hepatocellular adenomas in glycogen storage disease type I and III: a series of 43 patients and review of the literature. Journal of Pediatric Gastroenterology and Nutrition, 24 (3), 276-279. https://doi.org/10.1097/00005176-199703000-00008
  • Nakao, A., Sakagami, K., Nakata, Y., Komazawa, K., Amimoto, T., Nakashima, K., Isozaki, H., Takakura, N., & Tanaka, N. (2000). Multiple hepatic adenomas caused by long-term administration of androgenic steroids for aplastic anemia in association with familial adenomatous polyposis. Journal of Gastroenterology, 35 (7), 557-562. https://doi.org/10.1007/s005350070081
  • Reznik, Y., Dao, T., Coutant, R., Chiche, L., Jeannot, E., Clauin, S., Rousselot, P., Fabre, M., Oberti, F., Fatome, A., Zucman-Rossi, J., & Bellanne-Chantelot, C. (2004). Hepatocyte nuclear factor-1 alpha gene inactivation: cosegregation between liver adenomatosis and diabetes phenotypes in two maturity-onset diabetes of the young (MODY)3 families. The Journal of Clinical Endocrinology and Metabolism, 89 (3), 1476-1480. https://doi.org/10.1210/jc.2003-031552
  • Rubin, R. A., & Mitchell, D. G. (1996). Evaluation of the solid hepatic mass. The Medical clinics of North America, 80 (5), 907-928. https://doi.org/10.1016/s0025-7125(05)70473-9
  • Sherlock S. (1975). Hepatic adenomas and oral contraceptives. Gut, 16 (9), 753-756. https://doi.org/10.1136/gut.16.9.753
  • Talente, G. M., Coleman, R. A., Alter, C., Baker, L., Brown, B. I., Cannon, R. A., Chen, Y. T., Crigler, J. F., Jr, Ferreira, P., Haworth, J. C., Herman, G. E., Issenman, R. M., Keating, J. P., Linde, R., Roe, T. F., Senior, B., & Wolfsdorf, J. I. (1994). Glycogen storage disease in adults. Annals of Internal Medicine, 120 (3), 218-226. https://doi.org/10.7326/0003-4819-120-3-199402010-00008
  • Touraine, R. L., Bertrand, Y., Foray, P., Gilly, J., & Philippe, N. (1993). Hepatic tumours during androgen therapy in Fanconi anaemia. European Journal of Pediatrics, 152 (8), 691-693. https://doi.org/10.1007/BF01955250
There are 17 citations in total.

Details

Primary Language English
Subjects Health Services and Systems (Other)
Journal Section Case report
Authors

Mücahit Ünal 0000-0001-9941-5166

Şener Balas 0000-0002-9154-3179

Publication Date June 1, 2024
Submission Date May 22, 2024
Acceptance Date May 28, 2024
Published in Issue Year 2024 Volume: 8 Issue: 1

Cite

APA Ünal, M., & Balas, Ş. (2024). Rare Cause of Pelvic Mass: Hepatocellular Adenoma. International Journal of Nature and Life Sciences, 8(1), 61-66. https://doi.org/10.47947/ijnls.1487910