Some biological activities of Thalictrum minus (Ranunculaceae)

Abstract

Plants are vital natural resources that are used in a wide range of applications. Throughout history, these tools have proven to be valuable assets for individuals. We conducted a study to assess the biological activity of the aerial portions of Thalictrum minus L. In this particular situation, the plant's ethanol and methanol extracts were obtained using Soxhlet equipment. The Rel Assay kits were used to measure the total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI). The antiproliferative effectiveness against the A549 lung cancer cell line was assessed using the MTT test. The anticholinesterase activity was assessed by measuring the activities of acetylcholinesterase and butyrylcholinesterase. The plant's ethanol and methanol extracts were analyzed, and their TAS values were determined to be 4.371±0.083 and 4.027±0.081, respectively. The TOS values were determined to be 11.816±0.121 and 13.580±0.176, respectively, whereas the OSI values were determined to be 0.271±0.007 and 0.337±0.009. The antiproliferative activity of the methanol extract of the plant was found to be greater than that of the ethanol extract. The ethanol extract had an anti-AChE value of 58.90±1.41, while the methanol extract had an anti-AChE value of 65.11±1.01. Similarly, the ethanol extract had an anti-BChE value of 72.25±0.79, while the methanol extract had an anti-BChE value of 85.79±0.68. Consequently, it was established that the plant has antioxidant, anticancer, and anticholinesterase properties.

Keywords

• Antioxidant
• Anticholinesterase
• Medicinal plants
• Ranunculaceae
• Thalictrum minus

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